3KCV

structure of formate channel

• Total interactions analyzed: 45
• Total true interactions: 30
• Strongest Interaction:
  • Chains: F-J
  • Int. Res.: 156
  • Norm. En. per Res.: -2.9981
• Hub Node: A(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-22.126	11.832	-404.453	-414.7471	157	35	16	17997	0	10	8
A-C	0.0	0.0	-2.2454	-2.2454	7	1	0	86	0	1	2
A-D	0.0	0.0	-0.2131	-0.2131	3	0	0	50	0	2	2
A-E	-26.7727	12.4074	-435.804	-450.1693	158	37	15	19070	0	10	10
A-F	-5.5656	9.9712	-30.8109	-26.4053	35	8	0	1757	0	5	6
A-G	-3.664	-2.6855	-78.3182	-84.6677	42	3	1	3276	0	4	2
A-J	0.0	0.0	-0.1432	-0.1432	6	0	0	29	0	0	0
B-C	-30.3436	9.4994	-401.336	-422.1802	153	30	13	17502	0	11	7
B-D	0.0	0.0	-0.2643	-0.2643	5	0	0	63	0	1	2
B-E	0.0	0.0	-0.1075	-0.1075	7	0	0	55	0	1	2
B-G	0.0	-10.9416	-7.7195	-18.6611	22	3	0	817	0	7	5
C-D	-23.1998	11.7077	-389.724	-401.2161	155	34	14	17500	0	10	8
C-E	0.0	0.0	-0.7141	-0.7141	7	0	0	103	0	1	2
C-G	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	2
D-E	-31.7427	8.9618	-394.43	-417.2109	151	46	13	17657	0	12	11
D-H	-18.38	-16.3986	-27.9638	-62.7424	30	11	0	1400	0	6	4
E-F	0.0	0.0	-1.2686	-1.2686	4	0	0	86	0	0	0
E-H	0.0	0.0	-14.382	-14.382	24	1	0	735	0	4	1
E-I	-10.3275	0.0	-39.2331	-49.5606	35	3	0	1749	0	3	0
E-J	0.0	0.0	-9.0715	-9.0715	12	2	0	376	0	0	0
F-G	-27.5882	18.215	-398.834	-408.2073	155	33	15	18179	0	13	11
F-H	0.0	0.0	-0.796	-0.796	8	0	0	141	0	2	2
F-I	0.0	0.0	-0.6199	-0.6199	6	0	0	125	0	1	2
F-J	-44.9334	20.0021	-442.769	-467.7004	156	43	15	19858	0	11	11
G-H	-35.0627	8.8032	-344.634	-370.8935	151	29	11	16542	0	11	11
G-I	0.0	0.0	-0.4309	-0.4309	8	0	0	90	0	1	2
G-J	0.0	0.0	-0.183	-0.183	9	0	0	76	0	2	2
H-I	-39.3897	13.8667	-411.528	-437.051	156	40	17	18917	0	11	11
H-J	0.0	0.0	-0.2945	-0.2945	6	0	0	79	0	2	2
I-J	-20.7228	8.0698	-428.375	-441.0281	158	41	14	18761	0	10	10

Interface residues

• A-B: ALA141B, ALA164A, ALA171A, ALA178A, ALA192A, ALA192B, ALA200A, ALA204A, ALA38B, ALA41B, ALA48B, ALA55B, ALA67A, ALA67B, ALA87B, ARG186A, ARG186B, ASN142B, ASN148B, ASP190A, ASP190B, CYS166A, CYS176A, CYS74B, CYS82B, CYS85B, GLN144B, GLU137B, GLU163A, GLU208A, GLY136B, GLY168A, GLY185A, GLY206A, GLY265A, GLY271A, GLY58B, GLY60B, GLY65A, GLY71B, GLY72A, GLY72B, GLY78B, GLY86B, HIS155A, HIS159A, HIS30B, ILE162A, ILE169A, ILE194A, ILE264A, ILE277A, ILE39B, ILE47B, ILE53B, ILE73A, ILE73B, ILE80B, LEU127B, LEU130B, LEU131B, LEU134B, LEU167A, LEU170A, LEU173A, LEU177A, LEU188A, LEU188B, LEU197A, LEU268A, LEU269A, LEU272A, LEU279A, LEU32B, LEU37B, LEU69A, LEU69B, LEU77B, LEU79B, LEU81B, LEU95A, LYS191A, LYS191B, LYS33B, LYS68A, LYS68B, MET132B, MET139B, MET174A, MET181A, MET189A, MET189B, MET195A, MET195B, MET201A, MET62A, MET62B, MET66A, MET66B, PHE128B, PHE193A, PHE193B, PHE202A, PHE207A, PHE215B, PHE35B, PHE44B, PHE49B, PHE51B, PHE64A, PHE75B, PRO198A, PRO31B, PRO63A, PRO63B, SER135B, SER182A, SER184A, SER187A, SER187B, SER205A, SER46B, SER76B, THR140B, THR160A, THR273A, THR34B, THR40B, THR54B, THR56B, THR57B, THR59B, THR61A, THR61B, TRP133B, TRP145B, TRP180A, TRP275A, TYR138B, TYR183A, TYR274A, TYR278A, TYR36B, TYR52B, VAL165A, VAL179A, VAL196A, VAL196B, VAL199A, VAL203A, VAL276A, VAL43B, VAL50B, VAL70A, VAL70B, VAL83B, VAL84B
• A-C: ASP190A, MET189A, MET189C, PHE193A, PHE193C, SER187A, SER187C
• A-D: MET189A, MET189D, PHE193D
• A-E: ALA141A, ALA164E, ALA171E, ALA178E, ALA192A, ALA192E, ALA200E, ALA204E, ALA38A, ALA41A, ALA48A, ALA55A, ALA67A, ALA67E, ALA87A, ARG186A, ARG186E, ARG280E, ASN142A, ASN148A, ASP190A, ASP190E, CYS166E, CYS74A, CYS82A, CYS85A, GLN144A, GLU137A, GLU163E, GLU208E, GLY136A, GLY168E, GLY185A, GLY185E, GLY206E, GLY261E, GLY265E, GLY58A, GLY60A, GLY60E, GLY65A, GLY65E, GLY71A, GLY72A, GLY72E, GLY78A, GLY86A, HIS155E, HIS159E, HIS30A, ILE162E, ILE169E, ILE194E, ILE264E, ILE277E, ILE39A, ILE47A, ILE53A, ILE73A, ILE73E, ILE80A, LEU127A, LEU130A, LEU131A, LEU134A, LEU167E, LEU170E, LEU173E, LEU177E, LEU188A, LEU188E, LEU197E, LEU268E, LEU269E, LEU272E, LEU279E, LEU32A, LEU37A, LEU69A, LEU69E, LEU77A, LEU79A, LEU81A, LEU95E, LYS191A, LYS191E, LYS33A, LYS68A, LYS68E, MET132A, MET139A, MET174E, MET181E, MET189A, MET189E, MET195A, MET195E, MET201E, MET62A, MET62E, MET66A, MET66E, PHE128A, PHE161E, PHE193A, PHE193E, PHE202E, PHE207E, PHE35A, PHE44A, PHE49A, PHE51A, PHE64E, PHE75A, PRO198E, PRO31A, PRO63A, PRO63E, SER135A, SER182E, SER184E, SER187A, SER187E, SER205E, SER46A, SER76A, THR140A, THR160E, THR273E, THR34A, THR40A, THR54A, THR56A, THR57A, THR59A, THR61A, THR61E, TRP133A, TRP145A, TRP180E, TRP275E, TYR138A, TYR183E, TYR278E, TYR36A, TYR52A, VAL165E, VAL196A, VAL196E, VAL199E, VAL203E, VAL276E, VAL43A, VAL50A, VAL70A, VAL70E, VAL83A, VAL84A
• A-F: ALA111A, ALA234F, ALA238F, ARG104A, ASN241F, ASP154F, GLN109A, GLN144F, GLN151F, GLU240F, GLY108A, GLY236F, GLY58F, HIS155F, HIS158F, HIS159F, HIS244F, HIS30A, ILE105A, LEU110A, LEU147F, LYS112A, LYS156F, LYS33A, PHE242F, PRO239F, PRO31A, SER237F, SER243F, THR106A, THR61F, TRP107A, TRP232F, VAL157F, VAL235F
• A-G: ALA101A, ALA141G, ALA234G, ALA238G, ALA99A, ARG104A, ARG186A, ASN142G, ASN241G, GLN144G, GLN151G, GLU230G, GLY103A, GLY143G, GLY185A, GLY236G, ILE105A, ILE277A, ILE96A, LEU147G, LEU279A, LEU95A, LYS100A, MET139G, PHE231G, PHE242G, PRO229G, SER102A, SER182A, SER184A, SER228G, SER237G, THR233G, THR273A, TRP180A, TRP232G, TYR183A, TYR278A, VAL235G, VAL276A, VAL97A, VAL98A
• A-J: GLY60J, HIS30A, MET62J, PHE64J, PRO63J, THR61J
• B-C: ALA141C, ALA164B, ALA171B, ALA178B, ALA192B, ALA192C, ALA200B, ALA204B, ALA38C, ALA41C, ALA48C, ALA55C, ALA67B, ALA67C, ALA87C, ARG186B, ARG186C, ASN142C, ASN148C, ASP190B, ASP190C, CYS166B, CYS74C, CYS82C, CYS85C, GLN144C, GLU137C, GLU163B, GLU208B, GLY136C, GLY168B, GLY185B, GLY206B, GLY265B, GLY58C, GLY60C, GLY65B, GLY71C, GLY72B, GLY72C, GLY78C, GLY86C, HIS155B, HIS159B, HIS30C, ILE162B, ILE169B, ILE194B, ILE264B, ILE277B, ILE39C, ILE47C, ILE53C, ILE73B, ILE73C, ILE80C, LEU130C, LEU131C, LEU134C, LEU167B, LEU170B, LEU173B, LEU177B, LEU188B, LEU188C, LEU197B, LEU268B, LEU269B, LEU272B, LEU279B, LEU32C, LEU37C, LEU69B, LEU69C, LEU77C, LEU79C, LEU81C, LEU95B, LYS191B, LYS191C, LYS33C, LYS68B, LYS68C, MET132C, MET139C, MET174B, MET181B, MET189B, MET189C, MET195B, MET195C, MET201B, MET62B, MET62C, MET66B, MET66C, PHE128C, PHE193B, PHE193C, PHE202B, PHE207B, PHE215C, PHE35C, PHE44C, PHE49C, PHE51C, PHE64B, PHE75C, PRO198B, PRO31C, PRO63B, PRO63C, SER135C, SER182B, SER184B, SER187B, SER187C, SER205B, SER46C, SER76C, THR140C, THR160B, THR273B, THR34C, THR40C, THR54C, THR56C, THR57C, THR59C, THR61B, THR61C, TRP133C, TRP145C, TRP180B, TRP275B, TYR138C, TYR183B, TYR274B, TYR278B, TYR36C, TYR52C, VAL165B, VAL196B, VAL196C, VAL199B, VAL203B, VAL276B, VAL43C, VAL50C, VAL70B, VAL70C, VAL83C, VAL84C
• B-D: ASP190B, MET189B, MET189D, PHE193B, PHE193D
• B-E: ASP190E, MET189B, MET189E, PHE193B, PHE193E, SER187B, SER187E
• B-G: ALA238G, ARG186B, ARG224G, ASN241G, GLU230G, GLU240G, GLY185B, ILE96B, LEU188B, LEU37B, LYS100B, LYS191B, LYS33B, PHE242G, PRO229G, PRO239G, SER184B, SER187B, SER228G, SER243G, TYR183B, VAL84B
• C-D: ALA141D, ALA164C, ALA171C, ALA178C, ALA192C, ALA192D, ALA200C, ALA204C, ALA38D, ALA41D, ALA48D, ALA55D, ALA67C, ALA67D, ALA87D, ARG186C, ARG186D, ASN142D, ASN148D, ASP190C, ASP190D, CYS166C, CYS176C, CYS74D, CYS82D, CYS85D, GLN144D, GLU137D, GLU163C, GLU208C, GLY136D, GLY168C, GLY185C, GLY206C, GLY261C, GLY265C, GLY271C, GLY58D, GLY60D, GLY65C, GLY71D, GLY72C, GLY72D, GLY78D, GLY86D, HIS155C, HIS159C, HIS30D, ILE162C, ILE169C, ILE194C, ILE264C, ILE277C, ILE39D, ILE47D, ILE53D, ILE73C, ILE73D, ILE80D, LEU127D, LEU130D, LEU131D, LEU134D, LEU167C, LEU170C, LEU173C, LEU177C, LEU188C, LEU188D, LEU197C, LEU268C, LEU269C, LEU272C, LEU279C, LEU32D, LEU37D, LEU69C, LEU69D, LEU77D, LEU81D, LEU95C, LYS191C, LYS191D, LYS33D, LYS68C, LYS68D, MET132D, MET139D, MET174C, MET181C, MET189C, MET189D, MET195C, MET195D, MET201C, MET62C, MET62D, MET66C, MET66D, PHE128D, PHE193C, PHE193D, PHE202C, PHE207C, PHE215D, PHE35D, PHE44D, PHE49D, PHE51D, PHE64C, PHE75D, PRO198C, PRO31D, PRO63C, PRO63D, SER135D, SER182C, SER184C, SER187C, SER187D, SER205C, SER46D, SER76D, THR140D, THR160C, THR273C, THR34D, THR40D, THR54D, THR56D, THR57D, THR59D, THR61C, THR61D, TRP133D, TRP145D, TRP180C, TRP275C, TYR138D, TYR183C, TYR278C, TYR36D, TYR52D, VAL165C, VAL196C, VAL196D, VAL199C, VAL203C, VAL276C, VAL43D, VAL50D, VAL70C, VAL70D, VAL83D, VAL84D
• C-E: ASP190C, MET189C, MET189E, PHE193C, PHE193E, SER187C, SER187E
• C-G: ARG186C, HIS244G
• D-E: ALA141E, ALA164D, ALA171D, ALA178D, ALA192D, ALA192E, ALA200D, ALA204D, ALA48E, ALA55E, ALA67D, ALA67E, ARG186D, ARG186E, ARG280D, ASN142E, ASN148E, ASP190D, ASP190E, CYS166D, CYS176D, CYS74E, CYS82E, CYS85E, GLN144E, GLU137E, GLU163D, GLU208D, GLY136E, GLY168D, GLY185D, GLY206D, GLY58E, GLY60E, GLY65D, GLY71E, GLY72D, GLY72E, GLY78E, GLY86E, HIS155D, HIS159D, HIS30E, ILE162D, ILE169D, ILE194D, ILE264D, ILE277D, ILE39E, ILE47E, ILE53E, ILE73D, ILE73E, ILE80E, LEU127E, LEU130E, LEU131E, LEU134E, LEU167D, LEU170D, LEU173D, LEU177D, LEU188D, LEU188E, LEU197D, LEU268D, LEU269D, LEU272D, LEU279D, LEU32E, LEU37E, LEU69D, LEU77E, LEU79E, LEU81E, LEU95D, LYS191D, LYS191E, LYS29E, LYS33E, LYS68D, LYS68E, MET132E, MET139E, MET174D, MET181D, MET189D, MET189E, MET195D, MET195E, MET201D, MET62D, MET62E, MET66D, MET66E, PHE128E, PHE193D, PHE193E, PHE202D, PHE207D, PHE35E, PHE44E, PHE49E, PHE51E, PHE64D, PHE75E, PRO198D, PRO31E, PRO63D, PRO63E, SER135E, SER182D, SER184D, SER187D, SER187E, SER205D, SER46E, SER76E, THR140E, THR160D, THR273D, THR34E, THR40E, THR54E, THR56E, THR57E, THR59E, THR61D, THR61E, TRP133E, TRP145E, TRP180D, TRP275D, TYR138E, TYR183D, TYR274D, TYR278D, TYR36E, TYR52E, VAL165D, VAL196D, VAL196E, VAL199D, VAL203D, VAL276D, VAL43E, VAL50E, VAL70D, VAL70E, VAL83E, VAL84E
• D-H: ALA234H, ALA238H, ALA99D, ARG186D, ARG280D, ASN142H, ASN241H, GLU230H, GLU240H, GLY143H, GLY185D, GLY236H, ILE277D, LEU279D, MET139H, PHE231H, PHE242H, PRO229H, PRO239H, SER102D, SER184D, SER228H, SER237H, SER243H, THR233H, TRP180D, TRP232H, TYR183D, TYR278D, VAL235H
• E-F: ARG280E, GLY58F, LEU279E, THR61F
• E-H: ALA101E, ALA234H, ALA67H, ALA99E, ARG104E, ARG186E, ASN142H, ASN241H, GLU240H, GLY236H, GLY60H, GLY65H, LEU188E, LYS100E, LYS191E, LYS33E, MET62H, MET66H, PHE64H, PRO63H, SER102E, THR233H, THR59H, THR61H
• E-I: ALA101E, ALA141I, ALA234I, ARG104E, ASN142I, ASN241I, GLN109E, GLN144I, GLU230I, GLY103E, GLY108E, GLY236I, GLY58I, GLY60I, ILE105E, LEU110E, LEU147I, LYS112E, LYS29E, MET62I, PHE231I, PRO31E, PRO63I, SER102E, SER237I, THR106E, THR233I, THR57I, THR59I, THR61I, TRP107E, TRP232I, TYR274E, TYR278E, VAL235I
• E-J: ARG280E, GLY58J, GLY60J, ILE277E, LEU279E, MET62J, PRO63J, THR59J, THR61J, TRP275E, TYR274E, TYR278E
• F-G: ALA141G, ALA164F, ALA171F, ALA178F, ALA192F, ALA192G, ALA200F, ALA204F, ALA41G, ALA48G, ALA55G, ALA67F, ALA67G, ALA87G, ARG186F, ARG186G, ARG280F, ASN142G, ASN148G, ASP190F, ASP190G, CYS166F, CYS176F, CYS74G, CYS82G, CYS85G, GLN144G, GLU137G, GLU163F, GLU208F, GLY136G, GLY168F, GLY185F, GLY185G, GLY206F, GLY265F, GLY271F, GLY58G, GLY60G, GLY65F, GLY71G, GLY72F, GLY72G, GLY78G, GLY86G, HIS155F, HIS159F, HIS30G, ILE162F, ILE169F, ILE194F, ILE264F, ILE277F, ILE39G, ILE47G, ILE53G, ILE73F, ILE73G, ILE80G, LEU127G, LEU130G, LEU131G, LEU134G, LEU167F, LEU170F, LEU173F, LEU177F, LEU188F, LEU188G, LEU197F, LEU268F, LEU269F, LEU272F, LEU279F, LEU32G, LEU37G, LEU69F, LEU77G, LEU79G, LEU81G, LEU95F, LYS191F, LYS191G, LYS33G, LYS68F, LYS68G, MET132G, MET139G, MET174F, MET181F, MET189F, MET189G, MET195F, MET195G, MET201F, MET62F, MET62G, MET66F, MET66G, PHE128G, PHE193F, PHE193G, PHE202F, PHE207F, PHE35G, PHE44G, PHE49G, PHE51G, PHE64F, PHE75G, PRO198F, PRO31G, PRO63F, PRO63G, SER135G, SER182F, SER184F, SER187F, SER187G, SER205F, SER46G, SER76G, THR140G, THR160F, THR273F, THR34G, THR40G, THR54G, THR56G, THR57G, THR59G, THR61F, THR61G, TRP133G, TRP145G, TRP180F, TRP275F, TYR138G, TYR183F, TYR278F, TYR36G, TYR52G, VAL165F, VAL196F, VAL196G, VAL199F, VAL199G, VAL203F, VAL276F, VAL43G, VAL50G, VAL70F, VAL70G, VAL83G, VAL84G
• F-H: ARG186F, ASP190F, MET189F, MET189H, PHE193F, PHE193H, SER187F, SER187H
• F-I: ASP190I, MET189F, MET189I, PHE193F, PHE193I, SER187F
• F-J: ALA141F, ALA164J, ALA171J, ALA178J, ALA192F, ALA192J, ALA200J, ALA204J, ALA38F, ALA41F, ALA48F, ALA55F, ALA67F, ALA67J, ALA87F, ARG186F, ARG186J, ARG280J, ASN142F, ASN148F, ASP190F, ASP190J, ASP88F, CYS166J, CYS176J, CYS74F, CYS82F, CYS85F, GLN144F, GLU137F, GLU163J, GLU208J, GLY136F, GLY168J, GLY185F, GLY185J, GLY206J, GLY261J, GLY58F, GLY60F, GLY65J, GLY71F, GLY72F, GLY72J, GLY78F, GLY86F, HIS155J, HIS159J, HIS30F, ILE162J, ILE169J, ILE194J, ILE264J, ILE277J, ILE39F, ILE47F, ILE53F, ILE73F, ILE73J, ILE80F, LEU130F, LEU131F, LEU134F, LEU167J, LEU170J, LEU173J, LEU177J, LEU188F, LEU188J, LEU197J, LEU268J, LEU269J, LEU272J, LEU279J, LEU32F, LEU37F, LEU69F, LEU69J, LEU77F, LEU79F, LEU81F, LYS191F, LYS191J, LYS29F, LYS33F, LYS68F, LYS68J, MET132F, MET139F, MET174J, MET181J, MET189F, MET189J, MET195F, MET195J, MET201J, MET62F, MET62J, MET66F, MET66J, PHE128F, PHE193F, PHE193J, PHE202J, PHE207J, PHE215F, PHE35F, PHE44F, PHE49F, PHE51F, PHE64J, PHE75F, PRO198J, PRO31F, PRO63F, PRO63J, SER135F, SER182J, SER184J, SER187F, SER187J, SER205J, SER46F, SER76F, THR140F, THR160J, THR273J, THR34F, THR40F, THR54F, THR56F, THR57F, THR59F, THR61F, THR61J, TRP133F, TRP145F, TRP180J, TRP275J, TYR138F, TYR183J, TYR278J, TYR36F, TYR52F, VAL165J, VAL196F, VAL196J, VAL199J, VAL203J, VAL276J, VAL43F, VAL50F, VAL70F, VAL70J, VAL83F, VAL84F
• G-H: ALA141H, ALA164G, ALA171G, ALA178G, ALA192G, ALA192H, ALA200G, ALA204G, ALA48H, ALA55H, ALA67G, ALA67H, ARG186G, ARG186H, ARG280G, ASN142H, ASN148H, ASP190G, ASP190H, CYS166G, CYS74H, CYS82H, CYS85H, GLN144H, GLU137H, GLU163G, GLU208G, GLY136H, GLY168G, GLY185G, GLY206G, GLY261G, GLY265G, GLY271G, GLY58H, GLY60H, GLY65G, GLY71H, GLY72G, GLY78H, GLY86H, HIS155G, HIS159G, HIS30H, ILE162G, ILE169G, ILE194G, ILE264G, ILE277G, ILE39H, ILE47H, ILE53H, ILE73G, ILE73H, ILE80H, LEU127H, LEU130H, LEU131H, LEU134H, LEU167G, LEU170G, LEU173G, LEU177G, LEU188G, LEU188H, LEU197G, LEU268G, LEU269G, LEU272G, LEU279G, LEU32H, LEU37H, LEU69G, LEU77H, LEU79H, LEU81H, LEU95G, LYS191G, LYS191H, LYS29H, LYS33H, LYS68G, LYS68H, MET132H, MET139H, MET174G, MET181G, MET189G, MET189H, MET195G, MET195H, MET201G, MET62G, MET62H, MET66G, MET66H, PHE128H, PHE193G, PHE193H, PHE202G, PHE207G, PHE35H, PHE44H, PHE49H, PHE51H, PHE64G, PHE75H, PRO198G, PRO63G, PRO63H, SER135H, SER182G, SER184G, SER187G, SER187H, SER205G, SER46H, SER76H, THR140H, THR160G, THR273G, THR34H, THR40H, THR54H, THR56H, THR57H, THR59H, THR61G, THR61H, TRP133H, TRP145H, TRP180G, TRP275G, TYR138H, TYR183G, TYR274G, TYR278G, TYR36H, TYR52H, VAL165G, VAL196G, VAL196H, VAL199G, VAL203G, VAL276G, VAL43H, VAL50H, VAL70G, VAL70H, VAL83H, VAL84H
• G-I: ARG186G, ARG186I, ASP190G, MET189G, MET189I, PHE193G, PHE193I, SER187I
• G-J: ARG186G, ARG186J, ASP190J, MET189G, MET189J, PHE193G, PHE193J, SER187G, SER187J
• H-I: ALA141I, ALA164H, ALA171H, ALA178H, ALA192H, ALA192I, ALA200H, ALA204H, ALA38I, ALA41I, ALA48I, ALA55I, ALA67H, ALA67I, ALA87I, ARG186H, ARG186I, ARG280H, ASN148I, ASP190H, ASP190I, CYS166H, CYS176H, CYS74I, CYS82I, CYS85I, GLN144I, GLU137I, GLU163H, GLU208H, GLY136I, GLY146I, GLY168H, GLY185H, GLY206H, GLY265H, GLY58I, GLY60I, GLY65H, GLY71I, GLY72H, GLY72I, GLY78I, GLY86I, HIS155H, HIS159H, HIS30I, ILE162H, ILE169H, ILE194H, ILE264H, ILE277H, ILE39I, ILE47I, ILE53I, ILE73H, ILE73I, ILE80I, LEU127I, LEU130I, LEU131I, LEU134I, LEU167H, LEU170H, LEU173H, LEU177H, LEU188H, LEU188I, LEU197H, LEU268H, LEU269H, LEU272H, LEU279H, LEU32I, LEU37I, LEU69H, LEU77I, LEU79I, LEU81I, LEU95H, LYS191H, LYS191I, LYS29I, LYS33I, LYS68H, LYS68I, MET132I, MET139I, MET174H, MET181H, MET189H, MET189I, MET195H, MET195I, MET201H, MET62H, MET62I, MET66H, MET66I, PHE128I, PHE193H, PHE193I, PHE202H, PHE207H, PHE215I, PHE35I, PHE44I, PHE49I, PHE51I, PHE64H, PHE75I, PRO198H, PRO31I, PRO63H, PRO63I, SER135I, SER182H, SER184H, SER187H, SER187I, SER205H, SER46I, SER76I, THR140I, THR160H, THR273H, THR34I, THR40I, THR54I, THR56I, THR57I, THR59I, THR61H, THR61I, TRP133I, TRP145I, TRP180H, TRP275H, TYR138I, TYR183H, TYR274H, TYR278H, TYR36I, TYR52I, VAL165H, VAL196H, VAL196I, VAL199H, VAL203H, VAL276H, VAL43I, VAL50I, VAL70H, VAL70I, VAL83I, VAL84I
• H-J: ASP190H, MET189H, MET189J, PHE193H, SER187H, SER187J
• I-J: ALA141J, ALA164I, ALA171I, ALA178I, ALA192I, ALA192J, ALA200I, ALA204I, ALA38J, ALA48J, ALA55J, ALA67I, ALA67J, ALA87J, ARG186I, ARG186J, ARG280I, ASN142J, ASN148J, ASP190I, ASP190J, CYS166I, CYS176I, CYS74J, CYS82J, CYS85J, GLN144J, GLU137J, GLU163I, GLU208I, GLY136J, GLY168I, GLY185I, GLY206I, GLY261I, GLY265I, GLY271I, GLY58J, GLY60J, GLY65I, GLY71J, GLY72I, GLY72J, GLY78J, GLY86J, HIS155I, HIS159I, HIS30J, ILE162I, ILE169I, ILE194I, ILE264I, ILE277I, ILE39J, ILE47J, ILE53J, ILE73I, ILE73J, ILE80J, LEU127J, LEU130J, LEU131J, LEU134J, LEU167I, LEU170I, LEU173I, LEU177I, LEU188I, LEU188J, LEU197I, LEU268I, LEU269I, LEU272I, LEU279I, LEU32J, LEU37J, LEU69I, LEU77J, LEU79J, LEU81J, LYS191I, LYS191J, LYS29J, LYS33J, LYS68I, LYS68J, MET132J, MET139J, MET174I, MET181I, MET189I, MET189J, MET195I, MET195J, MET201I, MET219J, MET62I, MET62J, MET66I, MET66J, PHE128J, PHE193I, PHE193J, PHE202I, PHE207I, PHE215J, PHE35J, PHE44J, PHE49J, PHE51J, PHE64I, PHE75J, PRO198I, PRO31J, PRO63I, PRO63J, SER135J, SER182I, SER184I, SER187I, SER187J, SER205I, SER46J, SER76J, THR140J, THR160I, THR273I, THR34J, THR40J, THR54J, THR56J, THR57J, THR59J, THR61I, THR61J, TRP133J, TRP145J, TRP180I, TRP275I, TYR138J, TYR183I, TYR274I, TYR278I, TYR36J, TYR52J, VAL165I, VAL196I, VAL196J, VAL199I, VAL203I, VAL270I, VAL276I, VAL43J, VAL50J, VAL70I, VAL70J, VAL83J, VAL84J