3ISS

crystal structure of enolpyruvyl-udp-glcnac synthase (mura):udp-n- acetylmuramic acid:phosphite from escherichia coli

• Total interactions analyzed: 66
• Total true interactions: 26
• Strongest Interaction:
  • Chains: I-K
  • Int. Res.: 44
  • Norm. En. per Res.: -3.0855
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-34.9324	0.128	-173.416	-208.2204	137	18	4	9630	0	42	44
A-D	0.0	7.6253	-23.9911	-16.3658	27	2	0	1236	0	19	17
A-E	-4.3608	-54.9849	-77.753	-137.0987	46	4	2	3472	4	6	11
A-H	-18.3561	-36.8253	-117.947	-173.1284	94	2	4	5612	6	52	46
B-E	-41.4559	-26.2533	-122.513	-190.2222	100	12	4	6112	5	53	43
B-H	0.0	-52.951	-82.3193	-135.2703	46	8	3	3676	4	6	12
C-D	-45.9889	-1.2152	-198.936	-246.1401	140	14	4	10086	0	44	43
C-F	-2.8032	-45.6863	-64.1898	-112.6793	44	6	2	3264	2	6	11
C-G	-7.1149	-55.0422	-121.53	-183.6872	92	4	4	5837	5	50	46
C-K	-13.9336	-8.8438	-54.3411	-77.1186	44	0	0	2067	1	23	27
D-F	-26.5856	-27.6558	-99.6863	-153.9276	96	7	4	5404	4	50	43
D-G	0.0	-45.2165	-48.3771	-93.5935	41	0	1	2584	2	6	10
E-H	-68.3566	0.9374	-211.126	-278.5452	141	17	4	10489	0	44	44
E-J	-15.7504	-10.145	-31.9254	-57.8208	42	5	0	1590	4	33	32
E-K	-8.4805	-4.417	-17.7365	-30.634	31	3	0	1334	1	7	13
F-G	-60.1193	1.9717	-219.39	-277.5376	145	17	4	10584	0	44	43
F-H	0.0	-26.6605	-25.9778	-52.6383	26	2	0	1253	1	20	16
G-K	0.0	5.5682	-6.3198	-0.7517	29	0	0	714	0	15	14
H-J	0.0	0.0	-0.0268	-0.0268	4	0	0	9	0	2	1
H-K	-7.4182	-14.5332	-5.0606	-27.012	10	1	0	134	1	4	4
I-J	-53.3159	1.4499	-200.334	-252.2	136	13	4	9908	0	44	43
I-K	-13.5619	-58.9843	-63.2146	-135.7609	44	2	2	3031	4	6	11
I-L	-2.6362	-57.6806	-72.1237	-132.4405	89	0	4	4407	6	47	44
J-K	-19.4476	-45.6337	-94.0388	-159.1201	89	0	4	5015	4	50	43
J-L	0.0	-48.4344	-49.8034	-98.2378	41	0	2	2634	4	6	10
K-L	-71.1533	-1.0595	-230.679	-302.8917	149	24	4	10976	0	44	44

Interface residues

• A-B: ALA119A, ALA119B, ALA343A, ALA343B, ALA345A, ALA345B, ALA363A, ALA363B, ALA367A, ARG120A, ARG120B, ARG331A, ARG331B, ARG340A, ARG340B, ARG391A, ARG391B, ARG91A, ARG91B, ASN330A, ASN330B, ASN350A, ASN350B, ASP123A, ASP123B, ASP390A, ASP390B, ASP85A, ASP85B, CYS115A, CYS115B, GLN364A, GLN364B, GLU139A, GLU139B, GLU140A, GLU140B, GLU329A, GLU329B, GLU337A, GLU337B, GLU346A, GLU346B, GLU348A, GLU348B, GLU384A, GLY113A, GLY113B, GLY114A, GLY114B, GLY118A, GLY118B, GLY141A, GLY141B, GLY342A, GLY342B, GLY362A, GLY362B, GLY385A, GLY385B, HIS334A, HIS334B, HIS344A, HIS344B, ILE117A, ILE117B, ILE347A, ILE347B, LEU111A, LEU111B, LEU138A, LEU138B, LEU338A, LEU338B, LYS160A, LYS160B, LYS3A, LYS3B, LYS88A, LYS88B, MET1A, MET1B, MET333A, MET333B, MET341A, MET341B, MET366A, MET366B, PHE328A, PHE328B, PHE332A, PHE332B, PRO112A, PRO112B, PRO121A, PRO121B, PRO336A, PRO336B, PRO83A, PRO83B, SER110A, SER110B, SER339A, SER339B, SER349A, SER349B, SER361A, SER361B, THR116A, THR116B, THR368A, THR368B, THR386A, THR386B, THR387A, THR387B, THR89A, THR89B, TYR142A, TYR142B, TYR393B, TYR84A, TYR84B, VAL109A, VAL109B, VAL122A, VAL122B, VAL143A, VAL143B, VAL335A, VAL335B, VAL365A, VAL365B, VAL388A, VAL388B, VAL87A, VAL87B
• A-D: ALA134D, ARG150D, ARG246A, ARG288A, ASP148D, ASP272A, ASP283A, GLN13A, GLU177D, GLU219D, GLU318A, GLU358A, GLY133D, GLY149D, GLY178D, GLY247A, GLY286A, HIS285A, LEU151D, LYS11A, LYS152D, LYS248A, LYS287A, LYS290A, MET284A, THR135D, VAL147D
• A-E: ALA291E, ALA345A, ALA345E, ARG295A, ARG295E, ASN293A, ASN293E, ASN350A, ASN350E, CYS354A, CYS354E, GLU325A, GLU325E, GLU329E, GLU346A, GLU346E, GLU348A, GLU348E, GLY319A, GLY319E, GLY321A, GLY321E, HIS355A, HIS355E, ILE323A, ILE323E, ILE347A, ILE347E, ILE353A, ILE353E, PHE322A, PHE322E, SER349A, SER349E, THR320A, THR320E, THR324A, THR324E, THR326A, THR326E, THR351A, THR351E, VAL294A, VAL294E, VAL352A, VAL352E
• A-H: ALA185A, ALA185H, ALA186A, ALA186H, ALA261A, ALA261H, ALA264A, ALA264H, ALA297A, ALA297H, ALA301A, ALA301H, ARG187A, ARG187H, ARG212A, ARG212H, ARG267A, ARG267H, ARG295A, ARG295H, ASN184A, ASN184H, ASN293A, ASN293H, ASN350A, ASN350H, ASP159A, ASP159H, ASP211A, ASP211H, ASP257A, ASP257H, ASP260A, ASP260H, ASP268A, ASP268H, GLN131A, GLN131H, GLU183A, GLU183H, GLU329A, GLU329H, GLY209A, GLY209H, HIS155A, HIS155H, HIS299A, HIS299H, ILE156A, ILE156H, ILE181A, ILE181H, ILE182A, ILE182H, LEU124A, LEU124H, LEU259A, LEU259H, LEU263A, LEU263H, LYS160A, LYS160H, LYS265A, LYS265H, MET158A, MET158H, PHE302A, PHE302H, PHE322A, PHE322H, PRO256A, PRO256H, PRO298A, PRO298H, PRO300A, PRO300H, THR210A, THR210H, THR296A, THR296H, THR324A, THR324H, THR326A, THR326H, VAL157A, VAL157H, VAL161A, VAL161H, VAL262A, VAL262H, VAL294A, VAL294H, VAL327A, VAL327H
• B-E: ALA185B, ALA185E, ALA186B, ALA186E, ALA261B, ALA261E, ALA264B, ALA264E, ALA297B, ALA297E, ALA301B, ALA301E, ARG187B, ARG187E, ARG212B, ARG212E, ARG267B, ARG267E, ARG295B, ARG295E, ASN184B, ASN184E, ASN293B, ASN293E, ASN350B, ASN350E, ASP159B, ASP159E, ASP211B, ASP211E, ASP257B, ASP257E, ASP260B, ASP260E, ASP268B, ASP268E, GLN131B, GLN131E, GLU183B, GLU183E, GLU329B, GLU329E, GLY209B, GLY209E, HIS155B, HIS155E, HIS299B, HIS299E, ILE156B, ILE156E, ILE181B, ILE181E, LEU124B, LEU124E, LEU259B, LEU259E, LEU263B, LEU263E, LYS160B, LYS160E, LYS265B, LYS265E, MET158B, MET158E, PHE302B, PHE302E, PHE322B, PHE322E, PRO256B, PRO256E, PRO298B, PRO298E, PRO300B, PRO300E, SER127E, SER349B, SER349E, THR210B, THR210E, THR258B, THR296B, THR296E, THR324B, THR324E, THR326B, THR326E, VAL157B, VAL157E, VAL161B, VAL161E, VAL262B, VAL262E, VAL275B, VAL275E, VAL292B, VAL292E, VAL294B, VAL294E, VAL327B, VAL327E
• B-H: ALA291B, ALA291H, ALA345B, ALA345H, ARG295B, ARG295H, ASN293B, ASN293H, ASN350B, ASN350H, CYS354B, CYS354H, GLU325B, GLU325H, GLU346B, GLU346H, GLU348B, GLU348H, GLY319B, GLY319H, GLY321B, GLY321H, HIS355B, HIS355H, ILE323B, ILE323H, ILE347B, ILE347H, ILE353B, ILE353H, PHE322B, PHE322H, SER349B, SER349H, THR320B, THR320H, THR324B, THR324H, THR326B, THR326H, THR351B, THR351H, VAL294B, VAL294H, VAL352B, VAL352H
• C-D: ALA119C, ALA119D, ALA343C, ALA343D, ALA345C, ALA345D, ALA363C, ALA363D, ALA367D, ALA82C, ARG120C, ARG120D, ARG331C, ARG331D, ARG340C, ARG340D, ARG391C, ARG391D, ARG91C, ARG91D, ASN330C, ASN330D, ASN350C, ASN350D, ASP123C, ASP123D, ASP390C, ASP390D, ASP85C, ASP85D, CYS115C, CYS115D, GLN364C, GLN364D, GLU139C, GLU139D, GLU140C, GLU140D, GLU329C, GLU329D, GLU337C, GLU337D, GLU346C, GLU346D, GLU348C, GLU348D, GLU384C, GLU384D, GLY113C, GLY113D, GLY114C, GLY114D, GLY118C, GLY118D, GLY141C, GLY141D, GLY342C, GLY342D, GLY362C, GLY362D, GLY385C, GLY385D, HIS334C, HIS334D, HIS344C, HIS344D, ILE117C, ILE117D, ILE347C, ILE347D, LEU111C, LEU111D, LEU138C, LEU138D, LEU338C, LEU338D, LYS160C, LYS160D, LYS3C, LYS3D, LYS88C, LYS88D, MET1C, MET1D, MET333C, MET333D, MET341C, MET341D, MET366C, MET366D, PHE328C, PHE332C, PHE332D, PRO112C, PRO112D, PRO121C, PRO121D, PRO336C, PRO336D, PRO83C, PRO83D, SER110C, SER110D, SER339C, SER339D, SER349C, SER349D, SER361C, SER361D, THR116C, THR116D, THR368C, THR368D, THR386C, THR386D, THR387D, THR89C, THR89D, TYR142C, TYR142D, TYR393C, TYR393D, TYR84C, TYR84D, VAL109C, VAL109D, VAL122C, VAL122D, VAL143C, VAL143D, VAL335C, VAL335D, VAL365C, VAL365D, VAL388C, VAL388D, VAL389C, VAL389D, VAL87C, VAL87D
• C-F: ALA291F, ALA345C, ALA345F, ARG295C, ARG295F, ASN293C, ASN293F, ASN350C, ASN350F, CYS354C, CYS354F, GLU325C, GLU325F, GLU346C, GLU346F, GLU348C, GLU348F, GLY319C, GLY319F, GLY321C, GLY321F, HIS355C, HIS355F, ILE323C, ILE323F, ILE347C, ILE347F, ILE353C, ILE353F, PHE322C, PHE322F, SER349C, SER349F, THR320C, THR320F, THR324C, THR324F, THR326C, THR351C, THR351F, VAL294C, VAL294F, VAL352C, VAL352F
• C-G: ALA185C, ALA185G, ALA186C, ALA186G, ALA261C, ALA261G, ALA264C, ALA264G, ALA297C, ALA297G, ALA301C, ALA301G, ARG187C, ARG187G, ARG212C, ARG212G, ARG267C, ARG267G, ARG295C, ARG295G, ASN184C, ASN184G, ASN293C, ASN293G, ASP159C, ASP159G, ASP211C, ASP211G, ASP257C, ASP257G, ASP260C, ASP260G, ASP268C, ASP268G, GLN131C, GLN131G, GLU183C, GLU183G, GLU329C, GLU329G, GLY209C, GLY209G, HIS155C, HIS155G, HIS299C, HIS299G, ILE156C, ILE156G, ILE181C, ILE181G, ILE182C, ILE182G, LEU124C, LEU124G, LEU259C, LEU259G, LEU263C, LEU263G, LYS160C, LYS160G, LYS265C, LYS265G, MET158C, MET158G, PHE302C, PHE302G, PHE322C, PHE322G, PRO256C, PRO256G, PRO298C, PRO298G, PRO300C, PRO300G, THR210C, THR210G, THR258C, THR258G, THR296C, THR296G, THR324C, THR324G, THR326C, THR326G, VAL157C, VAL157G, VAL161C, VAL161G, VAL262C, VAL262G, VAL294C, VAL294G
• C-K: ALA102K, ALA145K, ALA271C, ARG103K, ARG150K, ARG220K, ARG246C, ARG267C, ARG288C, ASN78K, ASP148K, ASP268C, ASP272C, ASP283C, GLN106K, GLN108K, GLN13C, GLU139K, GLU274C, GLU318C, GLU36K, GLY105K, GLY107K, GLY149K, GLY247C, GLY270C, GLY286C, HIS285C, ILE273C, LEU100K, LEU175K, LYS11C, LYS137K, LYS144K, LYS248C, LYS287C, LYS290C, MET284C, PHE104K, PHE80K, SER146K, THR135K, VAL101K, VAL147K
• D-F: ALA185D, ALA185F, ALA186D, ALA186F, ALA261D, ALA261F, ALA264D, ALA264F, ALA297D, ALA297F, ALA301D, ALA301F, ARG187D, ARG187F, ARG212D, ARG212F, ARG267D, ARG267F, ARG295D, ARG295F, ASN184D, ASN184F, ASN293D, ASN293F, ASN350D, ASN350F, ASP159D, ASP159F, ASP211D, ASP211F, ASP257D, ASP257F, ASP260D, ASP260F, ASP268D, ASP268F, GLN131D, GLN131F, GLU183D, GLU183F, GLU329D, GLU329F, GLY209D, GLY209F, HIS155D, HIS155F, HIS299D, HIS299F, ILE156D, ILE156F, ILE181D, ILE181F, LEU124D, LEU124F, LEU259D, LEU259F, LEU263D, LEU263F, LYS160D, LYS160F, LYS265D, LYS265F, MET158D, MET158F, PHE302D, PHE302F, PHE322D, PHE322F, PRO256F, PRO298D, PRO298F, PRO300D, PRO300F, SER162D, SER349D, SER349F, THR210D, THR210F, THR296D, THR324D, THR324F, THR326D, THR326F, VAL157D, VAL157F, VAL161D, VAL161F, VAL262D, VAL262F, VAL275F, VAL292D, VAL292F, VAL294D, VAL294F, VAL327D, VAL327F
• D-G: ALA345D, ARG295D, ARG295G, ASN293D, ASN293G, ASN350D, ASN350G, CYS354D, CYS354G, GLU325D, GLU325G, GLU346D, GLU346G, GLU348D, GLU348G, GLY319G, GLY321D, GLY321G, HIS355D, HIS355G, ILE323D, ILE323G, ILE347D, ILE347G, ILE353D, ILE353G, PHE322D, PHE322G, SER349D, SER349G, THR320D, THR320G, THR324D, THR324G, THR326D, THR326G, THR351D, THR351G, VAL294D, VAL352D, VAL352G
• E-H: ALA119E, ALA119H, ALA343E, ALA343H, ALA345E, ALA345H, ALA363E, ALA363H, ALA367E, ALA367H, ARG120E, ARG120H, ARG331E, ARG331H, ARG340E, ARG340H, ARG391E, ARG391H, ARG91E, ARG91H, ASN330E, ASN330H, ASN350E, ASN350H, ASP123E, ASP123H, ASP390E, ASP390H, ASP85E, ASP85H, CYS115E, CYS115H, GLN364E, GLN364H, GLU139E, GLU139H, GLU140E, GLU140H, GLU329E, GLU329H, GLU337E, GLU337H, GLU346E, GLU346H, GLU348E, GLU348H, GLU384E, GLU384H, GLY113E, GLY113H, GLY114E, GLY114H, GLY118E, GLY118H, GLY141E, GLY141H, GLY342E, GLY342H, GLY362E, GLY362H, GLY385E, GLY385H, HIS334E, HIS334H, HIS344E, HIS344H, ILE117E, ILE117H, ILE347E, ILE347H, LEU111E, LEU111H, LEU138E, LEU138H, LEU338E, LEU338H, LEU376H, LYS160E, LYS160H, LYS3E, LYS3H, LYS88E, LYS88H, MET1E, MET1H, MET333E, MET333H, MET341E, MET341H, MET366E, MET366H, PHE328E, PHE332E, PHE332H, PRO112E, PRO112H, PRO121E, PRO121H, PRO336E, PRO336H, PRO83E, PRO83H, SER110E, SER110H, SER339E, SER339H, SER349E, SER349H, SER361E, SER361H, THR116E, THR116H, THR368E, THR368H, THR386E, THR386H, THR387H, THR89E, THR89H, TYR142E, TYR142H, TYR393E, TYR393H, TYR84E, TYR84H, VAL109E, VAL109H, VAL122E, VAL122H, VAL143E, VAL143H, VAL335E, VAL335H, VAL365E, VAL365H, VAL388E, VAL388H, VAL389E, VAL389H, VAL87E, VAL87H
• E-J: ALA254J, ALA408E, ARG227J, ARG252J, ARG401E, ARG407E, ARG415E, ARG66E, ASN196J, ASN253J, ASP257J, ASP278J, ASP396E, ASP404E, ASP67E, GLN255J, GLN42J, GLU274J, GLU277J, GLU400E, GLU403E, GLU40J, GLU414E, GLU65E, GLY224J, GLY276J, ILE392E, ILE402E, ILE413E, LYS405E, LYS417E, LYS46E, LYS55E, PHE4E, PRO256J, SER58E, THR200J, TRP279J, VAL192J, VAL225J, VAL275J, VAL416E
• E-K: ALA363E, ARG212K, ARG415E, ARG5E, ASN412E, GLN7E, GLU183K, GLU216K, GLU414E, GLY178K, GLY207K, GLY217K, GLY362E, GLY385E, GLY418E, HIS155K, ILE181K, ILE205K, ILE213K, ILE215K, LYS204K, LYS417E, SER206K, THR179K, THR180K, THR386E, THR387E, VAL214K, VAL388E, VAL416E, VAL6E
• F-G: ALA119F, ALA119G, ALA343F, ALA343G, ALA345F, ALA345G, ALA363F, ALA363G, ALA367F, ALA367G, ALA82F, ALA82G, ARG120F, ARG120G, ARG331F, ARG331G, ARG340F, ARG340G, ARG391F, ARG391G, ARG91F, ARG91G, ASN330F, ASN330G, ASN350F, ASN350G, ASP123F, ASP123G, ASP390F, ASP390G, ASP85F, ASP85G, CYS115F, CYS115G, GLN364F, GLN364G, GLU139F, GLU139G, GLU140F, GLU140G, GLU329F, GLU329G, GLU337F, GLU337G, GLU346F, GLU346G, GLU348F, GLU348G, GLU384F, GLU384G, GLY113F, GLY113G, GLY114F, GLY114G, GLY118F, GLY118G, GLY141F, GLY141G, GLY342F, GLY342G, GLY362F, GLY362G, GLY385F, GLY385G, HIS334F, HIS334G, HIS344F, HIS344G, ILE117F, ILE117G, ILE347F, ILE347G, LEU111F, LEU111G, LEU138F, LEU138G, LEU338F, LEU338G, LEU360F, LEU376F, LYS160F, LYS160G, LYS3F, LYS3G, LYS88F, LYS88G, MET1F, MET1G, MET333F, MET333G, MET341F, MET341G, MET366F, MET366G, PHE328F, PHE328G, PHE332F, PHE332G, PRO112F, PRO112G, PRO121F, PRO121G, PRO336F, PRO336G, PRO83F, PRO83G, SER110F, SER110G, SER339F, SER339G, SER349F, SER349G, SER361F, SER361G, THR116F, THR116G, THR368F, THR368G, THR386F, THR386G, THR387F, THR89F, THR89G, TYR142F, TYR142G, TYR393F, TYR393G, TYR84F, TYR84G, VAL109F, VAL109G, VAL122F, VAL122G, VAL143F, VAL143G, VAL335F, VAL335G, VAL365F, VAL365G, VAL388F, VAL388G, VAL389F, VAL389G, VAL87F, VAL87G
• F-H: ALA134H, ARG150H, ARG246F, ARG288F, ASP148H, ASP272F, ASP283F, GLN13F, GLU177H, GLU219H, GLU318F, GLY133H, GLY149H, GLY178H, GLY247F, GLY286F, HIS285F, LYS11F, LYS152H, LYS248F, LYS287F, LYS290F, MET284F, SER146H, THR135H, VAL147H
• G-K: ALA134G, ALA62K, ARG150G, ASN78K, ASP148G, ASP51K, ASP76K, ASP85K, GLN131G, GLN59K, GLU130G, GLU177G, GLU65K, GLY133G, GLY149G, GLY61K, ILE136G, LEU86K, LYS137G, LYS152G, LYS55K, LYS63K, MET54K, PRO83K, SER58K, THR135G, VAL147G, VAL64K, VAL79K
• H-J: GLY418H, LYS204J, LYS417H, MET1H
• H-K: ASN78H, GLU139H, GLU140H, GLU216K, GLY202K, LYS144H, LYS204K, TYR142H, VAL218K, VAL225K
• I-J: ALA119I, ALA119J, ALA343I, ALA343J, ALA345I, ALA345J, ALA363I, ALA363J, ALA82J, ARG120I, ARG120J, ARG331I, ARG331J, ARG340I, ARG340J, ARG391I, ARG391J, ARG91I, ARG91J, ASN330I, ASN330J, ASN350I, ASN350J, ASP123I, ASP123J, ASP390I, ASP390J, ASP85I, ASP85J, CYS115I, CYS115J, GLN364I, GLN364J, GLU139I, GLU139J, GLU140I, GLU140J, GLU329I, GLU329J, GLU337I, GLU337J, GLU346I, GLU346J, GLU348I, GLU348J, GLU384I, GLY113I, GLY113J, GLY114I, GLY114J, GLY118I, GLY118J, GLY141I, GLY141J, GLY342I, GLY342J, GLY362I, GLY362J, GLY385I, GLY385J, HIS334I, HIS334J, HIS344I, HIS344J, ILE117I, ILE117J, ILE347I, ILE347J, LEU111I, LEU111J, LEU138I, LEU138J, LEU338I, LEU338J, LYS160I, LYS160J, LYS3I, LYS3J, LYS88I, LYS88J, MET1J, MET333I, MET333J, MET341I, MET341J, MET366I, MET366J, PHE328J, PHE332I, PHE332J, PRO112I, PRO112J, PRO121I, PRO121J, PRO336I, PRO336J, PRO83I, PRO83J, SER110I, SER110J, SER339I, SER339J, SER349I, SER349J, SER361I, SER361J, THR116I, THR116J, THR368I, THR368J, THR386I, THR386J, THR387I, THR89I, THR89J, TYR142I, TYR142J, TYR393I, TYR393J, TYR84I, TYR84J, VAL109I, VAL109J, VAL122I, VAL122J, VAL143I, VAL143J, VAL335I, VAL335J, VAL365I, VAL365J, VAL388I, VAL388J, VAL389I, VAL87I, VAL87J
• I-K: ALA345I, ALA345K, ARG295I, ARG295K, ASN293I, ASN293K, ASN350I, ASN350K, CYS354I, CYS354K, GLU325I, GLU325K, GLU346I, GLU346K, GLU348I, GLU348K, GLY319I, GLY319K, GLY321I, GLY321K, HIS355I, HIS355K, ILE323I, ILE323K, ILE347I, ILE347K, ILE353I, ILE353K, PHE322I, PHE322K, SER349I, SER349K, THR320I, THR320K, THR324I, THR324K, THR326I, THR326K, THR351I, THR351K, VAL294I, VAL294K, VAL352I, VAL352K
• I-L: ALA154I, ALA185I, ALA185L, ALA186I, ALA186L, ALA261I, ALA261L, ALA264I, ALA264L, ALA297I, ALA297L, ALA301I, ALA301L, ARG187I, ARG187L, ARG212I, ARG212L, ARG267I, ARG267L, ARG295I, ARG295L, ASN184I, ASN184L, ASN293I, ASN293L, ASN350I, ASN350L, ASP159I, ASP159L, ASP211I, ASP211L, ASP257I, ASP257L, ASP260I, ASP260L, ASP268I, ASP268L, GLN131I, GLN131L, GLU183I, GLU183L, GLU329I, GLU329L, GLY209I, GLY209L, HIS155I, HIS155L, HIS299I, HIS299L, ILE156I, ILE156L, ILE181I, ILE181L, LEU124I, LEU259I, LEU259L, LEU263I, LEU263L, LYS160I, LYS160L, LYS265I, LYS265L, MET158I, MET158L, PHE302I, PHE302L, PHE322I, PHE322L, PRO298I, PRO298L, PRO300I, PRO300L, SER349I, SER349L, THR210I, THR210L, THR258I, THR324I, THR324L, THR326I, THR326L, VAL157I, VAL157L, VAL161I, VAL161L, VAL262I, VAL262L, VAL294I, VAL294L
• J-K: ALA185J, ALA185K, ALA186J, ALA186K, ALA261J, ALA261K, ALA264J, ALA264K, ALA297J, ALA297K, ALA301J, ALA301K, ARG187J, ARG187K, ARG212J, ARG212K, ARG267J, ARG267K, ARG295J, ARG295K, ASN184J, ASN184K, ASN293J, ASN293K, ASN350J, ASN350K, ASP159J, ASP159K, ASP211J, ASP211K, ASP257J, ASP257K, ASP260J, ASP260K, ASP268J, ASP268K, GLN131J, GLN131K, GLU183J, GLU183K, GLU329J, GLU329K, GLY209J, GLY209K, HIS155J, HIS155K, HIS299J, HIS299K, ILE156J, ILE156K, ILE181J, ILE181K, LEU124K, LEU259J, LEU259K, LEU263J, LEU263K, LYS160J, LYS160K, LYS265J, LYS265K, MET158J, MET158K, PHE302J, PHE302K, PHE322J, PHE322K, PRO256J, PRO298J, PRO298K, PRO300J, PRO300K, THR210J, THR210K, THR324J, THR324K, THR326J, THR326K, VAL157J, VAL157K, VAL161J, VAL161K, VAL262J, VAL262K, VAL292J, VAL294J, VAL294K, VAL327J, VAL327K
• J-L: ALA345L, ARG295J, ARG295L, ASN293J, ASN293L, ASN350J, ASN350L, CYS354J, CYS354L, GLU325J, GLU325L, GLU346J, GLU346L, GLU348J, GLU348L, GLY319L, GLY321J, GLY321L, HIS355J, HIS355L, ILE323J, ILE323L, ILE347J, ILE347L, ILE353J, ILE353L, PHE322J, PHE322L, SER349J, SER349L, THR320J, THR320L, THR324J, THR324L, THR326J, THR326L, THR351J, THR351L, VAL294J, VAL352J, VAL352L
• K-L: ALA119K, ALA119L, ALA343K, ALA343L, ALA345K, ALA345L, ALA363K, ALA363L, ALA367K, ALA367L, ALA82K, ALA82L, ARG120K, ARG120L, ARG331K, ARG331L, ARG340K, ARG340L, ARG391K, ARG391L, ARG91K, ARG91L, ASN330K, ASN330L, ASN350K, ASN350L, ASP123K, ASP123L, ASP390K, ASP390L, ASP85K, ASP85L, CYS115K, CYS115L, GLN364K, GLN364L, GLU139K, GLU139L, GLU140K, GLU140L, GLU329K, GLU329L, GLU337K, GLU337L, GLU346K, GLU346L, GLU348K, GLU348L, GLU384K, GLU384L, GLY113K, GLY113L, GLY114K, GLY114L, GLY118K, GLY118L, GLY141K, GLY141L, GLY342K, GLY342L, GLY362K, GLY362L, GLY385K, GLY385L, HIS334K, HIS334L, HIS344K, HIS344L, HIS394K, HIS394L, ILE117K, ILE117L, ILE347K, ILE347L, LEU111K, LEU111L, LEU138K, LEU138L, LEU338K, LEU338L, LEU360K, LEU376K, LEU376L, LEU86L, LYS160K, LYS160L, LYS3K, LYS3L, LYS88K, LYS88L, MET1K, MET1L, MET333K, MET333L, MET341K, MET341L, MET366K, MET366L, PHE328K, PHE328L, PHE332K, PHE332L, PRO112K, PRO112L, PRO121K, PRO121L, PRO336K, PRO336L, PRO83K, PRO83L, SER110K, SER110L, SER339K, SER339L, SER349K, SER349L, SER361K, SER361L, THR116K, THR116L, THR368K, THR368L, THR386K, THR386L, THR387K, THR89K, THR89L, TYR142K, TYR142L, TYR393K, TYR393L, TYR84K, TYR84L, VAL109K, VAL109L, VAL122K, VAL122L, VAL143K, VAL143L, VAL335K, VAL335L, VAL365K, VAL365L, VAL388K, VAL388L, VAL389K, VAL389L, VAL87K, VAL87L