3IKU

structural model of parm filament in closed state from cryo- em

• Total interactions analyzed: 66
• Total true interactions: 21
• Strongest Interaction:
  • Chains: J-K
  • Int. Res.: 69
  • Norm. En. per Res.: 0.5627
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-21.4475	27.3663	33.2082	39.127	69	21	0	2981	0	23	20
A-C	-244.2954	-32.2588	2799.74	2523.1858	89	558	2	12187	0	27	24
B-C	-21.489	27.3561	33.3923	39.2594	69	21	0	2981	0	23	20
B-D	-243.9048	-32.2626	2801.62	2525.4526	89	558	2	12187	0	27	24
C-D	-21.5091	27.3576	33.2764	39.1249	69	21	0	2981	0	23	20
C-E	-244.0878	-32.2633	2798.97	2522.6188	89	557	2	12187	0	27	24
D-E	-21.5009	27.3589	33.1806	39.0386	69	21	0	2981	0	23	20
D-F	-243.9486	-32.265	2800.67	2524.4563	89	559	2	12187	0	27	24
E-F	-21.5007	27.3566	33.2842	39.1401	69	21	0	2981	0	23	20
E-G	-244.0769	-32.2685	2801.92	2525.5746	89	558	2	12188	0	27	24
F-G	-21.5129	27.3562	33.3998	39.2431	69	21	0	2981	0	23	20
F-H	-244.4962	-32.2666	2800.55	2523.7871	89	557	2	12188	0	27	24
G-H	-21.4543	27.3557	33.1365	39.0378	69	21	0	2981	0	23	20
G-I	-244.4469	-32.2655	2801.44	2524.7276	89	557	2	12187	0	27	24
H-I	-21.4757	27.3593	33.3866	39.2702	69	21	0	2982	0	23	20
H-J	-243.4073	-32.2635	2801.2	2525.5292	89	556	2	12186	0	27	24
I-J	-21.4855	27.3543	33.0418	38.9106	69	21	0	2981	0	23	20
I-K	-243.7454	-32.262	2800.92	2524.9126	89	557	2	12187	0	27	24
J-K	-21.4591	27.3582	32.9304	38.8295	69	21	0	2981	0	23	20
J-L	-243.6567	-32.2606	2800.45	2524.5326	89	558	2	12188	0	27	24
K-L	-21.5337	27.3493	33.3475	39.1631	69	21	0	2982	0	23	20

Interface residues

• A-B: ALA205B, ALA255A, ALA71B, ARG110A, ARG121B, ARG214A, ARG214B, ARG257A, ARG262A, ARG34B, ASN115A, ASN265A, ASN268A, ASN51B, ASN69B, ASP109A, ASP194A, ASP208B, ASP63B, ASP76B, GLN261A, GLN54B, GLU106A, GLU254A, GLU260A, GLU269A, GLU35B, GLU53B, GLY193A, GLY52B, ILE60B, ILE70B, LEU176A, LEU197A, LEU197B, LEU201A, LEU201B, LEU259A, LEU264A, LEU50B, LYS128B, LYS190A, LYS258A, LYS33B, PHE270A, PHE32B, PHE40B, SER195A, SER196A, SER196B, SER200B, SER204A, SER204B, SER61B, SER75B, THR105A, THR174B, THR215B, THR266A, THR49B, THR68B, TRP36B, TRP72B, TYR108A, TYR192A, TYR55B, VAL263A, VAL38B, VAL77B
• A-C: ALA213C, ALA37C, ARG110A, ARG238C, ARG297A, ARG300A, ARG34C, ASN111A, ASN112A, ASN115A, ASN118A, ASN133C, ASN240C, ASN47C, ASP109A, ASP161A, ASP164A, ASP224C, ASP241C, ASP42C, ASP58C, GLN113A, GLN180A, GLN237C, GLN54C, GLU106A, GLU148A, GLU162A, GLU242C, GLU35C, GLY187A, GLY272A, GLY41C, HIS228C, HIS275A, ILE119A, ILE150A, ILE188A, ILE191A, ILE239C, ILE296A, LEU102A, LEU104A, LEU160A, LEU163A, LEU185A, LEU210C, LEU212C, LEU221C, LEU235C, LYS190A, LYS236C, LYS244C, LYS33C, LYS43C, LYS44C, MET146A, MET182A, PHE40C, PHE46C, PHE57C, PRO103A, PRO114A, PRO147A, PRO151A, PRO59C, SER149A, SER165A, SER179A, SER186A, SER189A, SER211C, SER271A, SER39C, SER56C, THR105A, THR274A, TRP36C, TYR107A, TYR108A, TYR220C, TYR234C, TYR273A, TYR48C, TYR55C, VAL145A, VAL181A, VAL38C, VAL45C
• B-C: ALA205C, ALA255B, ALA71C, ARG110B, ARG121C, ARG214B, ARG214C, ARG257B, ARG262B, ARG34C, ASN115B, ASN265B, ASN268B, ASN51C, ASN69C, ASP109B, ASP194B, ASP208C, ASP63C, ASP76C, GLN261B, GLN54C, GLU106B, GLU254B, GLU260B, GLU269B, GLU35C, GLU53C, GLY193B, GLY52C, ILE60C, ILE70C, LEU176B, LEU197B, LEU197C, LEU201B, LEU201C, LEU259B, LEU264B, LEU50C, LYS128C, LYS190B, LYS258B, LYS33C, PHE270B, PHE32C, PHE40C, SER195B, SER196B, SER196C, SER200C, SER204B, SER204C, SER61C, SER75C, THR105B, THR174C, THR215C, THR266B, THR49C, THR68C, TRP36C, TRP72C, TYR108B, TYR192B, TYR55C, VAL263B, VAL38C, VAL77C
• B-D: ALA213D, ALA37D, ARG110B, ARG238D, ARG297B, ARG300B, ARG34D, ASN111B, ASN112B, ASN115B, ASN118B, ASN133D, ASN240D, ASN47D, ASP109B, ASP161B, ASP164B, ASP224D, ASP241D, ASP42D, ASP58D, GLN113B, GLN180B, GLN237D, GLN54D, GLU106B, GLU148B, GLU162B, GLU242D, GLU35D, GLY187B, GLY272B, GLY41D, HIS228D, HIS275B, ILE119B, ILE150B, ILE188B, ILE191B, ILE239D, ILE296B, LEU102B, LEU104B, LEU160B, LEU163B, LEU185B, LEU210D, LEU212D, LEU221D, LEU235D, LYS190B, LYS236D, LYS244D, LYS33D, LYS43D, LYS44D, MET146B, MET182B, PHE40D, PHE46D, PHE57D, PRO103B, PRO114B, PRO147B, PRO151B, PRO59D, SER149B, SER165B, SER179B, SER186B, SER189B, SER211D, SER271B, SER39D, SER56D, THR105B, THR274B, TRP36D, TYR107B, TYR108B, TYR220D, TYR234D, TYR273B, TYR48D, TYR55D, VAL145B, VAL181B, VAL38D, VAL45D
• C-D: ALA205D, ALA255C, ALA71D, ARG110C, ARG121D, ARG214C, ARG214D, ARG257C, ARG262C, ARG34D, ASN115C, ASN265C, ASN268C, ASN51D, ASN69D, ASP109C, ASP194C, ASP208D, ASP63D, ASP76D, GLN261C, GLN54D, GLU106C, GLU254C, GLU260C, GLU269C, GLU35D, GLU53D, GLY193C, GLY52D, ILE60D, ILE70D, LEU176C, LEU197C, LEU197D, LEU201C, LEU201D, LEU259C, LEU264C, LEU50D, LYS128D, LYS190C, LYS258C, LYS33D, PHE270C, PHE32D, PHE40D, SER195C, SER196C, SER196D, SER200D, SER204C, SER204D, SER61D, SER75D, THR105C, THR174D, THR215D, THR266C, THR49D, THR68D, TRP36D, TRP72D, TYR108C, TYR192C, TYR55D, VAL263C, VAL38D, VAL77D
• C-E: ALA213E, ALA37E, ARG110C, ARG238E, ARG297C, ARG300C, ARG34E, ASN111C, ASN112C, ASN115C, ASN118C, ASN133E, ASN240E, ASN47E, ASP109C, ASP161C, ASP164C, ASP224E, ASP241E, ASP42E, ASP58E, GLN113C, GLN180C, GLN237E, GLN54E, GLU106C, GLU148C, GLU162C, GLU242E, GLU35E, GLY187C, GLY272C, GLY41E, HIS228E, HIS275C, ILE119C, ILE150C, ILE188C, ILE191C, ILE239E, ILE296C, LEU102C, LEU104C, LEU160C, LEU163C, LEU185C, LEU210E, LEU212E, LEU221E, LEU235E, LYS190C, LYS236E, LYS244E, LYS33E, LYS43E, LYS44E, MET146C, MET182C, PHE40E, PHE46E, PHE57E, PRO103C, PRO114C, PRO147C, PRO151C, PRO59E, SER149C, SER165C, SER179C, SER186C, SER189C, SER211E, SER271C, SER39E, SER56E, THR105C, THR274C, TRP36E, TYR107C, TYR108C, TYR220E, TYR234E, TYR273C, TYR48E, TYR55E, VAL145C, VAL181C, VAL38E, VAL45E
• D-E: ALA205E, ALA255D, ALA71E, ARG110D, ARG121E, ARG214D, ARG214E, ARG257D, ARG262D, ARG34E, ASN115D, ASN265D, ASN268D, ASN51E, ASN69E, ASP109D, ASP194D, ASP208E, ASP63E, ASP76E, GLN261D, GLN54E, GLU106D, GLU254D, GLU260D, GLU269D, GLU35E, GLU53E, GLY193D, GLY52E, ILE60E, ILE70E, LEU176D, LEU197D, LEU197E, LEU201D, LEU201E, LEU259D, LEU264D, LEU50E, LYS128E, LYS190D, LYS258D, LYS33E, PHE270D, PHE32E, PHE40E, SER195D, SER196D, SER196E, SER200E, SER204D, SER204E, SER61E, SER75E, THR105D, THR174E, THR215E, THR266D, THR49E, THR68E, TRP36E, TRP72E, TYR108D, TYR192D, TYR55E, VAL263D, VAL38E, VAL77E
• D-F: ALA213F, ALA37F, ARG110D, ARG238F, ARG297D, ARG300D, ARG34F, ASN111D, ASN112D, ASN115D, ASN118D, ASN133F, ASN240F, ASN47F, ASP109D, ASP161D, ASP164D, ASP224F, ASP241F, ASP42F, ASP58F, GLN113D, GLN180D, GLN237F, GLN54F, GLU106D, GLU148D, GLU162D, GLU242F, GLU35F, GLY187D, GLY272D, GLY41F, HIS228F, HIS275D, ILE119D, ILE150D, ILE188D, ILE191D, ILE239F, ILE296D, LEU102D, LEU104D, LEU160D, LEU163D, LEU185D, LEU210F, LEU212F, LEU221F, LEU235F, LYS190D, LYS236F, LYS244F, LYS33F, LYS43F, LYS44F, MET146D, MET182D, PHE40F, PHE46F, PHE57F, PRO103D, PRO114D, PRO147D, PRO151D, PRO59F, SER149D, SER165D, SER179D, SER186D, SER189D, SER211F, SER271D, SER39F, SER56F, THR105D, THR274D, TRP36F, TYR107D, TYR108D, TYR220F, TYR234F, TYR273D, TYR48F, TYR55F, VAL145D, VAL181D, VAL38F, VAL45F
• E-F: ALA205F, ALA255E, ALA71F, ARG110E, ARG121F, ARG214E, ARG214F, ARG257E, ARG262E, ARG34F, ASN115E, ASN265E, ASN268E, ASN51F, ASN69F, ASP109E, ASP194E, ASP208F, ASP63F, ASP76F, GLN261E, GLN54F, GLU106E, GLU254E, GLU260E, GLU269E, GLU35F, GLU53F, GLY193E, GLY52F, ILE60F, ILE70F, LEU176E, LEU197E, LEU197F, LEU201E, LEU201F, LEU259E, LEU264E, LEU50F, LYS128F, LYS190E, LYS258E, LYS33F, PHE270E, PHE32F, PHE40F, SER195E, SER196E, SER196F, SER200F, SER204E, SER204F, SER61F, SER75F, THR105E, THR174F, THR215F, THR266E, THR49F, THR68F, TRP36F, TRP72F, TYR108E, TYR192E, TYR55F, VAL263E, VAL38F, VAL77F
• E-G: ALA213G, ALA37G, ARG110E, ARG238G, ARG297E, ARG300E, ARG34G, ASN111E, ASN112E, ASN115E, ASN118E, ASN133G, ASN240G, ASN47G, ASP109E, ASP161E, ASP164E, ASP224G, ASP241G, ASP42G, ASP58G, GLN113E, GLN180E, GLN237G, GLN54G, GLU106E, GLU148E, GLU162E, GLU242G, GLU35G, GLY187E, GLY272E, GLY41G, HIS228G, HIS275E, ILE119E, ILE150E, ILE188E, ILE191E, ILE239G, ILE296E, LEU102E, LEU104E, LEU160E, LEU163E, LEU185E, LEU210G, LEU212G, LEU221G, LEU235G, LYS190E, LYS236G, LYS244G, LYS33G, LYS43G, LYS44G, MET146E, MET182E, PHE40G, PHE46G, PHE57G, PRO103E, PRO114E, PRO147E, PRO151E, PRO59G, SER149E, SER165E, SER179E, SER186E, SER189E, SER211G, SER271E, SER39G, SER56G, THR105E, THR274E, TRP36G, TYR107E, TYR108E, TYR220G, TYR234G, TYR273E, TYR48G, TYR55G, VAL145E, VAL181E, VAL38G, VAL45G
• F-G: ALA205G, ALA255F, ALA71G, ARG110F, ARG121G, ARG214F, ARG214G, ARG257F, ARG262F, ARG34G, ASN115F, ASN265F, ASN268F, ASN51G, ASN69G, ASP109F, ASP194F, ASP208G, ASP63G, ASP76G, GLN261F, GLN54G, GLU106F, GLU254F, GLU260F, GLU269F, GLU35G, GLU53G, GLY193F, GLY52G, ILE60G, ILE70G, LEU176F, LEU197F, LEU197G, LEU201F, LEU201G, LEU259F, LEU264F, LEU50G, LYS128G, LYS190F, LYS258F, LYS33G, PHE270F, PHE32G, PHE40G, SER195F, SER196F, SER196G, SER200G, SER204F, SER204G, SER61G, SER75G, THR105F, THR174G, THR215G, THR266F, THR49G, THR68G, TRP36G, TRP72G, TYR108F, TYR192F, TYR55G, VAL263F, VAL38G, VAL77G
• F-H: ALA213H, ALA37H, ARG110F, ARG238H, ARG297F, ARG300F, ARG34H, ASN111F, ASN112F, ASN115F, ASN118F, ASN133H, ASN240H, ASN47H, ASP109F, ASP161F, ASP164F, ASP224H, ASP241H, ASP42H, ASP58H, GLN113F, GLN180F, GLN237H, GLN54H, GLU106F, GLU148F, GLU162F, GLU242H, GLU35H, GLY187F, GLY272F, GLY41H, HIS228H, HIS275F, ILE119F, ILE150F, ILE188F, ILE191F, ILE239H, ILE296F, LEU102F, LEU104F, LEU160F, LEU163F, LEU185F, LEU210H, LEU212H, LEU221H, LEU235H, LYS190F, LYS236H, LYS244H, LYS33H, LYS43H, LYS44H, MET146F, MET182F, PHE40H, PHE46H, PHE57H, PRO103F, PRO114F, PRO147F, PRO151F, PRO59H, SER149F, SER165F, SER179F, SER186F, SER189F, SER211H, SER271F, SER39H, SER56H, THR105F, THR274F, TRP36H, TYR107F, TYR108F, TYR220H, TYR234H, TYR273F, TYR48H, TYR55H, VAL145F, VAL181F, VAL38H, VAL45H
• G-H: ALA205H, ALA255G, ALA71H, ARG110G, ARG121H, ARG214G, ARG214H, ARG257G, ARG262G, ARG34H, ASN115G, ASN265G, ASN268G, ASN51H, ASN69H, ASP109G, ASP194G, ASP208H, ASP63H, ASP76H, GLN261G, GLN54H, GLU106G, GLU254G, GLU260G, GLU269G, GLU35H, GLU53H, GLY193G, GLY52H, ILE60H, ILE70H, LEU176G, LEU197G, LEU197H, LEU201G, LEU201H, LEU259G, LEU264G, LEU50H, LYS128H, LYS190G, LYS258G, LYS33H, PHE270G, PHE32H, PHE40H, SER195G, SER196G, SER196H, SER200H, SER204G, SER204H, SER61H, SER75H, THR105G, THR174H, THR215H, THR266G, THR49H, THR68H, TRP36H, TRP72H, TYR108G, TYR192G, TYR55H, VAL263G, VAL38H, VAL77H
• G-I: ALA213I, ALA37I, ARG110G, ARG238I, ARG297G, ARG300G, ARG34I, ASN111G, ASN112G, ASN115G, ASN118G, ASN133I, ASN240I, ASN47I, ASP109G, ASP161G, ASP164G, ASP224I, ASP241I, ASP42I, ASP58I, GLN113G, GLN180G, GLN237I, GLN54I, GLU106G, GLU148G, GLU162G, GLU242I, GLU35I, GLY187G, GLY272G, GLY41I, HIS228I, HIS275G, ILE119G, ILE150G, ILE188G, ILE191G, ILE239I, ILE296G, LEU102G, LEU104G, LEU160G, LEU163G, LEU185G, LEU210I, LEU212I, LEU221I, LEU235I, LYS190G, LYS236I, LYS244I, LYS33I, LYS43I, LYS44I, MET146G, MET182G, PHE40I, PHE46I, PHE57I, PRO103G, PRO114G, PRO147G, PRO151G, PRO59I, SER149G, SER165G, SER179G, SER186G, SER189G, SER211I, SER271G, SER39I, SER56I, THR105G, THR274G, TRP36I, TYR107G, TYR108G, TYR220I, TYR234I, TYR273G, TYR48I, TYR55I, VAL145G, VAL181G, VAL38I, VAL45I
• H-I: ALA205I, ALA255H, ALA71I, ARG110H, ARG121I, ARG214H, ARG214I, ARG257H, ARG262H, ARG34I, ASN115H, ASN265H, ASN268H, ASN51I, ASN69I, ASP109H, ASP194H, ASP208I, ASP63I, ASP76I, GLN261H, GLN54I, GLU106H, GLU254H, GLU260H, GLU269H, GLU35I, GLU53I, GLY193H, GLY52I, ILE60I, ILE70I, LEU176H, LEU197H, LEU197I, LEU201H, LEU201I, LEU259H, LEU264H, LEU50I, LYS128I, LYS190H, LYS258H, LYS33I, PHE270H, PHE32I, PHE40I, SER195H, SER196H, SER196I, SER200I, SER204H, SER204I, SER61I, SER75I, THR105H, THR174I, THR215I, THR266H, THR49I, THR68I, TRP36I, TRP72I, TYR108H, TYR192H, TYR55I, VAL263H, VAL38I, VAL77I
• H-J: ALA213J, ALA37J, ARG110H, ARG238J, ARG297H, ARG300H, ARG34J, ASN111H, ASN112H, ASN115H, ASN118H, ASN133J, ASN240J, ASN47J, ASP109H, ASP161H, ASP164H, ASP224J, ASP241J, ASP42J, ASP58J, GLN113H, GLN180H, GLN237J, GLN54J, GLU106H, GLU148H, GLU162H, GLU242J, GLU35J, GLY187H, GLY272H, GLY41J, HIS228J, HIS275H, ILE119H, ILE150H, ILE188H, ILE191H, ILE239J, ILE296H, LEU102H, LEU104H, LEU160H, LEU163H, LEU185H, LEU210J, LEU212J, LEU221J, LEU235J, LYS190H, LYS236J, LYS244J, LYS33J, LYS43J, LYS44J, MET146H, MET182H, PHE40J, PHE46J, PHE57J, PRO103H, PRO114H, PRO147H, PRO151H, PRO59J, SER149H, SER165H, SER179H, SER186H, SER189H, SER211J, SER271H, SER39J, SER56J, THR105H, THR274H, TRP36J, TYR107H, TYR108H, TYR220J, TYR234J, TYR273H, TYR48J, TYR55J, VAL145H, VAL181H, VAL38J, VAL45J
• I-J: ALA205J, ALA255I, ALA71J, ARG110I, ARG121J, ARG214I, ARG214J, ARG257I, ARG262I, ARG34J, ASN115I, ASN265I, ASN268I, ASN51J, ASN69J, ASP109I, ASP194I, ASP208J, ASP63J, ASP76J, GLN261I, GLN54J, GLU106I, GLU254I, GLU260I, GLU269I, GLU35J, GLU53J, GLY193I, GLY52J, ILE60J, ILE70J, LEU176I, LEU197I, LEU197J, LEU201I, LEU201J, LEU259I, LEU264I, LEU50J, LYS128J, LYS190I, LYS258I, LYS33J, PHE270I, PHE32J, PHE40J, SER195I, SER196I, SER196J, SER200J, SER204I, SER204J, SER61J, SER75J, THR105I, THR174J, THR215J, THR266I, THR49J, THR68J, TRP36J, TRP72J, TYR108I, TYR192I, TYR55J, VAL263I, VAL38J, VAL77J
• I-K: ALA213K, ALA37K, ARG110I, ARG238K, ARG297I, ARG300I, ARG34K, ASN111I, ASN112I, ASN115I, ASN118I, ASN133K, ASN240K, ASN47K, ASP109I, ASP161I, ASP164I, ASP224K, ASP241K, ASP42K, ASP58K, GLN113I, GLN180I, GLN237K, GLN54K, GLU106I, GLU148I, GLU162I, GLU242K, GLU35K, GLY187I, GLY272I, GLY41K, HIS228K, HIS275I, ILE119I, ILE150I, ILE188I, ILE191I, ILE239K, ILE296I, LEU102I, LEU104I, LEU160I, LEU163I, LEU185I, LEU210K, LEU212K, LEU221K, LEU235K, LYS190I, LYS236K, LYS244K, LYS33K, LYS43K, LYS44K, MET146I, MET182I, PHE40K, PHE46K, PHE57K, PRO103I, PRO114I, PRO147I, PRO151I, PRO59K, SER149I, SER165I, SER179I, SER186I, SER189I, SER211K, SER271I, SER39K, SER56K, THR105I, THR274I, TRP36K, TYR107I, TYR108I, TYR220K, TYR234K, TYR273I, TYR48K, TYR55K, VAL145I, VAL181I, VAL38K, VAL45K
• J-K: ALA205K, ALA255J, ALA71K, ARG110J, ARG121K, ARG214J, ARG214K, ARG257J, ARG262J, ARG34K, ASN115J, ASN265J, ASN268J, ASN51K, ASN69K, ASP109J, ASP194J, ASP208K, ASP63K, ASP76K, GLN261J, GLN54K, GLU106J, GLU254J, GLU260J, GLU269J, GLU35K, GLU53K, GLY193J, GLY52K, ILE60K, ILE70K, LEU176J, LEU197J, LEU197K, LEU201J, LEU201K, LEU259J, LEU264J, LEU50K, LYS128K, LYS190J, LYS258J, LYS33K, PHE270J, PHE32K, PHE40K, SER195J, SER196J, SER196K, SER200K, SER204J, SER204K, SER61K, SER75K, THR105J, THR174K, THR215K, THR266J, THR49K, THR68K, TRP36K, TRP72K, TYR108J, TYR192J, TYR55K, VAL263J, VAL38K, VAL77K
• J-L: ALA213L, ALA37L, ARG110J, ARG238L, ARG297J, ARG300J, ARG34L, ASN111J, ASN112J, ASN115J, ASN118J, ASN133L, ASN240L, ASN47L, ASP109J, ASP161J, ASP164J, ASP224L, ASP241L, ASP42L, ASP58L, GLN113J, GLN180J, GLN237L, GLN54L, GLU106J, GLU148J, GLU162J, GLU242L, GLU35L, GLY187J, GLY272J, GLY41L, HIS228L, HIS275J, ILE119J, ILE150J, ILE188J, ILE191J, ILE239L, ILE296J, LEU102J, LEU104J, LEU160J, LEU163J, LEU185J, LEU210L, LEU212L, LEU221L, LEU235L, LYS190J, LYS236L, LYS244L, LYS33L, LYS43L, LYS44L, MET146J, MET182J, PHE40L, PHE46L, PHE57L, PRO103J, PRO114J, PRO147J, PRO151J, PRO59L, SER149J, SER165J, SER179J, SER186J, SER189J, SER211L, SER271J, SER39L, SER56L, THR105J, THR274J, TRP36L, TYR107J, TYR108J, TYR220L, TYR234L, TYR273J, TYR48L, TYR55L, VAL145J, VAL181J, VAL38L, VAL45L
• K-L: ALA205L, ALA255K, ALA71L, ARG110K, ARG121L, ARG214K, ARG214L, ARG257K, ARG262K, ARG34L, ASN115K, ASN265K, ASN268K, ASN51L, ASN69L, ASP109K, ASP194K, ASP208L, ASP63L, ASP76L, GLN261K, GLN54L, GLU106K, GLU254K, GLU260K, GLU269K, GLU35L, GLU53L, GLY193K, GLY52L, ILE60L, ILE70L, LEU176K, LEU197K, LEU197L, LEU201K, LEU201L, LEU259K, LEU264K, LEU50L, LYS128L, LYS190K, LYS258K, LYS33L, PHE270K, PHE32L, PHE40L, SER195K, SER196K, SER196L, SER200L, SER204K, SER204L, SER61L, SER75L, THR105K, THR174L, THR215L, THR266K, THR49L, THR68L, TRP36L, TRP72L, TYR108K, TYR192K, TYR55L, VAL263K, VAL38L, VAL77L