3KGL

crystal structure of procruciferin, 11s globulin from brassica napus

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: D-E
  • Int. Res.: 239
  • Norm. En. per Res.: -4.621
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-120.2863	-16.7152	-800.891	-937.8925	244	57	19	32884	5	49	48
A-C	-166.9927	-81.6724	-773.305	-1021.9701	239	56	19	31853	9	47	48
A-D	-73.7446	22.1498	-126.959	-178.5538	75	19	0	5323	1	30	31
A-E	-12.4208	4.0298	-48.3215	-56.7125	35	5	0	1966	0	2	3
B-C	-148.8582	-48.6274	-799.73	-997.2156	236	56	20	32692	5	44	44
B-D	0.0	6.2127	-10.2537	-4.041	27	0	0	719	0	2	3
B-F	-94.2089	5.5527	-146.318	-234.9742	69	17	0	5506	1	31	34
C-E	-46.854	17.8852	-146.112	-175.0808	75	18	0	5406	1	29	33
C-F	0.0	6.781	-20.3553	-13.5742	25	0	0	1145	0	2	4
D-E	-171.943	-76.1692	-856.311	-1104.4232	239	57	19	33637	7	46	47
D-F	-98.8982	-17.6698	-817.827	-934.395	238	51	18	32447	9	48	48
E-F	-140.8662	-73.9753	-795.315	-1010.1565	243	50	18	32479	9	46	49

Interface residues

• A-B: ALA162A, ALA182B, ALA198A, ALA229A, ALA231A, ALA239A, ALA342B, ALA344B, ALA346B, ALA404B, ALA406B, ALA412B, ALA437B, ALA64A, ALA84A, ARG140A, ARG190A, ARG193A, ARG211A, ARG237A, ARG249A, ARG254A, ARG263A, ARG319B, ARG322A, ARG322B, ARG366B, ARG389B, ARG39A, ARG39B, ARG414B, ARG419B, ARG438B, ARG439B, ARG78A, ASN186A, ASN191A, ASN200A, ASN201A, ASN218A, ASN221A, ASN244A, ASN248A, ASN251A, ASN333B, ASN341B, ASN343B, ASN345B, ASN361B, ASN363B, ASN403B, ASN405B, ASN409B, ASN428B, ASN443B, ASN5B, ASP10B, ASP141A, ASP180B, ASP189A, ASP235A, ASP247A, ASP362B, ASP365B, ASP369B, ASP89A, CYS40B, CYS7B, CYS83A, GLN144A, GLN163A, GLN185A, GLN187A, GLN205A, GLN213A, GLN214A, GLN216A, GLN240A, GLN241A, GLN243A, GLN245A, GLN256A, GLN2A, GLN339B, GLN358B, GLN382B, GLN407B, GLN431B, GLN8B, GLU209A, GLU212A, GLU226A, GLU24A, GLU424B, GLU435B, GLU436B, GLU446B, GLU6A, GLU6B, GLU85A, GLY160A, GLY199A, GLY204A, GLY210A, GLY222A, GLY250A, GLY257A, GLY364B, GLY383B, GLY413B, GLY420B, GLY429B, GLY42B, GLY454B, GLY77A, GLY82A, GLY96A, HIS143A, HIS158A, HIS184A, HIS184B, HIS33A, HIS34A, HIS356B, HIS451B, ILE208A, ILE219A, ILE234A, ILE253A, ILE262A, ILE282A, ILE380B, ILE408B, ILE426B, ILE432B, ILE445B, LEU188A, LEU197A, LEU220A, LEU228A, LEU242A, LEU304B, LEU323B, LEU337B, LEU411B, LEU418B, LEU421B, LEU423B, LEU434B, LEU449B, LEU55A, LEU57A, LEU75A, LEU9B, LYS145A, LYS217A, LYS230A, LYS233A, LYS388B, LYS401B, LYS441B, MET142A, MET335B, MET76A, PHE139A, PHE165A, PHE195A, PHE223A, PHE232A, PHE259A, PHE320A, PHE368B, PHE384B, PHE3A, PHE3B, PHE442B, PHE60A, PHE61A, PHE87A, PRO159A, PRO192A, PRO194A, PRO215A, PRO225A, PRO258A, PRO338B, PRO381B, PRO422B, PRO455B, PRO4B, PRO58A, PRO81A, PRO95A, SER183B, SER260A, SER385B, SER416B, SER41B, SER427B, SER433B, SER452B, SER453B, SER59A, SER62A, SER90A, SER91A, THR224A, THR238A, THR281A, THR402B, THR410B, THR415B, THR444B, THR447B, THR450B, THR63A, THR86A, TRP164A, TRP207A, TRP340B, TYR166A, TYR196A, TYR313B, TYR430B, TYR56A, VAL146A, VAL161A, VAL227A, VAL255A, VAL261A, VAL336B, VAL357B, VAL359B, VAL360B, VAL367B, VAL386B, VAL387B, VAL417B, VAL425B, VAL43B, VAL440B, VAL79A, VAL80A, VAL92A
• A-C: ALA162C, ALA182A, ALA198C, ALA229C, ALA231C, ALA239C, ALA342A, ALA344A, ALA346A, ALA404A, ALA406A, ALA412A, ALA437A, ALA64C, ALA84C, ARG140C, ARG190A, ARG190C, ARG193C, ARG211C, ARG237C, ARG249C, ARG254C, ARG263C, ARG319A, ARG322A, ARG366A, ARG389A, ARG39A, ARG39C, ARG414A, ARG419A, ARG438A, ARG439A, ARG78C, ASN186C, ASN191C, ASN200C, ASN201C, ASN218C, ASN221C, ASN244C, ASN248C, ASN251C, ASN333A, ASN341A, ASN343A, ASN345A, ASN361A, ASN363A, ASN403A, ASN405A, ASN409A, ASN428A, ASN443A, ASN5A, ASP10A, ASP141C, ASP180A, ASP189C, ASP235C, ASP247C, ASP362A, ASP365A, ASP369A, CYS283C, CYS40A, CYS7A, CYS83C, GLN144C, GLN163C, GLN185C, GLN187C, GLN1A, GLN205C, GLN214C, GLN216C, GLN240C, GLN241C, GLN243C, GLN245C, GLN256C, GLN2A, GLN339A, GLN358A, GLN382A, GLN407A, GLN431A, GLN8A, GLU209C, GLU212C, GLU226C, GLU24C, GLU280C, GLU424A, GLU435A, GLU436A, GLU446A, GLU6A, GLU85C, GLY160C, GLY199C, GLY204C, GLY210C, GLY222C, GLY250C, GLY257C, GLY364A, GLY383A, GLY413A, GLY420A, GLY429A, GLY42A, GLY77C, GLY82C, HIS143C, HIS158C, HIS184A, HIS184C, HIS33C, HIS34C, HIS356A, HIS451A, ILE208C, ILE219C, ILE234C, ILE253C, ILE262C, ILE282C, ILE380A, ILE408A, ILE426A, ILE432A, ILE445A, LEU181C, LEU188C, LEU197C, LEU220C, LEU228C, LEU242C, LEU304A, LEU323A, LEU337A, LEU411A, LEU418A, LEU421A, LEU423A, LEU434A, LEU449A, LEU55C, LEU57C, LEU75C, LEU9A, LYS145C, LYS217C, LYS230C, LYS233C, LYS388A, LYS401A, LYS441A, LYS53C, MET142C, MET335A, PHE165C, PHE195C, PHE223C, PHE232C, PHE259C, PHE320C, PHE368A, PHE384A, PHE3A, PHE3C, PHE442A, PHE60C, PHE61C, PRO159C, PRO192C, PRO194C, PRO215C, PRO225C, PRO258C, PRO264C, PRO338A, PRO381A, PRO422A, PRO4A, PRO58C, PRO81C, SER183A, SER183C, SER260C, SER312A, SER385A, SER416A, SER41A, SER427A, SER433A, SER452A, SER453A, SER59C, SER62C, THR224C, THR238C, THR281C, THR402A, THR410A, THR415A, THR444A, THR447A, THR450A, THR63C, THR86C, TRP164C, TRP207C, TRP340A, TYR166C, TYR196C, TYR313A, TYR430A, TYR56C, VAL146C, VAL161C, VAL227C, VAL255C, VAL261C, VAL336A, VAL357A, VAL359A, VAL360A, VAL367A, VAL386A, VAL387A, VAL417A, VAL425A, VAL43A, VAL440A, VAL79C, VAL80C
• A-D: ALA14A, ALA14D, ALA35A, ALA35D, ARG211A, ARG211D, ARG39A, ARG39D, ASN13A, ASN13D, ASP10D, ASP32A, ASP32D, CYS40D, GLN11A, GLN11D, GLN1A, GLN213A, GLN213D, GLN214A, GLN214D, GLN2A, GLN2D, GLN376A, GLN376D, GLN37A, GLN37D, GLU16A, GLU16D, GLU209A, GLU209D, GLU212A, GLU212D, GLY210A, GLY210D, HIS19A, HIS19D, HIS33A, HIS34A, HIS34D, ILE208A, ILE208D, LEU12A, LEU12D, LEU15A, LEU15D, LEU377A, LEU377D, LEU378A, LEU378D, LEU38A, LEU38D, LEU9A, LEU9D, LYS217A, LYS217D, PHE368D, PHE3A, PRO17A, PRO17D, PRO215A, PRO215D, PRO36A, PRO36D, SER18A, SER18D, SER379A, SER379D, TRP31A, TRP31D, VAL206A, VAL206D, VAL30A, VAL30D, VAL367D
• A-E: ALA35A, ALA35E, ARG39A, ARG39E, ASN13E, ASN363A, ASN363E, ASN5A, ASN5E, ASP10A, ASP10E, ASP365A, ASP365E, GLN11A, GLN11E, GLN1A, GLN1E, GLN2A, GLN2E, GLN37A, GLN37E, GLN8A, GLN8E, GLU6A, GLU6E, HIS34A, HIS34E, LEU9A, LEU9E, PHE3A, PHE3E, PRO36A, PRO36E, PRO4A, PRO4E
• B-C: ALA162B, ALA182C, ALA198B, ALA229B, ALA231B, ALA239B, ALA342C, ALA344C, ALA346C, ALA404C, ALA406C, ALA412C, ALA437C, ALA64B, ALA84B, ARG190B, ARG190C, ARG193B, ARG211B, ARG237B, ARG249B, ARG254B, ARG319C, ARG322B, ARG322C, ARG366C, ARG389C, ARG39B, ARG39C, ARG414C, ARG419C, ARG438C, ARG439C, ARG78B, ASN186B, ASN191B, ASN200B, ASN201B, ASN218B, ASN221B, ASN244B, ASN248B, ASN251B, ASN333C, ASN341C, ASN343C, ASN345C, ASN361C, ASN363C, ASN403C, ASN405C, ASN409C, ASN428C, ASN443C, ASN5C, ASP10C, ASP141B, ASP180C, ASP189B, ASP235B, ASP247B, ASP362C, ASP365C, ASP369C, CYS40C, CYS7C, CYS83B, GLN144B, GLN163B, GLN185B, GLN187B, GLN1C, GLN205B, GLN214B, GLN216B, GLN240B, GLN241B, GLN243B, GLN245B, GLN256B, GLN2C, GLN339C, GLN358C, GLN382C, GLN407C, GLN431C, GLN8C, GLU209B, GLU212B, GLU226B, GLU24B, GLU280B, GLU424C, GLU435C, GLU436C, GLU446C, GLU6B, GLU6C, GLU85B, GLY160B, GLY199B, GLY204B, GLY210B, GLY222B, GLY250B, GLY257B, GLY364C, GLY383C, GLY413C, GLY420C, GLY429C, GLY42C, GLY454C, GLY77B, GLY82B, HIS143B, HIS158B, HIS184B, HIS184C, HIS33B, HIS34B, HIS356C, HIS451C, ILE208B, ILE219B, ILE234B, ILE253B, ILE262B, ILE282B, ILE380C, ILE408C, ILE426C, ILE432C, ILE445C, LEU188B, LEU197B, LEU220B, LEU228B, LEU242B, LEU304C, LEU337C, LEU411C, LEU418C, LEU421C, LEU423C, LEU434C, LEU449C, LEU55B, LEU57B, LEU75B, LEU9C, LYS145B, LYS217B, LYS230B, LYS233B, LYS388C, LYS401C, LYS441C, MET142B, MET335C, MET76B, PHE165B, PHE195B, PHE223B, PHE232B, PHE259B, PHE320B, PHE368C, PHE384C, PHE3B, PHE3C, PHE442C, PHE60B, PHE61B, PRO159B, PRO192B, PRO194B, PRO215B, PRO225B, PRO258B, PRO338C, PRO381C, PRO422C, PRO455C, PRO4B, PRO4C, PRO58B, PRO81B, SER183C, SER260B, SER312C, SER385C, SER416C, SER41C, SER427C, SER433C, SER452C, SER453C, SER59B, SER62B, THR224B, THR238B, THR281B, THR402C, THR410C, THR415C, THR444C, THR450C, THR63B, TRP164B, TRP207B, TRP340C, TYR166B, TYR196B, TYR313C, TYR430C, TYR56B, VAL146B, VAL161B, VAL227B, VAL236B, VAL255B, VAL261B, VAL336C, VAL357C, VAL359C, VAL360C, VAL367C, VAL386C, VAL387C, VAL417C, VAL425C, VAL43C, VAL440C, VAL79B, VAL80B
• B-D: ARG39B, ARG39D, ASN363B, ASN363D, ASN5B, ASN5D, ASP10B, ASP10D, ASP365B, ASP365D, CYS7B, GLN11B, GLN11D, GLN2D, GLN8B, GLN8D, GLU209D, GLU6B, HIS34B, HIS34D, LEU9B, PHE3B, PHE3D, PRO36B, PRO36D, PRO4B, PRO4D
• B-F: ALA14B, ALA14F, ALA35B, ALA35F, ARG211B, ARG211F, ARG39B, ARG39F, ASN13B, ASN13F, ASP10B, ASP10F, ASP32B, ASP32F, CYS40B, GLN11B, GLN11F, GLN213B, GLN213F, GLN214B, GLN214F, GLN376B, GLN376F, GLN37B, GLN37F, GLU16B, GLU16F, GLU209B, GLU209F, GLU212B, GLU212F, GLY210B, GLY210F, HIS19B, HIS19F, HIS34B, HIS34F, ILE208B, ILE208F, LEU12B, LEU12F, LEU15B, LEU15F, LEU377B, LEU377F, LEU378B, LEU378F, LEU38B, LEU38F, LEU9B, LEU9F, LYS217F, PRO17B, PRO17F, PRO215B, PRO215F, PRO36B, PRO36F, SER18B, SER18F, SER379B, SER379F, TRP31B, TRP31F, VAL206B, VAL206F, VAL20B, VAL30B, VAL30F
• C-E: ALA14C, ALA14E, ALA35C, ALA35E, ARG193E, ARG211C, ARG211E, ARG39C, ARG39E, ASN13C, ASN13E, ASN191E, ASP32C, ASP32E, CYS40C, GLN11C, GLN11E, GLN1C, GLN1E, GLN213C, GLN213E, GLN214C, GLN214E, GLN2C, GLN2E, GLN376C, GLN376E, GLN37C, GLN37E, GLU16C, GLU16E, GLU209C, GLU209E, GLU212C, GLU212E, GLY210C, GLY210E, HIS19C, HIS19E, HIS33C, HIS33E, HIS34C, HIS34E, ILE208C, ILE208E, LEU12C, LEU12E, LEU15C, LEU15E, LEU377C, LEU377E, LEU378C, LEU38C, LEU38E, LEU9C, LEU9E, LYS217C, PHE368E, PRO17C, PRO17E, PRO215C, PRO215E, PRO36C, PRO36E, SER18C, SER18E, SER379C, SER379E, TRP31C, TRP31E, VAL206C, VAL206E, VAL30C, VAL30E, VAL367E
• C-F: ALA35F, ARG39C, ARG39F, ASN363C, ASN5C, ASN5F, ASP10C, ASP10F, ASP365C, CYS40F, CYS7F, GLN11C, GLN11F, GLN1C, GLN2C, GLN37F, GLN8C, GLN8F, GLU6F, LEU9F, PHE3C, PHE3F, PRO36C, PRO36F, PRO4F
• D-E: ALA162D, ALA182E, ALA198D, ALA229D, ALA231D, ALA239D, ALA342E, ALA344E, ALA346E, ALA412E, ALA437E, ALA64D, ALA84D, ARG140D, ARG190D, ARG190E, ARG193D, ARG211D, ARG237D, ARG249D, ARG254D, ARG319E, ARG322D, ARG322E, ARG366E, ARG389E, ARG39D, ARG39E, ARG414E, ARG419E, ARG438E, ARG439E, ARG78D, ASN186D, ASN191D, ASN200D, ASN201D, ASN218D, ASN221D, ASN244D, ASN248D, ASN251D, ASN333E, ASN341E, ASN343E, ASN345E, ASN361E, ASN363E, ASN403E, ASN405E, ASN409E, ASN428E, ASN443E, ASN5E, ASP10E, ASP141D, ASP180E, ASP189D, ASP235D, ASP247D, ASP362E, ASP365E, ASP369E, CYS283D, CYS40E, CYS7E, CYS83D, GLN11E, GLN144D, GLN163D, GLN185D, GLN187D, GLN1E, GLN205D, GLN214D, GLN216D, GLN240D, GLN241D, GLN243D, GLN245D, GLN256D, GLN2E, GLN339E, GLN358E, GLN382E, GLN407E, GLN431E, GLN8E, GLU209D, GLU212D, GLU226D, GLU24D, GLU280D, GLU424E, GLU435E, GLU436E, GLU446E, GLU6D, GLU6E, GLU85D, GLY160D, GLY199D, GLY204D, GLY210D, GLY222D, GLY250D, GLY257D, GLY364E, GLY383E, GLY413E, GLY420E, GLY429E, GLY42E, GLY454E, GLY77D, GLY82D, HIS143D, HIS158D, HIS184D, HIS184E, HIS33D, HIS34D, HIS356E, HIS451E, ILE208D, ILE219D, ILE234D, ILE253D, ILE262D, ILE282D, ILE380E, ILE408E, ILE426E, ILE432E, ILE445E, LEU188D, LEU197D, LEU220D, LEU228D, LEU242D, LEU323E, LEU337E, LEU411E, LEU418E, LEU421E, LEU423E, LEU434E, LEU449E, LEU55D, LEU57D, LEU75D, LEU9E, LYS145D, LYS217D, LYS230D, LYS233D, LYS301E, LYS388E, LYS401E, LYS441E, MET142D, MET335E, MET76D, PHE165D, PHE195D, PHE223D, PHE232D, PHE259D, PHE320D, PHE368E, PHE384E, PHE3D, PHE3E, PHE442E, PHE60D, PHE61D, PRO159D, PRO192D, PRO194D, PRO215D, PRO225D, PRO258D, PRO338E, PRO381E, PRO422E, PRO455E, PRO4D, PRO4E, PRO58D, PRO81D, SER183D, SER183E, SER260D, SER312E, SER385E, SER416E, SER41E, SER427E, SER433E, SER452E, SER453E, SER59D, SER62D, THR224D, THR238D, THR281D, THR402E, THR410E, THR415E, THR444E, THR450E, THR63D, TRP164D, TRP207D, TRP340E, TYR166D, TYR196D, TYR313E, TYR430E, TYR56D, VAL146D, VAL161D, VAL227D, VAL236D, VAL255D, VAL261D, VAL336E, VAL357E, VAL359E, VAL360E, VAL367E, VAL386E, VAL387E, VAL417E, VAL425E, VAL43E, VAL440E, VAL79D, VAL80D
• D-F: ALA162F, ALA182D, ALA198F, ALA229F, ALA231F, ALA239F, ALA342D, ALA344D, ALA346D, ALA404D, ALA412D, ALA437D, ALA64F, ALA84F, ARG140F, ARG190D, ARG190F, ARG193F, ARG211F, ARG237F, ARG249F, ARG254F, ARG263F, ARG319D, ARG322D, ARG322F, ARG366D, ARG389D, ARG39D, ARG39F, ARG414D, ARG419D, ARG438D, ARG439D, ARG78F, ASN186F, ASN191F, ASN200F, ASN201F, ASN218F, ASN221F, ASN244F, ASN248F, ASN251F, ASN341D, ASN343D, ASN345D, ASN361D, ASN363D, ASN403D, ASN405D, ASN409D, ASN428D, ASN443D, ASN5D, ASP10D, ASP141F, ASP180D, ASP189F, ASP235F, ASP247F, ASP362D, ASP365D, ASP369D, ASP89F, CYS283F, CYS40D, CYS7D, CYS83F, GLN144F, GLN163F, GLN185F, GLN187F, GLN205F, GLN214F, GLN216F, GLN240F, GLN241F, GLN243F, GLN245F, GLN256F, GLN2D, GLN339D, GLN358D, GLN382D, GLN407D, GLN431D, GLN88F, GLN8D, GLU209F, GLU226F, GLU24F, GLU424D, GLU435D, GLU436D, GLU446D, GLU6D, GLU6F, GLU85F, GLY160F, GLY199F, GLY204F, GLY210F, GLY222F, GLY257F, GLY364D, GLY383D, GLY413D, GLY420D, GLY429D, GLY42D, GLY454D, GLY77F, GLY82F, HIS143F, HIS158F, HIS184D, HIS184F, HIS33F, HIS34F, HIS356D, HIS451D, ILE208F, ILE219F, ILE234F, ILE253F, ILE262F, ILE282F, ILE380D, ILE408D, ILE426D, ILE432D, ILE445D, LEU181F, LEU188F, LEU197F, LEU220F, LEU228F, LEU242F, LEU304D, LEU337D, LEU411D, LEU418D, LEU421D, LEU423D, LEU434D, LEU449D, LEU55F, LEU57F, LEU75F, LEU9D, LYS145F, LYS217F, LYS230F, LYS233F, LYS388D, LYS401D, LYS441D, LYS53F, MET142F, MET335D, PHE139F, PHE165F, PHE195F, PHE223F, PHE232F, PHE259F, PHE320F, PHE368D, PHE384D, PHE3D, PHE3F, PHE442D, PHE60F, PHE61F, PHE87F, PRO159F, PRO192F, PRO194F, PRO215F, PRO225F, PRO258F, PRO338D, PRO381D, PRO422D, PRO455D, PRO4D, PRO58F, PRO81F, SER183D, SER183F, SER260F, SER385D, SER416D, SER41D, SER427D, SER433D, SER452D, SER453D, SER59F, SER62F, THR224F, THR238F, THR281F, THR402D, THR410D, THR415D, THR444D, THR447D, THR450D, THR63F, THR86F, TRP164F, TRP207F, TRP340D, TYR166F, TYR196F, TYR313D, TYR430D, TYR56F, VAL146F, VAL161F, VAL227F, VAL255F, VAL261F, VAL336D, VAL357D, VAL359D, VAL360D, VAL367D, VAL386D, VAL387D, VAL417D, VAL425D, VAL43D, VAL440D, VAL79F, VAL80F
• E-F: ALA162E, ALA182F, ALA198E, ALA229E, ALA231E, ALA239E, ALA342F, ALA344F, ALA346F, ALA404F, ALA406F, ALA412F, ALA437F, ALA64E, ALA84E, ARG140E, ARG190E, ARG190F, ARG193E, ARG211E, ARG237E, ARG249E, ARG254E, ARG263E, ARG319E, ARG319F, ARG322E, ARG322F, ARG366F, ARG389F, ARG39E, ARG39F, ARG414F, ARG419F, ARG438F, ARG439F, ARG78E, ASN186E, ASN191E, ASN200E, ASN201E, ASN218E, ASN221E, ASN244E, ASN248E, ASN251E, ASN333F, ASN341F, ASN343F, ASN345F, ASN361F, ASN363F, ASN403F, ASN405F, ASN409F, ASN428F, ASN443F, ASN5F, ASP10F, ASP141E, ASP180F, ASP189E, ASP235E, ASP247E, ASP362F, ASP365F, ASP369F, CYS283E, CYS40F, CYS7F, CYS83E, GLN144E, GLN163E, GLN185E, GLN187E, GLN205E, GLN214E, GLN216E, GLN240E, GLN241E, GLN243E, GLN256E, GLN339F, GLN358F, GLN382F, GLN407F, GLN431F, GLN8F, GLU209E, GLU212E, GLU226E, GLU24E, GLU280E, GLU424F, GLU435F, GLU436F, GLU446F, GLU6E, GLU6F, GLU85E, GLY138E, GLY160E, GLY199E, GLY204E, GLY210E, GLY222E, GLY250E, GLY257E, GLY364F, GLY383F, GLY413F, GLY420F, GLY429F, GLY42F, GLY454F, GLY77E, GLY82E, HIS143E, HIS158E, HIS184E, HIS184F, HIS33E, HIS34E, HIS356F, HIS451F, ILE208E, ILE219E, ILE234E, ILE253E, ILE262E, ILE282E, ILE380F, ILE408F, ILE426F, ILE432F, ILE445F, LEU188E, LEU197E, LEU220E, LEU228E, LEU242E, LEU304F, LEU323F, LEU337F, LEU411F, LEU418F, LEU421F, LEU423F, LEU434F, LEU449F, LEU55E, LEU57E, LEU75E, LEU9F, LYS145E, LYS217E, LYS230E, LYS233E, LYS301F, LYS388F, LYS401F, LYS441F, MET142E, MET335F, PHE139E, PHE165E, PHE195E, PHE223E, PHE232E, PHE259E, PHE320E, PHE368F, PHE384F, PHE3E, PHE3F, PHE442F, PHE60E, PHE61E, PRO159E, PRO192E, PRO194E, PRO215E, PRO225E, PRO258E, PRO264E, PRO338F, PRO381F, PRO422F, PRO455F, PRO4F, PRO58E, PRO81E, SER183E, SER183F, SER260E, SER312F, SER324F, SER385F, SER416F, SER41F, SER427F, SER433F, SER452F, SER453F, SER59E, SER62E, THR224E, THR238E, THR281E, THR402F, THR410F, THR415F, THR444F, THR447F, THR450F, THR63E, THR86E, TRP164E, TRP207E, TRP340F, TYR166E, TYR196E, TYR313F, TYR430F, TYR56E, VAL146E, VAL161E, VAL227E, VAL255E, VAL261E, VAL336F, VAL357F, VAL359F, VAL360F, VAL367F, VAL386F, VAL387F, VAL417F, VAL425F, VAL43F, VAL440F, VAL79E, VAL80E