3K2W

crystal structure of betaine-aldehyde dehydrogenase from pseudoalteromonas atlantica t6c

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: F-H
  • Int. Res.: 248
  • Norm. En. per Res.: -4.7403
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-61.3145	13.0032	-267.526	-315.8374	103	9	6	10113	4	41	19
A-C	-259.0631	-106.8799	-720.262	-1086.2051	242	38	16	28418	9	105	74
A-D	-30.8368	7.1813	-143.722	-167.3776	101	6	2	6898	6	30	23
B-C	-35.3616	11.573	-139.795	-163.5836	101	7	2	6947	5	29	25
B-D	-237.1816	-96.3833	-739.388	-1072.9529	244	29	16	28883	7	101	69
C-D	-55.6207	17.7324	-269.134	-307.0224	102	8	6	10159	2	42	16
C-F	0.0	47.3869	-11.9883	35.3986	28	0	0	845	0	17	18
D-G	-5.4599	-5.38	-32.0889	-42.9288	49	1	0	1900	1	24	20
E-F	-54.1008	17.6756	-264.998	-301.4232	103	7	6	9986	3	41	19
E-G	-243.3263	-136.0563	-719.291	-1098.6735	232	31	17	27860	11	104	75
E-H	-26.1503	7.0129	-146.884	-166.0215	108	11	2	7159	6	28	28
F-G	-24.2011	7.2801	-138.617	-155.538	99	6	2	6787	6	29	23
F-H	-250.3565	-136.4887	-788.745	-1175.5902	248	32	15	29879	12	110	76
G-H	-55.2825	28.0339	-270.127	-297.3756	101	7	6	10098	2	42	18

Interface residues

• A-B: ALA123A, ALA123B, ALA428A, ALA428B, ALA487A, ALA487B, ALA63A, ALA63B, ALA65A, ALA65B, ALA69A, ALA69B, ARG70A, ARG70B, ARG72A, ARG72B, ASN122A, ASN122B, ASN135A, ASN135B, ASN429A, ASN429B, ASN431A, ASN431B, ASN445A, ASN445B, ASN74A, ASN74B, ASP129A, ASP129B, ASP134A, ASP134B, ASP137A, ASP137B, GLN136A, GLN136B, GLN425A, GLN425B, GLU127A, GLU127B, GLU138A, GLU138B, GLU486A, GLU486B, GLY128A, GLY128B, HIS143A, HIS143B, ILE126A, ILE126B, ILE130A, ILE130B, ILE140A, ILE140B, ILE142A, ILE142B, ILE430A, ILE430B, ILE434A, ILE434B, ILE444A, ILE444B, ILE484A, ILE484B, LEU124A, LEU124B, LEU131A, LEU131B, LEU67A, LEU67B, LYS139A, LYS139B, LYS144A, LYS144B, LYS480A, LYS480B, LYS66A, LYS66B, PHE427A, PHE427B, PRO132A, PRO132B, SER133A, SER133B, SER426A, SER426B, THR125A, THR125B, THR424A, THR424B, THR481A, THR481B, THR68A, THR68B, THR71A, THR71B, TRP64A, TYR141A, TYR141B, VAL145A, VAL145B, VAL482A, VAL482B
• A-C: ALA246A, ALA246C, ALA420A, ALA420C, ALA433A, ALA433C, ALA487A, ALA487C, ARG147A, ARG147C, ARG165C, ARG446A, ARG446C, ASN135A, ASN135C, ASN412A, ASN412C, ASN431A, ASN431C, ASN445A, ASN445C, ASN457A, ASN457C, ASN485A, ASN485C, ASP129A, ASP129C, ASP134A, ASP134C, ASP137A, ASP269A, ASP269C, ASP276A, ASP276C, ASP436A, ASP436C, ASP468A, ASP468C, GLN136A, GLN136C, GLN240A, GLN240C, GLN425A, GLN425C, GLN432A, GLN432C, GLN451A, GLN451C, GLN453A, GLN453C, GLN461A, GLN461C, GLN475A, GLN475C, GLU127A, GLU127C, GLU138A, GLU138C, GLU247A, GLU247C, GLU255A, GLU255C, GLU438A, GLU438C, GLU441A, GLU441C, GLU450A, GLU450C, GLU467A, GLU474A, GLU474C, GLU478A, GLU478C, GLU486A, GLU486C, GLU488A, GLU488C, GLY128A, GLY128C, GLY238A, GLY238C, GLY257A, GLY257C, GLY440A, GLY440C, GLY447A, GLY447C, GLY449A, GLY449C, GLY454A, GLY454C, GLY458A, GLY458C, GLY463A, GLY463C, GLY465A, GLY465C, GLY466A, GLY466C, GLY469A, GLY469C, GLY472A, GLY472C, HIS143A, HIS143C, HIS423A, HIS423C, HIS452A, HIS452C, HIS456A, HIS456C, ILE130A, ILE130C, ILE140A, ILE140C, ILE142A, ILE142C, ILE229C, ILE241A, ILE241C, ILE415A, ILE415C, ILE430A, ILE430C, ILE434A, ILE434C, ILE444A, ILE444C, ILE484A, ILE484C, LEU131A, LEU131C, LEU254A, LEU254C, LEU256A, LEU256C, LEU418A, LEU418C, LEU437A, LEU437C, LEU477A, LEU477C, LYS139A, LYS139C, LYS144A, LYS144C, LYS227A, LYS227C, LYS239A, LYS239C, LYS243A, LYS243C, LYS272A, LYS272C, LYS460A, LYS460C, LYS470A, LYS470C, LYS479A, LYS479C, LYS480A, LYS480C, LYS62A, LYS62C, LYS66A, LYS66C, MET228A, MET228C, MET249A, MET249C, MET253A, MET253C, MET448A, PHE427A, PHE427C, PHE455A, PHE455C, PHE464A, PHE464C, PHE471A, PHE471C, PRO132A, PRO132C, PRO146A, PRO146C, PRO224A, PRO224C, PRO251A, PRO251C, SER133A, SER133C, SER234A, SER245A, SER245C, SER419A, SER419C, SER435A, SER435C, SER462A, SER462C, THR114A, THR114C, THR235A, THR235C, THR244A, THR244C, THR250A, THR250C, THR424C, THR481A, THR481C, TRP459A, TRP459C, TYR118A, TYR118C, TYR141A, TYR141C, TYR242A, TYR242C, TYR248A, TYR248C, TYR416A, TYR416C, TYR421A, TYR421C, TYR443A, TYR443C, TYR483A, TYR483C, VAL145A, VAL145C, VAL236A, VAL252A, VAL252C, VAL422A, VAL422C, VAL439A, VAL439C, VAL442A, VAL442C, VAL482A, VAL482C
• A-D: ALA113A, ALA113D, ALA123A, ALA123D, ALA428A, ALA428D, ALA487A, ALA487D, ALA69A, ALA69D, ARG70A, ARG70D, ARG77A, ARG77D, ARG84A, ARG84D, ASN122A, ASN122D, ASN429D, ASN431A, ASN431D, ASN485A, ASN485D, ASN74A, ASN74D, ASN81A, ASN81D, ASP110A, ASP110D, ASP117A, ASP117D, ASP121A, ASP121D, ASP137A, ASP137D, CYS120A, CYS120D, GLN432A, GLN432D, GLN451A, GLN451D, GLN453A, GLN453D, GLN73A, GLN73D, GLU127A, GLU127D, GLU138A, GLU138D, GLU405D, GLU486A, GLU486D, GLU488A, GLY119D, GLY128A, GLY128D, GLY454A, GLY454D, GLY469A, GLY469D, HIS452A, HIS452D, ILE126A, ILE126D, ILE130A, ILE130D, ILE430A, ILE430D, ILE434A, ILE434D, ILE484A, ILE484D, LEU124A, LEU124D, LEU473A, LEU473D, LYS139A, LYS139D, LYS470A, LYS470D, PHE115A, PHE115D, PHE427A, PHE427D, PHE471A, PHE471D, SER426D, SER435A, SER435D, THR114A, THR114D, THR125A, THR125D, THR68A, THR68D, TYR118A, TYR118D, TYR141A, TYR141D, VAL111A, VAL111D
• B-C: ALA113B, ALA113C, ALA123B, ALA123C, ALA428B, ALA428C, ALA487B, ALA487C, ALA69B, ALA69C, ARG70B, ARG70C, ARG77B, ARG77C, ARG84B, ARG84C, ASN122B, ASN122C, ASN429C, ASN431B, ASN431C, ASN485B, ASN485C, ASN74B, ASN74C, ASN81B, ASN81C, ASP110B, ASP110C, ASP117B, ASP117C, ASP121B, ASP121C, ASP137B, ASP137C, CYS120B, CYS120C, GLN432B, GLN432C, GLN451B, GLN451C, GLN453B, GLN453C, GLN73B, GLN73C, GLU127B, GLU127C, GLU138B, GLU138C, GLU486B, GLU486C, GLU488B, GLU488C, GLY119B, GLY119C, GLY128B, GLY128C, GLY454B, GLY454C, GLY469B, GLY469C, HIS452B, HIS452C, ILE126B, ILE126C, ILE130B, ILE130C, ILE430C, ILE434B, ILE434C, ILE484B, ILE484C, LEU124B, LEU124C, LEU473B, LEU473C, LYS139B, LYS139C, LYS470B, LYS470C, PHE115B, PHE115C, PHE427B, PHE427C, PHE471B, PHE471C, SER426C, SER435B, SER435C, THR114B, THR114C, THR125B, THR125C, THR68B, THR68C, TYR118B, TYR118C, TYR141B, TYR141C, VAL111B, VAL111C
• B-D: ALA246B, ALA246D, ALA420B, ALA420D, ALA433B, ALA433D, ALA487B, ALA487D, ARG147B, ARG147D, ARG165B, ARG165D, ARG446B, ARG446D, ASN135B, ASN135D, ASN412B, ASN412D, ASN431B, ASN431D, ASN445B, ASN445D, ASN457B, ASN457D, ASN485B, ASN485D, ASP129B, ASP129D, ASP134B, ASP134D, ASP137D, ASP269D, ASP276B, ASP276D, ASP436B, ASP436D, ASP468B, ASP468D, GLN136B, GLN136D, GLN240B, GLN240D, GLN425B, GLN425D, GLN432B, GLN432D, GLN451B, GLN451D, GLN453B, GLN453D, GLN461B, GLN461D, GLN475B, GLN475D, GLU127B, GLU127D, GLU138B, GLU138D, GLU247B, GLU247D, GLU255B, GLU255D, GLU438B, GLU438D, GLU441B, GLU441D, GLU450B, GLU450D, GLU467B, GLU474B, GLU474D, GLU478B, GLU478D, GLU486B, GLU486D, GLU488B, GLY128B, GLY128D, GLY238B, GLY238D, GLY257B, GLY257D, GLY417D, GLY440B, GLY440D, GLY447B, GLY447D, GLY449B, GLY449D, GLY454B, GLY454D, GLY458B, GLY458D, GLY463B, GLY463D, GLY465B, GLY465D, GLY466B, GLY466D, GLY469B, GLY469D, GLY472B, GLY472D, HIS143B, HIS143D, HIS423B, HIS423D, HIS452B, HIS452D, HIS456B, HIS456D, ILE130B, ILE130D, ILE140B, ILE140D, ILE142B, ILE142D, ILE229B, ILE229D, ILE241B, ILE241D, ILE408B, ILE415B, ILE415D, ILE430B, ILE430D, ILE434B, ILE434D, ILE444B, ILE444D, ILE484B, ILE484D, LEU131B, LEU131D, LEU254B, LEU254D, LEU256B, LEU256D, LEU418B, LEU418D, LEU437B, LEU437D, LEU477B, LEU477D, LYS139B, LYS139D, LYS144B, LYS144D, LYS227B, LYS227D, LYS239B, LYS239D, LYS243B, LYS243D, LYS272B, LYS272D, LYS460B, LYS460D, LYS470B, LYS470D, LYS479B, LYS479D, LYS480B, LYS480D, LYS62B, LYS62D, MET228B, MET228D, MET249B, MET249D, MET253B, MET253D, MET448B, MET448D, PHE427B, PHE427D, PHE455B, PHE455D, PHE464B, PHE464D, PHE471B, PHE471D, PRO132B, PRO132D, PRO146B, PRO146D, PRO224B, PRO224D, PRO251B, PRO251D, SER133B, SER133D, SER234D, SER245B, SER245D, SER419B, SER419D, SER435B, SER435D, SER462B, SER462D, THR114B, THR114D, THR235B, THR235D, THR244B, THR244D, THR250B, THR250D, THR424B, THR424D, THR481B, THR481D, TRP459B, TRP459D, TYR118B, TYR118D, TYR141B, TYR141D, TYR242B, TYR242D, TYR248B, TYR248D, TYR416B, TYR416D, TYR421B, TYR421D, TYR443B, TYR443D, TYR483B, TYR483D, VAL145B, VAL145D, VAL236D, VAL252B, VAL252D, VAL422B, VAL422D, VAL439B, VAL439D, VAL442B, VAL442D, VAL482B, VAL482D
• C-D: ALA123C, ALA123D, ALA428C, ALA428D, ALA487C, ALA63C, ALA63D, ALA65C, ALA65D, ALA69C, ALA69D, ARG70C, ARG70D, ARG72C, ARG72D, ASN122C, ASN122D, ASN135C, ASN135D, ASN429C, ASN429D, ASN431C, ASN431D, ASN445C, ASN445D, ASN74C, ASP129C, ASP129D, ASP134C, ASP134D, ASP137C, ASP137D, GLN136C, GLN136D, GLN425C, GLN425D, GLU127C, GLU127D, GLU138C, GLU138D, GLU486C, GLU486D, GLU488C, GLY128C, GLY128D, HIS143C, HIS143D, ILE126C, ILE126D, ILE130C, ILE130D, ILE140C, ILE140D, ILE142C, ILE142D, ILE430C, ILE430D, ILE434C, ILE434D, ILE444C, ILE444D, ILE484C, ILE484D, LEU124C, LEU124D, LEU131C, LEU131D, LEU67C, LEU67D, LYS139C, LYS139D, LYS144C, LYS144D, LYS480C, LYS480D, LYS62C, LYS66C, LYS66D, PHE427C, PHE427D, PRO132C, PRO132D, SER133C, SER133D, SER426C, SER426D, THR125C, THR125D, THR424C, THR424D, THR481C, THR481D, THR68C, THR68D, THR71C, THR71D, TYR141C, TYR141D, VAL145C, VAL145D, VAL482C, VAL482D
• C-F: ALA299C, ALA307F, ALA324F, ASP303C, ASP323F, ASP325F, ASP379C, ASP383C, GLN327F, GLN382C, GLN406C, GLU364F, GLU409C, GLY315F, GLY319F, LEU310F, LEU312F, LEU316F, LYS308F, LYS314F, LYS317F, LYS381C, LYS400C, PHE410C, PRO311F, SER402C, TYR302C, VAL318F
• D-G: ALA307D, ALA324D, ALA59G, ASN10G, ASN13G, ASN23G, ASN52G, ASP203G, ASP271D, ASP323D, ASP325D, GLN18G, GLN327D, GLU275D, GLU364D, GLU373D, GLU41G, GLY16G, GLY17G, GLY315D, HIS7G, ILE15G, LEU278D, LEU310D, LEU312D, LEU316D, LYS11G, LYS197G, LYS308D, LYS314D, LYS317D, LYS359D, LYS9G, PHE309D, PHE8G, PRO21G, PRO311D, PRO374D, SER25G, THR27G, THR356D, THR362D, TYR19G, VAL12G, VAL20G, VAL313D, VAL318D, VAL363D, VAL56G
• E-F: ALA123E, ALA123F, ALA428E, ALA428F, ALA487E, ALA63E, ALA63F, ALA65E, ALA65F, ALA69E, ALA69F, ARG70E, ARG70F, ARG72E, ARG72F, ASN122E, ASN122F, ASN135E, ASN135F, ASN429E, ASN429F, ASN431E, ASN431F, ASN445E, ASN445F, ASN74E, ASP129E, ASP129F, ASP134E, ASP134F, ASP137E, ASP137F, GLN136E, GLN136F, GLN425E, GLN425F, GLU127E, GLU127F, GLU138E, GLU138F, GLU486E, GLU486F, GLY128E, GLY128F, HIS143E, HIS143F, ILE126E, ILE126F, ILE130E, ILE130F, ILE140E, ILE140F, ILE142E, ILE142F, ILE430E, ILE430F, ILE434E, ILE434F, ILE444E, ILE444F, ILE484E, ILE484F, LEU124E, LEU124F, LEU131E, LEU131F, LEU67E, LEU67F, LYS139E, LYS139F, LYS144E, LYS144F, LYS480E, LYS480F, LYS62E, LYS66E, LYS66F, PHE427E, PHE427F, PRO132E, PRO132F, SER133E, SER133F, SER426E, SER426F, THR125E, THR125F, THR424E, THR424F, THR481E, THR481F, THR68E, THR68F, THR71E, THR71F, TRP64E, TRP64F, TYR141E, TYR141F, VAL145E, VAL145F, VAL482E, VAL482F
• E-G: ALA246E, ALA246G, ALA420E, ALA420G, ALA433E, ALA433G, ALA487E, ALA487G, ARG147E, ARG147G, ARG165E, ARG165G, ARG446E, ARG446G, ASN135E, ASN135G, ASN412E, ASN412G, ASN431E, ASN431G, ASN445E, ASN445G, ASN457E, ASN457G, ASN485E, ASN485G, ASP129E, ASP129G, ASP134E, ASP134G, ASP137E, ASP137G, ASP269E, ASP269G, ASP276E, ASP276G, ASP436E, ASP436G, ASP468E, ASP468G, GLN136E, GLN136G, GLN240E, GLN240G, GLN425E, GLN425G, GLN432E, GLN432G, GLN451E, GLN451G, GLN453E, GLN453G, GLN461E, GLN461G, GLN475E, GLN475G, GLU127E, GLU127G, GLU138E, GLU138G, GLU247E, GLU247G, GLU255G, GLU438E, GLU438G, GLU441E, GLU441G, GLU450E, GLU450G, GLU467E, GLU474E, GLU474G, GLU478E, GLU478G, GLU486E, GLU486G, GLU488E, GLU488G, GLY128E, GLY128G, GLY238E, GLY238G, GLY257E, GLY257G, GLY440E, GLY440G, GLY447E, GLY447G, GLY449E, GLY449G, GLY454E, GLY454G, GLY458E, GLY458G, GLY463E, GLY463G, GLY465E, GLY465G, GLY466E, GLY466G, GLY469E, GLY469G, GLY472E, GLY472G, HIS143E, HIS143G, HIS423E, HIS423G, HIS452E, HIS452G, HIS456E, HIS456G, ILE130E, ILE130G, ILE140E, ILE140G, ILE142E, ILE142G, ILE241E, ILE241G, ILE415E, ILE430E, ILE430G, ILE434E, ILE434G, ILE444E, ILE444G, ILE484E, ILE484G, LEU131E, LEU131G, LEU254E, LEU254G, LEU256E, LEU256G, LEU418E, LEU418G, LEU437E, LEU437G, LEU477E, LEU477G, LYS139E, LYS139G, LYS144E, LYS144G, LYS227E, LYS227G, LYS239E, LYS239G, LYS243E, LYS243G, LYS272E, LYS272G, LYS460E, LYS460G, LYS470E, LYS470G, LYS479E, LYS479G, LYS480E, LYS480G, LYS62E, LYS62G, MET228E, MET228G, MET249E, MET249G, MET448E, MET448G, PHE427E, PHE427G, PHE455E, PHE455G, PHE464E, PHE464G, PHE471E, PHE471G, PRO132E, PRO132G, PRO146E, PRO146G, PRO251E, PRO251G, SER133E, SER133G, SER245E, SER245G, SER419E, SER419G, SER435E, SER435G, SER462E, SER462G, THR114E, THR114G, THR235E, THR235G, THR244E, THR244G, THR250E, THR250G, THR290E, THR481E, THR481G, TRP459E, TRP459G, TYR118E, TYR118G, TYR141E, TYR141G, TYR242E, TYR242G, TYR248E, TYR248G, TYR421E, TYR421G, TYR443E, TYR443G, TYR483E, TYR483G, VAL145E, VAL145G, VAL252E, VAL252G, VAL422E, VAL422G, VAL439E, VAL439G, VAL442E, VAL442G, VAL482E, VAL482G
• E-H: ALA113E, ALA113H, ALA123E, ALA123H, ALA428E, ALA428H, ALA487E, ALA487H, ALA69E, ALA69H, ARG70E, ARG70H, ARG77E, ARG77H, ARG84E, ARG84H, ASN122E, ASN122H, ASN429E, ASN429H, ASN431E, ASN431H, ASN485E, ASN485H, ASN74E, ASN74H, ASN81E, ASN81H, ASP110E, ASP110H, ASP117E, ASP117H, ASP121E, ASP121H, ASP129E, ASP129H, ASP137E, ASP137H, CYS120E, CYS120H, GLN432E, GLN432H, GLN451E, GLN451H, GLN453E, GLN453H, GLN73E, GLN73H, GLU127E, GLU127H, GLU138E, GLU138H, GLU405H, GLU486E, GLU486H, GLU488E, GLU488H, GLY119E, GLY119H, GLY128E, GLY128H, GLY454E, GLY454H, GLY469E, GLY469H, GLY489H, HIS452E, HIS452H, ILE126E, ILE126H, ILE130E, ILE130H, ILE430E, ILE430H, ILE434E, ILE434H, ILE484E, ILE484H, LEU124E, LEU124H, LEU473E, LEU473H, LYS139E, LYS139H, LYS470E, LYS470H, PHE115E, PHE115H, PHE427E, PHE427H, PHE471E, PHE471H, SER426E, SER426H, SER435E, SER435H, THR114E, THR114H, THR125E, THR125H, THR68E, THR68H, TYR118E, TYR118H, TYR141E, TYR141H, VAL111E, VAL111H
• F-G: ALA113F, ALA113G, ALA123F, ALA123G, ALA428F, ALA428G, ALA487F, ALA487G, ALA69F, ALA69G, ARG70F, ARG70G, ARG77F, ARG77G, ARG84F, ARG84G, ASN122F, ASN122G, ASN429F, ASN431F, ASN431G, ASN485F, ASN485G, ASN74F, ASN74G, ASN81F, ASN81G, ASP110F, ASP110G, ASP117F, ASP117G, ASP121F, ASP121G, ASP137F, ASP137G, CYS120F, CYS120G, GLN432F, GLN432G, GLN451F, GLN451G, GLN453F, GLN453G, GLN73F, GLN73G, GLU127F, GLU127G, GLU138F, GLU138G, GLU486F, GLU486G, GLU488G, GLY119F, GLY119G, GLY128F, GLY128G, GLY454F, GLY454G, GLY469F, GLY469G, HIS452F, HIS452G, ILE126F, ILE126G, ILE130F, ILE130G, ILE430F, ILE434F, ILE434G, ILE484F, ILE484G, LEU124F, LEU124G, LEU473F, LEU473G, LYS139F, LYS139G, LYS470F, LYS470G, PHE115F, PHE115G, PHE427F, PHE427G, PHE471F, PHE471G, SER435F, SER435G, THR114F, THR114G, THR125F, THR125G, THR68F, THR68G, TYR118F, TYR118G, TYR141F, TYR141G, VAL111F, VAL111G
• F-H: ALA246F, ALA246H, ALA268F, ALA273F, ALA420F, ALA420H, ALA433F, ALA433H, ALA487F, ALA487H, ARG147F, ARG147H, ARG165F, ARG165H, ARG446F, ARG446H, ASN135F, ASN135H, ASN412F, ASN412H, ASN431F, ASN431H, ASN445F, ASN445H, ASN457F, ASN457H, ASN485F, ASN485H, ASP129F, ASP129H, ASP134F, ASP134H, ASP137H, ASP267F, ASP269F, ASP271F, ASP276F, ASP276H, ASP436F, ASP436H, ASP468F, ASP468H, GLN136F, GLN136H, GLN240F, GLN240H, GLN425F, GLN425H, GLN432F, GLN432H, GLN451F, GLN451H, GLN453F, GLN453H, GLN461F, GLN461H, GLN475F, GLN475H, GLU127F, GLU127H, GLU138F, GLU138H, GLU247F, GLU247H, GLU255F, GLU255H, GLU438F, GLU438H, GLU441F, GLU441H, GLU450F, GLU450H, GLU474F, GLU474H, GLU478F, GLU478H, GLU486F, GLU486H, GLU488H, GLY128F, GLY128H, GLY238F, GLY238H, GLY257F, GLY257H, GLY417F, GLY440F, GLY440H, GLY447F, GLY447H, GLY449F, GLY449H, GLY454F, GLY454H, GLY458F, GLY458H, GLY463F, GLY463H, GLY465F, GLY465H, GLY466F, GLY466H, GLY469F, GLY469H, GLY472F, GLY472H, GLY489H, HIS143F, HIS143H, HIS423F, HIS423H, HIS452F, HIS452H, HIS456F, HIS456H, HIS490H, ILE130F, ILE130H, ILE140F, ILE140H, ILE142F, ILE142H, ILE229F, ILE229H, ILE241F, ILE241H, ILE408F, ILE415F, ILE415H, ILE430F, ILE430H, ILE434F, ILE434H, ILE444F, ILE444H, ILE484F, ILE484H, LEU131F, LEU131H, LEU254F, LEU254H, LEU256F, LEU256H, LEU270F, LEU418F, LEU418H, LEU437F, LEU437H, LEU477F, LEU477H, LYS139F, LYS139H, LYS144F, LYS144H, LYS227F, LYS227H, LYS239F, LYS239H, LYS243F, LYS243H, LYS272F, LYS272H, LYS460F, LYS460H, LYS470F, LYS470H, LYS479F, LYS479H, LYS480F, LYS480H, LYS62F, LYS66H, MET228F, MET228H, MET249F, MET249H, MET253F, MET253H, MET448F, MET448H, PHE427F, PHE427H, PHE455F, PHE455H, PHE464F, PHE464H, PHE471F, PHE471H, PRO132F, PRO132H, PRO146F, PRO146H, PRO224F, PRO224H, PRO251F, PRO251H, SER133F, SER133H, SER245F, SER245H, SER419F, SER419H, SER435F, SER435H, SER462F, SER462H, THR114F, THR114H, THR235F, THR235H, THR244F, THR244H, THR250F, THR250H, THR290H, THR424F, THR481F, THR481H, TRP459F, TRP459H, TYR118F, TYR118H, TYR141F, TYR141H, TYR242F, TYR242H, TYR248F, TYR248H, TYR416F, TYR416H, TYR421F, TYR421H, TYR443F, TYR443H, TYR483F, TYR483H, VAL145F, VAL145H, VAL252F, VAL252H, VAL422F, VAL422H, VAL439F, VAL439H, VAL442F, VAL442H, VAL482F, VAL482H
• G-H: ALA123G, ALA123H, ALA428G, ALA428H, ALA63G, ALA63H, ALA65G, ALA65H, ALA69G, ALA69H, ARG70G, ARG70H, ARG72G, ARG72H, ASN122G, ASN122H, ASN135G, ASN135H, ASN429G, ASN429H, ASN431G, ASN431H, ASN445G, ASN445H, ASN74G, ASP129G, ASP129H, ASP134G, ASP134H, ASP137G, ASP137H, GLN136G, GLN136H, GLN425G, GLN425H, GLU127G, GLU127H, GLU138G, GLU138H, GLU486G, GLU486H, GLY128G, GLY128H, HIS143G, HIS143H, ILE126G, ILE126H, ILE130G, ILE130H, ILE140G, ILE140H, ILE142G, ILE142H, ILE430G, ILE430H, ILE434G, ILE434H, ILE444G, ILE444H, ILE484G, ILE484H, LEU124G, LEU124H, LEU131G, LEU131H, LEU67G, LEU67H, LYS139G, LYS139H, LYS144G, LYS144H, LYS480G, LYS480H, LYS62H, LYS66G, LYS66H, PHE427G, PHE427H, PRO132G, PRO132H, SER133G, SER133H, SER426G, SER426H, THR125G, THR125H, THR424G, THR424H, THR481G, THR481H, THR68G, THR68H, THR71G, THR71H, TRP64H, TYR141G, TYR141H, VAL145G, VAL145H, VAL482G, VAL482H