3JUT

acidic fibroblast growth factor (fgf-1) complexed with gentisic acid

• Total interactions analyzed: 15
• Total true interactions: 6
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 14
  • Norm. En. per Res.: -5.6138
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-11.7245	-19.2213	-101.243	-132.1888	53	1	1	4286	1	18	14
A-F	0.0	0.0	-0.5791	-0.5791	8	0	0	116	0	8	3
B-C	0.0	0.0	-41.4097	-41.4097	33	0	0	2029	0	3	3
D-E	-10.7331	18.7175	-127.495	-119.5106	62	7	3	5433	0	19	18
D-F	-12.9034	-15.815	-95.3158	-124.0342	51	8	1	4088	0	16	11
E-F	-28.0193	-28.3401	-22.2343	-78.5936	14	3	0	1005	2	8	10

Interface residues

• A-B: ARG16A, ARG27B, ARG29A, ARG29B, ASN10B, ASN84B, ASP20A, ASP28A, ASP28B, ASP31A, ASP31B, CYS8B, GLN32A, GLN55A, GLN69A, GLU52A, GLU83B, GLY11B, GLY12B, GLY21A, GLY54A, GLY67A, HIS13B, HIS33A, HIS85B, ILE17A, ILE34B, LEU123B, LEU125B, LEU127B, LEU18A, LEU5B, LEU6B, LYS120B, PHE14B, PRO126B, PRO128B, PRO19A, SER130B, SER30A, SER30B, SER68A, SER9B, THR22A, THR26A, THR53A, THR70A, TYR56A, TYR66A, TYR7B, TYR86B, VAL129B, VAL23A
• A-F: ARG114F, ASN72A, GLU73A, LYS104F, LYS105F, PRO71A, THR61A, THR70A
• B-C: ASN72B, ASN72C, GLN37B, GLN55B, GLN55C, GLN69B, GLN69C, GLU41C, GLU52B, GLU52C, GLY54B, GLY54C, HIS33C, LYS1B, LYS49B, LYS49C, PRO19B, PRO19C, PRO71B, PRO71C, SER50B, SER50C, SER68B, SER68C, THR51B, THR51C, THR53B, THR53C, THR70B, THR70C, TYR47C, TYR56B, TYR56C
• D-E: ALA40E, ALA95D, ARG80D, ASN84D, ASN84E, ASN87D, ASN87E, ASN98D, CYS8E, GLN37E, GLU45D, GLU79D, GLU79E, GLU82D, GLU82E, GLU83D, GLU83E, GLU96D, GLY12E, GLY44D, HIS85D, HIS85E, HIS94D, ILE90D, LEU123E, LEU125D, LEU125E, LEU127E, LEU36E, LEU38E, LEU5E, LEU6E, LEU78D, LEU81D, LEU81E, LYS120E, LYS1E, LYS2E, LYS4D, LYS4E, LYS92D, LYS97D, PHE100D, PHE124E, PHE14E, PRO126D, PRO126E, PRO128E, PRO3E, SER39E, SER42D, SER91D, SER9E, THR88D, TRP99D, TYR117D, TYR7E, TYR86D, TYR86E, VAL129E, VAL43D, VAL46E
• D-F: ARG16F, ARG27D, ARG29D, ASN10D, ASN84D, ASP20F, ASP28D, ASP28F, ASP31D, ASP31F, CYS8D, GLN32F, GLN55F, GLN69F, GLU52F, GLY11D, GLY12D, GLY21F, GLY54F, GLY67F, HIS13D, HIS33F, HIS85D, ILE17F, ILE34D, LEU125D, LEU127D, LEU18F, LEU5D, LEU6D, LYS120D, LYS4D, PHE14D, PRO126D, PRO128D, PRO19F, SER130D, SER30D, SER30F, SER50F, SER68F, SER9D, THR22F, THR53F, THR70F, TYR56F, TYR66F, TYR7D, TYR86D, VAL129D, VAL23F
• E-F: ARG16F, ARG27F, ARG29F, ASP28F, ASP31F, GLN32F, HIS33F, ILE34F, LEU18F, LYS1E, LYS2E, PRO3E, SER30F, THR26F