3JS2

crystal structure of minimal kinase domain of fibroblast growth factor receptor 1 in complex with 5-(2-thienyl) nicotinic acid

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 58
  • Norm. En. per Res.: -1.6753
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-4.0827	-3.0955	-89.9898	-97.168	58	3	0	4300	0	30	18

Interface residues

• A-B: ALA615B, ALA671B, ARG577A, ARG622B, ARG646B, ARG675B, ASN590A, ASN724A, ASN763A, ASP599A, ASP647B, ASP674B, ASP682B, CYS619B, GLN594A, GLN680B, GLN749B, GLN764A, GLU592A, GLU593A, GLU612B, GLU670B, GLU765A, GLY580A, HIS589A, HIS649B, HIS650B, HIS679B, ILE620B, ILE648B, ILE676B, LEU581A, LEU595A, LEU614B, LEU672B, LYS598A, LYS617B, LYS618B, LYS748B, MET611B, PHE673B, PHE747B, PRO578A, PRO579A, PRO591A, PRO741B, PRO745B, SER596A, SER597A, SER616B, SER681B, SER742B, SER762A, THR678B, THR746B, TYR653B, TYR677B, VAL683B