3IYF

atomic model of the lidless mm-cpn in the open state

• Total interactions analyzed: 120
• Total true interactions: 32
• Strongest Interaction:
  • Chains: E-N
  • Int. Res.: 18
  • Norm. En. per Res.: -5.5851
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-42.8331	-3.8553	-48.4965	-95.1849	98	133	10	13073	1	26	31
A-H	-21.9692	7.0585	-170.589	-185.4997	95	123	10	12991	0	24	33
A-I	0.0	2.4783	-0.0633	2.4149	8	0	0	14	0	0	6
A-J	-3.3682	-85.2113	-31.8389	-120.4184	66	43	2	4987	1	33	33
B-C	-31.3412	28.0502	-188.611	-191.902	101	103	10	12990	1	25	32
B-J	0.0	3.5747	-0.0838	3.4909	8	0	0	22	0	0	6
B-K	-7.2228	-80.7683	-67.1589	-155.15	64	35	2	4789	1	36	34
C-D	-17.8243	10.5116	-215.209	-222.5218	92	90	10	12543	2	26	31
C-K	0.0	4.3239	-0.1367	4.1872	8	0	0	25	0	0	6
C-L	0.0	-103.8214	-78.6804	-182.5018	65	32	2	5070	3	35	32
D-E	-43.7932	18.3067	-211.556	-237.0425	99	120	9	13695	0	28	32
D-L	0.0	3.9069	-0.2175	3.6894	8	0	0	41	0	0	5
D-M	0.0	-88.7909	-60.6267	-149.4176	68	38	2	4947	2	36	32
E-F	-21.9528	-5.2868	-231.334	-258.5736	97	90	10	12798	2	25	31
E-M	0.0	3.8096	-0.0602	3.7493	8	0	0	28	0	0	6
E-N	-11.0675	-88.3565	-1.1078	-100.5318	18	0	0	216	0	2	2
F-G	-13.186	-6.5077	-198.926	-218.6198	101	117	9	13121	0	29	34
F-N	0.0	3.478	0.0	3.478	2	0	0	0	0	0	0
F-O	-9.4461	-85.4332			11
G-H	-41.5389	59.3874	-174.934	-157.0855	99	143	11	13930	0	26	31
G-O	0.0	1.1961			2
G-P	0.0	-77.1171			11
H-I	0.0	-88.8779	-82.8215	-171.6994	68	29	2	4977	2	32	30
H-P	0.0	1.2706			2
I-J	-18.0824	2.2946	-181.145	-196.9328	98	114	11	13419	0	25	35
I-P	-59.2599	-3.8648			22
J-K	-6.826	15.151	-209.854	-201.529	97	109	10	12775	0	26	31
K-L	-10.2963	1.2012	-207.14	-216.2351	96	103	10	12773	2	26	31
L-M	-20.2733	47.3416	-166.132	-139.0636	97	177	15	14554	1	28	31
M-N	-34.7605	31.9154	-33.3932	-36.2382	90	102	6	8048	0	18	17
N-O	-18.7909	-7.3175			19
O-P	-59.1437	53.8275			25

Interface residues

• A-B: ALA27B, ALA32B, ALA423B, ALA426B, ALA495A, ALA496A, ALA74A, ALA75A, ALA75B, ARG14A, ARG29B, ARG36B, ARG403A, ARG489A, ARG66B, ASN114A, ASN11A, ASN24A, ASN425B, ASN59B, ASP429B, ASP45B, ASP491A, ASP492A, ASP50B, ASP51B, ASP54B, GLU10A, GLU33B, GLU424B, GLU497A, GLU67B, GLU71A, GLU71B, GLY28B, GLY427B, GLY43B, GLY53B, GLY61B, HIS116A, HIS72A, HIS72B, ILE119A, ILE30B, ILE31B, ILE490A, ILE494A, ILE64B, ILE79B, LEU111A, LEU422B, LEU428B, LEU488A, LEU48B, LEU52B, LEU65B, LEU78B, LEU8A, LYS122A, LYS13A, LYS42B, LYS46B, LYS76A, LYS76B, MET12A, MET16A, MET23A, MET44B, MET47B, MET486A, MET68B, MET77A, PHE454B, PRO117A, PRO41B, PRO73A, PRO9A, SER37B, SER69B, THR118A, THR34B, THR38B, THR421B, THR58B, THR63B, TYR15A, VAL115A, VAL121A, VAL35B, VAL453B, VAL493A, VAL49B, VAL55B, VAL56B, VAL57B, VAL62B, VAL70B, VAL7A
• A-H: ALA20H, ALA27A, ALA32A, ALA423A, ALA426A, ALA495H, ALA496H, ALA74H, ALA75A, ALA75H, ARG14H, ARG29A, ARG36A, ARG403H, ARG489H, ARG66A, ASN114H, ASN11H, ASN24H, ASN425A, ASN59A, ASP45A, ASP491H, ASP492H, ASP50A, ASP51A, ASP54A, GLU10H, GLU33A, GLU424A, GLU497H, GLU67A, GLU71A, GLU71H, GLY162A, GLY17H, GLY40A, GLY427A, GLY43A, GLY53A, HIS116H, HIS72A, HIS72H, ILE119H, ILE30A, ILE31A, ILE490H, ILE494H, ILE64A, ILE79A, LEU428A, LEU487H, LEU488H, LEU48A, LEU52A, LEU65A, LEU8H, LYS122H, LYS13H, LYS42A, LYS46A, LYS76A, LYS76H, MET12H, MET16H, MET23H, MET44A, MET47A, MET486H, MET68A, MET77H, PHE454A, PRO117H, PRO41A, PRO73A, PRO73H, PRO9H, SER37A, SER69A, THR118H, THR34A, THR38A, THR58A, TYR15H, VAL115H, VAL121H, VAL35A, VAL453A, VAL493H, VAL49A, VAL55A, VAL56A, VAL57A, VAL70A, VAL7H
• A-I: ASP429A, ASP429I, GLU432A, GLU432I, GLY427A, GLY427I, LEU428A, LEU428I
• A-J: ALA397A, ALA397J, ALA407A, ALA407J, ALA430A, ALA430J, ALA439A, ALA439J, ARG394A, ARG394J, ARG403A, ARG403J, ARG409A, ARG409J, ARG420A, ARG420J, ARG438A, ARG438J, ASP413A, ASP413J, ASP429A, ASP429J, GLN113A, GLN113J, GLN405A, GLN405J, GLU395A, GLU395J, GLU398A, GLU398J, GLU404A, GLU404J, GLU416A, GLU416J, GLU424A, GLU424J, GLU432A, GLU432J, GLY399A, GLY399J, GLY402A, GLY402J, ILE119A, ILE119J, ILE400A, ILE400J, ILE431A, ILE431J, LEU110A, LEU110J, LEU406A, LEU406J, LEU434A, LEU434J, LYS436A, LYS436J, MET391A, MET391J, SER390A, SER390J, SER401A, SER401J, VAL115A, VAL115J, VAL435A, VAL435J
• B-C: ALA27C, ALA32C, ALA423C, ALA426C, ALA495B, ALA496B, ALA74B, ALA74C, ALA75B, ALA75C, ARG14B, ARG36C, ARG403B, ARG489B, ARG66C, ASN114B, ASN11B, ASN24B, ASN425C, ASN59C, ASP429C, ASP45C, ASP491B, ASP492B, ASP50C, ASP51C, ASP54C, GLU10B, GLU33C, GLU424C, GLU497B, GLU67C, GLU71B, GLU71C, GLU80B, GLY160C, GLY162C, GLY28C, GLY427C, GLY43C, GLY53C, HIS116B, HIS72B, HIS72C, ILE119B, ILE30C, ILE31C, ILE490B, ILE494B, ILE64C, ILE79C, LEU26C, LEU422C, LEU428C, LEU487B, LEU488B, LEU48C, LEU52C, LEU65C, LEU78C, LEU8B, LYS122B, LYS13B, LYS165C, LYS42C, LYS46C, LYS76B, LYS76C, MET12B, MET16B, MET23B, MET44C, MET47C, MET486B, MET68C, MET77B, MET77C, PHE454C, PRO117B, PRO41C, PRO73B, PRO73C, PRO9B, SER37C, SER69C, THR118B, THR34C, THR38C, THR58C, TYR15B, VAL115B, VAL121B, VAL35C, VAL453C, VAL493B, VAL49C, VAL55C, VAL56C, VAL57C, VAL70C, VAL7B
• B-J: ASP429B, ASP429J, GLU432B, GLU432J, GLY427B, GLY427J, LEU428B, LEU428J
• B-K: ALA397B, ALA397K, ALA407B, ALA407K, ALA430B, ALA430K, ALA439B, ALA439K, ARG394B, ARG394K, ARG403B, ARG403K, ARG409B, ARG409K, ARG420B, ARG420K, ARG438B, ARG438K, ASP413B, ASP413K, ASP429B, ASP429K, GLN113B, GLN113K, GLN405B, GLN405K, GLU395B, GLU395K, GLU398B, GLU398K, GLU404B, GLU404K, GLU416B, GLU416K, GLU424B, GLU432B, GLU432K, GLY399B, GLY399K, GLY402B, GLY402K, ILE119B, ILE119K, ILE400B, ILE400K, ILE431B, ILE431K, LEU110B, LEU110K, LEU406B, LEU406K, LEU434B, LEU434K, LYS436B, LYS436K, MET391B, MET391K, SER390K, SER401B, SER401K, VAL115B, VAL115K, VAL435B, VAL435K
• C-D: ALA27D, ALA32D, ALA423D, ALA426D, ALA495C, ALA496C, ALA74C, ALA75C, ALA75D, ARG14C, ARG36D, ARG403C, ARG489C, ARG66D, ASN114C, ASN11C, ASN24C, ASN425D, ASN59D, ASP45D, ASP491C, ASP492C, ASP50D, ASP51D, ASP54D, GLN21C, GLU10C, GLU33D, GLU424D, GLU497C, GLU67D, GLU71D, GLU80C, GLY160D, GLY17C, GLY427D, GLY43D, GLY53D, HIS116C, HIS72C, HIS72D, ILE119C, ILE30D, ILE31D, ILE490C, ILE494C, ILE64D, ILE79D, LEU428D, LEU488C, LEU48D, LEU52D, LEU65D, LEU78D, LEU8C, LYS122C, LYS13C, LYS42D, LYS46D, LYS76C, LYS76D, MET12C, MET16C, MET44D, MET47D, MET486C, MET68D, MET77C, PHE454D, PRO117C, PRO41D, PRO73C, PRO9C, SER37D, SER69D, THR118C, THR34D, THR38D, THR58D, TYR15C, VAL115C, VAL120C, VAL121C, VAL35D, VAL453D, VAL493C, VAL49D, VAL55D, VAL56D, VAL57D, VAL70D, VAL7C
• C-K: ASP429C, ASP429K, GLU432C, GLU432K, GLY427C, GLY427K, LEU428C, LEU428K
• C-L: ALA397C, ALA397L, ALA407C, ALA407L, ALA430C, ALA430L, ALA439C, ALA439L, ALA442C, ARG394C, ARG394L, ARG403C, ARG403L, ARG409C, ARG409L, ARG420C, ARG420L, ARG438C, ARG438L, ASP413C, ASP413L, ASP429C, ASP429L, GLN113C, GLN113L, GLN405C, GLN405L, GLU395C, GLU395L, GLU398C, GLU398L, GLU404C, GLU404L, GLU416C, GLU416L, GLU424C, GLU432C, GLU432L, GLY399C, GLY399L, GLY402C, GLY402L, ILE119C, ILE119L, ILE400C, ILE400L, ILE431C, ILE431L, ILE433L, LEU110C, LEU110L, LEU406C, LEU406L, LEU434C, LEU434L, LYS436C, LYS436L, MET391C, MET391L, SER401C, SER401L, VAL115C, VAL115L, VAL435C, VAL435L
• D-E: ALA27D, ALA27E, ALA32E, ALA423E, ALA426E, ALA495D, ALA496D, ALA74D, ALA74E, ALA75D, ALA75E, ARG14D, ARG29E, ARG36E, ARG403D, ARG489D, ARG66E, ASN114D, ASN11D, ASN24D, ASN425E, ASN59E, ASP429E, ASP45E, ASP491D, ASP492D, ASP50E, ASP51E, ASP54E, GLU10D, GLU33E, GLU424E, GLU497D, GLU67E, GLU71D, GLU71E, GLY40E, GLY427E, GLY43E, GLY53E, GLY61E, HIS116D, HIS72D, HIS72E, ILE119D, ILE30E, ILE31E, ILE490D, ILE494D, ILE64E, ILE79E, LEU428E, LEU487D, LEU488D, LEU48E, LEU52E, LEU65E, LEU78E, LEU8D, LYS122D, LYS13D, LYS42E, LYS46E, LYS76D, LYS76E, MET12D, MET16D, MET23D, MET44E, MET47E, MET486D, MET68E, MET77D, MET77E, PHE454E, PRO117D, PRO41E, PRO73D, PRO9D, SER37E, SER69E, THR118D, THR34E, THR38E, THR58E, THR63E, TYR15D, VAL115D, VAL121D, VAL35E, VAL453E, VAL493D, VAL49E, VAL55E, VAL56E, VAL57E, VAL62E, VAL70E, VAL7D
• D-L: ASP429D, ASP429L, GLU432D, GLU432L, GLY427D, GLY427L, LEU428D, LEU428L
• D-M: ALA397D, ALA397M, ALA407D, ALA407M, ALA430D, ALA430M, ALA439D, ALA439M, ARG394D, ARG394M, ARG403D, ARG403M, ARG409D, ARG409M, ARG420D, ARG420M, ARG438D, ARG438M, ASN114D, ASP413D, ASP413M, ASP429D, ASP429M, GLN113D, GLN113M, GLN405D, GLN405M, GLU395D, GLU395M, GLU398D, GLU398M, GLU404D, GLU404M, GLU416D, GLU416M, GLU424M, GLU432D, GLU432M, GLY399D, GLY399M, GLY402D, GLY402M, ILE119D, ILE119M, ILE400D, ILE400M, ILE431D, ILE431M, ILE433D, ILE433M, LEU110D, LEU110M, LEU406D, LEU406M, LEU434D, LEU434M, LYS436D, LYS436M, MET391D, MET391M, SER390D, SER390M, SER401D, SER401M, VAL115D, VAL115M, VAL435D, VAL435M
• E-F: ALA20E, ALA27F, ALA32F, ALA423F, ALA426F, ALA495E, ALA496E, ALA74E, ALA74F, ALA75E, ALA75F, ARG14E, ARG36F, ARG403E, ARG489E, ARG66F, ASN114E, ASN11E, ASN24E, ASN425F, ASN59F, ASP429F, ASP45F, ASP491E, ASP492E, ASP50F, ASP51F, ASP54F, GLU10E, GLU33F, GLU424F, GLU497E, GLU67F, GLU71E, GLU71F, GLY160F, GLY17E, GLY427F, GLY43F, GLY53F, HIS116E, HIS72E, HIS72F, ILE119E, ILE30F, ILE31F, ILE490E, ILE494E, ILE64F, ILE79F, LEU422F, LEU428F, LEU487E, LEU488E, LEU48F, LEU52F, LEU65F, LEU78F, LEU8E, LYS122E, LYS13E, LYS42F, LYS46F, LYS76E, LYS76F, MET12E, MET16E, MET23E, MET44F, MET47F, MET486E, MET68F, MET77E, PHE454F, PRO117E, PRO41F, PRO73E, PRO9E, SER37F, SER69F, THR118E, THR34F, THR38F, THR455F, THR58F, TYR15E, VAL115E, VAL121E, VAL35F, VAL453F, VAL493E, VAL49F, VAL55F, VAL56F, VAL57F, VAL70F, VAL7E
• E-M: ASP429E, ASP429M, GLU432E, GLU432M, GLY427E, GLY427M, LEU428E, LEU428M
• E-N: ARG394N, ARG403E, ARG403N, ARG420E, ARG438E, ARG438N, ASP429E, ASP429N, GLN113N, GLU398E, GLU398N, GLU424E, GLU432E, GLU432N, ILE119N, ILE431E, LEU110N, VAL115N
• F-G: ALA27G, ALA32G, ALA423G, ALA426G, ALA495F, ALA496F, ALA74F, ALA74G, ALA75F, ALA75G, ARG14F, ARG29G, ARG36G, ARG403F, ARG489F, ARG66G, ASN114F, ASN11F, ASN24F, ASN425G, ASN59G, ASP429G, ASP45G, ASP491F, ASP492F, ASP50G, ASP51G, ASP54G, GLU10F, GLU33G, GLU424G, GLU497F, GLU67G, GLU71F, GLU71G, GLY162G, GLY17F, GLY28G, GLY40G, GLY427G, GLY43G, GLY53G, HIS116F, HIS72F, HIS72G, ILE119F, ILE30G, ILE31G, ILE490F, ILE494F, ILE64G, ILE79G, LEU428G, LEU488F, LEU48G, LEU52G, LEU65G, LEU78G, LEU8F, LYS122F, LYS13F, LYS187F, LYS325G, LYS42G, LYS46G, LYS76F, LYS76G, MET12F, MET16F, MET23F, MET44G, MET47G, MET486F, MET68G, MET77F, MET77G, PHE454G, PRO117F, PRO41G, PRO73F, PRO73G, PRO9F, SER37G, SER69G, THR118F, THR34G, THR38G, THR455G, THR58G, TYR15F, VAL115F, VAL121F, VAL35G, VAL453G, VAL493F, VAL49G, VAL55G, VAL56G, VAL57G, VAL70G, VAL7F
• F-N: ASP429F, ASP429N
• F-O: ARG403F, ARG403O, ARG438F, ARG438O, ASP429F, ASP429O, GLN405O, GLU398F, GLU398O, GLU432F, GLU432O
• G-H: ALA20G, ALA27H, ALA32H, ALA423H, ALA426H, ALA495G, ALA496G, ALA74G, ALA74H, ALA75G, ALA75H, ARG14G, ARG36H, ARG403G, ARG489G, ARG66H, ASN114G, ASN11G, ASN24G, ASN425H, ASN59H, ASP429H, ASP45H, ASP491G, ASP492G, ASP50H, ASP51H, ASP54H, GLU10G, GLU33H, GLU424H, GLU497G, GLU67H, GLU71H, GLU80G, GLY162H, GLY17G, GLY28H, GLY40H, GLY427H, GLY43H, GLY53H, HIS116G, HIS72G, HIS72H, ILE119G, ILE30H, ILE31H, ILE490G, ILE494G, ILE64H, ILE79H, LEU26H, LEU428H, LEU487G, LEU488G, LEU48H, LEU52H, LEU65H, LEU78H, LEU8G, LYS122G, LYS13G, LYS42H, LYS46H, LYS76G, LYS76H, MET12G, MET16G, MET23H, MET44H, MET47H, MET486G, MET68H, MET77G, PHE454H, PRO117G, PRO41H, PRO73G, PRO73H, PRO9G, SER37H, SER69H, THR118G, THR34H, THR38H, THR58H, TYR15G, VAL115G, VAL121G, VAL35H, VAL453H, VAL493G, VAL49H, VAL55H, VAL56H, VAL57H, VAL70H, VAL7G
• G-O: ASP429G, ASP429O
• G-P: ARG394P, ARG403G, ARG403P, ARG438G, ARG438P, ASP429G, ASP429P, GLU398G, GLU398P, GLU432G, GLU432P
• H-I: ALA397H, ALA397I, ALA407H, ALA407I, ALA430H, ALA430I, ALA439H, ALA439I, ARG105H, ARG394H, ARG394I, ARG403H, ARG403I, ARG409H, ARG409I, ARG420H, ARG420I, ARG438H, ARG438I, ASN114I, ASP413H, ASP413I, ASP429H, ASP429I, GLN113H, GLN113I, GLN405H, GLN405I, GLU395H, GLU395I, GLU398H, GLU398I, GLU404H, GLU404I, GLU416H, GLU416I, GLU424H, GLU424I, GLU432H, GLU432I, GLY399H, GLY399I, GLY402H, GLY402I, ILE119H, ILE119I, ILE400H, ILE400I, ILE431H, ILE431I, ILE433H, LEU110H, LEU110I, LEU406H, LEU406I, LEU434H, LEU434I, LYS436H, LYS436I, MET391H, MET391I, SER390I, SER401H, SER401I, VAL115H, VAL115I, VAL435H, VAL435I
• H-P: ASP429H, ASP429P
• I-J: ALA27I, ALA32I, ALA423I, ALA426I, ALA495J, ALA496J, ALA74I, ALA74J, ALA75I, ALA75J, ARG14J, ARG36I, ARG403J, ARG489J, ARG66I, ASN114J, ASN11J, ASN24J, ASN425I, ASN59I, ASP429I, ASP45I, ASP491J, ASP492J, ASP50I, ASP51I, ASP54I, GLU10J, GLU33I, GLU424I, GLU497I, GLU497J, GLU67I, GLU71I, GLU71J, GLY28I, GLY40I, GLY427I, GLY43I, GLY53I, HIS116J, HIS72I, HIS72J, ILE119J, ILE30I, ILE31I, ILE490J, ILE494J, ILE64I, ILE79I, LEU428I, LEU487J, LEU488J, LEU48I, LEU52I, LEU65I, LEU78I, LEU8J, LYS122J, LYS13J, LYS42I, LYS46I, LYS76I, LYS76J, MET12J, MET16J, MET23J, MET44I, MET47I, MET486J, MET68I, MET77I, MET77J, PHE454I, PRO117J, PRO41I, PRO73I, PRO73J, PRO9J, SER37I, SER69I, THR118J, THR34I, THR38I, THR455I, THR58I, TYR15J, VAL115J, VAL121J, VAL35I, VAL453I, VAL493J, VAL49I, VAL55I, VAL56I, VAL57I, VAL70I, VAL7J
• I-P: ALA426P, ARG14I, ARG489I, ASP45P, ASP491I, ASP492I, ASP50P, ASP51P, GLU10I, GLU424P, GLU71P, GLY43P, HIS116I, ILE494I, LEU8I, LYS42P, LYS46P, MET47P, MET68P, THR118I, THR34P, VAL7I
• J-K: ALA27J, ALA32J, ALA423J, ALA426J, ALA495K, ALA496K, ALA74J, ALA74K, ALA75J, ALA75K, ARG14K, ARG29J, ARG36J, ARG403K, ARG489K, ARG66J, ASN114K, ASN11K, ASN24K, ASN425J, ASN59J, ASP429J, ASP45J, ASP491K, ASP492K, ASP50J, ASP51J, ASP54J, GLU10K, GLU33J, GLU424J, GLU497K, GLU67J, GLU71J, GLU71K, GLY17K, GLY28J, GLY40J, GLY427J, GLY43J, GLY53J, HIS116K, HIS72J, HIS72K, ILE119K, ILE30J, ILE31J, ILE490K, ILE494K, ILE64J, ILE79J, LEU26J, LEU428J, LEU488K, LEU48J, LEU52J, LEU65J, LEU78J, LEU8K, LYS122K, LYS13K, LYS42J, LYS46J, LYS76J, LYS76K, MET12K, MET16K, MET23K, MET44J, MET47J, MET486K, MET68J, MET77K, PHE454J, PRO117K, PRO41J, PRO73J, PRO73K, PRO9K, SER37J, SER69J, THR118K, THR34J, THR38J, THR58J, TYR15K, VAL115K, VAL121K, VAL35J, VAL453J, VAL493K, VAL49J, VAL55J, VAL56J, VAL57J, VAL70J, VAL7K
• K-L: ALA27K, ALA32K, ALA423K, ALA426K, ALA495L, ALA496L, ALA74L, ALA75K, ALA75L, ARG14L, ARG29K, ARG36K, ARG403L, ARG489L, ARG66K, ASN114L, ASN11L, ASN24L, ASN425K, ASN59K, ASP429K, ASP45K, ASP491L, ASP492L, ASP50K, ASP51K, ASP54K, GLU10L, GLU33K, GLU424K, GLU497L, GLU67K, GLU71K, GLU71L, GLY427K, GLY43K, GLY53K, GLY61K, HIS116L, HIS72K, HIS72L, ILE119L, ILE30K, ILE31K, ILE490L, ILE494L, ILE64K, ILE79K, LEU428K, LEU487L, LEU488L, LEU48K, LEU52K, LEU65K, LEU78K, LEU8L, LYS122L, LYS13L, LYS42K, LYS46K, LYS76K, LYS76L, MET12L, MET16L, MET23L, MET44K, MET47K, MET486L, MET68K, MET77L, PHE454K, PRO117L, PRO41K, PRO73K, PRO73L, PRO9L, SER37K, SER69K, THR118L, THR34K, THR38K, THR58K, THR63K, TYR15L, VAL115L, VAL121L, VAL35K, VAL453K, VAL493L, VAL49K, VAL55K, VAL56K, VAL57K, VAL62K, VAL70K, VAL7L
• L-M: ALA27L, ALA32L, ALA423L, ALA426L, ALA495M, ALA496M, ALA74L, ALA74M, ALA75L, ALA75M, ARG14M, ARG36L, ARG403M, ARG489M, ARG66L, ASN114M, ASN11M, ASN24M, ASN425L, ASN59L, ASP45L, ASP491M, ASP492M, ASP50L, ASP51L, ASP54L, GLU10M, GLU33L, GLU424L, GLU497M, GLU67L, GLU71L, GLU71M, GLU80L, GLU80M, GLY17M, GLY28L, GLY427L, GLY43L, GLY53L, HIS116M, HIS72L, HIS72M, ILE119M, ILE30L, ILE31L, ILE490M, ILE494M, ILE64L, ILE79L, LEU422L, LEU428L, LEU488M, LEU48L, LEU52L, LEU65L, LEU78L, LEU8M, LYS122M, LYS13M, LYS42L, LYS46L, LYS76L, LYS76M, MET12M, MET16M, MET23M, MET44L, MET47L, MET486M, MET68L, MET77L, MET77M, PHE454L, PRO117M, PRO41L, PRO73L, PRO73M, PRO9M, SER37L, SER69L, THR118M, THR34L, THR38L, THR58L, TYR15M, VAL115M, VAL121M, VAL35L, VAL453L, VAL493M, VAL49L, VAL55L, VAL56L, VAL57L, VAL70L, VAL7M
• M-N: ALA27M, ALA32M, ALA423M, ALA426M, ALA74N, ALA75M, ALA75N, ARG14N, ARG29M, ARG36M, ARG489N, ARG66M, ASN114N, ASN11N, ASN24N, ASN425M, ASP45M, ASP491N, ASP492N, ASP50M, ASP51M, ASP54M, GLU10N, GLU33M, GLU424M, GLU497N, GLU67M, GLU71M, GLU71N, GLU80M, GLY17N, GLY28M, GLY427M, GLY43M, GLY53M, GLY61M, HIS116N, HIS72M, HIS72N, ILE119N, ILE30M, ILE31M, ILE494N, ILE64M, ILE79M, LEU422M, LEU428M, LEU48M, LEU52M, LEU65M, LEU78M, LEU8N, LYS122N, LYS13N, LYS42M, LYS46M, LYS76M, LYS76N, MET12N, MET16N, MET23N, MET44M, MET47M, MET68M, MET77M, MET77N, PHE454M, PRO117N, PRO41M, PRO73M, PRO73N, PRO9N, SER37M, SER69M, THR118N, THR34M, THR38M, TYR15N, VAL115N, VAL120N, VAL121N, VAL35M, VAL453M, VAL49M, VAL55M, VAL56M, VAL57M, VAL70M, VAL7N, VAL97M
• N-O: ARG14O, ARG489O, ASP45N, ASP491O, ASP492O, ASP50N, ASP51N, GLU10O, GLU33N, GLU424N, GLU497O, GLU71N, HIS116O, ILE494O, LYS42N, LYS46N, MET47N, VAL70N, VAL7O
• O-P: ARG14P, ARG489P, ASN11P, ASP45O, ASP491P, ASP492P, ASP50O, ASP51O, ASP54O, GLU10P, GLU33O, GLU424O, GLU497P, GLU67O, GLU71O, HIS116P, ILE494P, LEU52O, LEU8P, LYS42O, LYS46O, MET47O, VAL49O, VAL70O, VAL7P