3IV1

coiled-coil domain of tumor susceptibility gene 101

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 97
  • Norm. En. per Res.: -3.8047
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-42.2569	-62.9915	-216.453	-321.7014	102	11	6	9733	10	76	67
A-C	-7.1804	-75.7105	-271.088	-353.9789	128	9	17	12438	6	70	65
A-D	0.0	15.6537	-30.607	-14.9533	46	5	1	1805	0	17	24
A-E	0.0	0.0	-0.2957	-0.2957	8	0	0	87	0	0	3
B-C	0.0	15.8013	-32.542	-16.7407	45	6	1	1883	0	16	23
B-D	-7.4806	-68.651	-260.414	-336.5457	127	11	17	12322	5	70	64
C-D	-41.8542	-111.2035	-215.997	-369.0547	97	9	6	9397	13	73	68
C-E	0.0	0.0	-0.0403	-0.0403	3	0	0	15	0	2	0
C-F	0.0	-28.732	-9.3496	-38.0816	20	3	0	713	2	14	18
C-G	0.0	1.879	-12.4199	-10.5409	14	0	0	584	0	18	13
D-F	0.0	0.0	-0.0424	-0.0424	9	0	0	25	0	6	4
D-G	0.0	0.0	-0.0236	-0.0236	6	0	0	13	0	6	4
E-F	-8.2113	-86.343	-274.861	-369.4152	128	11	17	12278	6	70	64
G-H	-6.4613	-77.745	-262.426	-346.6323	127	9	17	12081	3	70	64

Interface residues

• A-B: ALA233B, ALA249A, ALA249B, ALA251A, ALA251B, ALA282A, ALA282B, ARG239A, ARG239B, ARG241A, ARG241B, ARG248A, ARG248B, ARG258A, ARG276A, ARG276B, ASN254A, ASN254B, ASN287A, ASN287B, ASP236A, ASP236B, ASP247A, ASP247B, ASP278A, ASP278B, ASP285A, ASP285B, GLN250A, GLN250B, GLN268A, GLN268B, GLN279A, GLN279B, GLU244A, GLU244B, GLU245A, GLU245B, GLU252A, GLU252B, GLU260A, GLU260B, GLU261A, GLU261B, GLU271A, GLU271B, GLU272A, GLU272B, GLU280A, GLU280B, GLU283A, GLU283B, GLU289A, GLU289B, GLY266A, GLY266B, HIS267A, HIS267B, ILE288A, ILE288B, LEU238A, LEU238B, LEU253A, LEU253B, LEU256A, LEU256B, LEU263A, LEU263B, LEU270A, LEU270B, LEU277A, LEU277B, LYS243A, LYS243B, LYS257A, LYS257B, LYS264A, LYS264B, LYS265A, LYS265B, LYS269A, LYS269B, LYS286A, LYS286B, LYS292A, LYS292B, SER232A, SER232B, SER235A, SER235B, THR259A, THR259B, THR275A, THR275B, TRP240A, TRP240B, VAL274A, VAL274B, VAL281A, VAL281B, VAL284A, VAL284B
• A-C: ALA233A, ALA233C, ALA249A, ALA249C, ALA251A, ALA251C, ALA255A, ALA255C, ALA282A, ALA282C, ARG239A, ARG239C, ARG241A, ARG241C, ARG248A, ARG248C, ARG258A, ARG258C, ARG276A, ARG276C, ASN254A, ASN254C, ASN287A, ASN287C, ASP236A, ASP236C, ASP262A, ASP262C, ASP278A, ASP278C, ASP285A, ASP285C, ASP295A, ASP295C, GLN250A, GLN250C, GLN268A, GLN268C, GLN279A, GLN279C, GLU244A, GLU244C, GLU245A, GLU245C, GLU252A, GLU252C, GLU260A, GLU260C, GLU261A, GLU261C, GLU271A, GLU271C, GLU272A, GLU272C, GLU280A, GLU280C, GLU283A, GLU283C, GLU289A, GLU289C, GLY266A, GLY266C, HIS267A, HIS267C, ILE231A, ILE231C, ILE288A, ILE288C, LEU230A, LEU230C, LEU238A, LEU238C, LEU253A, LEU253C, LEU256A, LEU256C, LEU263A, LEU263C, LEU270A, LEU270C, LEU277A, LEU277C, LEU290A, LEU290C, LEU291A, LEU291C, LEU298A, LEU298C, LYS237A, LYS237C, LYS243A, LYS243C, LYS257A, LYS257C, LYS264A, LYS264C, LYS265A, LYS265C, LYS269A, LYS269C, LYS286A, LYS286C, LYS292A, LYS292C, LYS293A, LYS293C, LYS294A, LYS294C, SER228A, SER228C, SER229A, SER229C, SER232A, SER232C, SER235A, SER235C, THR259A, THR259C, TRP240A, TRP240C, VAL234A, VAL234C, VAL274A, VAL274C, VAL281A, VAL281C, VAL284A, VAL284C
• A-D: ALA249A, ALA249D, ARG239A, ARG239D, ASP236A, ASP236D, GLU252A, GLU252D, GLU260A, GLU260D, GLU271A, GLU271D, GLY266A, GLY266D, HIS267A, HIS267D, ILE231A, ILE231D, LEU238A, LEU238D, LEU253A, LEU253D, LEU256A, LEU256D, LEU263A, LEU263D, LEU270A, LEU270D, LEU277A, LEU277D, LYS243A, LYS243D, LYS264A, LYS264D, SER232A, SER232D, SER235A, SER235D, THR259A, THR259D, TRP240A, VAL234A, VAL234D, VAL274A, VAL274D, VAL281A
• A-E: ARG241A, ARG241E, ARG248A, ARG248E, LYS237A, LYS237E, TRP240A, TRP240E
• B-C: ALA249B, ALA249C, ARG239B, ARG239C, ASP236B, ASP236C, GLU252B, GLU260B, GLU260C, GLU271B, GLU271C, GLY266B, GLY266C, HIS267B, HIS267C, ILE231B, ILE231C, LEU238B, LEU238C, LEU253B, LEU253C, LEU256B, LEU256C, LEU263B, LEU263C, LEU270B, LEU270C, LEU277B, LEU277C, LYS243B, LYS243C, LYS264B, LYS264C, SER232B, SER232C, SER235B, SER235C, THR259B, THR259C, TRP240B, VAL234B, VAL234C, VAL274B, VAL274C, VAL281B
• B-D: ALA233B, ALA233D, ALA249B, ALA249D, ALA251B, ALA251D, ALA255B, ALA255D, ALA282B, ALA282D, ARG239B, ARG239D, ARG241B, ARG241D, ARG248B, ARG248D, ARG258B, ARG258D, ARG276B, ARG276D, ASN254B, ASN254D, ASN287B, ASN287D, ASP236B, ASP236D, ASP262B, ASP262D, ASP278B, ASP278D, ASP285B, ASP285D, ASP295B, ASP295D, GLN250B, GLN250D, GLN268B, GLN268D, GLN279B, GLN279D, GLU244B, GLU244D, GLU245B, GLU245D, GLU252B, GLU252D, GLU260B, GLU260D, GLU261B, GLU261D, GLU271B, GLU271D, GLU272B, GLU272D, GLU280B, GLU280D, GLU283B, GLU283D, GLU289B, GLU289D, GLY266B, GLY266D, HIS267B, HIS267D, ILE231B, ILE231D, ILE288B, ILE288D, LEU230B, LEU230D, LEU238B, LEU238D, LEU253B, LEU253D, LEU256B, LEU256D, LEU263B, LEU263D, LEU270B, LEU270D, LEU277B, LEU277D, LEU290B, LEU290D, LEU291B, LEU291D, LEU298B, LEU298D, LYS237B, LYS237D, LYS243B, LYS243D, LYS257B, LYS257D, LYS264B, LYS264D, LYS265B, LYS265D, LYS269B, LYS269D, LYS286B, LYS286D, LYS292B, LYS292D, LYS293B, LYS293D, LYS294B, LYS294D, SER228B, SER228D, SER229B, SER229D, SER232B, SER232D, SER235B, SER235D, THR259B, THR259D, TRP240B, VAL234B, VAL234D, VAL274B, VAL274D, VAL281B, VAL281D, VAL284B, VAL284D
• C-D: ALA249C, ALA249D, ALA251C, ALA251D, ALA282C, ALA282D, ARG239C, ARG239D, ARG241C, ARG241D, ARG248C, ARG248D, ASN254C, ASN254D, ASN287C, ASN287D, ASP236C, ASP236D, ASP247C, ASP247D, ASP278C, ASP278D, ASP285C, ASP285D, GLN250C, GLN250D, GLN268C, GLN268D, GLN279C, GLN279D, GLU244C, GLU244D, GLU245C, GLU245D, GLU252C, GLU252D, GLU260C, GLU260D, GLU261C, GLU261D, GLU271C, GLU271D, GLU272C, GLU272D, GLU280C, GLU280D, GLU283C, GLU283D, GLU289C, GLU289D, GLY266C, GLY266D, HIS267C, HIS267D, ILE288C, ILE288D, LEU238C, LEU238D, LEU253C, LEU253D, LEU256C, LEU256D, LEU263C, LEU263D, LEU270C, LEU270D, LEU277C, LEU277D, LYS243C, LYS243D, LYS257C, LYS257D, LYS264C, LYS264D, LYS265C, LYS265D, LYS269C, LYS269D, LYS286C, LYS286D, LYS292D, SER232C, SER232D, SER235C, SER235D, THR259C, THR259D, THR275C, THR275D, TRP240C, TRP240D, VAL274C, VAL274D, VAL281C, VAL281D, VAL284C, VAL284D
• C-E: ARG248E, ARG276C, GLU272C
• C-F: ALA251C, ALA251F, ALA255C, ARG258C, ARG258F, ASN254C, ASN254F, ASP262C, ASP262F, GLN250C, GLN250F, GLU261C, GLU261F, LYS243C, LYS243F, LYS257C, LYS265C, LYS265F, LYS269C, LYS269F
• C-G: GLU289G, GLU296C, GLU296G, GLU303C, GLU303G, LEU302C, LEU302G, LYS292C, LYS292G, LYS293C, LYS293G, LYS304C, LYS304G, SER299C
• D-F: ALA233F, ALA282D, ASP236F, ASP278D, LYS243F, LYS286D, LYS293D, SER229F, TRP240F
• D-G: ALA233D, ASP236D, LYS286G, LYS293G, SER229D, TRP240D
• E-F: ALA233E, ALA233F, ALA249E, ALA249F, ALA251E, ALA251F, ALA255E, ALA255F, ALA282E, ALA282F, ARG239E, ARG239F, ARG241E, ARG241F, ARG248E, ARG248F, ARG258E, ARG258F, ARG276E, ARG276F, ASN254E, ASN254F, ASN287E, ASN287F, ASP236E, ASP236F, ASP262E, ASP262F, ASP278E, ASP278F, ASP285E, ASP285F, ASP295E, ASP295F, GLN250E, GLN250F, GLN268E, GLN268F, GLN279E, GLN279F, GLU244E, GLU244F, GLU245E, GLU245F, GLU252E, GLU252F, GLU260E, GLU260F, GLU261E, GLU261F, GLU271E, GLU271F, GLU272E, GLU272F, GLU280E, GLU280F, GLU283E, GLU283F, GLU289E, GLU289F, GLY266E, GLY266F, HIS267E, HIS267F, ILE231E, ILE231F, ILE288E, ILE288F, LEU230E, LEU230F, LEU238E, LEU238F, LEU253E, LEU253F, LEU256E, LEU256F, LEU263E, LEU263F, LEU270E, LEU270F, LEU277E, LEU277F, LEU290E, LEU290F, LEU291E, LEU291F, LEU298E, LEU298F, LYS237E, LYS237F, LYS243E, LYS243F, LYS257E, LYS257F, LYS264E, LYS264F, LYS265E, LYS265F, LYS269E, LYS269F, LYS286E, LYS286F, LYS292E, LYS292F, LYS293E, LYS293F, LYS294E, LYS294F, SER228E, SER228F, SER229E, SER229F, SER232E, SER232F, SER235E, SER235F, THR259E, THR259F, TRP240E, TRP240F, VAL234E, VAL234F, VAL274E, VAL274F, VAL281E, VAL281F, VAL284E, VAL284F
• G-H: ALA233G, ALA233H, ALA249G, ALA249H, ALA251G, ALA251H, ALA255G, ALA255H, ALA282G, ALA282H, ARG239G, ARG239H, ARG241G, ARG241H, ARG248G, ARG248H, ARG258G, ARG258H, ARG276G, ARG276H, ASN254G, ASN254H, ASN287G, ASN287H, ASP236G, ASP236H, ASP262G, ASP262H, ASP278G, ASP278H, ASP285G, ASP285H, ASP295G, ASP295H, GLN250G, GLN250H, GLN268G, GLN268H, GLN279G, GLN279H, GLU244G, GLU244H, GLU245G, GLU245H, GLU252G, GLU252H, GLU260G, GLU260H, GLU261G, GLU261H, GLU271G, GLU271H, GLU272G, GLU272H, GLU280G, GLU280H, GLU283G, GLU283H, GLU289G, GLU289H, GLY266G, GLY266H, HIS267G, HIS267H, ILE231G, ILE231H, ILE288G, ILE288H, LEU230G, LEU230H, LEU238G, LEU238H, LEU253G, LEU253H, LEU256G, LEU256H, LEU263G, LEU263H, LEU270G, LEU270H, LEU277G, LEU277H, LEU290G, LEU290H, LEU291G, LEU291H, LEU298G, LEU298H, LYS237G, LYS237H, LYS243G, LYS243H, LYS257G, LYS257H, LYS264G, LYS264H, LYS265G, LYS265H, LYS269G, LYS269H, LYS286G, LYS286H, LYS292G, LYS292H, LYS293H, LYS294G, LYS294H, SER228G, SER228H, SER229G, SER229H, SER232G, SER232H, SER235G, SER235H, THR259G, THR259H, TRP240G, TRP240H, VAL234G, VAL234H, VAL274G, VAL274H, VAL281G, VAL281H, VAL284G, VAL284H