3IZJ

mm-cpn rls with atp and alfx

• Total interactions analyzed: 120
• Total true interactions: 45
• Strongest Interaction:
  • Chains: L-M
  • Int. Res.: 243
  • Norm. En. per Res.: -3.121
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-185.8403	9.7466	-597.93	-774.0237	254	28	20	25746	9	103	125
A-C	0.0	3.2375	-2.7126	0.5249	13	0	0	279	0	5	4
A-G	0.0	3.2375	-2.7126	0.5249	13	0	0	279	0	5	4
A-H	-186.0415	9.6595	-598.506	-774.888	254	28	20	25760	9	103	125
A-I	-25.1965	-99.1985	-78.2513	-202.6464	84	6	2	4804	6	48	49
B-C	-186.0415	9.6595	-598.506	-774.888	254	28	20	25760	9	103	125
B-D	0.0	3.2374	-2.7137	0.5237	13	0	0	279	0	5	4
B-H	0.0	3.2374	-2.7137	0.5237	13	0	0	279	0	5	4
B-P	-25.2193	-99.2675			14
C-D	-185.8403	9.7466	-597.93	-774.0237	254	28	20	25746	9	103	125
C-E	0.0	3.2375	-2.7126	0.5249	13	0	0	279	0	5	4
C-O	-25.2015	-99.1978			14
D-E	-186.0415	9.6595	-598.506	-774.888	254	28	20	25760	9	103	125
D-F	0.0	3.2374	-2.7137	0.5237	13	0	0	279	0	5	4
D-M	0.0	0.0	-0.0006	-0.0006	4	0	0	2	0	4	2
D-N	-25.2193	-99.2668			14
E-F	-185.8403	9.7466	-597.93	-774.0237	254	28	20	25746	9	103	125
E-G	0.0	3.2375	-2.7126	0.5249	13	0	0	279	0	5	4
E-L	0.0	0.0	-0.0006	-0.0006	4	0	0	2	0	4	2
E-M	-25.2015	-99.1878	-31.0468	-155.4361	52	4	0	2010	4	31	34
F-G	-186.0415	9.6595	-598.506	-774.888	254	28	20	25760	9	103	125
F-H	0.0	3.2374	-2.7137	0.5237	13	0	0	279	0	5	4
F-K	0.0	0.0	-0.0006	-0.0006	4	0	0	2	0	4	2
F-L	-25.2151	-99.2666	-78.2838	-202.7655	84	6	2	4806	6	48	49
G-H	-185.8403	9.7466	-597.93	-774.0237	254	28	20	25746	9	103	125
G-J	0.0	0.0	-0.0006	-0.0006	4	0	0	2	0	4	2
G-K	-25.1965	-99.1885	-78.25	-202.635	84	6	2	4804	6	48	49
H-I	0.0	0.0	-0.0006	-0.0006	4	0	0	2	0	4	2
H-J	-25.2151	-99.2673	-78.2881	-202.7705	84	6	2	4806	6	48	49
I-J	-186.1983	9.6245	-597.786	-774.3598	254	29	20	25725	9	103	125
I-K	0.0	3.2375	-2.7752	0.4623	13	0	0	294	0	5	4
I-O	0.0	3.2375			2
I-P	-185.742	9.7823			54
J-K	-185.7031	9.7902	-596.443	-772.3559	254	29	20	25686	9	103	125
J-L	0.0	3.2369	-2.7751	0.4618	13	0	0	294	0	5	4
J-P	0.0	3.2369			2
K-L	-186.1763	9.6189	-597.783	-774.3403	254	29	20	25721	9	103	125
K-M	0.0	3.2373	-2.775	0.4623	13	0	0	294	0	5	4
L-M	-185.6829	9.8073	-582.532	-758.4076	243	29	20	25160	9	100	122
L-N	0.0	3.2377			2
M-N	-186.1715	9.6189			54
M-O	0.0	3.2373			2
N-O	-185.7217	9.7994			54
N-P	0.0	3.2377			2
O-P	-186.1935	9.6244			54

Interface residues

• A-B: ALA122A, ALA14A, ALA21A, ALA242A, ALA250A, ALA312A, ALA317A, ALA321A, ALA322A, ALA324A, ALA325A, ALA492A, ALA496A, ALA497A, ALA511A, ALA512A, ALA534B, ALA539B, ALA581B, ALA582B, ALA68A, ALA69A, ALA708B, ALA728B, ALA755B, ALA763B, ALA76A, ALA801B, ALA806B, ALA952B, ALA955B, ARG245A, ARG419A, ARG487A, ARG505A, ARG536B, ARG758B, ARG814B, ARG8A, ASN18A, ASN230A, ASN318A, ASN566B, ASN954B, ASP183A, ASP185A, ASP241A, ASP248A, ASP265A, ASP330A, ASP507A, ASP508A, ASP552B, ASP557B, ASP558B, ASP561B, ASP754B, ASP761B, ASP798B, ASP799B, CYS231A, GLN119A, GLN123A, GLN126A, GLN15A, GLN258A, GLN281A, GLN329A, GLN491A, GLN494A, GLN729B, GLN771B, GLN79A, GLN802B, GLU1026B, GLU234A, GLU237A, GLU239A, GLU243A, GLU254A, GLU257A, GLU259A, GLU260A, GLU269A, GLU309A, GLU420A, GLU498A, GLU4A, GLU501A, GLU513A, GLU540B, GLU574B, GLU578B, GLU65A, GLU671B, GLU724B, GLU747B, GLU74A, GLU750B, GLU756B, GLU767B, GLU770B, GLU772B, GLU773B, GLU82A, GLU881B, GLU885B, GLU886B, GLU953B, GLY11A, GLY535B, GLY550B, GLY560B, GLY667B, GLY669B, GLY707B, GLY857B, GLY878B, GLY956B, HIS110A, HIS579B, HIS66A, HIS803B, HIS882B, ILE113A, ILE235A, ILE244A, ILE246A, ILE256A, ILE320A, ILE323A, ILE493A, ILE506A, ILE510A, ILE537B, ILE538B, ILE571B, ILE586B, ILE710B, ILE73A, ILE748B, ILE757B, ILE759B, ILE769B, ILE855B, LEU186A, LEU228A, LEU252A, LEU263A, LEU2A, LEU326A, LEU331A, LEU503A, LEU504A, LEU533B, LEU555B, LEU559B, LEU572B, LEU72A, LEU765B, LEU776B, LEU800B, LEU951B, LEU957B, LYS116A, LYS181A, LYS184A, LYS236A, LYS251A, LYS261A, LYS282A, LYS305A, LYS313A, LYS357A, LYS520B, LYS549B, LYS553B, LYS583B, LYS668B, LYS672B, LYS70A, LYS732B, LYS749B, LYS764B, LYS77A, LYS7A, LYS807B, LYS81A, LYS854B, MET10A, MET17A, MET253A, MET262A, MET266A, MET502A, MET530B, MET551B, MET554B, MET575B, MET6A, MET71A, MET730B, MET766B, MET775B, PHE255A, PHE768B, PHE983B, PRO111A, PRO3A, PRO548B, PRO580B, PRO67A, PRO762B, SER327A, SER495A, SER499A, SER544B, SER576B, SER706B, SER709B, SER727B, SER856B, THR112A, THR238A, THR240A, THR247A, THR490A, THR541B, THR545B, THR565B, THR751B, THR760B, THR78A, THR879B, THR880B, TYR804B, TYR9A, VAL114A, VAL115A, VAL182A, VAL1A, VAL319A, VAL509A, VAL542B, VAL556B, VAL562B, VAL563B, VAL564B, VAL577B, VAL64A, VAL726B, VAL75A, VAL883B, VAL982B
• A-C: ALA242A, ARG1271C, ARG245A, ASP241A, GLU239A, GLU243A, ILE1272C, ILE1282C, LEU1278C, MET1279C, THR1273C, THR238A, THR240A
• A-G: ALA3320G, ARG245A, ARG3323G, ASP3319G, GLU3317G, GLU3321G, ILE246A, ILE256A, LEU252A, MET253A, THR247A, THR3316G, THR3318G
• A-H: ALA195A, ALA215A, ALA21A, ALA242A, ALA250A, ALA26A, ALA288A, ALA293A, ALA3605H, ALA3612H, ALA3659H, ALA3660H, ALA3667H, ALA3713H, ALA3833H, ALA3841H, ALA3903H, ALA3908H, ALA3912H, ALA3913H, ALA3915H, ALA3916H, ALA4083H, ALA4087H, ALA4088H, ALA4102H, ALA4103H, ALA439A, ALA442A, ALA68A, ALA69A, ARG23A, ARG245A, ARG301A, ARG3599H, ARG3836H, ARG4010H, ARG4078H, ARG4096H, ASN3609H, ASN3821H, ASN3909H, ASN441A, ASN53A, ASP241A, ASP248A, ASP285A, ASP286A, ASP3774H, ASP3776H, ASP3832H, ASP3839H, ASP3856H, ASP3921H, ASP39A, ASP4098H, ASP4099H, ASP44A, ASP45A, ASP48A, CYS3822H, GLN216A, GLN258A, GLN289A, GLN3606H, GLN3670H, GLN3710H, GLN3714H, GLN3717H, GLN3849H, GLN3872H, GLN3920H, GLN4082H, GLN4085H, GLU158A, GLU211A, GLU234A, GLU237A, GLU243A, GLU254A, GLU257A, GLU259A, GLU260A, GLU27A, GLU3595H, GLU3656H, GLU3665H, GLU3673H, GLU368A, GLU372A, GLU373A, GLU3825H, GLU3828H, GLU3830H, GLU3834H, GLU3845H, GLU3848H, GLU3850H, GLU3851H, GLU3860H, GLU3900H, GLU4011H, GLU4089H, GLU4092H, GLU4104H, GLU440A, GLU513A, GLU61A, GLU65A, GLY154A, GLY156A, GLY194A, GLY22A, GLY344A, GLY3602H, GLY365A, GLY37A, GLY443A, GLY47A, HIS290A, HIS3657H, HIS369A, HIS3701H, HIS66A, ILE197A, ILE235A, ILE244A, ILE246A, ILE24A, ILE256A, ILE25A, ILE342A, ILE3664H, ILE3704H, ILE3826H, ILE3835H, ILE3837H, ILE3847H, ILE3911H, ILE3914H, ILE4084H, ILE4097H, ILE4101H, ILE58A, ILE73A, LEU20A, LEU252A, LEU263A, LEU287A, LEU3593H, LEU3663H, LEU3777H, LEU3819H, LEU3843H, LEU3854H, LEU3917H, LEU3922H, LEU4094H, LEU4095H, LEU42A, LEU438A, LEU444A, LEU46A, LEU59A, LYS155A, LYS159A, LYS219A, LYS236A, LYS251A, LYS294A, LYS341A, LYS3598H, LYS3661H, LYS3668H, LYS3672H, LYS36A, LYS3707H, LYS3772H, LYS3775H, LYS3827H, LYS3842H, LYS3852H, LYS3873H, LYS3896H, LYS3904H, LYS3948H, LYS40A, LYS70A, LYS7A, MET17A, MET217A, MET253A, MET262A, MET3597H, MET3601H, MET3608H, MET3662H, MET3844H, MET3853H, MET3857H, MET38A, MET4093H, MET41A, MET62A, PHE255A, PHE3846H, PHE470A, PRO249A, PRO3594H, PRO35A, PRO3658H, PRO3702H, PRO67A, SER193A, SER196A, SER214A, SER31A, SER343A, SER3918H, SER4086H, SER4090H, SER63A, THR238A, THR247A, THR28A, THR32A, THR3669H, THR366A, THR367A, THR3703H, THR3829H, THR3831H, THR3838H, THR4081H, THR52A, TYR291A, TYR3600H, VAL213A, VAL29A, VAL3592H, VAL3655H, VAL3666H, VAL3705H, VAL3706H, VAL370A, VAL3773H, VAL3910H, VAL4100H, VAL43A, VAL469A, VAL49A, VAL50A, VAL51A, VAL64A
• A-I: ALA423A, ALA439A, ALA446A, ALA4527I, ALA4543I, ALA4550I, ARG12A, ARG16A, ARG23A, ARG30A, ARG4116I, ARG4120I, ARG4127I, ARG4134I, ARG419A, ARG4203I, ARG425A, ARG436A, ARG4523I, ARG4529I, ARG4540I, ARG99A, ASN108A, ASN4212I, ASN441A, ASN4545I, ASP106A, ASP4210I, ASP445A, ASP4549I, GLN107A, GLN4211I, GLN421A, GLN4525I, GLU102A, GLU103A, GLU27A, GLU4131I, GLU4200I, GLU4206I, GLU4207I, GLU420A, GLU432A, GLU440A, GLU448A, GLU4524I, GLU4536I, GLU4544I, GLU4552I, GLU96A, GLY418A, GLY443A, GLY4522I, GLY4547I, HIS110A, HIS4214I, ILE113A, ILE24A, ILE4128I, ILE4217I, ILE447A, ILE4551I, LEU104A, LEU105A, LEU20A, LEU4124I, LEU4208I, LEU4209I, LEU422A, LEU444A, LEU450A, LEU4526I, LEU4548I, LEU4554I, LYS100A, LYS4204I, SER417A, SER4521I, VAL109A, VAL4213I, VAL433A, VAL451A, VAL4537I, VAL4555I
• B-C: ALA1005B, ALA1009B, ALA1010B, ALA1024B, ALA1025B, ALA1047C, ALA1052C, ALA1094C, ALA1095C, ALA1221C, ALA1241C, ALA1268C, ALA1276C, ALA1314C, ALA1319C, ALA1465C, ALA1468C, ALA527B, ALA534B, ALA581B, ALA582B, ALA589B, ALA635B, ALA755B, ALA763B, ALA825B, ALA830B, ALA834B, ALA835B, ALA837B, ALA838B, ARG1000B, ARG1018B, ARG1049C, ARG1271C, ARG1327C, ARG521B, ARG758B, ARG932B, ASN1079C, ASN1467C, ASN531B, ASN743B, ASN831B, ASP1020B, ASP1021B, ASP1065C, ASP1070C, ASP1071C, ASP1074C, ASP1267C, ASP1274C, ASP1311C, ASP1312C, ASP696B, ASP698B, ASP754B, ASP761B, ASP778B, ASP843B, CYS744B, GLN1004B, GLN1007B, GLN1242C, GLN1284C, GLN1315C, GLN528B, GLN592B, GLN632B, GLN636B, GLN639B, GLN771B, GLN794B, GLN842B, GLU1011B, GLU1014B, GLU1026B, GLU1053C, GLU1087C, GLU1091C, GLU1184C, GLU1237C, GLU1260C, GLU1263C, GLU1269C, GLU1280C, GLU1283C, GLU1285C, GLU1286C, GLU1394C, GLU1398C, GLU1399C, GLU1466C, GLU1539C, GLU517B, GLU578B, GLU587B, GLU595B, GLU747B, GLU750B, GLU752B, GLU756B, GLU767B, GLU770B, GLU772B, GLU773B, GLU782B, GLU822B, GLU933B, GLY1048C, GLY1063C, GLY1073C, GLY1180C, GLY1182C, GLY1220C, GLY1370C, GLY1391C, GLY1469C, GLY524B, HIS1092C, HIS1316C, HIS1395C, HIS579B, HIS623B, ILE1006B, ILE1019B, ILE1023B, ILE1050C, ILE1051C, ILE1084C, ILE1099C, ILE1223C, ILE1261C, ILE1270C, ILE1272C, ILE1282C, ILE1368C, ILE586B, ILE626B, ILE748B, ILE757B, ILE759B, ILE769B, ILE833B, ILE836B, LEU1016B, LEU1017B, LEU1046C, LEU1068C, LEU1072C, LEU1085C, LEU1278C, LEU1289C, LEU1313C, LEU1464C, LEU1470C, LEU515B, LEU585B, LEU699B, LEU741B, LEU765B, LEU776B, LEU839B, LEU844B, LYS1033C, LYS1062C, LYS1066C, LYS1096C, LYS1181C, LYS1185C, LYS1245C, LYS1262C, LYS1277C, LYS1320C, LYS1367C, LYS520B, LYS583B, LYS590B, LYS594B, LYS629B, LYS694B, LYS697B, LYS749B, LYS764B, LYS774B, LYS795B, LYS818B, LYS826B, LYS870B, MET1015B, MET1043C, MET1064C, MET1067C, MET1088C, MET1243C, MET1279C, MET1288C, MET519B, MET523B, MET530B, MET584B, MET766B, MET775B, MET779B, PHE1281C, PHE1496C, PHE768B, PRO1061C, PRO1093C, PRO1275C, PRO516B, PRO580B, PRO624B, SER1008B, SER1012B, SER1057C, SER1089C, SER1219C, SER1222C, SER1240C, SER1369C, SER840B, THR1003B, THR1054C, THR1058C, THR1078C, THR1264C, THR1273C, THR1392C, THR1393C, THR591B, THR625B, THR751B, THR753B, THR760B, TYR1317C, TYR522B, VAL1022B, VAL1055C, VAL1069C, VAL1075C, VAL1076C, VAL1077C, VAL1090C, VAL1239C, VAL1396C, VAL1495C, VAL514B, VAL577B, VAL588B, VAL627B, VAL628B, VAL695B, VAL832B
• B-D: ALA755B, ARG1784D, ARG758B, ASP754B, GLU752B, GLU756B, ILE1785D, ILE1795D, LEU1791D, MET1792D, THR1786D, THR751B, THR753B
• B-H: ALA3833H, ARG3836H, ARG758B, ASP3832H, GLU3830H, GLU3834H, ILE759B, ILE769B, LEU765B, MET766B, THR3829H, THR3831H, THR760B
• B-P: ARG612B, ARG7794P, ARG8114P, ARG932B, ASP619B, ASP7801P, ASP8140P, ASP958B, GLU540B, GLU616B, GLU7722P, GLU7798P, GLU8143P, GLU961B
• C-D: ALA1040C, ALA1047C, ALA1094C, ALA1095C, ALA1102C, ALA1148C, ALA1268C, ALA1276C, ALA1338C, ALA1343C, ALA1347C, ALA1348C, ALA1350C, ALA1351C, ALA1518C, ALA1522C, ALA1523C, ALA1537C, ALA1538C, ALA1560D, ALA1565D, ALA1607D, ALA1608D, ALA1734D, ALA1754D, ALA1781D, ALA1789D, ALA1827D, ALA1832D, ALA1978D, ALA1981D, ARG1034C, ARG1271C, ARG1445C, ARG1513C, ARG1531C, ARG1562D, ARG1784D, ARG1840D, ASN1044C, ASN1256C, ASN1344C, ASN1592D, ASN1980D, ASP1209C, ASP1211C, ASP1267C, ASP1274C, ASP1291C, ASP1356C, ASP1533C, ASP1534C, ASP1578D, ASP1583D, ASP1584D, ASP1587D, ASP1780D, ASP1787D, ASP1824D, ASP1825D, CYS1257C, GLN1041C, GLN1105C, GLN1145C, GLN1149C, GLN1152C, GLN1284C, GLN1307C, GLN1355C, GLN1517C, GLN1520C, GLN1755D, GLN1797D, GLN1828D, GLU1030C, GLU1091C, GLU1100C, GLU1108C, GLU1260C, GLU1263C, GLU1265C, GLU1269C, GLU1280C, GLU1283C, GLU1285C, GLU1286C, GLU1295C, GLU1335C, GLU1446C, GLU1524C, GLU1527C, GLU1539C, GLU1566D, GLU1600D, GLU1604D, GLU1697D, GLU1750D, GLU1773D, GLU1776D, GLU1782D, GLU1793D, GLU1796D, GLU1798D, GLU1799D, GLU1907D, GLU1911D, GLU1912D, GLU1979D, GLU2052D, GLY1037C, GLY1561D, GLY1576D, GLY1586D, GLY1693D, GLY1695D, GLY1733D, GLY1883D, GLY1904D, GLY1982D, HIS1092C, HIS1136C, HIS1605D, HIS1829D, HIS1908D, ILE1099C, ILE1139C, ILE1261C, ILE1270C, ILE1272C, ILE1282C, ILE1346C, ILE1349C, ILE1519C, ILE1532C, ILE1536C, ILE1563D, ILE1564D, ILE1597D, ILE1612D, ILE1736D, ILE1774D, ILE1783D, ILE1785D, ILE1795D, ILE1881D, LEU1028C, LEU1098C, LEU1212C, LEU1254C, LEU1278C, LEU1289C, LEU1352C, LEU1357C, LEU1529C, LEU1530C, LEU1559D, LEU1581D, LEU1585D, LEU1598D, LEU1791D, LEU1802D, LEU1826D, LEU1977D, LEU1983D, LYS1033C, LYS1096C, LYS1103C, LYS1107C, LYS1142C, LYS1207C, LYS1210C, LYS1262C, LYS1277C, LYS1287C, LYS1308C, LYS1331C, LYS1339C, LYS1383C, LYS1546D, LYS1575D, LYS1579D, LYS1609D, LYS1694D, LYS1698D, LYS1758D, LYS1775D, LYS1790D, LYS1833D, LYS1880D, MET1032C, MET1036C, MET1043C, MET1097C, MET1279C, MET1288C, MET1292C, MET1528C, MET1556D, MET1577D, MET1580D, MET1601D, MET1756D, MET1792D, MET1801D, PHE1281C, PHE1794D, PHE2009D, PRO1029C, PRO1093C, PRO1137C, PRO1574D, PRO1606D, PRO1788D, SER1353C, SER1521C, SER1525C, SER1570D, SER1602D, SER1732D, SER1735D, SER1753D, SER1882D, THR1104C, THR1138C, THR1264C, THR1266C, THR1273C, THR1516C, THR1567D, THR1571D, THR1591D, THR1777D, THR1786D, THR1905D, THR1906D, TYR1035C, TYR1830D, VAL1027C, VAL1090C, VAL1101C, VAL1140C, VAL1141C, VAL1208C, VAL1345C, VAL1535C, VAL1568D, VAL1582D, VAL1588D, VAL1589D, VAL1590D, VAL1603D, VAL1752D, VAL1909D, VAL2008D
• C-E: ALA1268C, ARG1271C, ARG2297E, ASP1267C, GLU1265C, GLU1269C, ILE2298E, ILE2308E, LEU2304E, MET2305E, THR1264C, THR1266C, THR2299E
• C-O: ARG1125C, ARG1445C, ARG7281O, ARG7601O, ASP1132C, ASP1471C, ASP7288O, ASP7627O, GLU1053C, GLU1129C, GLU1474C, GLU7209O, GLU7285O, GLU7630O
• D-E: ALA1553D, ALA1560D, ALA1607D, ALA1608D, ALA1615D, ALA1661D, ALA1781D, ALA1789D, ALA1851D, ALA1856D, ALA1860D, ALA1861D, ALA1863D, ALA1864D, ALA2031D, ALA2035D, ALA2036D, ALA2050D, ALA2051D, ALA2073E, ALA2078E, ALA2120E, ALA2121E, ALA2247E, ALA2267E, ALA2294E, ALA2302E, ALA2340E, ALA2345E, ALA2491E, ALA2494E, ARG1547D, ARG1784D, ARG1958D, ARG2026D, ARG2044D, ARG2075E, ARG2297E, ARG2353E, ASN1557D, ASN1769D, ASN1857D, ASN2105E, ASN2493E, ASP1722D, ASP1724D, ASP1780D, ASP1787D, ASP1804D, ASP1869D, ASP2046D, ASP2047D, ASP2091E, ASP2096E, ASP2097E, ASP2100E, ASP2293E, ASP2300E, ASP2337E, ASP2338E, CYS1770D, GLN1554D, GLN1618D, GLN1658D, GLN1662D, GLN1665D, GLN1797D, GLN1820D, GLN1868D, GLN2030D, GLN2033D, GLN2268E, GLN2310E, GLN2341E, GLU1543D, GLU1604D, GLU1613D, GLU1621D, GLU1773D, GLU1776D, GLU1778D, GLU1782D, GLU1793D, GLU1796D, GLU1798D, GLU1799D, GLU1808D, GLU1848D, GLU1959D, GLU2037D, GLU2040D, GLU2052D, GLU2079E, GLU2113E, GLU2117E, GLU2210E, GLU2263E, GLU2286E, GLU2289E, GLU2295E, GLU2306E, GLU2309E, GLU2311E, GLU2312E, GLU2420E, GLU2424E, GLU2425E, GLU2492E, GLU2565E, GLY1550D, GLY2074E, GLY2089E, GLY2099E, GLY2206E, GLY2208E, GLY2246E, GLY2396E, GLY2417E, GLY2495E, HIS1605D, HIS1649D, HIS2118E, HIS2342E, HIS2421E, ILE1612D, ILE1652D, ILE1774D, ILE1783D, ILE1785D, ILE1795D, ILE1859D, ILE1862D, ILE2032D, ILE2045D, ILE2049D, ILE2076E, ILE2077E, ILE2110E, ILE2125E, ILE2249E, ILE2287E, ILE2296E, ILE2298E, ILE2308E, ILE2394E, LEU1541D, LEU1611D, LEU1725D, LEU1767D, LEU1791D, LEU1802D, LEU1865D, LEU1870D, LEU2042D, LEU2043D, LEU2072E, LEU2094E, LEU2098E, LEU2111E, LEU2304E, LEU2315E, LEU2339E, LEU2490E, LEU2496E, LYS1546D, LYS1609D, LYS1616D, LYS1620D, LYS1655D, LYS1720D, LYS1723D, LYS1775D, LYS1790D, LYS1800D, LYS1821D, LYS1844D, LYS1852D, LYS1896D, LYS2059E, LYS2088E, LYS2092E, LYS2122E, LYS2207E, LYS2211E, LYS2271E, LYS2288E, LYS2303E, LYS2346E, LYS2393E, MET1545D, MET1549D, MET1556D, MET1610D, MET1792D, MET1801D, MET1805D, MET2041D, MET2069E, MET2090E, MET2093E, MET2114E, MET2269E, MET2305E, MET2314E, PHE1794D, PHE2307E, PHE2522E, PRO1542D, PRO1606D, PRO1650D, PRO2087E, PRO2119E, PRO2301E, SER1866D, SER2034D, SER2038D, SER2083E, SER2115E, SER2245E, SER2248E, SER2266E, SER2395E, THR1617D, THR1651D, THR1777D, THR1779D, THR1786D, THR2029D, THR2080E, THR2084E, THR2104E, THR2290E, THR2299E, THR2418E, THR2419E, TYR1548D, TYR2343E, VAL1540D, VAL1603D, VAL1614D, VAL1653D, VAL1654D, VAL1721D, VAL1858D, VAL2048D, VAL2081E, VAL2095E, VAL2101E, VAL2102E, VAL2103E, VAL2116E, VAL2265E, VAL2422E, VAL2521E
• D-F: ALA1781D, ARG1784D, ARG2810F, ASP1780D, GLU1778D, GLU1782D, ILE2811F, ILE2821F, LEU2817F, MET2818F, THR1777D, THR1779D, THR2812F
• D-M: ASN1647D, ASN6264M, HIS1649D, HIS6266M
• D-N: ARG1638D, ARG1958D, ARG6768N, ARG7088N, ASP1645D, ASP1984D, ASP6775N, ASP7114N, GLU1566D, GLU1642D, GLU1987D, GLU6696N, GLU6772N, GLU7117N
• E-F: ALA2066E, ALA2073E, ALA2120E, ALA2121E, ALA2128E, ALA2174E, ALA2294E, ALA2302E, ALA2364E, ALA2369E, ALA2373E, ALA2374E, ALA2376E, ALA2377E, ALA2544E, ALA2548E, ALA2549E, ALA2563E, ALA2564E, ALA2586F, ALA2591F, ALA2633F, ALA2634F, ALA2760F, ALA2780F, ALA2807F, ALA2815F, ALA2853F, ALA2858F, ALA3004F, ALA3007F, ARG2060E, ARG2297E, ARG2471E, ARG2539E, ARG2557E, ARG2588F, ARG2810F, ARG2866F, ASN2070E, ASN2282E, ASN2370E, ASN2618F, ASN3006F, ASP2235E, ASP2237E, ASP2293E, ASP2300E, ASP2317E, ASP2382E, ASP2559E, ASP2560E, ASP2604F, ASP2609F, ASP2610F, ASP2613F, ASP2806F, ASP2813F, ASP2850F, ASP2851F, CYS2283E, GLN2067E, GLN2131E, GLN2171E, GLN2175E, GLN2178E, GLN2310E, GLN2333E, GLN2381E, GLN2543E, GLN2546E, GLN2781F, GLN2823F, GLN2854F, GLU2056E, GLU2117E, GLU2126E, GLU2134E, GLU2286E, GLU2289E, GLU2291E, GLU2295E, GLU2306E, GLU2309E, GLU2311E, GLU2312E, GLU2321E, GLU2361E, GLU2472E, GLU2550E, GLU2553E, GLU2565E, GLU2592F, GLU2626F, GLU2630F, GLU2723F, GLU2776F, GLU2799F, GLU2802F, GLU2808F, GLU2819F, GLU2822F, GLU2824F, GLU2825F, GLU2933F, GLU2937F, GLU2938F, GLU3005F, GLU3078F, GLY2063E, GLY2587F, GLY2602F, GLY2612F, GLY2719F, GLY2721F, GLY2759F, GLY2909F, GLY2930F, GLY3008F, HIS2118E, HIS2162E, HIS2631F, HIS2855F, HIS2934F, ILE2125E, ILE2165E, ILE2287E, ILE2296E, ILE2298E, ILE2308E, ILE2372E, ILE2375E, ILE2545E, ILE2558E, ILE2562E, ILE2589F, ILE2590F, ILE2623F, ILE2638F, ILE2762F, ILE2800F, ILE2809F, ILE2811F, ILE2821F, ILE2907F, LEU2054E, LEU2124E, LEU2238E, LEU2280E, LEU2304E, LEU2315E, LEU2378E, LEU2383E, LEU2555E, LEU2556E, LEU2585F, LEU2607F, LEU2611F, LEU2624F, LEU2817F, LEU2828F, LEU2852F, LEU3003F, LEU3009F, LYS2059E, LYS2122E, LYS2129E, LYS2133E, LYS2168E, LYS2233E, LYS2236E, LYS2288E, LYS2303E, LYS2313E, LYS2334E, LYS2357E, LYS2365E, LYS2409E, LYS2572F, LYS2601F, LYS2605F, LYS2635F, LYS2720F, LYS2724F, LYS2784F, LYS2801F, LYS2816F, LYS2859F, LYS2906F, MET2058E, MET2062E, MET2069E, MET2123E, MET2305E, MET2314E, MET2318E, MET2554E, MET2582F, MET2603F, MET2606F, MET2627F, MET2782F, MET2818F, MET2827F, PHE2307E, PHE2820F, PHE3035F, PRO2055E, PRO2119E, PRO2163E, PRO2600F, PRO2632F, PRO2814F, SER2379E, SER2547E, SER2551E, SER2596F, SER2628F, SER2758F, SER2761F, SER2779F, SER2908F, THR2130E, THR2164E, THR2290E, THR2292E, THR2299E, THR2542E, THR2593F, THR2597F, THR2617F, THR2803F, THR2812F, THR2931F, THR2932F, TYR2061E, TYR2856F, VAL2053E, VAL2116E, VAL2127E, VAL2166E, VAL2167E, VAL2234E, VAL2371E, VAL2561E, VAL2594F, VAL2608F, VAL2614F, VAL2615F, VAL2616F, VAL2629F, VAL2778F, VAL2935F, VAL3034F
• E-G: ALA2294E, ARG2297E, ARG3323G, ASP2293E, GLU2291E, GLU2295E, ILE3324G, ILE3334G, LEU3330G, MET3331G, THR2290E, THR2292E, THR3325G
• E-L: ASN2160E, ASN5751L, HIS2162E, HIS5753L
• E-M: ALA2491E, ALA2498E, ARG2064E, ARG2068E, ARG2075E, ARG2082E, ARG2151E, ARG2471E, ARG2488E, ARG6168M, ARG6172M, ARG6179M, ARG6186M, ARG6255M, ARG6575M, ASN2160E, ASN2493E, ASN6264M, ASP2158E, ASP2497E, ASP6262M, ASP6601M, GLN2159E, GLN6263M, GLU2079E, GLU2148E, GLU2154E, GLU2155E, GLU2484E, GLU2492E, GLU2500E, GLU6183M, GLU6252M, GLU6258M, GLU6259M, GLU6604M, GLY2495E, HIS6266M, ILE2076E, ILE2499E, ILE6180M, ILE6269M, LEU2072E, LEU2496E, LEU2502E, LEU6176M, LEU6260M, LEU6261M, LYS2152E, LYS6256M, VAL2485E, VAL6265M
• F-G: ALA2579F, ALA2586F, ALA2633F, ALA2634F, ALA2641F, ALA2687F, ALA2807F, ALA2815F, ALA2877F, ALA2882F, ALA2886F, ALA2887F, ALA2889F, ALA2890F, ALA3057F, ALA3061F, ALA3062F, ALA3076F, ALA3077F, ALA3099G, ALA3104G, ALA3146G, ALA3147G, ALA3273G, ALA3293G, ALA3320G, ALA3328G, ALA3366G, ALA3371G, ALA3517G, ALA3520G, ARG2573F, ARG2810F, ARG2984F, ARG3052F, ARG3070F, ARG3101G, ARG3323G, ARG3379G, ASN2583F, ASN2795F, ASN2883F, ASN3131G, ASN3519G, ASP2748F, ASP2750F, ASP2806F, ASP2813F, ASP2830F, ASP2895F, ASP3072F, ASP3073F, ASP3117G, ASP3122G, ASP3123G, ASP3126G, ASP3319G, ASP3326G, ASP3363G, ASP3364G, CYS2796F, GLN2580F, GLN2644F, GLN2684F, GLN2688F, GLN2691F, GLN2823F, GLN2846F, GLN2894F, GLN3056F, GLN3059F, GLN3294G, GLN3336G, GLN3367G, GLU2569F, GLU2630F, GLU2639F, GLU2647F, GLU2799F, GLU2802F, GLU2804F, GLU2808F, GLU2819F, GLU2822F, GLU2824F, GLU2825F, GLU2834F, GLU2874F, GLU2985F, GLU3063F, GLU3066F, GLU3078F, GLU3105G, GLU3139G, GLU3143G, GLU3236G, GLU3289G, GLU3312G, GLU3315G, GLU3321G, GLU3332G, GLU3335G, GLU3337G, GLU3338G, GLU3446G, GLU3450G, GLU3451G, GLU3518G, GLU3591G, GLY2576F, GLY3100G, GLY3115G, GLY3125G, GLY3232G, GLY3234G, GLY3272G, GLY3422G, GLY3443G, GLY3521G, HIS2631F, HIS2675F, HIS3144G, HIS3368G, HIS3447G, ILE2638F, ILE2678F, ILE2800F, ILE2809F, ILE2811F, ILE2821F, ILE2885F, ILE2888F, ILE3058F, ILE3071F, ILE3075F, ILE3102G, ILE3103G, ILE3136G, ILE3151G, ILE3275G, ILE3313G, ILE3322G, ILE3324G, ILE3334G, ILE3420G, LEU2567F, LEU2637F, LEU2751F, LEU2793F, LEU2817F, LEU2828F, LEU2891F, LEU2896F, LEU3068F, LEU3069F, LEU3098G, LEU3120G, LEU3124G, LEU3137G, LEU3330G, LEU3341G, LEU3365G, LEU3516G, LEU3522G, LYS2572F, LYS2635F, LYS2642F, LYS2646F, LYS2681F, LYS2746F, LYS2749F, LYS2801F, LYS2816F, LYS2826F, LYS2847F, LYS2870F, LYS2878F, LYS2922F, LYS3085G, LYS3114G, LYS3118G, LYS3148G, LYS3233G, LYS3237G, LYS3297G, LYS3314G, LYS3329G, LYS3372G, LYS3419G, MET2571F, MET2575F, MET2582F, MET2636F, MET2818F, MET2827F, MET2831F, MET3067F, MET3095G, MET3116G, MET3119G, MET3140G, MET3295G, MET3331G, MET3340G, PHE2820F, PHE3333G, PHE3548G, PRO2568F, PRO2632F, PRO2676F, PRO3113G, PRO3145G, PRO3327G, SER2892F, SER3060F, SER3064F, SER3109G, SER3141G, SER3271G, SER3274G, SER3292G, SER3421G, THR2643F, THR2677F, THR2803F, THR2805F, THR2812F, THR3055F, THR3106G, THR3110G, THR3130G, THR3316G, THR3325G, THR3444G, THR3445G, TYR2574F, TYR3369G, VAL2566F, VAL2629F, VAL2640F, VAL2679F, VAL2680F, VAL2747F, VAL2884F, VAL3074F, VAL3107G, VAL3121G, VAL3127G, VAL3128G, VAL3129G, VAL3142G, VAL3291G, VAL3448G, VAL3547G
• F-H: ALA2807F, ARG2810F, ARG3836H, ASP2806F, GLU2804F, GLU2808F, ILE3837H, ILE3847H, LEU3843H, MET3844H, THR2803F, THR2805F, THR3838H
• F-K: ASN2673F, ASN5238K, HIS2675F, HIS5240K
• F-L: ALA2988F, ALA3004F, ALA3011F, ALA6066L, ALA6082L, ALA6089L, ARG2577F, ARG2581F, ARG2588F, ARG2595F, ARG2664F, ARG2984F, ARG2990F, ARG3001F, ARG5655L, ARG5659L, ARG5666L, ARG5673L, ARG5742L, ARG6062L, ARG6068L, ARG6079L, ASN2673F, ASN3006F, ASN5751L, ASN6084L, ASP2671F, ASP3010F, ASP5749L, ASP6088L, GLN2672F, GLN2986F, GLN5750L, GLN6064L, GLU2592F, GLU2661F, GLU2667F, GLU2668F, GLU2985F, GLU2997F, GLU3005F, GLU3013F, GLU5670L, GLU5739L, GLU5745L, GLU5746L, GLU6063L, GLU6075L, GLU6083L, GLU6091L, GLY2983F, GLY3008F, GLY6061L, GLY6086L, HIS2675F, HIS5753L, ILE2589F, ILE2678F, ILE3012F, ILE5667L, ILE5756L, ILE6090L, LEU2585F, LEU2669F, LEU2670F, LEU2987F, LEU3009F, LEU3015F, LEU5663L, LEU5747L, LEU5748L, LEU6065L, LEU6087L, LEU6093L, LYS2665F, LYS5743L, SER2982F, SER6060L, VAL2674F, VAL2998F, VAL3016F, VAL5752L, VAL6076L, VAL6094L
• G-H: ALA3092G, ALA3099G, ALA3146G, ALA3147G, ALA3154G, ALA3200G, ALA3320G, ALA3328G, ALA3390G, ALA3395G, ALA3399G, ALA3400G, ALA3402G, ALA3403G, ALA3570G, ALA3574G, ALA3575G, ALA3589G, ALA3590G, ALA3612H, ALA3617H, ALA3659H, ALA3660H, ALA3786H, ALA3806H, ALA3833H, ALA3841H, ALA3879H, ALA3884H, ALA4030H, ALA4033H, ARG3086G, ARG3323G, ARG3497G, ARG3565G, ARG3583G, ARG3614H, ARG3836H, ARG3892H, ASN3096G, ASN3308G, ASN3396G, ASN3644H, ASN4032H, ASP3261G, ASP3263G, ASP3319G, ASP3326G, ASP3343G, ASP3408G, ASP3585G, ASP3586G, ASP3630H, ASP3635H, ASP3636H, ASP3639H, ASP3832H, ASP3839H, ASP3876H, ASP3877H, CYS3309G, GLN3093G, GLN3157G, GLN3197G, GLN3201G, GLN3204G, GLN3336G, GLN3359G, GLN3407G, GLN3569G, GLN3572G, GLN3807H, GLN3849H, GLN3880H, GLU3082G, GLU3143G, GLU3152G, GLU3160G, GLU3312G, GLU3315G, GLU3317G, GLU3321G, GLU3332G, GLU3335G, GLU3337G, GLU3338G, GLU3347G, GLU3387G, GLU3498G, GLU3576G, GLU3579G, GLU3591G, GLU3618H, GLU3652H, GLU3656H, GLU3749H, GLU3802H, GLU3825H, GLU3828H, GLU3834H, GLU3845H, GLU3848H, GLU3850H, GLU3851H, GLU3959H, GLU3963H, GLU3964H, GLU4031H, GLU4104H, GLY3089G, GLY3613H, GLY3628H, GLY3638H, GLY3745H, GLY3747H, GLY3785H, GLY3935H, GLY3956H, GLY4034H, HIS3144G, HIS3188G, HIS3657H, HIS3881H, HIS3960H, ILE3151G, ILE3191G, ILE3313G, ILE3322G, ILE3324G, ILE3334G, ILE3398G, ILE3401G, ILE3571G, ILE3584G, ILE3588G, ILE3615H, ILE3616H, ILE3649H, ILE3664H, ILE3788H, ILE3826H, ILE3835H, ILE3837H, ILE3847H, ILE3933H, LEU3080G, LEU3150G, LEU3264G, LEU3306G, LEU3330G, LEU3341G, LEU3404G, LEU3409G, LEU3581G, LEU3582G, LEU3611H, LEU3633H, LEU3637H, LEU3650H, LEU3843H, LEU3854H, LEU3878H, LEU4029H, LEU4035H, LYS3085G, LYS3148G, LYS3155G, LYS3159G, LYS3194G, LYS3259G, LYS3262G, LYS3314G, LYS3329G, LYS3339G, LYS3360G, LYS3383G, LYS3391G, LYS3435G, LYS3598H, LYS3627H, LYS3631H, LYS3661H, LYS3746H, LYS3750H, LYS3810H, LYS3827H, LYS3842H, LYS3885H, LYS3932H, MET3084G, MET3088G, MET3095G, MET3149G, MET3331G, MET3340G, MET3344G, MET3580G, MET3608H, MET3629H, MET3632H, MET3653H, MET3808H, MET3844H, MET3853H, PHE3333G, PHE3846H, PHE4061H, PRO3081G, PRO3145G, PRO3189G, PRO3626H, PRO3658H, PRO3840H, SER3405G, SER3573G, SER3577G, SER3622H, SER3654H, SER3784H, SER3787H, SER3805H, SER3934H, THR3156G, THR3190G, THR3316G, THR3318G, THR3325G, THR3568G, THR3619H, THR3623H, THR3643H, THR3829H, THR3838H, THR3957H, THR3958H, TYR3087G, TYR3882H, VAL3079G, VAL3142G, VAL3153G, VAL3192G, VAL3193G, VAL3260G, VAL3397G, VAL3587G, VAL3620H, VAL3634H, VAL3640H, VAL3641H, VAL3642H, VAL3655H, VAL3804H, VAL3961H, VAL4060H
• G-J: ASN3186G, ASN4725J, HIS3188G, HIS4727J
• G-K: ALA3501G, ALA3517G, ALA3524G, ALA5553K, ALA5569K, ALA5576K, ARG3090G, ARG3094G, ARG3101G, ARG3108G, ARG3177G, ARG3497G, ARG3503G, ARG3514G, ARG5142K, ARG5146K, ARG5153K, ARG5160K, ARG5229K, ARG5549K, ARG5555K, ARG5566K, ASN3186G, ASN3519G, ASN5238K, ASN5571K, ASP3184G, ASP3523G, ASP5236K, ASP5575K, GLN3185G, GLN3499G, GLN5237K, GLN5551K, GLU3105G, GLU3174G, GLU3180G, GLU3181G, GLU3498G, GLU3510G, GLU3518G, GLU3526G, GLU5157K, GLU5226K, GLU5232K, GLU5233K, GLU5550K, GLU5562K, GLU5570K, GLU5578K, GLY3496G, GLY3521G, GLY5548K, GLY5573K, HIS3188G, HIS5240K, ILE3102G, ILE3191G, ILE3525G, ILE5154K, ILE5243K, ILE5577K, LEU3098G, LEU3182G, LEU3183G, LEU3500G, LEU3522G, LEU3528G, LEU5150K, LEU5234K, LEU5235K, LEU5552K, LEU5574K, LEU5580K, LYS3178G, LYS5230K, SER3495G, SER5547K, VAL3187G, VAL3511G, VAL3529G, VAL5239K, VAL5563K, VAL5581K
• H-I: ASN3699H, ASN4212I, HIS3701H, HIS4214I
• H-J: ALA4014H, ALA4030H, ALA4037H, ALA5040J, ALA5056J, ALA5063J, ARG3603H, ARG3607H, ARG3614H, ARG3621H, ARG3690H, ARG4010H, ARG4016H, ARG4027H, ARG4629J, ARG4633J, ARG4640J, ARG4647J, ARG4716J, ARG5036J, ARG5042J, ARG5053J, ASN3699H, ASN4032H, ASN4725J, ASN5058J, ASP3697H, ASP4036H, ASP4723J, ASP5062J, GLN3698H, GLN4012H, GLN4724J, GLN5038J, GLU3618H, GLU3687H, GLU3693H, GLU3694H, GLU4011H, GLU4023H, GLU4031H, GLU4039H, GLU4644J, GLU4713J, GLU4719J, GLU4720J, GLU5037J, GLU5049J, GLU5057J, GLU5065J, GLY4009H, GLY4034H, GLY5035J, GLY5060J, HIS3701H, HIS4727J, ILE3615H, ILE3704H, ILE4038H, ILE4641J, ILE4730J, ILE5064J, LEU3611H, LEU3695H, LEU3696H, LEU4013H, LEU4035H, LEU4041H, LEU4637J, LEU4721J, LEU4722J, LEU5039J, LEU5061J, LEU5067J, LYS3691H, LYS4717J, SER4008H, SER5034J, VAL3700H, VAL4024H, VAL4042H, VAL4726J, VAL5050J, VAL5068J
• I-J: ALA4118I, ALA4125I, ALA4172I, ALA4173I, ALA4180I, ALA4226I, ALA4346I, ALA4354I, ALA4416I, ALA4421I, ALA4425I, ALA4426I, ALA4428I, ALA4429I, ALA4596I, ALA4600I, ALA4601I, ALA4615I, ALA4616I, ALA4638J, ALA4643J, ALA4685J, ALA4686J, ALA4812J, ALA4832J, ALA4859J, ALA4867J, ALA4905J, ALA4910J, ALA5056J, ALA5059J, ARG4112I, ARG4349I, ARG4523I, ARG4591I, ARG4609I, ARG4640J, ARG4862J, ARG4918J, ASN4122I, ASN4334I, ASN4422I, ASN4670J, ASN5058J, ASP4287I, ASP4289I, ASP4345I, ASP4352I, ASP4369I, ASP4434I, ASP4611I, ASP4612I, ASP4656J, ASP4661J, ASP4662J, ASP4665J, ASP4858J, ASP4865J, ASP4902J, ASP4903J, CYS4335I, GLN4119I, GLN4183I, GLN4223I, GLN4227I, GLN4230I, GLN4362I, GLN4385I, GLN4433I, GLN4595I, GLN4598I, GLN4833J, GLN4875J, GLN4906J, GLU4108I, GLU4169I, GLU4178I, GLU4186I, GLU4338I, GLU4341I, GLU4343I, GLU4347I, GLU4358I, GLU4361I, GLU4363I, GLU4364I, GLU4373I, GLU4413I, GLU4524I, GLU4602I, GLU4605I, GLU4617I, GLU4644J, GLU4678J, GLU4682J, GLU4775J, GLU4828J, GLU4851J, GLU4854J, GLU4860J, GLU4871J, GLU4874J, GLU4876J, GLU4877J, GLU4985J, GLU4989J, GLU4990J, GLU5057J, GLU5130J, GLY4115I, GLY4639J, GLY4654J, GLY4664J, GLY4771J, GLY4773J, GLY4811J, GLY4961J, GLY4982J, GLY5060J, HIS4170I, HIS4214I, HIS4683J, HIS4907J, HIS4986J, ILE4177I, ILE4217I, ILE4339I, ILE4348I, ILE4350I, ILE4360I, ILE4424I, ILE4427I, ILE4597I, ILE4610I, ILE4614I, ILE4641J, ILE4642J, ILE4675J, ILE4690J, ILE4814J, ILE4852J, ILE4861J, ILE4863J, ILE4873J, ILE4959J, LEU4106I, LEU4176I, LEU4290I, LEU4332I, LEU4356I, LEU4367I, LEU4430I, LEU4435I, LEU4607I, LEU4608I, LEU4637J, LEU4659J, LEU4663J, LEU4676J, LEU4869J, LEU4880J, LEU4904J, LEU5055J, LEU5061J, LYS4111I, LYS4174I, LYS4181I, LYS4185I, LYS4220I, LYS4285I, LYS4288I, LYS4340I, LYS4355I, LYS4365I, LYS4386I, LYS4409I, LYS4417I, LYS4461I, LYS4624J, LYS4653J, LYS4657J, LYS4687J, LYS4772J, LYS4776J, LYS4836J, LYS4853J, LYS4868J, LYS4911J, LYS4958J, MET4110I, MET4114I, MET4121I, MET4175I, MET4357I, MET4366I, MET4370I, MET4606I, MET4634J, MET4655J, MET4658J, MET4679J, MET4834J, MET4870J, MET4879J, PHE4359I, PHE4872J, PHE5087J, PRO4107I, PRO4171I, PRO4215I, PRO4652J, PRO4684J, PRO4866J, SER4431I, SER4599I, SER4603I, SER4648J, SER4680J, SER4810J, SER4813J, SER4831J, SER4960J, THR4182I, THR4216I, THR4342I, THR4344I, THR4351I, THR4594I, THR4645J, THR4649J, THR4669J, THR4855J, THR4864J, THR4983J, THR4984J, TYR4113I, TYR4908J, VAL4105I, VAL4168I, VAL4179I, VAL4218I, VAL4219I, VAL4286I, VAL4423I, VAL4613I, VAL4646J, VAL4660J, VAL4666J, VAL4667J, VAL4668J, VAL4681J, VAL4830J, VAL4987J, VAL5086J
• I-K: ALA4346I, ARG4349I, ARG5375K, ASP4345I, GLU4343I, GLU4347I, ILE5376K, ILE5386K, LEU5382K, MET5383K, THR4342I, THR4344I, THR5377K
• I-O: ARG4349I, ARG7427O
• I-P: ARG4349I, ARG7940P, ARG8200P, ASN8013P, ASP4143I, ASP4152I, ASP4345I, ASP4352I, ASP4389I, ASP7878P, ASP7880P, ASP7936P, ASP8025P, ASP8202P, ASP8203P, GLN4320I, GLU4169I, GLU4338I, GLU4341I, GLU4347I, GLU4363I, GLU4364I, GLU4472I, GLU4476I, GLU4477I, GLU7699P, GLU7769P, GLU7932P, GLU7934P, GLU7938P, GLU7949P, GLU8193P, HIS4394I, HIS4473I, HIS7805P, ILE4348I, ILE4350I, ILE8205P, LYS4140I, LYS4144I, LYS4263I, LYS4398I, LYS4445I, LYS7765P, LYS7772P, LYS7811P, LYS7876P, LYS7931P, LYS7946P, MET4145I, THR4351I, THR7935P, VAL4147I, VAL7696P
• J-K: ALA4631J, ALA4638J, ALA4685J, ALA4686J, ALA4693J, ALA4739J, ALA4859J, ALA4867J, ALA4929J, ALA4934J, ALA4938J, ALA4939J, ALA4941J, ALA4942J, ALA5109J, ALA5113J, ALA5114J, ALA5128J, ALA5129J, ALA5151K, ALA5156K, ALA5198K, ALA5199K, ALA5325K, ALA5345K, ALA5372K, ALA5380K, ALA5418K, ALA5423K, ALA5569K, ALA5572K, ARG4625J, ARG4862J, ARG5036J, ARG5104J, ARG5122J, ARG5153K, ARG5375K, ARG5431K, ASN4635J, ASN4847J, ASN4935J, ASN5183K, ASN5571K, ASP4800J, ASP4802J, ASP4858J, ASP4865J, ASP4882J, ASP4947J, ASP5124J, ASP5125J, ASP5169K, ASP5174K, ASP5175K, ASP5178K, ASP5371K, ASP5378K, ASP5415K, ASP5416K, CYS4848J, GLN4632J, GLN4696J, GLN4736J, GLN4740J, GLN4743J, GLN4875J, GLN4898J, GLN4946J, GLN5108J, GLN5111J, GLN5346K, GLN5388K, GLN5419K, GLU4621J, GLU4682J, GLU4691J, GLU4699J, GLU4851J, GLU4854J, GLU4856J, GLU4860J, GLU4871J, GLU4874J, GLU4876J, GLU4877J, GLU4886J, GLU4926J, GLU5037J, GLU5115J, GLU5118J, GLU5130J, GLU5157K, GLU5191K, GLU5195K, GLU5288K, GLU5341K, GLU5364K, GLU5367K, GLU5373K, GLU5384K, GLU5387K, GLU5389K, GLU5390K, GLU5498K, GLU5502K, GLU5503K, GLU5570K, GLU5643K, GLY4628J, GLY5152K, GLY5167K, GLY5177K, GLY5284K, GLY5286K, GLY5324K, GLY5474K, GLY5495K, GLY5573K, HIS4683J, HIS4727J, HIS5196K, HIS5420K, HIS5499K, ILE4690J, ILE4730J, ILE4852J, ILE4861J, ILE4863J, ILE4873J, ILE4937J, ILE4940J, ILE5110J, ILE5123J, ILE5127J, ILE5154K, ILE5155K, ILE5188K, ILE5203K, ILE5327K, ILE5365K, ILE5374K, ILE5376K, ILE5386K, ILE5472K, LEU4619J, LEU4689J, LEU4803J, LEU4845J, LEU4869J, LEU4880J, LEU4943J, LEU4948J, LEU5120J, LEU5121J, LEU5150K, LEU5172K, LEU5176K, LEU5189K, LEU5382K, LEU5393K, LEU5417K, LEU5568K, LEU5574K, LYS4624J, LYS4687J, LYS4694J, LYS4698J, LYS4733J, LYS4798J, LYS4801J, LYS4853J, LYS4868J, LYS4878J, LYS4899J, LYS4922J, LYS4930J, LYS4974J, LYS5137K, LYS5166K, LYS5170K, LYS5200K, LYS5285K, LYS5289K, LYS5349K, LYS5366K, LYS5381K, LYS5424K, LYS5471K, MET4623J, MET4627J, MET4634J, MET4688J, MET4870J, MET4879J, MET4883J, MET5119J, MET5147K, MET5168K, MET5171K, MET5192K, MET5347K, MET5383K, MET5392K, PHE4872J, PHE5385K, PHE5600K, PRO4620J, PRO4684J, PRO4728J, PRO5165K, PRO5197K, PRO5379K, SER4944J, SER5112J, SER5116J, SER5161K, SER5193K, SER5323K, SER5326K, SER5344K, SER5473K, THR4695J, THR4729J, THR4855J, THR4857J, THR4864J, THR5107J, THR5158K, THR5162K, THR5182K, THR5368K, THR5377K, THR5496K, THR5497K, TYR4626J, TYR5421K, VAL4618J, VAL4681J, VAL4692J, VAL4731J, VAL4732J, VAL4799J, VAL4936J, VAL5126J, VAL5159K, VAL5173K, VAL5179K, VAL5180K, VAL5181K, VAL5194K, VAL5343K, VAL5500K, VAL5599K
• J-L: ALA4859J, ARG4862J, ARG5888L, ASP4858J, GLU4856J, GLU4860J, ILE5889L, ILE5899L, LEU5895L, MET5896L, THR4855J, THR4857J, THR5890L
• J-P: ARG4862J, ARG7940P
• K-L: ALA5144K, ALA5151K, ALA5198K, ALA5199K, ALA5206K, ALA5252K, ALA5372K, ALA5380K, ALA5442K, ALA5447K, ALA5451K, ALA5452K, ALA5454K, ALA5455K, ALA5622K, ALA5626K, ALA5627K, ALA5641K, ALA5642K, ALA5664L, ALA5669L, ALA5711L, ALA5712L, ALA5838L, ALA5858L, ALA5885L, ALA5893L, ALA5931L, ALA5936L, ALA6082L, ALA6085L, ARG5138K, ARG5375K, ARG5549K, ARG5617K, ARG5635K, ARG5666L, ARG5888L, ARG5944L, ASN5148K, ASN5360K, ASN5448K, ASN5696L, ASN6084L, ASP5313K, ASP5315K, ASP5371K, ASP5378K, ASP5395K, ASP5460K, ASP5637K, ASP5638K, ASP5682L, ASP5687L, ASP5688L, ASP5691L, ASP5884L, ASP5891L, ASP5928L, ASP5929L, CYS5361K, GLN5145K, GLN5209K, GLN5249K, GLN5253K, GLN5256K, GLN5388K, GLN5411K, GLN5459K, GLN5621K, GLN5624K, GLN5859L, GLN5901L, GLN5932L, GLU5134K, GLU5195K, GLU5204K, GLU5212K, GLU5364K, GLU5367K, GLU5369K, GLU5373K, GLU5384K, GLU5387K, GLU5389K, GLU5390K, GLU5399K, GLU5439K, GLU5550K, GLU5628K, GLU5631K, GLU5643K, GLU5670L, GLU5704L, GLU5708L, GLU5801L, GLU5854L, GLU5877L, GLU5880L, GLU5886L, GLU5897L, GLU5900L, GLU5902L, GLU5903L, GLU6011L, GLU6015L, GLU6016L, GLU6083L, GLU6156L, GLY5141K, GLY5665L, GLY5680L, GLY5690L, GLY5797L, GLY5799L, GLY5837L, GLY5987L, GLY6008L, GLY6086L, HIS5196K, HIS5240K, HIS5709L, HIS5933L, HIS6012L, ILE5203K, ILE5243K, ILE5365K, ILE5374K, ILE5376K, ILE5386K, ILE5450K, ILE5453K, ILE5623K, ILE5636K, ILE5640K, ILE5667L, ILE5668L, ILE5701L, ILE5716L, ILE5840L, ILE5878L, ILE5887L, ILE5889L, ILE5899L, ILE5985L, LEU5132K, LEU5202K, LEU5316K, LEU5358K, LEU5382K, LEU5393K, LEU5456K, LEU5461K, LEU5633K, LEU5634K, LEU5663L, LEU5685L, LEU5689L, LEU5702L, LEU5895L, LEU5906L, LEU5930L, LEU6081L, LEU6087L, LYS5137K, LYS5200K, LYS5207K, LYS5211K, LYS5246K, LYS5311K, LYS5314K, LYS5366K, LYS5381K, LYS5391K, LYS5412K, LYS5435K, LYS5443K, LYS5487K, LYS5650L, LYS5679L, LYS5683L, LYS5713L, LYS5798L, LYS5802L, LYS5862L, LYS5879L, LYS5894L, LYS5937L, LYS5984L, MET5136K, MET5140K, MET5147K, MET5201K, MET5383K, MET5392K, MET5396K, MET5632K, MET5660L, MET5681L, MET5684L, MET5705L, MET5860L, MET5896L, MET5905L, PHE5385K, PHE5898L, PHE6113L, PRO5133K, PRO5197K, PRO5241K, PRO5678L, PRO5710L, PRO5892L, SER5457K, SER5625K, SER5629K, SER5674L, SER5706L, SER5836L, SER5839L, SER5857L, SER5986L, THR5208K, THR5242K, THR5368K, THR5370K, THR5377K, THR5620K, THR5671L, THR5675L, THR5695L, THR5881L, THR5890L, THR6009L, THR6010L, TYR5139K, TYR5934L, VAL5131K, VAL5194K, VAL5205K, VAL5244K, VAL5245K, VAL5312K, VAL5449K, VAL5639K, VAL5672L, VAL5686L, VAL5692L, VAL5693L, VAL5694L, VAL5707L, VAL5856L, VAL6013L, VAL6112L
• K-M: ALA5372K, ARG5375K, ARG6401M, ASP5371K, GLU5369K, GLU5373K, ILE6402M, ILE6412M, LEU6408M, MET6409M, THR5368K, THR5370K, THR6403M
• L-M: ALA5657L, ALA5664L, ALA5711L, ALA5712L, ALA5719L, ALA5765L, ALA5885L, ALA5893L, ALA5955L, ALA5960L, ALA5964L, ALA5965L, ALA5967L, ALA5968L, ALA6135L, ALA6139L, ALA6140L, ALA6154L, ALA6155L, ALA6177M, ALA6182M, ALA6224M, ALA6225M, ALA6351M, ALA6371M, ALA6398M, ALA6406M, ALA6444M, ALA6449M, ARG5651L, ARG5888L, ARG6130L, ARG6148L, ARG6179M, ARG6401M, ARG6457M, ASN5661L, ASN5873L, ASN5961L, ASN6209M, ASP5826L, ASP5828L, ASP5884L, ASP5891L, ASP5908L, ASP5973L, ASP6150L, ASP6151L, ASP6195M, ASP6200M, ASP6201M, ASP6204M, ASP6397M, ASP6404M, ASP6441M, ASP6442M, CYS5874L, GLN5658L, GLN5722L, GLN5762L, GLN5766L, GLN5769L, GLN5901L, GLN5924L, GLN5972L, GLN6134L, GLN6137L, GLN6372M, GLN6414M, GLN6445M, GLU5647L, GLU5708L, GLU5717L, GLU5725L, GLU5877L, GLU5880L, GLU5882L, GLU5886L, GLU5897L, GLU5900L, GLU5902L, GLU5903L, GLU5912L, GLU5952L, GLU6063L, GLU6141L, GLU6144L, GLU6156L, GLU6183M, GLU6217M, GLU6221M, GLU6314M, GLU6367M, GLU6390M, GLU6393M, GLU6399M, GLU6410M, GLU6413M, GLU6415M, GLU6416M, GLU6524M, GLU6528M, GLU6529M, GLY5654L, GLY6178M, GLY6193M, GLY6203M, GLY6310M, GLY6312M, GLY6350M, GLY6500M, GLY6521M, HIS5709L, HIS5753L, HIS6222M, HIS6446M, HIS6525M, ILE5716L, ILE5756L, ILE5878L, ILE5887L, ILE5889L, ILE5899L, ILE5963L, ILE5966L, ILE6136L, ILE6149L, ILE6153L, ILE6180M, ILE6181M, ILE6214M, ILE6229M, ILE6353M, ILE6391M, ILE6400M, ILE6402M, ILE6412M, ILE6498M, LEU5645L, LEU5715L, LEU5829L, LEU5871L, LEU5895L, LEU5906L, LEU5969L, LEU5974L, LEU6146L, LEU6147L, LEU6176M, LEU6198M, LEU6202M, LEU6215M, LEU6408M, LEU6419M, LEU6443M, LYS5650L, LYS5713L, LYS5720L, LYS5724L, LYS5759L, LYS5824L, LYS5827L, LYS5879L, LYS5894L, LYS5904L, LYS5925L, LYS5948L, LYS5956L, LYS6000L, LYS6163M, LYS6192M, LYS6196M, LYS6226M, LYS6311M, LYS6315M, LYS6375M, LYS6392M, LYS6407M, LYS6450M, LYS6497M, MET5649L, MET5653L, MET5660L, MET5714L, MET5896L, MET5905L, MET5909L, MET6145L, MET6173M, MET6194M, MET6197M, MET6218M, MET6373M, MET6409M, MET6418M, PHE5898L, PHE6411M, PRO5646L, PRO5710L, PRO5754L, PRO6191M, PRO6223M, PRO6405M, SER5970L, SER6138L, SER6142L, SER6187M, SER6219M, SER6349M, SER6352M, SER6370M, SER6499M, THR5721L, THR5755L, THR5881L, THR5883L, THR5890L, THR6133L, THR6184M, THR6188M, THR6208M, THR6394M, THR6403M, THR6522M, THR6523M, TYR5652L, TYR6447M, VAL5644L, VAL5707L, VAL5718L, VAL5757L, VAL5758L, VAL5825L, VAL5962L, VAL6152L, VAL6185M, VAL6199M, VAL6205M, VAL6206M, VAL6207M, VAL6220M, VAL6369M, VAL6526M
• L-N: ARG5888L, ARG6914N
• M-N: ARG6401M, ARG6661M, ARG6914N, ASN6474M, ASP6339M, ASP6341M, ASP6397M, ASP6486M, ASP6663M, ASP6664M, ASP6708N, ASP6717N, ASP6910N, ASP6917N, ASP6954N, GLN6885N, GLU6160M, GLU6230M, GLU6393M, GLU6395M, GLU6399M, GLU6410M, GLU6654M, GLU6734N, GLU6903N, GLU6906N, GLU6912N, GLU6928N, GLU6929N, GLU7037N, GLU7041N, GLU7042N, HIS6266M, HIS6959N, HIS7038N, ILE6666M, ILE6913N, ILE6915N, LYS6226M, LYS6233M, LYS6272M, LYS6337M, LYS6392M, LYS6407M, LYS6705N, LYS6709N, LYS6828N, LYS6963N, LYS7010N, MET6710N, THR6396M, THR6916N, VAL6157M, VAL6712N
• M-O: ARG6401M, ARG7427O
• N-O: ARG6914N, ARG7174N, ARG7427O, ASN6987N, ASP6852N, ASP6854N, ASP6910N, ASP6999N, ASP7176N, ASP7177N, ASP7221O, ASP7230O, ASP7423O, ASP7430O, ASP7467O, GLN7398O, GLU6673N, GLU6743N, GLU6906N, GLU6908N, GLU6912N, GLU6923N, GLU7167N, GLU7247O, GLU7416O, GLU7419O, GLU7425O, GLU7441O, GLU7442O, GLU7550O, GLU7554O, GLU7555O, HIS6779N, HIS7472O, HIS7551O, ILE7179N, ILE7426O, ILE7428O, LYS6739N, LYS6746N, LYS6785N, LYS6850N, LYS6905N, LYS6920N, LYS7218O, LYS7222O, LYS7341O, LYS7476O, LYS7523O, MET7223O, THR6909N, THR7429O, VAL6670N, VAL7225O
• N-P: ARG6914N, ARG7940P
• O-P: ARG7427O, ARG7687O, ARG7940P, ASN7500O, ASP7365O, ASP7367O, ASP7423O, ASP7512O, ASP7689O, ASP7690O, ASP7734P, ASP7743P, ASP7936P, ASP7943P, ASP7980P, GLN7911P, GLU7186O, GLU7256O, GLU7419O, GLU7421O, GLU7425O, GLU7436O, GLU7680O, GLU7760P, GLU7929P, GLU7932P, GLU7938P, GLU7954P, GLU7955P, GLU8063P, GLU8067P, GLU8068P, HIS7292O, HIS7985P, HIS8064P, ILE7692O, ILE7939P, ILE7941P, LYS7252O, LYS7259O, LYS7298O, LYS7363O, LYS7418O, LYS7433O, LYS7731P, LYS7735P, LYS7854P, LYS7989P, LYS8036P, MET7736P, THR7422O, THR7942P, VAL7183O, VAL7738P