3KDO

crystal structure of type iii rubisco sp6 mutant complexed with 2-cabp

• Total interactions analyzed: 45
• Total true interactions: 20
• Strongest Interaction:
  • Chains: E-H
  • Int. Res.: 60
  • Norm. En. per Res.: -5.2275
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-4.2835	-12.2512	-48.813	-65.3476	30	2	0	2210	3	19	12
A-E	-3.98	-10.2336	-53.2156	-67.4292	30	2	0	2163	3	17	12
A-G	-105.3159	-67.9436	-145.315	-318.5745	64	15	0	5980	11	71	56
A-H	-201.3094	-91.5221	-1240.26	-1533.0915	377	58	33	48984	14	57	90
B-C	-14.8539	-13.0002	-54.606	-82.4601	31	2	0	2278	4	18	12
B-F	-88.1724	-49.3602	-164.469	-302.0016	63	20	0	6206	12	71	56
B-G	-214.6091	-107.424	-1279.53	-1601.5632	379	51	31	50267	17	54	89
C-D	-9.0909	-10.5579	-50.3967	-70.0455	30	2	0	2111	4	18	12
C-F	-266.2683	-104.7555	-1322.59	-1693.6138	379	54	33	51495	18	62	89
C-J	-104.3348	-74.7813	-151.579	-330.695	65	11	0	6036	12	72	55
D-E	-4.5177	-13.072	-56.0655	-73.6552	32	4	0	2335	4	18	12
D-I	-89.9878	-47.4153	-155.14	-292.5431	64	14	0	5887	13	67	56
D-J	-284.0132	-123.5601	-1269.61	-1677.1833	375	71	33	50534	19	56	91
E-H	-111.2608	-54.5462	-147.843	-313.6501	60	13	0	5894	12	71	58
E-I	-247.2549	-90.6592	-1272.35	-1610.2642	383	67	32	50446	16	62	89
F-G	-16.1482	-10.8355	-52.7043	-79.688	31	2	0	2216	3	16	12
F-J	-9.4264	-10.2674	-53.8503	-73.5441	30	2	0	2192	5	17	12
G-H	-3.3602	-10.9574	-48.5067	-62.8243	31	2	0	2214	3	17	12
H-I	-7.5411	-10.4767	-50.4108	-68.4286	31	2	0	2119	3	16	11
I-J	0.0	-12.5513	-49.6284	-62.1797	32	2	0	2196	3	17	12

Interface residues

• A-B: ARG134A, ARG201B, ARG23A, ASN200B, ASP137A, GLU130A, GLU135A, GLU171B, GLU172B, GLU204B, GLU98A, GLY167B, ILE133A, ILE208B, ILE359A, LEU132A, LYS131A, LYS22A, LYS355A, PHE173B, PHE93A, PRO129A, PRO170B, PRO197B, SER169B, SER358A, TRP198B, TYR168B, TYR199B, TYR357A
• A-E: ARG134E, ARG201A, ARG23E, ASN200A, ASP137E, GLU130E, GLU135E, GLU171A, GLU172A, GLU204A, GLU98E, GLY167A, ILE133E, ILE208A, ILE359E, LEU132E, LYS131E, LYS22E, LYS355E, PHE173A, PHE93E, PRO129E, PRO170A, PRO197A, SER169A, SER358E, TRP198A, TYR168A, TYR199A, TYR357E
• A-G: ALA68A, ALA68G, ALA72A, ALA72G, ALA95A, ALA95G, ARG134A, ARG134G, ARG23A, ARG23G, ARG66A, ARG66G, ASP24A, ASP24G, ASP69A, ASP69G, GLN64A, GLN64G, GLU130A, GLU130G, GLU135A, GLU135G, GLU63A, GLU63G, GLU65A, GLU65G, GLU98A, GLU98G, HIS341A, HIS341G, HIS94A, HIS94G, LEU70A, LEU70G, LYS131A, LYS131G, LYS21A, LYS21G, LYS22A, LYS22G, LYS355A, LYS355G, LYS73A, LYS73G, PHE93A, PHE93G, PHE96A, PHE96G, PRO92A, PRO92G, SER20A, SER20G, SER71A, SER71G, TRP67A, TRP67G, TYR127G, TYR17A, TYR17G, TYR357A, TYR357G, TYR62A, TYR91A, TYR91G
• A-H: ALA106A, ALA106H, ALA109A, ALA109H, ALA177A, ALA177H, ALA232A, ALA232H, ALA263A, ALA263H, ALA283A, ALA283H, ALA286A, ALA286H, ALA287A, ALA287H, ALA318A, ALA318H, ALA320A, ALA320H, ALA34A, ALA34H, ALA402A, ALA402H, ALA42H, ALA45A, ALA45H, ALA47A, ALA47H, ALA48A, ALA48H, ALA68A, ALA68H, ALA72H, ALA95A, ALA95H, ALA99A, ALA99H, ARG117A, ARG117H, ARG122A, ARG122H, ARG201A, ARG201H, ARG205H, ARG240A, ARG240H, ARG265A, ARG265H, ARG282A, ARG282H, ARG290A, ARG290H, ARG66A, ARG66H, ASN100A, ASN100H, ASN111A, ASN111H, ASN193A, ASN193H, ASN200A, ASN200H, ASN229A, ASN229H, ASN291A, ASN291H, ASN374A, ASN374H, ASP179A, ASP179H, ASP191A, ASP191H, ASP233A, ASP233H, ASP255A, ASP255H, ASP269A, ASP269H, ASP399A, ASP399H, ASP69A, ASP69H, GLN389A, GLN389H, GLN41A, GLN41H, GLN64A, GLN64H, GLU171A, GLU171H, GLU172A, GLU172H, GLU174A, GLU174H, GLU192A, GLU192H, GLU236A, GLU236H, GLU238A, GLU238H, GLU324A, GLU324H, GLU326A, GLU326H, GLU35H, GLU49A, GLU49H, GLU63A, GLU63H, GLU65A, GLU65H, GLU97A, GLU97H, GLU98A, GLU98H, GLY103A, GLY103H, GLY110A, GLY110H, GLY114A, GLY114H, GLY120A, GLY120H, GLY167A, GLY167H, GLY260A, GLY260H, GLY262A, GLY262H, GLY295A, GLY295H, GLY319A, GLY319H, GLY321A, GLY321H, GLY325A, GLY325H, GLY368A, GLY368H, GLY369A, GLY369H, GLY36A, GLY373A, GLY373H, GLY391A, GLY391H, GLY392A, GLY392H, GLY393A, GLY393H, GLY396A, GLY396H, GLY400A, GLY400H, GLY439A, GLY53A, GLY53H, HIS281A, HIS281H, HIS285A, HIS285H, HIS294A, HIS294H, HIS314A, HIS314H, HIS371A, HIS371H, HIS397A, HIS397H, HIS94A, HIS94H, ILE108A, ILE108H, ILE112A, ILE112H, ILE230A, ILE230H, ILE258A, ILE258H, ILE267A, ILE267H, ILE296A, ILE296H, ILE308A, ILE308H, ILE8H, LEU101A, LEU101H, LEU104A, LEU104H, LEU105A, LEU105H, LEU121A, LEU121H, LEU123A, LEU123H, LEU126A, LEU176A, LEU176H, LEU180A, LEU180H, LEU194A, LEU194H, LEU234A, LEU234H, LEU235A, LEU235H, LEU264A, LEU264H, LEU270A, LEU270H, LEU301A, LEU301H, LEU304A, LEU304H, LEU323A, LEU323H, LEU370A, LEU370H, LEU390A, LEU390H, LEU395A, LEU395H, LEU58A, LEU58H, LEU70A, LEU70H, LYS116A, LYS116H, LYS119A, LYS119H, LYS131A, LYS163A, LYS163H, LYS165A, LYS165H, LYS175A, LYS175H, LYS322A, LYS322H, LYS437A, LYS437H, MET115A, MET115H, MET188A, MET188H, MET237A, MET237H, MET253A, MET253H, MET284A, MET284H, PHE113A, PHE113H, PHE136A, PHE136H, PHE173A, PHE173H, PHE202A, PHE202H, PHE288A, PHE288H, PHE93A, PHE93H, PHE96A, PHE96H, PRO102A, PRO102H, PRO162A, PRO162H, PRO164A, PRO164H, PRO170A, PRO170H, PRO197A, PRO197H, PRO372A, PRO372H, PRO398A, PRO398H, PRO401A, PRO401H, PRO443A, PRO443H, PRO60A, PRO60H, PRO92A, PRO92H, SER107A, SER107H, SER169A, SER169H, SER196A, SER196H, SER367A, SER367H, SER50A, SER50H, SER51A, SER51H, SER71A, SER71H, THR195A, THR195H, THR231A, THR231H, THR259A, THR259H, THR289A, THR289H, THR317A, THR317H, THR32H, THR394A, THR394H, THR442A, THR442H, THR52A, THR52H, THR54A, THR54H, THR56A, THR56H, THR57A, THR57H, THR7H, TRP198A, TRP198H, TRP261A, TRP261H, TRP438A, TRP438H, TRP55A, TRP55H, TRP61A, TRP61H, TRP67A, TRP67H, TYR12A, TYR12H, TYR168A, TYR168H, TYR199A, TYR199H, TYR266A, TYR266H, TYR293A, TYR293H, TYR37A, TYR37H, TYR59A, TYR59H, TYR62A, TYR62H, TYR91H, TYR9A, TYR9H, VAL118A, VAL118H, VAL161A, VAL161H, VAL166A, VAL166H, VAL254A, VAL254H, VAL256A, VAL256H, VAL257A, VAL257H, VAL300A, VAL300H, VAL441A, VAL441H, VAL444A, VAL444H, VAL46A
• B-C: ALA99B, ARG134B, ARG201C, ARG23B, ASN200C, ASP137B, GLU130B, GLU135B, GLU171C, GLU172C, GLU204C, GLU98B, GLY167C, ILE133B, ILE208C, ILE359B, LEU132B, LYS131B, LYS22B, LYS355B, PHE173C, PHE93B, PRO129B, PRO170C, PRO197C, SER169C, SER358B, TRP198C, TYR168C, TYR199C, TYR357B
• B-F: ALA68B, ALA68F, ALA72B, ALA95B, ALA95F, ARG134B, ARG134F, ARG23B, ARG23F, ARG66B, ARG66F, ASP24B, ASP24F, ASP69B, ASP69F, GLN64B, GLN64F, GLU130B, GLU130F, GLU63B, GLU63F, GLU65B, GLU65F, GLU97B, GLU98B, GLU98F, HIS341B, HIS94B, HIS94F, LEU70B, LEU70F, LYS131B, LYS131F, LYS21B, LYS21F, LYS22B, LYS22F, LYS355B, LYS355F, PHE93B, PHE93F, PHE96B, PHE96F, PRO129F, PRO19B, PRO19F, PRO92B, PRO92F, SER20B, SER20F, SER71B, SER71F, TRP67B, TRP67F, TYR127B, TYR127F, TYR17B, TYR17F, TYR357B, TYR357F, TYR62F, TYR91B, TYR91F
• B-G: ALA106B, ALA106G, ALA109B, ALA109G, ALA177B, ALA177G, ALA232B, ALA232G, ALA263B, ALA263G, ALA283B, ALA283G, ALA286B, ALA286G, ALA287B, ALA287G, ALA318B, ALA318G, ALA320B, ALA320G, ALA34B, ALA34G, ALA402B, ALA402G, ALA42B, ALA42G, ALA45B, ALA45G, ALA47B, ALA47G, ALA48B, ALA48G, ALA68B, ALA68G, ALA95B, ALA95G, ALA99B, ALA99G, ARG117B, ARG117G, ARG122B, ARG122G, ARG201B, ARG201G, ARG240B, ARG240G, ARG265B, ARG265G, ARG282B, ARG282G, ARG290B, ARG290G, ARG327G, ARG66B, ARG66G, ASN100B, ASN100G, ASN111B, ASN111G, ASN193B, ASN193G, ASN200B, ASN200G, ASN229B, ASN229G, ASN291B, ASN291G, ASN374B, ASN374G, ASP179B, ASP179G, ASP191B, ASP191G, ASP233B, ASP233G, ASP255B, ASP255G, ASP269B, ASP269G, ASP399B, ASP399G, ASP69B, ASP69G, GLN389B, GLN389G, GLN41B, GLN41G, GLN64B, GLN64G, GLU171B, GLU171G, GLU172B, GLU172G, GLU174B, GLU174G, GLU192B, GLU192G, GLU236B, GLU236G, GLU238B, GLU238G, GLU324B, GLU324G, GLU326B, GLU326G, GLU35B, GLU35G, GLU49B, GLU49G, GLU63B, GLU63G, GLU65B, GLU65G, GLU97B, GLU97G, GLU98B, GLU98G, GLY103B, GLY103G, GLY110B, GLY110G, GLY114B, GLY114G, GLY120B, GLY120G, GLY167B, GLY167G, GLY260B, GLY260G, GLY262B, GLY262G, GLY295B, GLY295G, GLY319B, GLY319G, GLY321B, GLY321G, GLY325B, GLY325G, GLY368B, GLY368G, GLY369B, GLY369G, GLY373B, GLY373G, GLY391B, GLY391G, GLY392B, GLY392G, GLY393B, GLY393G, GLY396B, GLY396G, GLY400B, GLY400G, GLY439B, GLY53B, GLY53G, HIS281B, HIS281G, HIS285B, HIS285G, HIS294B, HIS294G, HIS314B, HIS314G, HIS371B, HIS371G, HIS397B, HIS397G, HIS94B, HIS94G, ILE108B, ILE108G, ILE112B, ILE112G, ILE230B, ILE230G, ILE258B, ILE258G, ILE267B, ILE267G, ILE296B, ILE296G, ILE308B, ILE308G, LEU101B, LEU101G, LEU104B, LEU104G, LEU105B, LEU105G, LEU121B, LEU121G, LEU123B, LEU123G, LEU126G, LEU176B, LEU176G, LEU180B, LEU180G, LEU194B, LEU194G, LEU234B, LEU234G, LEU235B, LEU235G, LEU264B, LEU264G, LEU270B, LEU270G, LEU301B, LEU301G, LEU304B, LEU304G, LEU323B, LEU323G, LEU370B, LEU370G, LEU390B, LEU390G, LEU395B, LEU395G, LEU58B, LEU58G, LEU70B, LEU70G, LYS116B, LYS116G, LYS119B, LYS119G, LYS163B, LYS163G, LYS165B, LYS165G, LYS175B, LYS175G, LYS322B, LYS322G, LYS437B, LYS437G, MET115B, MET115G, MET188B, MET188G, MET237B, MET237G, MET253B, MET253G, MET284B, MET284G, PHE113B, PHE113G, PHE136B, PHE136G, PHE173B, PHE173G, PHE202B, PHE202G, PHE288B, PHE288G, PHE93B, PHE93G, PHE96B, PHE96G, PRO102B, PRO102G, PRO162B, PRO162G, PRO164B, PRO164G, PRO170B, PRO170G, PRO197B, PRO197G, PRO292B, PRO292G, PRO372B, PRO372G, PRO398B, PRO398G, PRO401B, PRO401G, PRO443B, PRO443G, PRO60B, PRO60G, PRO92B, PRO92G, SER107B, SER107G, SER169B, SER169G, SER196B, SER196G, SER367B, SER367G, SER50B, SER50G, SER51B, SER51G, SER71B, SER71G, THR195B, THR195G, THR231B, THR231G, THR259B, THR259G, THR289B, THR289G, THR317B, THR317G, THR32B, THR32G, THR394B, THR394G, THR442B, THR442G, THR52B, THR52G, THR54B, THR54G, THR56B, THR56G, THR57B, THR57G, THR7B, TRP198B, TRP198G, TRP261B, TRP261G, TRP438B, TRP438G, TRP55B, TRP55G, TRP61B, TRP61G, TRP67B, TRP67G, TYR12B, TYR12G, TYR168B, TYR168G, TYR199B, TYR199G, TYR266B, TYR266G, TYR293B, TYR293G, TYR37B, TYR37G, TYR59B, TYR59G, TYR62B, TYR62G, TYR91B, TYR91G, TYR9B, TYR9G, VAL118B, VAL118G, VAL161B, VAL161G, VAL166B, VAL166G, VAL254B, VAL254G, VAL256B, VAL256G, VAL257B, VAL257G, VAL300B, VAL300G, VAL441B, VAL441G, VAL444B, VAL444G, VAL46B
• C-D: ARG134C, ARG201D, ARG23C, ASN200D, GLU130C, GLU135C, GLU171D, GLU172D, GLU204D, GLU98C, GLY167D, ILE133C, ILE208D, ILE359C, LEU132C, LYS131C, LYS22C, LYS355C, PHE173D, PHE356C, PHE93C, PRO129C, PRO170D, PRO197D, SER169D, SER358C, TRP198D, TYR168D, TYR199D, TYR357C
• C-F: ALA106C, ALA106F, ALA109C, ALA109F, ALA177C, ALA177F, ALA232C, ALA232F, ALA263C, ALA263F, ALA283C, ALA283F, ALA286C, ALA286F, ALA287C, ALA287F, ALA318C, ALA318F, ALA320C, ALA320F, ALA34C, ALA34F, ALA402C, ALA402F, ALA42C, ALA42F, ALA45C, ALA45F, ALA47C, ALA47F, ALA48C, ALA48F, ALA68C, ALA68F, ALA72F, ALA95C, ALA95F, ALA99C, ALA99F, ARG117C, ARG117F, ARG122C, ARG122F, ARG201C, ARG201F, ARG240C, ARG240F, ARG265C, ARG265F, ARG282C, ARG282F, ARG290C, ARG290F, ARG327F, ARG66C, ARG66F, ASN100C, ASN100F, ASN111C, ASN111F, ASN193C, ASN193F, ASN200C, ASN200F, ASN229C, ASN229F, ASN291C, ASN291F, ASN374C, ASN374F, ASP179C, ASP179F, ASP191C, ASP191F, ASP233C, ASP233F, ASP255C, ASP255F, ASP269C, ASP269F, ASP399C, ASP399F, ASP69C, ASP69F, ASP6C, GLN389C, GLN389F, GLN41C, GLN41F, GLN64C, GLN64F, GLU171C, GLU171F, GLU172C, GLU172F, GLU174C, GLU174F, GLU192C, GLU192F, GLU236C, GLU236F, GLU238C, GLU238F, GLU324C, GLU324F, GLU326C, GLU326F, GLU35C, GLU35F, GLU49C, GLU49F, GLU63C, GLU63F, GLU65C, GLU65F, GLU97C, GLU97F, GLU98C, GLU98F, GLY103C, GLY103F, GLY110C, GLY110F, GLY114C, GLY114F, GLY120C, GLY120F, GLY167C, GLY167F, GLY260C, GLY260F, GLY262C, GLY262F, GLY295C, GLY295F, GLY319C, GLY319F, GLY321C, GLY321F, GLY325C, GLY325F, GLY368C, GLY368F, GLY369C, GLY369F, GLY373C, GLY373F, GLY391C, GLY391F, GLY392C, GLY392F, GLY393C, GLY393F, GLY396C, GLY396F, GLY400C, GLY400F, GLY53C, GLY53F, HIS281C, HIS281F, HIS285C, HIS285F, HIS294C, HIS294F, HIS314C, HIS314F, HIS371C, HIS371F, HIS397C, HIS397F, HIS94C, HIS94F, ILE108C, ILE108F, ILE112C, ILE112F, ILE230C, ILE230F, ILE258C, ILE258F, ILE267C, ILE267F, ILE296C, ILE296F, ILE308C, ILE308F, LEU101C, LEU101F, LEU104C, LEU104F, LEU105C, LEU105F, LEU121C, LEU121F, LEU123C, LEU123F, LEU126F, LEU176C, LEU176F, LEU180C, LEU180F, LEU194C, LEU194F, LEU234C, LEU234F, LEU235C, LEU235F, LEU264C, LEU264F, LEU270C, LEU270F, LEU301C, LEU301F, LEU304C, LEU304F, LEU323C, LEU323F, LEU370C, LEU370F, LEU390C, LEU390F, LEU395C, LEU395F, LEU58C, LEU58F, LEU70C, LEU70F, LYS116C, LYS116F, LYS119C, LYS119F, LYS163C, LYS163F, LYS165C, LYS165F, LYS175C, LYS175F, LYS322C, LYS322F, LYS437C, LYS437F, MET115C, MET115F, MET188C, MET188F, MET237C, MET237F, MET253C, MET253F, MET284C, MET284F, PHE113C, PHE113F, PHE136C, PHE136F, PHE173C, PHE173F, PHE202C, PHE202F, PHE288C, PHE288F, PHE5C, PHE93C, PHE93F, PHE96C, PHE96F, PRO102C, PRO102F, PRO162C, PRO162F, PRO164C, PRO164F, PRO170C, PRO170F, PRO197C, PRO197F, PRO372C, PRO372F, PRO398C, PRO398F, PRO401C, PRO401F, PRO443C, PRO443F, PRO60C, PRO60F, PRO92C, PRO92F, SER107C, SER107F, SER169C, SER169F, SER196C, SER196F, SER367C, SER367F, SER50C, SER50F, SER51C, SER51F, SER71C, SER71F, THR195C, THR195F, THR231C, THR231F, THR259C, THR259F, THR289C, THR289F, THR317C, THR317F, THR32C, THR32F, THR394C, THR394F, THR442C, THR442F, THR52C, THR52F, THR54C, THR54F, THR56C, THR56F, THR57C, THR57F, TRP198C, TRP198F, TRP261C, TRP261F, TRP438C, TRP438F, TRP55C, TRP55F, TRP61C, TRP61F, TRP67C, TRP67F, TYR12C, TYR12F, TYR168C, TYR168F, TYR199C, TYR199F, TYR266C, TYR266F, TYR293C, TYR293F, TYR37C, TYR37F, TYR59C, TYR59F, TYR62C, TYR62F, TYR91C, TYR91F, TYR9C, TYR9F, VAL118C, VAL118F, VAL160F, VAL161C, VAL161F, VAL166C, VAL166F, VAL254C, VAL254F, VAL256C, VAL256F, VAL257C, VAL257F, VAL300C, VAL300F, VAL441C, VAL441F, VAL444C, VAL444F, VAL46F
• C-J: ALA68C, ALA68J, ALA72C, ALA72J, ALA95C, ALA95J, ARG134C, ARG134J, ARG23C, ARG23J, ARG66C, ARG66J, ASP24C, ASP24J, ASP69C, ASP69J, GLN64C, GLN64J, GLU130C, GLU130J, GLU63C, GLU63J, GLU65C, GLU65J, GLU97C, GLU98C, GLU98J, HIS341C, HIS341J, HIS94C, HIS94J, LEU70C, LEU70J, LYS131C, LYS131J, LYS21C, LYS21J, LYS22C, LYS22J, LYS355C, LYS355J, LYS73C, LYS73J, PHE93C, PHE93J, PHE96C, PHE96J, PRO129C, PRO129J, PRO92C, PRO92J, SER20C, SER20J, SER71C, SER71J, TRP67C, TRP67J, TYR17C, TYR17J, TYR357C, TYR357J, TYR62C, TYR62J, TYR91C, TYR91J
• D-E: ALA99D, ARG134D, ARG201E, ARG23D, ASN200E, ASP137D, GLU130D, GLU135D, GLU171E, GLU172E, GLU204E, GLU98D, GLY167E, ILE133D, ILE208E, ILE359D, LEU132D, LYS131D, LYS22D, LYS355D, PHE136D, PHE173E, PHE93D, PRO129D, PRO170E, PRO197E, SER169E, SER358D, TRP198E, TYR168E, TYR199E, TYR357D
• D-I: ALA68D, ALA68I, ALA72I, ALA95D, ALA95I, ARG134D, ARG134I, ARG23D, ARG23I, ARG66D, ARG66I, ASP24D, ASP24I, ASP69D, ASP69I, GLN64D, GLN64I, GLU130D, GLU130I, GLU135D, GLU135I, GLU63D, GLU63I, GLU65D, GLU65I, GLU97D, GLU97I, GLU98D, GLU98I, HIS341D, HIS94D, HIS94I, LEU70D, LEU70I, LYS131D, LYS131I, LYS21D, LYS21I, LYS22D, LYS22I, LYS355D, LYS355I, LYS73D, LYS73I, PHE93D, PHE93I, PHE96D, PHE96I, PRO92D, PRO92I, SER20D, SER20I, SER71D, SER71I, TRP67D, TRP67I, TYR17D, TYR17I, TYR357D, TYR357I, TYR62D, TYR62I, TYR91D, TYR91I
• D-J: ALA106D, ALA106J, ALA109D, ALA109J, ALA177D, ALA177J, ALA232D, ALA232J, ALA263D, ALA263J, ALA283D, ALA283J, ALA286D, ALA286J, ALA287D, ALA287J, ALA318D, ALA318J, ALA320D, ALA320J, ALA34D, ALA34J, ALA402D, ALA42D, ALA42J, ALA434D, ALA45D, ALA45J, ALA47D, ALA47J, ALA48D, ALA48J, ALA68D, ALA68J, ALA95D, ALA95J, ALA99D, ALA99J, ARG117D, ARG117J, ARG122D, ARG122J, ARG201D, ARG201J, ARG240D, ARG240J, ARG265D, ARG265J, ARG282D, ARG282J, ARG290D, ARG290J, ARG327D, ARG66D, ARG66J, ASN100D, ASN100J, ASN111D, ASN111J, ASN193D, ASN193J, ASN200D, ASN200J, ASN229D, ASN229J, ASN291D, ASN291J, ASN374D, ASN374J, ASP191D, ASP191J, ASP233D, ASP233J, ASP255D, ASP255J, ASP269D, ASP269J, ASP399D, ASP399J, ASP69D, ASP69J, GLN389D, GLN389J, GLN41D, GLN41J, GLN64D, GLN64J, GLU171D, GLU171J, GLU172D, GLU172J, GLU174D, GLU174J, GLU192D, GLU192J, GLU236D, GLU236J, GLU238D, GLU238J, GLU324D, GLU324J, GLU326D, GLU326J, GLU35D, GLU35J, GLU49D, GLU49J, GLU63D, GLU63J, GLU65D, GLU65J, GLU97D, GLU97J, GLU98D, GLU98J, GLY103D, GLY103J, GLY110D, GLY110J, GLY114D, GLY114J, GLY120D, GLY120J, GLY167D, GLY167J, GLY260D, GLY260J, GLY262D, GLY262J, GLY295D, GLY295J, GLY319D, GLY319J, GLY321D, GLY321J, GLY325D, GLY325J, GLY368D, GLY368J, GLY369D, GLY369J, GLY373D, GLY373J, GLY391D, GLY391J, GLY392D, GLY392J, GLY393D, GLY393J, GLY396D, GLY396J, GLY400D, GLY400J, GLY53D, GLY53J, HIS281D, HIS281J, HIS285D, HIS285J, HIS294D, HIS294J, HIS314D, HIS314J, HIS371D, HIS371J, HIS397D, HIS397J, HIS94D, HIS94J, ILE108D, ILE108J, ILE112D, ILE112J, ILE230D, ILE230J, ILE258D, ILE258J, ILE267D, ILE267J, ILE296D, ILE296J, ILE308D, ILE308J, LEU101D, LEU101J, LEU104D, LEU104J, LEU105D, LEU105J, LEU121D, LEU121J, LEU123D, LEU123J, LEU176D, LEU176J, LEU180D, LEU180J, LEU194D, LEU194J, LEU234D, LEU234J, LEU235D, LEU235J, LEU264D, LEU264J, LEU270D, LEU270J, LEU301D, LEU301J, LEU304D, LEU304J, LEU323D, LEU323J, LEU370D, LEU370J, LEU390D, LEU390J, LEU395D, LEU395J, LEU58D, LEU58J, LEU70D, LEU70J, LYS116D, LYS116J, LYS119D, LYS119J, LYS163D, LYS163J, LYS165D, LYS165J, LYS175D, LYS175J, LYS322D, LYS322J, LYS437D, LYS437J, MET115D, MET115J, MET188D, MET188J, MET237D, MET237J, MET253D, MET253J, MET284D, MET284J, PHE113D, PHE113J, PHE136D, PHE136J, PHE173D, PHE173J, PHE202D, PHE202J, PHE288D, PHE288J, PHE93D, PHE93J, PHE96D, PHE96J, PRO102D, PRO102J, PRO162D, PRO162J, PRO164D, PRO164J, PRO170D, PRO170J, PRO197D, PRO197J, PRO292D, PRO292J, PRO372D, PRO372J, PRO398D, PRO398J, PRO401D, PRO401J, PRO443D, PRO443J, PRO60D, PRO60J, PRO92D, PRO92J, SER107D, SER107J, SER169D, SER169J, SER196D, SER196J, SER367D, SER367J, SER50D, SER50J, SER51D, SER51J, SER71D, SER71J, THR195D, THR195J, THR231D, THR231J, THR259D, THR259J, THR289D, THR289J, THR317D, THR317J, THR32D, THR32J, THR394D, THR394J, THR442D, THR442J, THR52D, THR52J, THR54D, THR54J, THR56D, THR56J, THR57D, THR57J, TRP198D, TRP198J, TRP261D, TRP261J, TRP438D, TRP438J, TRP55D, TRP55J, TRP61D, TRP61J, TRP67D, TRP67J, TYR12D, TYR12J, TYR168D, TYR168J, TYR199D, TYR199J, TYR266D, TYR266J, TYR293D, TYR293J, TYR37D, TYR37J, TYR59D, TYR59J, TYR62D, TYR62J, TYR91D, TYR91J, TYR9D, TYR9J, VAL118D, VAL118J, VAL160D, VAL161D, VAL161J, VAL166D, VAL166J, VAL254D, VAL254J, VAL256D, VAL256J, VAL257D, VAL257J, VAL300D, VAL300J, VAL441D, VAL441J, VAL444D, VAL444J, VAL46D
• E-H: ALA68E, ALA68H, ALA72E, ALA72H, ALA95E, ALA95H, ARG134E, ARG134H, ARG23E, ARG23H, ARG66E, ARG66H, ASP24E, ASP24H, ASP69E, ASP69H, GLN64E, GLN64H, GLU130E, GLU130H, GLU63E, GLU63H, GLU65E, GLU65H, GLU98E, GLU98H, HIS341E, HIS341H, HIS94E, HIS94H, LEU70E, LEU70H, LYS131E, LYS131H, LYS21E, LYS21H, LYS22E, LYS22H, LYS355E, LYS355H, LYS73E, LYS73H, PHE93E, PHE93H, PHE96E, PRO92E, PRO92H, SER20E, SER20H, SER71E, SER71H, TRP67E, TRP67H, TYR17E, TYR17H, TYR357E, TYR357H, TYR62H, TYR91E, TYR91H
• E-I: ALA106E, ALA106I, ALA109E, ALA109I, ALA177E, ALA177I, ALA232E, ALA232I, ALA263E, ALA263I, ALA283E, ALA283I, ALA286E, ALA286I, ALA287E, ALA287I, ALA318E, ALA318I, ALA320E, ALA320I, ALA34E, ALA34I, ALA402E, ALA402I, ALA403I, ALA42E, ALA434I, ALA45E, ALA45I, ALA47E, ALA47I, ALA48E, ALA48I, ALA68E, ALA68I, ALA95E, ALA95I, ALA99E, ALA99I, ARG117E, ARG117I, ARG122E, ARG122I, ARG201E, ARG201I, ARG240E, ARG240I, ARG265E, ARG265I, ARG282E, ARG282I, ARG290E, ARG290I, ARG327E, ARG433I, ARG66E, ARG66I, ASN100E, ASN100I, ASN111E, ASN111I, ASN193E, ASN193I, ASN200E, ASN200I, ASN229E, ASN229I, ASN291E, ASN291I, ASN374E, ASN374I, ASP191E, ASP191I, ASP233E, ASP233I, ASP255E, ASP255I, ASP269E, ASP269I, ASP399E, ASP399I, ASP69E, ASP69I, ASP6E, GLN239E, GLN239I, GLN389E, GLN389I, GLN41E, GLN41I, GLN64E, GLN64I, GLU171E, GLU171I, GLU172E, GLU172I, GLU174E, GLU174I, GLU192E, GLU192I, GLU236E, GLU236I, GLU238E, GLU238I, GLU324E, GLU324I, GLU326E, GLU326I, GLU35E, GLU35I, GLU49E, GLU49I, GLU63E, GLU63I, GLU65E, GLU65I, GLU97E, GLU97I, GLU98E, GLU98I, GLY103E, GLY103I, GLY110E, GLY110I, GLY114E, GLY114I, GLY120E, GLY120I, GLY167E, GLY167I, GLY260E, GLY260I, GLY262E, GLY262I, GLY295E, GLY295I, GLY319E, GLY319I, GLY321E, GLY321I, GLY325E, GLY325I, GLY368E, GLY368I, GLY369E, GLY369I, GLY36I, GLY373E, GLY373I, GLY391E, GLY391I, GLY392E, GLY392I, GLY393E, GLY393I, GLY396E, GLY396I, GLY400E, GLY400I, GLY404I, GLY439I, GLY53E, GLY53I, HIS281E, HIS281I, HIS285E, HIS285I, HIS294E, HIS294I, HIS314E, HIS314I, HIS371E, HIS371I, HIS397E, HIS397I, HIS94E, HIS94I, ILE108E, ILE108I, ILE112E, ILE112I, ILE230E, ILE230I, ILE258E, ILE258I, ILE267E, ILE267I, ILE296E, ILE296I, ILE308E, ILE308I, ILE8E, LEU101E, LEU101I, LEU104E, LEU104I, LEU105E, LEU105I, LEU121E, LEU121I, LEU123E, LEU123I, LEU176E, LEU176I, LEU180E, LEU180I, LEU194E, LEU194I, LEU234E, LEU234I, LEU235E, LEU235I, LEU264E, LEU264I, LEU270E, LEU270I, LEU301E, LEU301I, LEU304E, LEU304I, LEU323E, LEU323I, LEU370E, LEU370I, LEU390E, LEU390I, LEU395E, LEU395I, LEU58E, LEU58I, LEU70E, LEU70I, LYS116E, LYS116I, LYS119E, LYS119I, LYS163E, LYS163I, LYS165E, LYS165I, LYS175E, LYS175I, LYS322E, LYS322I, LYS437E, LYS437I, MET115E, MET115I, MET188E, MET188I, MET237E, MET237I, MET253E, MET253I, MET284E, MET284I, PHE113E, PHE113I, PHE136E, PHE136I, PHE173E, PHE173I, PHE202E, PHE202I, PHE288E, PHE288I, PHE5E, PHE93E, PHE93I, PHE96E, PHE96I, PRO102E, PRO102I, PRO162E, PRO162I, PRO164E, PRO164I, PRO170E, PRO170I, PRO197E, PRO197I, PRO292I, PRO372E, PRO372I, PRO398E, PRO398I, PRO401E, PRO401I, PRO443E, PRO443I, PRO60E, PRO60I, PRO92E, PRO92I, SER107E, SER107I, SER169E, SER169I, SER196E, SER196I, SER367E, SER367I, SER50E, SER50I, SER51E, SER51I, SER71E, SER71I, THR195E, THR195I, THR231E, THR231I, THR259E, THR259I, THR289E, THR289I, THR317E, THR317I, THR32E, THR32I, THR394E, THR394I, THR442E, THR442I, THR52E, THR52I, THR54E, THR54I, THR56E, THR56I, THR57E, THR57I, TRP198E, TRP198I, TRP261E, TRP261I, TRP438E, TRP438I, TRP55E, TRP55I, TRP61E, TRP61I, TRP67E, TRP67I, TYR12E, TYR12I, TYR168E, TYR168I, TYR199E, TYR199I, TYR266E, TYR266I, TYR293E, TYR293I, TYR37E, TYR37I, TYR59E, TYR59I, TYR62E, TYR62I, TYR91E, TYR9E, TYR9I, VAL118E, VAL118I, VAL160I, VAL161E, VAL161I, VAL166E, VAL166I, VAL254E, VAL254I, VAL256E, VAL256I, VAL257E, VAL257I, VAL300E, VAL300I, VAL441E, VAL441I, VAL444E, VAL444I, VAL46I
• F-G: ALA99F, ARG134F, ARG201G, ARG23F, ASN200G, ASP137F, GLU130F, GLU135F, GLU171G, GLU172G, GLU204G, GLU98F, GLY167G, ILE133F, ILE208G, ILE359F, LEU132F, LYS131F, LYS22F, LYS355F, PHE173G, PHE93F, PRO129F, PRO170G, PRO197G, SER169G, SER358F, TRP198G, TYR168G, TYR199G, TYR357F
• F-J: ARG134J, ARG201F, ARG23J, ASN200F, ASP137J, GLU130J, GLU135J, GLU171F, GLU172F, GLU204F, GLU98J, GLY167F, ILE133J, ILE208F, ILE359J, LEU132J, LYS131J, LYS22J, LYS355J, PHE173F, PHE93J, PRO129J, PRO170F, PRO197F, SER169F, SER358J, TRP198F, TYR168F, TYR199F, TYR357J
• G-H: ARG134G, ARG201H, ARG23G, ASN200H, ASP137G, GLU130G, GLU135G, GLU171H, GLU172H, GLU204H, GLU98G, GLY167H, ILE133G, ILE208H, ILE359G, LEU132G, LYS131G, LYS22G, LYS355G, PHE136G, PHE173H, PHE93G, PRO129G, PRO170H, PRO197H, SER169H, SER358G, TRP198H, TYR168H, TYR199H, TYR357G
• H-I: ALA99H, ARG134H, ARG201I, ARG23H, ASN200I, ASP137H, GLU130H, GLU135H, GLU171I, GLU172I, GLU204I, GLU98H, GLY167I, ILE133H, ILE208I, ILE359H, LEU132H, LYS131H, LYS22H, LYS355H, PHE173I, PHE93H, PRO129H, PRO170I, PRO197I, SER169I, SER358H, TRP198I, TYR168I, TYR199I, TYR357H
• I-J: ALA99I, ARG134I, ARG201J, ARG23I, ASN200J, ASP137I, GLU130I, GLU135I, GLU171J, GLU172J, GLU204J, GLU98I, GLY167J, ILE133I, ILE208J, ILE359I, LEU132I, LYS131I, LYS22I, LYS355I, PHE136I, PHE173J, PHE93I, PRO129I, PRO170J, PRO197J, SER169J, SER358I, TRP198J, TYR168J, TYR199J, TYR357I