3II0

crystal structure of human glutamate oxaloacetate transaminase 1 (got1)

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 205
  • Norm. En. per Res.: -4.781
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.0035	-0.0035	7	0	0	6	0	2	5
A-C	-9.4105	3.5324	-30.9758	-36.8539	37	0	0	1761	1	21	20
A-D	-118.9516	-161.1789	-673.463	-953.5935	207	31	15	25950	13	32	47
B-C	-126.9573	-162.3048	-690.837	-980.0991	205	37	16	26186	14	32	47
B-D	0.0	4.7904	-9.2754	-4.485	34	1	0	786	0	17	14
C-D	-5.6038	0.0	-3.7805	-9.3843	7	1	0	177	0	0	0

Interface residues

• A-B: GLN59A, GLN59B, LYS55A, LYS55B, LYS56B, PRO52A, PRO52B
• A-C: ARG330A, ARG341A, ASN313C, ASN397A, ASN63C, ASN65C, ASP399A, ASP44A, ASP45A, ASP64C, CYS46A, GLN59C, GLU315C, GLU337A, HIS47A, ILE61C, LEU316C, LEU398A, LEU67C, LYS396A, LYS55A, LYS56C, LYS60C, PRO314C, PRO48A, PRO52A, SER309C, SER312C, SER66C, THR326A, THR333A, THR394A, THR395A, THR43A, TRP49A, VAL50A, VAL57C
• A-D: ALA112A, ALA112D, ALA117A, ALA117D, ALA146A, ALA146D, ALA150A, ALA150D, ALA151A, ALA151D, ALA225A, ALA225D, ALA23A, ALA23D, ALA301A, ALA301D, ALA304A, ALA304D, ALA40A, ALA40D, ALA62A, ALA62D, ARG114A, ARG114D, ARG122D, ARG267A, ARG267D, ARG26A, ARG26D, ARG293A, ARG293D, ARG305A, ARG305D, ARG387A, ARG387D, ARG42A, ARG42D, ASN143A, ASN143D, ASN145A, ASN145D, ASN195A, ASN195D, ASN265A, ASN265D, ASN298A, ASN298D, ASN63A, ASN63D, ASN65A, ASN65D, ASN68A, ASN68D, ASP118A, ASP118D, ASP64A, ASP64D, GLN105A, GLN105D, GLN14D, GLN287A, GLN287D, GLN302A, GLN302D, GLN59A, GLN59D, GLU142A, GLU142D, GLU266A, GLU266D, GLU289A, GLU289D, GLU58A, GLU58D, GLU70A, GLU70D, GLY108A, GLY108D, GLY109A, GLY109D, GLY111A, GLY111D, GLY152A, GLY262A, GLY262D, GLY303A, GLY303D, GLY39A, GLY39D, GLY76D, HIS144A, HIS144D, HIS47A, HIS47D, HIS69A, HIS69D, ILE115A, ILE115D, ILE291A, ILE291D, ILE294A, ILE294D, ILE306A, ILE306D, ILE61A, ILE61D, ILE74A, ILE74D, LEU107A, LEU107D, LEU113A, LEU113D, LEU17A, LEU17D, LEU263A, LEU263D, LEU383D, LEU51A, LEU51D, LEU67A, LEU67D, LEU72A, LEU72D, LEU75A, LEU75D, LEU77A, LEU77D, LYS20A, LYS20D, LYS259A, LYS259D, LYS290A, LYS290D, LYS55A, LYS55D, LYS60A, LYS60D, MET13D, MET288A, MET288D, MET360A, PHE148A, PHE148D, PHE19A, PHE19D, PHE261A, PHE261D, PRO15A, PRO15D, PRO299A, PRO299D, PRO300A, PRO300D, PRO48A, PRO48D, PRO73A, PRO73D, SER106A, SER106D, SER149A, SER149D, SER256A, SER256D, SER258A, SER258D, SER286A, SER286D, SER297A, SER297D, SER66A, SER66D, THR110A, THR110D, THR22A, THR22D, THR295A, THR295D, TRP141A, TRP141D, TRP296A, TRP296D, TRP49A, TRP49D, TYR226A, TYR226D, TYR264A, TYR264D, TYR41A, TYR41D, TYR71A, TYR71D, VAL147A, VAL147D, VAL16A, VAL16D, VAL18A, VAL18D, VAL268A, VAL268D, VAL292A, VAL292D, VAL38A, VAL38D, VAL50A, VAL50D, VAL54A, VAL54D
• B-C: ALA112B, ALA112C, ALA117B, ALA146B, ALA146C, ALA150B, ALA150C, ALA151B, ALA151C, ALA225B, ALA225C, ALA23B, ALA23C, ALA301B, ALA301C, ALA304B, ALA304C, ALA40B, ALA40C, ALA62B, ALA62C, ARG114B, ARG114C, ARG122C, ARG267B, ARG267C, ARG26B, ARG26C, ARG293B, ARG293C, ARG305B, ARG305C, ARG387B, ARG387C, ARG42B, ARG42C, ASN143B, ASN143C, ASN145B, ASN145C, ASN195B, ASN195C, ASN265B, ASN265C, ASN298B, ASN298C, ASN63B, ASN63C, ASN65B, ASN65C, ASN68B, ASN68C, ASP118B, ASP118C, ASP64B, ASP64C, GLN105B, GLN105C, GLN14C, GLN287B, GLN287C, GLN302B, GLN302C, GLN59B, GLN59C, GLU142B, GLU142C, GLU266B, GLU266C, GLU289B, GLU289C, GLU58B, GLU58C, GLU70B, GLU70C, GLY108B, GLY108C, GLY109B, GLY109C, GLY111B, GLY111C, GLY152B, GLY262B, GLY262C, GLY303B, GLY303C, GLY39B, GLY39C, HIS144B, HIS144C, HIS47B, HIS47C, HIS69B, HIS69C, ILE115B, ILE115C, ILE291B, ILE291C, ILE294B, ILE294C, ILE306B, ILE306C, ILE61B, ILE61C, ILE74B, ILE74C, LEU107B, LEU107C, LEU113B, LEU113C, LEU17B, LEU17C, LEU263B, LEU263C, LEU383B, LEU383C, LEU51B, LEU51C, LEU67B, LEU67C, LEU72B, LEU72C, LEU75B, LEU75C, LEU77B, LEU77C, LYS20B, LYS20C, LYS259B, LYS259C, LYS290B, LYS290C, LYS55B, LYS55C, LYS60B, LYS60C, MET13C, MET288B, MET288C, PHE148B, PHE148C, PHE19B, PHE19C, PHE261B, PHE261C, PRO15B, PRO15C, PRO299B, PRO299C, PRO300B, PRO300C, PRO48B, PRO48C, PRO73B, PRO73C, SER106B, SER106C, SER149B, SER149C, SER256B, SER256C, SER258B, SER258C, SER286B, SER286C, SER297B, SER297C, SER66B, SER66C, THR110B, THR110C, THR22B, THR22C, THR295B, THR295C, TRP141B, TRP141C, TRP296B, TRP296C, TRP49B, TRP49C, TYR226B, TYR226C, TYR264B, TYR264C, TYR41B, TYR41C, TYR71B, TYR71C, VAL147B, VAL147C, VAL16B, VAL16C, VAL18B, VAL18C, VAL268B, VAL268C, VAL292B, VAL292C, VAL38B, VAL38C, VAL50B, VAL50C, VAL54B, VAL54C
• B-D: ARG330B, ARG341B, ASN313D, ASN323B, ASN63D, ASN65D, ASP399B, ASP44B, ASP45B, ASP64D, GLU315D, GLU337B, GLU79D, HIS47B, LEU316D, LEU398B, LEU67D, LYS396B, LYS55B, LYS60D, MET334B, PRO314D, PRO48B, PRO52B, SER309D, SER312D, SER66D, THR326B, THR333B, THR394B, THR395B, THR43B, TRP49B, VAL50B
• C-D: ASN65C, ASN65D, ASN68D, ASP64D, LEU67D, SER66C, SER66D