3IXW

scorpion hemocyanin activated state pseudo atomic model built based on cryo-em density map

• Total interactions analyzed: 66
• Total true interactions: 27
• Strongest Interaction:
  • Chains: J-L
  • Int. Res.: 19
  • Norm. En. per Res.: -5.8744
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-46.0568	-63.1057	-117.633	-226.7954	129	14	3	7466	6	36	40
A-D	0.0	1.2926	-45.2743	-43.9817	42	5	4	2401	0	6	14
A-E	-15.2386	-53.3588	-110.245	-178.8423	71	7	0	4323	4	50	46
A-G	-4.5765	-52.6784	-75.3311	-132.5861	56	9	0	3091	3	44	37
C-D	0.0	-52.9543	-70.4239	-123.3782	60	13	0	3189	2	45	38
C-F	-23.8479	-56.5997	-86.1845	-166.632	64	20	0	3920	2	49	41
C-G	0.0	0.678	0.9591	1.637	38	23	3	2120	0	5	13
C-I	-8.981	38.6531	-98.5797	-68.9076	94	13	0	4618	0	76	83
D-E	-19.8482	-54.4514	-166.81	-241.1096	149	21	4	9628	4	39	47
D-F	-13.4329	-65.3218	-82.4337	-161.1884	69	18	0	3865	2	52	46
D-I	0.0	0.0	-0.0025	-0.0025	2	0	0	1	0	1	0
E-F	0.0	2.2209	-69.1562	-66.9353	46	5	4	3143	0	6	18
E-G	-26.5959	-50.7925	-100.832	-178.2204	72	18	0	4156	3	49	47
F-G	-46.7203	-66.3709	-178.214	-291.3053	153	20	4	10408	4	47	48
F-I	0.0	0.0	-8.0336	-8.0336	16	0	0	651	0	5	6
H-I	-32.3579	-50.2312	-134.699	-217.2882	137	15	4	8661	5	38	45
H-J	0.0	0.6469	65.8106	66.4574	42	36	4	2406	0	5	15
H-K	0.0	-53.3169	-75.5402	-128.8571	69	21	0	3895	2	49	45
H-M	0.0	-54.6722			12
I-J	-13.1506	-62.5624	-75.5487	-151.2617	60	14	0	3386	4	47	42
I-L	-3.7086	-56.2962	-9.2863	-69.291	24	1	0	373	0	3	3
I-M	0.0	1.3103			4
J-K	-54.4696	-49.1687	-263.662	-367.3004	162	34	4	13427	4	51	55
J-L	-34.3308	-77.2832	0.0	-111.614	19	0	0	0	0	0	0
K-L	0.0	1.7937	0.0	1.7937	4	0	0	0	0	0	0
K-M	-23.7138	-45.3697			14
L-M	-49.5864	-46.6277			23

Interface residues

• A-C: ALA121A, ALA121C, ALA127A, ALA18A, ALA18C, ALA234A, ALA234C, ALA247A, ALA247C, ARG126A, ARG126C, ARG21A, ARG21C, ARG249A, ARG249C, ARG337A, ARG337C, ARG41A, ARG41C, ARG51C, ASN125A, ASN125C, ASN128C, ASN133A, ASN133C, ASN149A, ASN149C, ASN341A, ASN341C, ASN419A, ASN419C, ASP152A, ASP152C, ASP333A, ASP333C, ASP335A, ASP335C, GLN245A, GLN245C, GLN339A, GLN339C, GLU122A, GLU122C, GLU130A, GLU130C, GLU146A, GLU146C, GLU231A, GLU231C, GLU251A, GLU251C, GLU340A, GLU340C, GLY148A, GLY148C, GLY232A, GLY232C, GLY243A, GLY243C, GLY252A, GLY252C, GLY421A, GLY421C, GLY42C, HIS134A, HIS134C, HIS15C, HIS236A, HIS236C, HIS256A, HIS256C, HIS336A, HIS336C, ILE124A, ILE124C, ILE150A, ILE150C, ILE331A, ILE331C, ILE418C, LEU151A, LEU151C, LEU230C, LEU237A, LEU240A, LEU240C, LEU244A, LEU244C, LEU44A, LEU44C, LYS129A, LYS129C, PHE338A, PHE338C, PRO135A, PRO135C, PRO235A, PRO250A, PRO250C, PRO334A, PRO334C, PRO355A, PRO40C, SER132A, SER132C, SER239A, SER239C, SER242A, SER242C, SER248A, SER248C, SER254C, THR147A, THR147C, THR17A, THR17C, THR238A, THR238C, THR332A, THR332C, THR43A, THR43C, TYR233A, TYR233C, TYR253A, TYR253C, VAL142A, VAL241A, VAL241C
• A-D: ARG219A, ARG219D, ASN149A, ASN149D, ASN468A, ASN468D, ASN469A, ASN469D, ASP152A, ASP152D, ASP465A, ASP465D, GLN218A, GLN218D, GLU466A, GLU466D, GLU472A, GLU472D, GLU475A, GLU475D, GLY148A, GLY148D, HIS546A, HIS546D, ILE150A, ILE150D, LEU151A, LEU151D, LEU467A, LEU467D, LYS156A, LYS156D, LYS470A, LYS470D, LYS547A, LYS547D, PRO153A, PRO153D, THR147A, THR147D, TYR155A, TYR155D
• A-E: ALA276A, ALA54E, ALA604A, ARG268A, ARG268E, ARG270A, ARG272A, ARG272E, ARG51E, ARG605A, ASN225A, ASN278A, ASN287E, ASN313E, ASP227A, ASP257E, ASP260E, ASP262E, ASP265E, ASP275A, ASP284E, ASP286E, ASP474A, GLN264E, GLU271A, GLU271E, GLU315E, GLU370A, GLU472A, GLU475A, GLU55E, GLU603A, GLU609A, GLY318E, GLY35E, GLY37E, HIS224A, HIS280A, HIS376A, HIS52E, ILE273A, ILE277A, ILE367A, ILE38E, LEU274A, LEU292A, LEU39E, LYS285E, LYS289A, LYS289E, LYS34E, LYS373A, LYS601A, MET279A, PHE226A, PHE363A, PRO291A, SER374A, TRP269A, TRP269E, TYR281A, TYR281E, TYR316E, TYR317E, VAL261E, VAL263E, VAL267A, VAL267E, VAL283E, VAL314E, VAL36E
• A-G: ALA276G, ARG268A, ARG268G, ARG270G, ARG272A, ARG272G, ARG337A, ARG51A, ARG605G, ASN225G, ASN278G, ASN287A, ASN313A, ASP227G, ASP257A, ASP262A, ASP265A, ASP275G, GLN264A, GLU228G, GLU271A, GLU271G, GLU315A, GLU370G, GLU472G, GLU475G, GLU55A, GLY35A, GLY37A, HIS224G, HIS280G, HIS52A, ILE273G, ILE277G, ILE38A, LEU274G, LEU39A, LEU467G, LYS285A, LYS289A, LYS289G, MET279G, PHE226G, PHE363G, PRO40A, SER374G, TRP269A, TRP269G, TYR281G, TYR316A, VAL261A, VAL263A, VAL267A, VAL267G, VAL283A, VAL36A
• C-D: ALA276D, ALA54C, ALA604D, ARG268C, ARG268D, ARG270D, ARG272C, ARG272D, ARG51C, ARG605D, ASN225D, ASN278D, ASN287C, ASN313C, ASP257C, ASP262C, ASP265C, ASP275D, ASP284C, ASP286C, ASP474D, GLN264C, GLU271D, GLU315C, GLU370D, GLU472D, GLU475D, GLU55C, GLU603D, GLU609D, GLY35C, GLY37C, HIS224D, HIS280D, HIS52C, ILE273D, ILE277D, ILE38C, LEU274D, LEU39C, LYS285C, LYS289C, LYS289D, LYS34C, LYS601D, MET279D, PHE226D, PHE363D, SER374D, TRP269C, TRP269D, TYR281D, TYR316C, VAL261C, VAL263C, VAL267C, VAL267D, VAL283C, VAL314C, VAL36C
• C-F: ALA276C, ALA54F, ALA604C, ARG268C, ARG268F, ARG270C, ARG272C, ARG272F, ARG51F, ARG605C, ASN225C, ASN278C, ASN287F, ASN313F, ASP257F, ASP260F, ASP262F, ASP265F, ASP275C, ASP474C, GLN264F, GLU271C, GLU271F, GLU315F, GLU370C, GLU472C, GLU475C, GLU55F, GLU603C, GLY318F, GLY35F, GLY37F, HIS224C, HIS280C, HIS376C, HIS52F, ILE273C, ILE277C, ILE38F, LEU274C, LEU39F, LYS285F, LYS289C, LYS289F, LYS34F, LYS373C, LYS601C, MET266F, MET279C, PHE226C, PHE363C, SER374C, TRP269C, TRP269F, TYR281C, TYR316F, TYR317F, VAL261F, VAL263F, VAL267C, VAL267F, VAL283F, VAL314F, VAL36F
• C-G: ARG219C, ARG219G, ASN149C, ASN149G, ASN468C, ASN468G, ASP152C, ASP152G, ASP465C, ASP465G, GLN218C, GLN218G, GLU466C, GLU466G, GLU472C, GLU472G, GLU475C, GLU475G, GLY148C, GLY148G, GLY216G, HIS546C, HIS546G, ILE150C, ILE150G, LEU151C, LEU151G, LEU467C, LEU467G, LYS156C, LYS156G, LYS470C, LYS470G, LYS547C, LYS547G, PRO153C, PRO153G, THR147C
• C-I: ALA450C, ALA450I, ALA566C, ALA566I, ARG192C, ARG587C, ARG587I, ASN182I, ASN287I, ASN288C, ASN288I, ASN313I, ASN446C, ASN447C, ASP191C, ASP191I, ASP284I, ASP286I, ASP293C, ASP293I, ASP299C, ASP526I, ASP559C, ASP561C, ASP561I, ASP563C, ASP585I, ASP586I, GLU189C, GLU189I, GLU295C, GLU295I, GLU310I, GLU381C, GLU389C, GLU445C, GLU451C, GLU451I, GLU525I, GLU562C, GLU562I, GLU570I, GLY187C, GLY187I, GLY387C, GLY449C, GLY567C, GLY567I, HIS296C, HIS296I, HIS453C, HIS453I, HIS560C, HIS560I, ILE290C, ILE290I, ILE294C, ILE300C, LEU568C, LEU568I, LYS188C, LYS188I, LYS190I, LYS193C, LYS285I, LYS289C, LYS289I, LYS312C, LYS312I, LYS452C, LYS591C, LYS591I, MET186I, PHE385C, PHE487C, PHE487I, PRO183I, PRO291C, PRO291I, PRO386C, PRO492C, SER311I, SER448C, SER569I, THR184I, THR489C, THR489I, THR564C, THR564I, VAL185I, VAL314I, VAL388C, VAL565C, VAL565I
• D-E: ALA121D, ALA121E, ALA131D, ALA131E, ALA18D, ALA18E, ALA234D, ALA234E, ALA247D, ALA247E, ARG126D, ARG126E, ARG21D, ARG21E, ARG249D, ARG249E, ARG337D, ARG337E, ARG41D, ARG41E, ARG51D, ARG51E, ASN125D, ASN125E, ASN128D, ASN128E, ASN133D, ASN133E, ASN149D, ASN149E, ASN341D, ASN341E, ASN419D, ASN419E, ASP152D, ASP152E, ASP333D, ASP333E, ASP335D, ASP335E, GLN245D, GLN245E, GLN339D, GLN339E, GLU122D, GLU122E, GLU130D, GLU130E, GLU146D, GLU146E, GLU154D, GLU154E, GLU231D, GLU231E, GLU251D, GLU251E, GLU340D, GLU340E, GLY148D, GLY148E, GLY232D, GLY232E, GLY243D, GLY243E, GLY252D, GLY252E, GLY421D, GLY421E, GLY42D, GLY42E, HIS134D, HIS134E, HIS236D, HIS236E, HIS256D, HIS256E, HIS336D, HIS336E, ILE124D, ILE124E, ILE150D, ILE150E, ILE331D, ILE331E, LEU151D, LEU151E, LEU230D, LEU237D, LEU237E, LEU240D, LEU240E, LEU244D, LEU244E, LEU44D, LEU44E, LYS129D, LYS129E, PHE338D, PHE338E, PRO120D, PRO120E, PRO135D, PRO135E, PRO153D, PRO153E, PRO235D, PRO235E, PRO250D, PRO250E, PRO334D, PRO334E, PRO355D, PRO355E, PRO40D, PRO40E, SER132D, SER132E, SER239D, SER239E, SER242D, SER242E, SER248D, SER248E, SER254D, SER259E, THR123D, THR123E, THR147D, THR147E, THR17D, THR17E, THR20D, THR20E, THR238D, THR238E, THR332D, THR332E, THR43D, THR43E, TYR155D, TYR233D, TYR233E, TYR246D, TYR246E, TYR253D, TYR253E, VAL142D, VAL241D, VAL241E
• D-F: ALA276F, ALA54D, ALA604F, ARG268D, ARG268F, ARG270F, ARG272D, ARG272F, ARG337D, ARG51D, ARG605F, ASN225F, ASN278F, ASN287D, ASN313D, ASP257D, ASP260D, ASP262D, ASP265D, ASP275F, ASP474F, GLN264D, GLU271F, GLU315D, GLU370F, GLU472F, GLU475F, GLU55D, GLU603F, GLU609F, GLY318D, GLY35D, GLY37D, HIS224F, HIS280F, HIS376F, HIS49D, HIS52D, ILE273F, ILE277F, ILE367F, ILE38D, ILE602F, LEU274F, LEU39D, LEU467F, LYS285D, LYS289D, LYS289F, LYS34D, LYS373F, LYS601F, MET279F, PHE226F, PHE363F, PRO40D, SER374F, TRP269D, TRP269F, TYR281F, TYR316D, TYR317D, VAL261D, VAL263D, VAL267D, VAL267F, VAL283D, VAL314D, VAL36D
• D-I: GLY449I, LYS289D
• E-F: ARG219E, ARG219F, ASN149E, ASN149F, ASN468E, ASN468F, ASN469E, ASN469F, ASP152E, ASP152F, ASP465E, ASP465F, GLN218E, GLN218F, GLU466E, GLU466F, GLU472E, GLU472F, GLU475E, GLU475F, GLY148E, GLY148F, GLY216E, GLY216F, HIS546E, HIS546F, ILE150E, ILE150F, LEU151E, LEU151F, LEU217E, LEU217F, LEU467E, LEU467F, LYS156E, LYS156F, LYS470E, LYS470F, LYS547E, LYS547F, PRO153E, PRO153F, THR147E, THR147F, TYR155E, TYR155F
• E-G: ALA276E, ALA50G, ALA54G, ALA56G, ALA604E, ARG268G, ARG270E, ARG272E, ARG272G, ARG337G, ARG51G, ARG605E, ASN225E, ASN278E, ASN287G, ASN313G, ASP257G, ASP260G, ASP262G, ASP265G, ASP275E, ASP335G, ASP474E, GLN264G, GLU271E, GLU271G, GLU315G, GLU370E, GLU472E, GLU475E, GLU55G, GLU603E, GLU609E, GLY35G, GLY37G, HIS224E, HIS280E, HIS376E, HIS49G, HIS52G, ILE221E, ILE273E, ILE277E, ILE367E, ILE38G, LEU274E, LEU39G, LEU467E, LYS285G, LYS289E, LYS289G, LYS34G, LYS373E, LYS380E, LYS601E, MET279E, PHE226E, PHE363E, PRO40G, SER374E, TRP269E, TRP269G, TYR281E, TYR316G, TYR317G, VAL261G, VAL263G, VAL267E, VAL267G, VAL283G, VAL314G, VAL36G
• F-G: ALA121F, ALA121G, ALA131F, ALA131G, ALA18F, ALA18G, ALA234F, ALA234G, ALA247F, ALA247G, ARG126F, ARG126G, ARG21F, ARG21G, ARG249F, ARG249G, ARG337F, ARG337G, ARG41F, ARG41G, ARG51G, ASN125F, ASN125G, ASN128F, ASN128G, ASN133F, ASN133G, ASN149F, ASN149G, ASN341F, ASN341G, ASN419F, ASN419G, ASP152F, ASP152G, ASP333F, ASP333G, ASP335F, ASP335G, GLN245F, GLN245G, GLN339F, GLN339G, GLU122F, GLU122G, GLU130F, GLU130G, GLU146F, GLU146G, GLU154F, GLU154G, GLU231F, GLU231G, GLU251F, GLU251G, GLU340F, GLU340G, GLU85F, GLU85G, GLY148F, GLY148G, GLY232F, GLY232G, GLY243F, GLY243G, GLY252F, GLY421F, GLY421G, GLY42F, GLY42G, HIS134F, HIS134G, HIS15F, HIS15G, HIS236F, HIS236G, HIS256F, HIS256G, HIS336F, HIS336G, ILE124F, ILE124G, ILE140G, ILE150F, ILE150G, ILE331F, ILE331G, LEU151F, LEU151G, LEU19F, LEU237F, LEU237G, LEU240F, LEU240G, LEU244F, LEU244G, LEU44F, LEU44G, LYS129F, LYS129G, PHE338F, PHE338G, PRO120F, PRO120G, PRO135F, PRO135G, PRO153F, PRO153G, PRO235F, PRO235G, PRO250F, PRO250G, PRO334F, PRO334G, PRO355F, PRO40F, PRO40G, SER132F, SER132G, SER239F, SER239G, SER242F, SER242G, SER248F, SER248G, SER254F, SER259F, SER259G, THR123F, THR123G, THR147F, THR147G, THR17F, THR17G, THR20F, THR20G, THR238F, THR238G, THR332F, THR332G, THR43F, THR43G, TYR155F, TYR233F, TYR233G, TYR246F, TYR246G, TYR253F, TYR253G, VAL142F, VAL142G, VAL241F, VAL241G
• F-I: ALA450I, ASN287F, ASN288F, ASN446I, ASN447I, ASP286F, ASP561I, GLU451I, GLY387I, GLY449I, ILE290F, LYS289F, LYS452I, PRO386I, SER448I, VAL283F
• H-I: ALA121H, ALA121I, ALA131I, ALA18H, ALA18I, ALA234H, ALA234I, ALA247H, ALA247I, ARG126H, ARG126I, ARG21H, ARG21I, ARG249H, ARG249I, ARG337H, ARG337I, ARG41H, ARG41I, ARG51H, ASN125H, ASN125I, ASN128I, ASN133H, ASN133I, ASN149H, ASN149I, ASN341H, ASN341I, ASN419H, ASN419I, ASP152H, ASP152I, ASP333H, ASP333I, ASP335H, ASP335I, GLN245H, GLN245I, GLN339H, GLN339I, GLU122H, GLU122I, GLU130H, GLU130I, GLU146H, GLU146I, GLU231H, GLU231I, GLU251H, GLU251I, GLU340H, GLU340I, GLU85H, GLY148H, GLY148I, GLY232H, GLY232I, GLY243H, GLY243I, GLY252H, GLY252I, GLY42H, GLY42I, HIS134H, HIS134I, HIS236H, HIS236I, HIS256H, HIS256I, HIS336H, HIS336I, ILE124H, ILE124I, ILE150H, ILE150I, ILE331H, ILE331I, LEU151H, LEU151I, LEU230H, LEU237H, LEU237I, LEU240H, LEU240I, LEU244H, LEU244I, LEU44H, LEU44I, LYS129H, LYS129I, PHE338H, PHE338I, PRO120H, PRO120I, PRO135H, PRO135I, PRO235H, PRO235I, PRO250H, PRO250I, PRO334H, PRO334I, PRO355I, PRO40H, SER132H, SER132I, SER239H, SER239I, SER242H, SER242I, SER248H, SER248I, SER254H, SER259H, THR123I, THR147H, THR147I, THR17H, THR17I, THR20H, THR20I, THR238H, THR238I, THR332H, THR332I, THR43H, THR43I, TYR233H, TYR233I, TYR246H, TYR246I, TYR253H, TYR253I, VAL142I, VAL241H, VAL241I
• H-J: ARG219H, ARG219J, ASN149H, ASN149J, ASN468H, ASN468J, ASN469H, ASP152H, ASP152J, ASP465H, ASP465J, GLN218H, GLN218J, GLU466H, GLU466J, GLU472H, GLU472J, GLU475H, GLU475J, GLY148H, GLY148J, GLY216H, GLY216J, HIS546H, HIS546J, ILE150H, ILE150J, LEU151H, LEU151J, LEU217H, LEU467H, LEU467J, LYS156H, LYS156J, LYS470H, LYS470J, LYS547H, LYS547J, PRO153H, PRO153J, THR147H, THR147J
• H-K: ALA276H, ALA54K, ALA604H, ARG268H, ARG268K, ARG270H, ARG272H, ARG272K, ARG337K, ARG51K, ARG605H, ASN225H, ASN278H, ASN287K, ASN313K, ASP257K, ASP260K, ASP262K, ASP265K, ASP275H, ASP335K, GLN264K, GLN339K, GLU228H, GLU271H, GLU271K, GLU315K, GLU370H, GLU472H, GLU475H, GLU55K, GLU603H, GLU609H, GLY35K, GLY37K, HIS224H, HIS280H, HIS376H, HIS52K, ILE221H, ILE273H, ILE277H, ILE38K, LEU274H, LEU39K, LEU467H, LYS285K, LYS289H, LYS289K, LYS34K, LYS373H, LYS380H, LYS470H, MET279H, PHE226H, PHE363H, PRO40K, SER374H, TRP269H, TRP269K, TYR281H, TYR316K, TYR317K, VAL261K, VAL263K, VAL267H, VAL267K, VAL283K, VAL36K
• H-M: ARG268H, ARG270M, ARG272H, ASP257H, ASP262H, ASP265H, ASP275M, GLU271H, GLU271M, GLU315H, HIS224M, HIS280M
• I-J: ALA276J, ALA604J, ARG268I, ARG268J, ARG270J, ARG272I, ARG272J, ARG51I, ARG605J, ASN225J, ASN278J, ASN287I, ASN313I, ASP257I, ASP262I, ASP265I, ASP275J, ASP474J, GLN264I, GLU271J, GLU315I, GLU370J, GLU472J, GLU475J, GLU55I, GLU58I, GLU603J, GLU609J, GLY35I, GLY37I, HIS224J, HIS280J, ILE273J, ILE277J, ILE38I, LEU274J, LEU39I, LYS285I, LYS289I, LYS289J, LYS34I, LYS380J, LYS601J, MET279J, PHE226J, PHE363J, PRO377J, PRO40I, SER374J, THR379J, TRP269I, TRP269J, TYR281J, TYR316I, VAL261I, VAL263I, VAL267I, VAL267J, VAL283I, VAL36I
• I-L: ALA604I, ARG268L, ARG270I, ARG272L, ARG605I, ASP257L, ASP262L, ASP265L, ASP275I, GLU271I, GLU271L, GLU315L, GLU603I, GLU609I, GLY35L, GLY37L, HIS224I, HIS280I, ILE38L, LEU39L, LYS285L, LYS34L, PRO40L, VAL36L
• I-M: HIS546I, HIS546M, LYS547I, LYS547M
• J-K: ALA121J, ALA121K, ALA131J, ALA131K, ALA18J, ALA18K, ALA234J, ALA234K, ALA247J, ALA247K, ARG126J, ARG126K, ARG21J, ARG21K, ARG249J, ARG249K, ARG337J, ARG337K, ARG41J, ARG41K, ARG51J, ARG51K, ASN125J, ASN125K, ASN128J, ASN128K, ASN133J, ASN133K, ASN149J, ASN149K, ASN341J, ASN341K, ASN419J, ASN419K, ASP152J, ASP152K, ASP333J, ASP333K, ASP335J, ASP335K, GLN245J, GLN245K, GLN339J, GLN339K, GLU122J, GLU122K, GLU130J, GLU130K, GLU146J, GLU146K, GLU154J, GLU154K, GLU231J, GLU231K, GLU251J, GLU251K, GLU340J, GLU340K, GLU85J, GLY148J, GLY148K, GLY232J, GLY232K, GLY243J, GLY243K, GLY252J, GLY252K, GLY421J, GLY421K, GLY42J, GLY42K, HIS134J, HIS134K, HIS15J, HIS15K, HIS236J, HIS236K, HIS256J, HIS256K, HIS336J, HIS336K, ILE124J, ILE124K, ILE140K, ILE150J, ILE150K, ILE331J, ILE331K, ILE418J, LEU151J, LEU151K, LEU19J, LEU230J, LEU237J, LEU237K, LEU240J, LEU240K, LEU244J, LEU244K, LEU44J, LEU44K, LYS129J, LYS129K, PHE338J, PHE338K, PHE420J, PHE420K, PRO120J, PRO120K, PRO135J, PRO135K, PRO153J, PRO153K, PRO235J, PRO235K, PRO250J, PRO250K, PRO334J, PRO334K, PRO355J, PRO355K, PRO40J, PRO40K, SER132J, SER132K, SER239J, SER239K, SER242J, SER242K, SER248J, SER248K, SER254J, SER259J, SER259K, THR123J, THR123K, THR147J, THR147K, THR17J, THR17K, THR20J, THR20K, THR238J, THR238K, THR332J, THR332K, THR422J, THR422K, THR43J, THR43K, TYR155J, TYR155K, TYR233J, TYR233K, TYR246J, TYR246K, TYR253J, TYR253K, VAL142J, VAL142K, VAL241J, VAL241K
• J-L: ARG268J, ARG270L, ARG272J, ARG51J, ARG605L, ASP257J, ASP262J, ASP265J, ASP275L, GLN264J, GLU271L, GLU315J, GLU370L, GLU472L, GLU55J, HIS224L, HIS280L, LYS285J, LYS373L
• K-L: HIS546K, HIS546L, LYS547K, LYS547L
• K-M: ARG268M, ARG270K, ARG272M, ARG605K, ASP257M, ASP262M, ASP265M, ASP275K, GLN264M, GLU271K, GLU271M, GLU315M, GLY35M, HIS224K
• L-M: ARG21L, ARG249M, ARG337L, ARG337M, ASN125L, ASN125M, ASP152L, ASP152M, ASP333L, ASP333M, ASP335L, ASP335M, GLU251L, GLU251M, GLU340L, GLU340M, HIS236L, LYS129L, LYS129M, PHE338M, SER242L, SER242M, VAL241M