3IKA

crystal structure of egfr 696-1022 t790m mutant covalently binding to wz4002

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 102
  • Norm. En. per Res.: -2.4657
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-17.1092	19.0616	-253.454	-251.5016	102	22	8	11494	0	27	28

Interface residues

• A-B: ALA698A, ALA702A, ALA750A, ALA755A, ALA763A, ALA767A, ALA864A, ALA955B, ARG705A, ARG776A, ARG831A, ARG932B, ARG958B, ARG977B, ASN700A, ASN756A, ASP761A, ASP942B, ASP954B, ASP956B, ASP974B, CB7.84928-15.79438, CB9.4997732.72917, CYS781A, CYS939B, CYS950B, GLN701A, GLN787A, GLN935B, GLN976B, GLU697A, GLU697A9, GLU709A, GLU711A, GLU734A, GLU749A, GLU758A, GLU762A, GLU928B, GLU931B, GLU963B, GLU967B, GLY696A, GLY930B, ILE706A, ILE759A, ILE780A, ILE926B, ILE938B, ILE941B, ILE946B, ILE953B, ILE981B, LEU703A, LEU704A, LEU707A, LEU760A, LEU777A, LEU782A, LEU861A, LEU883B, LEU927B, LEU933B, LEU979B, LYS708A, LYS754A, LYS757A, LYS929B, LYS949B, MET766A, MET945B, MET947B, MET952B, PHE712A, PRO699A, PRO753A, PRO934B, PRO936B, PRO937B, PRO959B, PRO975B, SER752A, SER768A, SER784A, SER925B, SER957B, THR710A, THR751A, THR783A, THR785A, THR940B, TRP898B, TRP951B, TYR764A, TYR944B, TYR978B, VAL765A, VAL769A, VAL786A, VAL943B, VAL948B, VAL980B