3IFS

2.0 angstrom resolution crystal structure of glucose-6-phosphate isomerase (pgi) from bacillus anthracis.

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 439
  • Norm. En. per Res.: -4.9006
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-211.4484	-371.9365	-1567.96	-2151.3449	439	41	43	60998	30	172	135
A-C	0.0	0.0	-22.0001	-22.0001	25	0	0	908	0	14	15
A-D	-46.3727	-37.6114	-201.746	-285.7301	103	12	5	8389	6	38	33
B-C	-68.4747	-38.2177	-204.484	-311.1764	100	11	5	8316	6	37	33
B-D	0.0	0.0	-24.3224	-24.3224	24	0	0	973	0	14	15
B-E	0.0	0.0	-0.0133	-0.0133	3	0	0	2	0	0	3
B-F	0.0	0.0	-0.0702	-0.0702	9	0	0	35	0	8	7
C-D	-211.8218	-352.0963	-1569.36	-2133.2782	437	37	42	60297	30	173	134
C-E	0.0	2.2129	-0.0052	2.2077	4	0	0	4	0	3	4
C-F	-25.5493	35.2338	-39.2636	-29.5791	26	3	0	1057	2	16	18
D-F	-9.0732	21.7726	-31.6012	-18.9018	27	1	0	1530	4	29	32
E-F	-196.4866	-339.0063	-1558.6	-2094.0929	437	35	42	60472	30	173	132

Interface residues

• A-B: ALA12A, ALA153A, ALA153B, ALA155A, ALA155B, ALA186A, ALA186B, ALA191A, ALA191B, ALA277A, ALA277B, ALA282A, ALA282B, ALA305A, ALA305B, ALA355A, ALA355B, ALA366A, ALA366B, ALA373A, ALA373B, ALA424A, ALA424B, ALA431A, ALA431B, ARG109A, ARG109B, ARG157A, ARG157B, ARG160A, ARG160B, ARG208A, ARG208B, ARG258A, ARG258B, ARG322A, ARG322B, ARG323A, ARG323B, ARG448A, ARG448B, ARG90A, ARG90B, ASN102A, ASN102B, ASN120A, ASN120B, ASN193A, ASN193B, ASN263A, ASN306A, ASN306B, ASN346A, ASN346B, ASN352A, ASN352B, ASN363A, ASN363B, ASN415A, ASN415B, ASN428A, ASN428B, ASN97A, ASN97B, ASP128A, ASP128B, ASP131A, ASP131B, ASP192A, ASP192B, ASP296A, ASP296B, ASP310A, ASP310B, ASP324A, ASP324B, ASP347A, ASP347B, ASP349A, ASP349B, ASP360A, ASP360B, ASP376A, ASP376B, ASP418A, ASP418B, ASP8A, GLN108A, GLN108B, GLN113A, GLN113B, GLN119A, GLN119B, GLN279A, GLN279B, GLN287A, GLN287B, GLN297A, GLN297B, GLN316A, GLN316B, GLN319A, GLN319B, GLN419A, GLN419B, GLU134A, GLU134B, GLU151A, GLU151B, GLU164B, GLU165A, GLU165B, GLU194A, GLU194B, GLU269A, GLU269B, GLU275A, GLU275B, GLU283A, GLU283B, GLU291A, GLU291B, GLU293A, GLU293B, GLU320A, GLU320B, GLU338A, GLU338B, GLU342A, GLU342B, GLU344A, GLU344B, GLU345A, GLU345B, GLU357A, GLU357B, GLU368A, GLU368B, GLU423A, GLU423B, GLU444A, GLU444B, GLU446A, GLU446B, GLU447A, GLU447B, GLY118A, GLY118B, GLY135A, GLY135B, GLY147A, GLY147B, GLY185A, GLY185B, GLY207A, GLY265A, GLY265B, GLY290A, GLY290B, GLY294A, GLY294B, GLY299A, GLY299B, GLY315A, GLY315B, GLY321A, GLY321B, GLY350A, GLY350B, GLY356A, GLY356B, GLY369A, GLY369B, GLY377A, GLY377B, GLY378A, GLY378B, GLY421A, GLY421B, GLY434A, GLY434B, GLY81A, GLY81B, GLY83A, GLY83B, GLY84A, GLY84B, HIS312A, HIS312B, HIS337A, HIS337B, HIS374A, HIS374B, HIS98A, HIS98B, ILE121A, ILE121B, ILE158A, ILE158B, ILE268A, ILE268B, ILE272A, ILE272B, ILE300A, ILE300B, ILE341A, ILE341B, ILE383A, ILE383B, ILE76A, ILE76B, ILE82A, ILE82B, LEU104A, LEU104B, LEU115A, LEU115B, LEU129A, LEU129B, LEU133A, LEU133B, LEU13A, LEU154A, LEU154B, LEU162A, LEU162B, LEU187A, LEU187B, LEU190A, LEU190B, LEU271A, LEU271B, LEU278B, LEU288A, LEU288B, LEU311A, LEU311B, LEU314A, LEU314B, LEU325A, LEU325B, LEU339A, LEU339B, LEU348A, LEU348B, LEU351A, LEU351B, LEU354A, LEU354B, LEU371A, LEU371B, LEU372A, LEU372B, LEU389A, LEU389B, LEU412A, LEU412B, LEU432A, LEU432B, LEU433A, LEU433B, LEU441A, LEU441B, LEU445A, LEU445B, LEU449A, LEU449B, LEU78A, LEU78B, LEU87A, LEU87B, LEU96A, LEU96B, LYS11A, LYS11B, LYS127A, LYS127B, LYS136A, LYS136B, LYS161A, LYS161B, LYS169A, LYS169B, LYS188A, LYS188B, LYS266A, LYS266B, LYS286A, LYS286B, LYS295A, LYS295B, LYS298A, LYS298B, LYS334A, LYS334B, LYS365A, LYS365B, LYS426A, LYS426B, LYS427A, LYS427B, LYS435A, LYS435B, LYS442A, LYS442B, LYS450A, LYS450B, PHE100A, PHE100B, PHE116A, PHE116B, PHE156A, PHE156B, PHE159A, PHE159B, PHE15A, PHE15B, PHE289A, PHE289B, PHE301A, PHE301B, PHE307A, PHE307B, PHE361A, PHE361B, PHE430A, PHE430B, PHE438A, PHE438B, PRO152A, PRO152B, PRO276A, PRO276B, PRO302A, PRO302B, PRO420A, PRO420B, PRO436A, PRO436B, SER105A, SER105B, SER10A, SER122A, SER122B, SER123A, SER123B, SER146A, SER14A, SER14B, SER292A, SER292B, SER303A, SER303B, SER304A, SER304B, SER308A, SER308B, SER313A, SER313B, SER335A, SER335B, SER343A, SER343B, SER375A, SER375B, SER85A, SER85B, SER99A, SER99B, THR103A, THR103B, THR124A, THR124B, THR148A, THR148B, THR149A, THR149B, THR150A, THR150B, THR189A, THR189B, THR267A, THR267B, THR309A, THR309B, THR336A, THR336B, THR340A, THR340B, THR358A, THR358B, THR364A, THR364B, THR370A, THR370B, TRP284A, TRP284B, TRP285A, TRP285B, TYR101A, TYR101B, TYR125A, TYR125B, TYR196A, TYR262A, TYR262B, TYR274A, TYR274B, TYR280A, TYR280B, TYR317A, TYR317B, TYR353A, TYR353B, TYR367A, TYR367B, TYR425A, TYR425B, TYR86A, TYR86B, TYR9A, VAL114A, VAL114B, VAL117A, VAL117B, VAL132A, VAL132B, VAL318A, VAL318B, VAL332A, VAL332B, VAL359A, VAL359B, VAL362A, VAL362B, VAL414A, VAL414B, VAL422A, VAL422B
• A-C: ALA260C, ARG322A, ARG322C, ARG323A, ARG323C, ASN263A, ASN263C, ASP324A, ASP324C, GLU320A, GLU320C, GLY265A, GLY265C, GLY321A, GLY321C, LEU261A, LEU261C, LYS264A, LYS264C, LYS266A, LYS266C, THR267A, THR267C, TYR262A, TYR262C
• A-D: ALA260A, ALA260D, ALA27A, ALA27D, ALA34A, ALA34D, ALA41A, ALA41D, ARG25A, ARG25D, ARG322A, ARG322D, ASN259A, ASN259D, ASN263A, ASN263D, ASN415A, ASN415D, ASP26A, ASP26D, ASP296A, ASP296D, ASP418A, ASP418D, GLN297A, GLN297D, GLU20A, GLU20D, GLY17A, GLY17D, GLY265A, GLY265D, GLY299A, GLY299D, GLY409A, GLY409D, GLY40A, GLY40D, GLY413A, GLY413D, GLY42A, GLY42D, HIS19A, HIS19D, HIS33A, HIS33D, ILE16A, ILE16D, ILE21A, ILE21D, ILE300A, LEU24A, LEU24D, LEU261A, LEU261D, LEU411A, LEU411D, LEU412A, LEU412D, LYS264A, LYS264D, LYS266A, LYS266D, LYS295A, LYS295D, LYS298A, LYS298D, LYS29A, LYS29D, PHE15A, PHE15D, PHE417A, PHE417D, PRO416A, PRO416D, PRO420A, PRO420D, SER14A, SER14D, THR22A, THR22D, THR267A, THR267D, THR31A, THR31D, THR39A, THR39D, TYR23A, TYR23D, TYR262A, TYR262D, TYR410A, TYR410D, VAL256A, VAL256D, VAL257A, VAL257D, VAL28A, VAL28D, VAL30A, VAL30D, VAL414A, VAL414D
• B-C: ALA260B, ALA260C, ALA27B, ALA27C, ALA34B, ALA34C, ALA41B, ALA41C, ARG25B, ARG25C, ARG322B, ARG322C, ASN259B, ASN259C, ASN263B, ASN263C, ASN415B, ASN415C, ASP26B, ASP26C, ASP296B, ASP296C, ASP418B, ASP418C, GLN297B, GLN297C, GLU20B, GLU20C, GLY17B, GLY17C, GLY265B, GLY265C, GLY299B, GLY299C, GLY409B, GLY409C, GLY40B, GLY40C, GLY413B, GLY413C, GLY42B, GLY42C, HIS19B, HIS19C, HIS33B, HIS33C, ILE16B, ILE16C, ILE21B, ILE21C, LEU24B, LEU24C, LEU261B, LEU261C, LEU411B, LEU411C, LEU412B, LEU412C, LYS264B, LYS264C, LYS266B, LYS266C, LYS295B, LYS295C, LYS298B, LYS298C, LYS29B, LYS29C, PHE15B, PHE15C, PHE417C, PRO416B, PRO416C, PRO420B, PRO420C, SER14B, SER14C, THR22C, THR267B, THR267C, THR31B, THR31C, THR39B, THR39C, TYR23B, TYR23C, TYR262B, TYR262C, TYR410B, TYR410C, VAL256B, VAL256C, VAL257B, VAL257C, VAL28B, VAL28C, VAL30B, VAL30C, VAL414B, VAL414C
• B-D: ARG322B, ARG322D, ARG323B, ARG323D, ASN263B, ASN263D, ASP324B, ASP324D, GLU320B, GLU320D, GLY265B, GLY265D, GLY321B, GLY321D, LEU261B, LEU261D, LYS264B, LYS264D, LYS266B, LYS266D, THR267B, THR267D, TYR262B, TYR262D
• B-E: ASP44B, GLU345E, PHE45B
• B-F: ARG173F, ASN193F, ASP192F, GLU170F, GLU440B, GLY195F, GLY437B, LYS427B, PRO436B
• C-D: ALA153C, ALA153D, ALA155C, ALA155D, ALA186C, ALA186D, ALA191C, ALA191D, ALA277C, ALA277D, ALA282C, ALA282D, ALA305C, ALA305D, ALA355C, ALA355D, ALA366C, ALA366D, ALA373C, ALA373D, ALA424C, ALA424D, ALA431C, ALA431D, ARG109C, ARG109D, ARG157C, ARG157D, ARG160C, ARG160D, ARG208C, ARG208D, ARG258C, ARG258D, ARG322C, ARG322D, ARG323C, ARG323D, ARG448C, ARG448D, ARG90C, ARG90D, ASN102C, ASN102D, ASN120C, ASN120D, ASN193C, ASN193D, ASN273C, ASN306C, ASN306D, ASN346C, ASN346D, ASN352C, ASN352D, ASN363C, ASN363D, ASN415C, ASN415D, ASN428C, ASN428D, ASN97C, ASN97D, ASP128C, ASP128D, ASP131C, ASP131D, ASP192C, ASP192D, ASP296C, ASP296D, ASP310C, ASP310D, ASP324C, ASP324D, ASP347C, ASP347D, ASP349C, ASP349D, ASP360C, ASP360D, ASP376C, ASP376D, ASP418C, ASP418D, GLN108C, GLN108D, GLN113C, GLN113D, GLN119C, GLN119D, GLN279C, GLN279D, GLN287C, GLN287D, GLN297C, GLN297D, GLN316C, GLN316D, GLN319C, GLN319D, GLN419C, GLN419D, GLU134C, GLU134D, GLU151C, GLU151D, GLU164C, GLU164D, GLU165C, GLU165D, GLU194C, GLU194D, GLU269C, GLU269D, GLU275C, GLU275D, GLU283C, GLU283D, GLU291C, GLU291D, GLU293C, GLU293D, GLU320C, GLU320D, GLU338C, GLU338D, GLU342C, GLU342D, GLU344C, GLU344D, GLU345C, GLU345D, GLU357C, GLU357D, GLU368C, GLU368D, GLU423C, GLU423D, GLU444C, GLU444D, GLU446C, GLU446D, GLU447C, GLU447D, GLY118C, GLY118D, GLY135C, GLY135D, GLY147C, GLY147D, GLY185C, GLY185D, GLY207C, GLY265C, GLY265D, GLY290C, GLY290D, GLY294C, GLY294D, GLY299C, GLY299D, GLY315C, GLY315D, GLY321C, GLY321D, GLY350C, GLY350D, GLY356C, GLY356D, GLY369C, GLY369D, GLY377C, GLY377D, GLY378C, GLY378D, GLY421C, GLY421D, GLY434C, GLY434D, GLY81C, GLY81D, GLY83C, GLY83D, GLY84C, GLY84D, HIS312C, HIS312D, HIS337C, HIS337D, HIS374C, HIS374D, HIS98C, HIS98D, ILE121C, ILE121D, ILE158C, ILE158D, ILE268C, ILE268D, ILE272D, ILE300C, ILE300D, ILE341C, ILE341D, ILE383C, ILE383D, ILE76C, ILE76D, ILE82C, ILE82D, LEU104C, LEU104D, LEU115C, LEU115D, LEU129C, LEU129D, LEU133C, LEU133D, LEU154C, LEU154D, LEU162C, LEU162D, LEU187C, LEU187D, LEU190C, LEU190D, LEU271C, LEU271D, LEU278C, LEU288C, LEU288D, LEU311C, LEU311D, LEU314C, LEU314D, LEU325C, LEU325D, LEU339C, LEU339D, LEU348C, LEU348D, LEU351C, LEU351D, LEU354C, LEU354D, LEU371C, LEU371D, LEU372C, LEU372D, LEU389C, LEU389D, LEU412C, LEU412D, LEU432C, LEU432D, LEU433C, LEU433D, LEU441C, LEU441D, LEU445C, LEU445D, LEU449C, LEU449D, LEU78C, LEU78D, LEU87C, LEU87D, LEU96C, LEU96D, LYS11C, LYS11D, LYS127C, LYS127D, LYS136C, LYS136D, LYS161C, LYS161D, LYS169C, LYS169D, LYS188C, LYS188D, LYS266C, LYS266D, LYS286C, LYS286D, LYS295C, LYS295D, LYS298C, LYS298D, LYS334C, LYS334D, LYS365C, LYS365D, LYS426C, LYS426D, LYS427C, LYS427D, LYS435C, LYS435D, LYS442C, LYS442D, LYS450C, LYS450D, PHE100C, PHE100D, PHE116C, PHE116D, PHE156C, PHE156D, PHE159C, PHE159D, PHE15C, PHE15D, PHE289C, PHE289D, PHE301C, PHE301D, PHE307C, PHE307D, PHE361C, PHE361D, PHE430C, PHE430D, PHE438C, PHE438D, PRO152C, PRO152D, PRO276C, PRO276D, PRO302C, PRO302D, PRO420C, PRO420D, PRO436C, PRO436D, SER105C, SER105D, SER10D, SER122C, SER122D, SER123C, SER123D, SER144D, SER146C, SER146D, SER14C, SER14D, SER292C, SER292D, SER303C, SER303D, SER304C, SER304D, SER308C, SER308D, SER313C, SER313D, SER335C, SER335D, SER343C, SER343D, SER375C, SER375D, SER85C, SER85D, SER99C, SER99D, THR103C, THR103D, THR124C, THR124D, THR148C, THR148D, THR149C, THR149D, THR150C, THR150D, THR189C, THR189D, THR267C, THR267D, THR309C, THR309D, THR336C, THR336D, THR340C, THR340D, THR358C, THR358D, THR364C, THR364D, THR370C, THR370D, TRP284C, TRP284D, TRP285C, TRP285D, TYR101C, TYR101D, TYR125C, TYR125D, TYR196C, TYR262C, TYR262D, TYR274C, TYR274D, TYR280C, TYR280D, TYR317C, TYR317D, TYR353C, TYR353D, TYR367C, TYR367D, TYR425C, TYR425D, TYR86C, TYR86D, VAL114C, VAL114D, VAL117C, VAL117D, VAL132C, VAL132D, VAL318C, VAL318D, VAL332C, VAL332D, VAL359C, VAL359D, VAL362C, VAL362D, VAL414C, VAL414D, VAL422C, VAL422D
• C-E: ASP347E, GLU18C, GLU247C, TYR353E
• C-F: ALA236C, ASN249C, ASP239C, ASP240C, GLN253C, GLU245C, GLU247C, GLU248C, GLU439F, GLU440F, GLU444F, GLY434F, GLY437F, HIS4C, LEU246C, LEU441F, LYS427F, LYS435F, LYS442F, PHE438F, PRO250C, PRO436F, THR243C, THR3C, TYR396C, TYR9C
• D-F: ALA183F, ALA443D, ARG184F, ARG448D, ASN43F, ASP181F, ASP203F, ASP204F, ASP418F, ASP44F, GLN419F, GLU439D, GLU440D, GLU444D, GLU446D, GLU447D, GLY434D, LEU445D, LEU449D, LYS145F, LYS182F, LYS38F, LYS442D, LYS450D, PHE417F, PHE45F, SER146F
• E-F: ALA153E, ALA153F, ALA155E, ALA155F, ALA186E, ALA186F, ALA191E, ALA191F, ALA277E, ALA277F, ALA282E, ALA305E, ALA305F, ALA355E, ALA355F, ALA366E, ALA366F, ALA373E, ALA373F, ALA424E, ALA424F, ALA431E, ALA431F, ARG109E, ARG109F, ARG157E, ARG157F, ARG160E, ARG160F, ARG208E, ARG208F, ARG258E, ARG258F, ARG322E, ARG322F, ARG323E, ARG323F, ARG448E, ARG448F, ARG90E, ARG90F, ASN102E, ASN102F, ASN120E, ASN120F, ASN193E, ASN193F, ASN263E, ASN263F, ASN306E, ASN306F, ASN346E, ASN346F, ASN352E, ASN352F, ASN363E, ASN363F, ASN415E, ASN415F, ASN428E, ASN428F, ASN97E, ASN97F, ASP128E, ASP128F, ASP131E, ASP131F, ASP192E, ASP192F, ASP296E, ASP296F, ASP310E, ASP310F, ASP324E, ASP324F, ASP347E, ASP347F, ASP349E, ASP349F, ASP360E, ASP360F, ASP376E, ASP376F, ASP418E, ASP418F, ASP8E, GLN108E, GLN108F, GLN113E, GLN113F, GLN119E, GLN119F, GLN279E, GLN279F, GLN287E, GLN287F, GLN297E, GLN297F, GLN316E, GLN316F, GLN319E, GLN319F, GLN419E, GLN419F, GLU134E, GLU134F, GLU151E, GLU151F, GLU164E, GLU165E, GLU165F, GLU194E, GLU194F, GLU269E, GLU269F, GLU275E, GLU275F, GLU283E, GLU283F, GLU291E, GLU291F, GLU293E, GLU293F, GLU320E, GLU320F, GLU338E, GLU338F, GLU342E, GLU342F, GLU344E, GLU344F, GLU345E, GLU345F, GLU357E, GLU357F, GLU368E, GLU368F, GLU423E, GLU423F, GLU444E, GLU444F, GLU446E, GLU446F, GLU447E, GLU447F, GLU94F, GLY118E, GLY118F, GLY135E, GLY135F, GLY147E, GLY147F, GLY185E, GLY185F, GLY207E, GLY207F, GLY265E, GLY265F, GLY290E, GLY290F, GLY294E, GLY294F, GLY299E, GLY299F, GLY315E, GLY315F, GLY321E, GLY321F, GLY350E, GLY350F, GLY356E, GLY356F, GLY369E, GLY369F, GLY377E, GLY377F, GLY378E, GLY378F, GLY421E, GLY421F, GLY434E, GLY434F, GLY81E, GLY81F, GLY83E, GLY83F, GLY84E, GLY84F, HIS312E, HIS312F, HIS337E, HIS337F, HIS374E, HIS374F, HIS98E, HIS98F, ILE121E, ILE121F, ILE158E, ILE158F, ILE268E, ILE268F, ILE272F, ILE300E, ILE300F, ILE341E, ILE341F, ILE383E, ILE383F, ILE76E, ILE76F, ILE82E, ILE82F, LEU104E, LEU104F, LEU115E, LEU115F, LEU129E, LEU129F, LEU133E, LEU133F, LEU154E, LEU154F, LEU162E, LEU162F, LEU187E, LEU187F, LEU190E, LEU190F, LEU271E, LEU271F, LEU278E, LEU288E, LEU288F, LEU311E, LEU311F, LEU314E, LEU314F, LEU325E, LEU325F, LEU339E, LEU339F, LEU348E, LEU348F, LEU351E, LEU351F, LEU354E, LEU354F, LEU371E, LEU371F, LEU372E, LEU372F, LEU389E, LEU389F, LEU412E, LEU412F, LEU432E, LEU432F, LEU433E, LEU433F, LEU441E, LEU441F, LEU445E, LEU445F, LEU449E, LEU449F, LEU78E, LEU78F, LEU87E, LEU87F, LEU96E, LEU96F, LYS11E, LYS11F, LYS127E, LYS127F, LYS136E, LYS136F, LYS161E, LYS161F, LYS169E, LYS169F, LYS188E, LYS188F, LYS266E, LYS266F, LYS286E, LYS286F, LYS295E, LYS295F, LYS298E, LYS298F, LYS334E, LYS334F, LYS365E, LYS365F, LYS426E, LYS426F, LYS427E, LYS427F, LYS435E, LYS435F, LYS442E, LYS442F, LYS450E, LYS450F, PHE100E, PHE100F, PHE116E, PHE116F, PHE156E, PHE156F, PHE159E, PHE159F, PHE15E, PHE15F, PHE289E, PHE289F, PHE301E, PHE301F, PHE307E, PHE307F, PHE361E, PHE361F, PHE430E, PHE430F, PHE438F, PRO152E, PRO152F, PRO276E, PRO276F, PRO302E, PRO302F, PRO420E, PRO420F, PRO436E, PRO436F, SER105E, SER105F, SER10E, SER10F, SER122E, SER122F, SER123E, SER123F, SER146E, SER146F, SER14E, SER14F, SER292E, SER292F, SER303E, SER303F, SER304E, SER304F, SER308E, SER308F, SER313E, SER313F, SER335E, SER335F, SER343E, SER343F, SER375E, SER375F, SER85E, SER85F, SER99E, SER99F, THR103E, THR103F, THR124E, THR124F, THR148E, THR148F, THR149E, THR149F, THR150E, THR150F, THR189E, THR189F, THR267E, THR267F, THR309E, THR309F, THR336E, THR336F, THR340E, THR340F, THR358E, THR358F, THR364E, THR364F, THR370E, THR370F, TRP284E, TRP284F, TRP285E, TRP285F, TYR101E, TYR101F, TYR125E, TYR125F, TYR262E, TYR262F, TYR274E, TYR274F, TYR280E, TYR280F, TYR317E, TYR317F, TYR353E, TYR353F, TYR367E, TYR367F, TYR425E, TYR425F, TYR86E, TYR86F, VAL114E, VAL114F, VAL117E, VAL117F, VAL132E, VAL132F, VAL318E, VAL318F, VAL332E, VAL332F, VAL359E, VAL359F, VAL362E, VAL362F, VAL414E, VAL414F, VAL422E, VAL422F