3KJ4

structure of rat nogo receptor bound to 1d9 antagonist antibody

• Total interactions analyzed: 15
• Total true interactions: 6
• Strongest Interaction:
  • Chains: L-H
  • Int. Res.: 190
  • Norm. En. per Res.: -2.8388
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-31.5734	-21.5862	-486.219	-539.3786	190	19	6	18465	1	11	8
L-A	-4.6079	9.6833	-59.6603	-54.5849	34	2	0	2595	0	5	4
H-A	-30.5029	0.0	-138.844	-169.3469	61	14	3	5348	0	1	1
B-C	-32.0933	-20.7002	-464.156	-516.9494	184	20	6	17987	1	11	9
B-D	-10.0616	7.824	-63.0332	-65.2708	36	4	0	2612	0	4	4
C-D	-23.4274	0.0	-113.069	-136.4964	54	3	2	4156	0	1	1

Interface residues

• L-H: ALA105H, ALA108H, ALA132H, ALA135L, ALA136H, ALA137H, ALA175H, ALA40L, ALA57L, ALA96H, ARG220H, ARG38H, ARG60L, ARG97H, ASN140H, ASN142L, ASN143L, ASN166L, ASN215L, ASN31L, ASN34L, ASN37L, ASN60H, ASP170L, ASP172L, ASP175L, CYS139L, CYS147H, CYS219L, CYS94L, CYS95H, GLN112H, GLN129L, GLN178H, GLN39H, GLN43H, GLN43L, GLN44L, GLN48L, GLN6L, GLN96L, GLU103H, GLU128L, GLU218L, GLU46H, GLU61L, GLU6H, GLY104H, GLY104L, GLY106L, GLY111H, GLY113H, GLY134H, GLY134L, GLY146H, GLY169H, GLY42H, GLY44H, GLY47L, GLY49H, GLY99H, HIS171H, HIS35H, HIS58H, ILE100H, ILE122L, ILE217H, ILE54L, ILE92H, LEU100L, LEU130L, LEU131H, LEU141L, LEU145H, LEU148H, LEU165L, LEU177H, LEU181H, LEU184H, LEU184L, LEU186L, LEU39L, LEU45H, LEU48H, LEU53L, LYS150H, LYS174L, LYS212L, LYS215H, LYS216H, LYS36L, LYS51L, MET142H, MET180L, MET95L, PHE101L, PHE103L, PHE107H, PHE123L, PHE140L, PHE144L, PHE173H, PHE214L, PRO118L, PRO124L, PRO125L, PRO130H, PRO133H, PRO174H, PRO50L, PRO52L, SER105L, SER121L, SER126L, SER127H, SER127L, SER132L, SER135H, SER136L, SER167H, SER167L, SER168H, SER173L, SER179H, SER179L, SER181L, SER182L, SER185H, SER186H, SER187H, SER213L, SER40H, SER49L, SER62L, SER97L, THR102L, THR114H, THR119L, THR131L, THR139H, THR144H, THR169L, THR172H, THR177L, THR183H, THR183L, THR185L, THR187L, THR189H, THR59L, TRP106H, TRP110H, TRP161H, TRP168L, TRP195H, TRP36H, TRP41L, TRP47H, TRP52H, TRP56L, TYR101H, TYR102H, TYR109H, TYR129H, TYR178L, TYR182H, TYR38L, TYR42L, TYR55L, TYR59H, TYR92L, TYR93L, TYR94H, TYR98L, VAL120L, VAL128H, VAL137L, VAL138L, VAL143H, VAL149H, VAL164L, VAL170H, VAL176H, VAL188H, VAL218H, VAL37H, VAL50H, VAL64L, VAL91L, VAL98H
• L-A: ALA50A, ALA74A, ALA92A, ALA94A, ARG119A, ARG33L, ARG35L, ASN31L, ASN34L, ASP122A, ASP97A, GLN117A, GLN143A, GLN49A, GLY95A, ILE69A, ILE96A, LEU118A, LEU48A, LEU93A, LYS36L, PRO73A, SER32L, SER70A, THR59L, TRP56L, TYR38L, TYR55L, TYR71A, TYR98L, VAL120A, VAL121A, VAL51A, VAL72A
• H-A: ALA105H, ALA50A, ALA57A, ALA74A, ALA75A, ARG81A, ARG97H, ASN56H, ASN67A, ASN73H, CYS27A, CYS33A, CYS80A, GLN49A, GLN78A, GLU103H, GLY103A, GLY104H, GLY29A, GLY33H, GLY47A, GLY54A, GLY54H, GLY55H, GLY99H, HIS35H, HIS58H, ILE100H, ILE51H, ILE55A, ILE69A, LEU29H, LEU48A, LYS71H, PHE27H, PHE77A, PRO28A, PRO52A, PRO56A, PRO73A, SER28H, SER30H, SER31H, SER53H, SER58A, SER59A, SER70A, SER76A, SER79A, THR53A, THR57H, TRP106H, TRP52H, TYR101H, TYR102H, TYR109H, TYR32H, TYR71A, VAL51A, VAL72A, VAL98H
• B-C: ALA105C, ALA108C, ALA132C, ALA135B, ALA136C, ALA175C, ALA40B, ALA57B, ALA62C, ALA96C, ARG220C, ARG38C, ARG60B, ARG97C, ASN140C, ASN142B, ASN143B, ASN166B, ASN34B, ASN37B, ASN60C, ASN99B, ASP170B, ASP172B, ASP175B, ASP1B, CYS139B, CYS147C, CYS219B, CYS94B, CYS95C, GLN112C, GLN129B, GLN171B, GLN178C, GLN39C, GLN43B, GLN43C, GLN44B, GLN48B, GLN6B, GLN96B, GLU103C, GLU128B, GLU218B, GLU46C, GLU61B, GLU6C, GLY104B, GLY104C, GLY106B, GLY111C, GLY113C, GLY134B, GLY134C, GLY146C, GLY163B, GLY169C, GLY42C, GLY44C, GLY47B, GLY49C, HIS171C, HIS35C, HIS58C, ILE122B, ILE217C, ILE54B, ILE92C, LEU100B, LEU130B, LEU131C, LEU141B, LEU145C, LEU148C, LEU165B, LEU177C, LEU181C, LEU184B, LEU184C, LEU186B, LEU39B, LEU45C, LEU48C, LEU4C, LEU53B, LYS150C, LYS174B, LYS212B, LYS215C, LYS216C, LYS36B, LYS51B, MET142C, MET180B, MET95B, PHE101B, PHE103B, PHE107C, PHE123B, PHE140B, PHE144B, PHE173C, PHE214B, PRO124B, PRO125B, PRO130C, PRO133C, PRO174C, PRO41C, PRO50B, PRO52B, SER105B, SER121B, SER126B, SER127B, SER127C, SER132B, SER135C, SER136B, SER167B, SER168C, SER173B, SER179B, SER179C, SER181B, SER182B, SER185C, SER186C, SER187C, SER40C, SER49B, SER61C, SER62B, SER97B, THR102B, THR114C, THR119B, THR131B, THR144C, THR169B, THR172C, THR177B, THR183B, THR183C, THR185B, THR189C, THR59B, TRP106C, TRP110C, TRP161C, TRP168B, TRP195C, TRP36C, TRP41B, TRP47C, TRP52C, TRP56B, TYR102C, TYR109C, TYR129C, TYR178B, TYR38B, TYR42B, TYR55B, TYR59C, TYR92B, TYR93B, TYR94C, TYR98B, VAL120B, VAL128C, VAL137B, VAL138B, VAL143C, VAL149C, VAL164B, VAL170C, VAL176C, VAL188C, VAL218C, VAL37C, VAL50C, VAL91B
• B-D: ALA50D, ALA74D, ALA92D, ALA94D, ARG119D, ARG33B, ARG35B, ARG68D, ASN31B, ASN34B, ASP122D, ASP97D, GLN117D, GLN143D, GLN49D, GLY95D, ILE69D, ILE96D, LEU118D, LEU48D, LEU93D, LYS36B, PRO52D, PRO73D, SER32B, SER70D, THR59B, TRP56B, TYR38B, TYR55B, TYR71D, TYR98B, VAL120D, VAL121D, VAL51D, VAL72D
• C-D: ALA105C, ALA50D, ALA57D, ALA74D, ALA75D, ARG81D, ARG97C, ASN56C, ASN73C, CYS27D, CYS80D, GLN49D, GLN78D, GLU103C, GLY103D, GLY104C, GLY29D, GLY33C, GLY47D, GLY54C, GLY54D, GLY55C, HIS35C, HIS58C, ILE55D, ILE69D, LEU29C, LEU48D, LYS71C, PHE107C, PHE27C, PHE77D, PRO28D, PRO52D, PRO56D, PRO73D, SER28C, SER30C, SER31C, SER53C, SER58D, SER59D, SER76D, SER79D, THR53D, THR57C, TRP106C, TRP52C, TYR102C, TYR109C, TYR32C, TYR71D, VAL51D, VAL72D