3K81

structure of the central interaction protein from the trypanosoma brucei editosome in complex with single domain antibodies

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 113
  • Norm. En. per Res.: -3.9764
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
C-D	-60.5964	-111.6465	-277.091	-449.3339	113	32	8	12430	6	27	24
C-A	0.0	1.4417	-16.1701	-14.7284	23	1	0	887	0	9	8
C-B	-32.4999	0.0	-122.798	-155.2979	70	5	6	5183	0	11	8
D-A	-12.7924	-17.4392	-156.526	-186.7576	73	10	4	6192	3	12	11
D-B	0.0	-2.7383	-19.967	-22.7053	23	1	0	854	0	14	7

Interface residues

• C-D: ARG100C, ARG100D, ARG98C, ARG98D, ASN110C, ASN110D, ASN23C, ASN23D, ASN96D, ASP55D, ASP68C, ASP68D, CYS109C, CYS109D, CYS94C, CYS94D, GLN104D, GLN119C, GLN119D, GLN121C, GLU106C, GLU106D, GLU66C, GLU66D, GLY29C, GLY29D, GLY97C, GLY97D, HIS112C, HIS112D, HIS124C, HIS69C, HIS69D, HIS70C, HIS70D, ILE118C, ILE118D, ILE130C, ILE130D, ILE54C, ILE54D, ILE72C, ILE72D, LEU101C, LEU101D, LEU105D, LEU27C, LEU27D, LEU49C, LEU49D, LEU99C, LEU99D, LYS111C, LYS111D, LYS20C, LYS67C, LYS67D, PHE113C, PHE113D, PHE115C, PHE115D, PHE75C, PRO103C, PRO103D, PRO107C, PRO107D, PRO116C, PRO116D, PRO122C, PRO123C, SER102C, SER102D, SER108C, SER108D, SER21C, SER21D, SER24C, SER24D, SER53C, SER53D, THR26C, THR26D, THR48C, THR48D, THR50C, THR50D, THR51C, THR51D, THR52C, THR52D, THR56D, THR71C, THR71D, TYR114C, TYR114D, TYR117C, TYR117D, VAL22C, VAL22D, VAL25C, VAL25D, VAL28C, VAL28D, VAL30C, VAL30D, VAL65C, VAL65D, VAL92C, VAL92D, VAL93C, VAL93D, VAL95C, VAL95D
• C-A: ALA40A, ARG39A, ARG45A, ARG56A, ASN110C, CYS109C, GLN100A, GLN44A, GLU66C, GLY102A, GLY42A, HIS112C, ILE54C, LYS111C, LYS43A, LYS67C, PHE113C, PRO41A, THR101A, TYR114C, VAL63C, VAL64C, VAL65C
• C-B: ALA107B, ALA33B, ALA49B, ALA50B, ALA97B, ARG100C, ARG108B, ARG45B, ARG56B, ARG73C, ASN110C, ASN52B, ASN53B, ASN58B, ASN96B, ASN98B, ASP42C, ASP61B, CYS109C, GLN100B, GLN104C, GLN35C, GLN44B, GLN46C, GLU106C, GLU41C, GLU46B, GLU54B, GLY102B, GLY106B, GLY35B, GLY37C, GLY55B, HIS112C, ILE48B, ILE51B, LEU104B, LEU105C, LEU109B, LEU47B, LEU99B, LYS111C, LYS64B, PHE113C, PHE115C, PHE38C, PHE75C, PRO103C, PRO107C, PRO116C, PRO4B, SER102C, SER105B, SER108C, SER36C, THR101B, THR103B, THR45C, THR57B, THR71C, TRP111B, TRP34B, TYR110B, TYR117C, TYR37B, TYR40C, TYR59B, VAL39C, VAL44C, VAL60B
• D-A: ALA107A, ALA33A, ALA43D, ALA49A, ALA50A, ALA97A, ARG100D, ARG108A, ARG45A, ARG56A, ARG71A, ARG73D, ASN110D, ASN52A, ASN53A, ASN58A, ASN96A, ASN98A, ASP42D, ASP61A, CYS109D, GLN100A, GLN104D, GLN35D, GLN44A, GLN46D, GLU106D, GLU41D, GLU46A, GLU54A, GLY102A, GLY106A, GLY112A, GLY35A, GLY37D, GLY55A, HIS112D, ILE51A, LEU104A, LEU105D, LEU109A, LEU47A, LEU99A, LYS111D, LYS64A, PHE113D, PHE115D, PHE38D, PRO103D, PRO107D, PRO116D, PRO4A, SER102D, SER105A, SER108D, SER36D, THR101A, THR103A, THR45D, THR57A, THR71D, TRP111A, TRP34A, TYR110A, TYR114D, TYR117D, TYR37A, TYR40D, TYR59A, VAL39D, VAL44D, VAL60A, VAL69A
• D-B: ALA40B, ARG39B, ARG45B, ASN58B, ASP55D, CYS109D, GLN44B, GLU62D, GLU66D, GLY42B, HIS112D, ILE54D, LYS111D, LYS43B, LYS67D, PHE113D, PRO41B, SER53D, THR101B, THR103B, VAL63D, VAL64D, VAL65D