3IFQ

interction of plakoglobin and beta-catenin with desmosomal cadherins

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 294
  • Norm. En. per Res.: -3.726
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-43.6326	-89.8002	-263.0	-396.4328	143	16	11	12428	12	39	45
A-C	-134.6928	-167.6616	-803.376	-1105.7304	298	43	13	32231	12	76	44
A-D	0.0	0.0	-0.0395	-0.0395	4	0	0	5	0	1	3
B-C	0.0	0.0	-0.0122	-0.0122	5	0	0	6	0	0	2
B-D	-128.4408	-183.4056	-783.597	-1095.4435	294	48	15	31606	12	77	50

Interface residues

• A-B: ALA126A, ALA126B, ALA137A, ALA137B, ALA140B, ALA174A, ALA174B, ALA178A, ALA178B, ALA221B, ALA522A, ALA522B, ALA534A, ALA534B, ALA543A, ALA544A, ARG176A, ARG176B, ARG177A, ARG177B, ARG216A, ARG216B, ARG526A, ARG526B, ARG540A, ARG540B, ARG582A, ARG582B, ASN132A, ASN132B, ASN493A, ASN493B, ASN584A, ASN584B, ASP135A, ASP135B, ASP136A, ASP136B, ASP537A, ASP537B, ASP552A, ASP552B, GLN134A, GLN134B, GLN257B, GLN494A, GLN529A, GLN529B, GLN536A, GLN536B, GLN539A, GLN539B, GLN547A, GLN548A, GLN591A, GLN591B, GLU138A, GLU138B, GLU173A, GLU173B, GLU217A, GLU217B, GLU258B, GLU579A, GLU579B, GLU624B, GLY181A, GLY181B, GLY218A, GLY218B, HIS129A, HIS129B, HIS214B, HIS215A, HIS215B, HIS535A, HIS535B, HIS541A, ILE127A, ILE127B, ILE131A, ILE131B, ILE524A, ILE524B, ILE580B, LEU130A, LEU130B, LEU144B, LEU179B, LEU219B, LEU220B, LEU255A, LEU527A, LEU527B, LEU530A, LEU530B, LEU531A, LEU531B, LEU567B, LEU583A, LEU583B, LEU588A, LEU588B, LYS224B, LYS533A, LYS533B, MET180A, MET180B, MET556A, PHE223B, PHE581A, PHE581B, PHE589B, PRO183B, PRO492A, PRO492B, PRO525A, PRO525B, PRO549A, PRO587A, PRO587B, SER175B, SER182B, THR141A, THR141B, THR546A, THR551A, THR551B, THR585A, THR585B, TRP495A, TRP495B, TYR133A, TYR133B, TYR256A, TYR256B, TYR550A, VAL128A, VAL128B, VAL528A, VAL528B, VAL532A, VAL532B
• A-C: ALA137A, ALA140A, ALA143A, ALA162A, ALA163A, ALA178A, ALA246A, ALA286A, ALA296A, ALA383A, ALA455A, ALA458A, ALA500A, ALA566A, ALA605A, ALA634C, ALA642A, ALA645A, ALA646A, ALA647A, ALA648C, ALA663C, ALA664C, ALA670C, ALA688C, ALA689C, ALA719C, ARG142A, ARG176A, ARG333A, ARG367A, ARG377A, ARG460A, ARG465A, ARG506A, ARG572A, ARG602A, ARG630C, ARG644C, ARG646C, ARG651A, ARG661A, ARG663A, ARG714C, ASN167A, ASN211A, ASN281A, ASN299A, ASN371A, ASN378A, ASN406A, ASN417A, ASN421A, ASN422A, ASN507A, ASN599A, ASN631C, ASN638A, ASN649C, ASN655C, ASN660C, ASN670A, ASN695C, ASN713C, ASP135A, ASP136A, ASP153A, ASP155A, ASP290A, ASP381A, ASP449A, ASP450A, ASP552A, ASP632C, ASP651C, ASP658C, ASP665C, ASP667C, ASP674C, ASP680C, ASP702C, ASP704C, ASP706C, ASP720C, CYS291A, CYS341A, CYS410A, CYS420A, CYS457A, CYS609A, GLN168A, GLN293A, GLN300A, GLN370A, GLN494A, GLN613A, GLN642C, GLN703C, GLU138A, GLU146A, GLU154A, GLU240A, GLU258A, GLU325A, GLU453A, GLU558A, GLU561A, GLU610A, GLU639A, GLU652C, GLU659C, GLU667A, GLU682C, GLU687C, GLU710C, GLY298A, GLY413A, GLY503A, GLY553A, GLY562A, GLY565A, GLY606A, GLY640A, GLY654C, GLY683C, GLY685C, GLY712C, GLY723C, HIS129A, HIS210A, HIS214A, HIS251A, HIS461A, HIS466A, HIS568A, HIS635A, ILE165A, ILE247A, ILE287A, ILE451A, ILE502A, ILE505A, ILE569A, ILE600A, ILE653C, ILE657C, LEU139A, LEU144A, LEU147A, LEU150A, LEU151A, LEU169A, LEU179A, LEU243A, LEU254A, LEU255A, LEU285A, LEU294A, LEU327A, LEU335A, LEU338A, LEU373A, LEU376A, LEU379A, LEU415A, LEU418A, LEU462A, LEU497A, LEU504A, LEU508A, LEU510A, LEU634A, LEU637C, LEU649A, LEU661C, LEU668A, LEU672A, LEU676C, LEU677C, LEU691C, LEU694C, LEU708C, LEU718C, LYS149A, LYS161A, LYS171A, LYS172A, LYS261A, LYS283A, LYS303A, LYS326A, LYS336A, LYS345A, LYS385A, LYS426A, LYS499A, LYS662A, LYS662C, LYS716C, LYS717C, MET164A, MET638C, MET721C, PHE244A, PHE284A, PHE650A, PHE656C, PHE673A, PHE679C, PHE715C, PRO145A, PRO282A, PRO342A, PRO454A, PRO467A, PRO496A, PRO635C, PRO641C, PRO647C, PRO650C, PRO668C, PRO671C, PRO672C, SER170A, SER175A, SER241A, SER339A, SER380A, SER416A, SER423A, SER464A, SER636A, SER665A, SER666C, SER671A, SER675C, SER690C, SER693C, SER696C, THR141A, THR148A, THR160A, THR248A, THR249A, THR288A, THR289A, THR330A, THR331A, THR375A, THR384A, THR409A, THR412A, THR414A, THR419A, THR452A, THR463A, THR501A, THR629C, THR636C, THR641A, THR643A, THR669A, THR669C, TRP329A, TRP374A, TRP495A, TRP711C, TYR245A, TYR256A, TYR297A, TYR324A, TYR643C, TYR644A, TYR673C, TYR681C, TYR705C, TYR707C, TYR722C, VAL128A, VAL157A, VAL158A, VAL159A, VAL166A, VAL334A, VAL337A, VAL340A, VAL382A, VAL456A, VAL554A, VAL597A, VAL603A, VAL628C, VAL633C, VAL640C, VAL648A, VAL664A, VAL666A, VAL678C
• A-D: ALA689D, ASP447A, PRO492A, SER690D
• B-C: ALA689C, ASN493B, ASP447B, PRO492B, SER690C
• B-D: ALA126B, ALA140B, ALA143B, ALA162B, ALA163B, ALA246B, ALA286B, ALA296B, ALA383B, ALA455B, ALA458B, ALA500B, ALA566B, ALA605B, ALA634D, ALA642B, ALA645B, ALA646B, ALA647B, ALA648D, ALA663D, ALA664D, ALA670D, ALA688D, ALA689D, ALA719D, ARG142B, ARG176B, ARG333B, ARG367B, ARG377B, ARG460B, ARG465B, ARG506B, ARG572B, ARG602B, ARG630D, ARG644D, ARG646D, ARG651B, ARG714D, ASN167B, ASN211B, ASN281B, ASN299B, ASN371B, ASN378B, ASN406B, ASN417B, ASN421B, ASN422B, ASN507B, ASN599B, ASN631D, ASN638B, ASN649D, ASN655D, ASN660D, ASN670B, ASN695D, ASN713D, ASP136B, ASP153B, ASP155B, ASP290B, ASP381B, ASP449B, ASP450B, ASP552B, ASP632D, ASP651D, ASP658D, ASP665D, ASP667D, ASP674D, ASP680D, ASP700D, ASP702D, ASP704D, ASP706D, ASP720D, CYS291B, CYS341B, CYS410B, CYS420B, CYS457B, CYS609B, GLN168B, GLN293B, GLN300B, GLN370B, GLN494B, GLN642D, GLN701D, GLN703D, GLU146B, GLU154B, GLU240B, GLU258B, GLU453B, GLU558B, GLU561B, GLU610B, GLU639B, GLU652D, GLU659D, GLU667B, GLU682D, GLU687D, GLU710D, GLY298B, GLY413B, GLY503B, GLY553B, GLY562B, GLY565B, GLY606B, GLY640B, GLY654D, GLY683D, GLY685D, GLY712D, HIS129B, HIS210B, HIS214B, HIS251B, HIS461B, HIS466B, HIS568B, HIS635B, ILE127B, ILE165B, ILE247B, ILE287B, ILE451B, ILE502B, ILE505B, ILE569B, ILE600B, ILE653D, ILE657D, LEU139B, LEU144B, LEU147B, LEU150B, LEU151B, LEU169B, LEU243B, LEU254B, LEU255B, LEU285B, LEU294B, LEU327B, LEU335B, LEU338B, LEU373B, LEU376B, LEU379B, LEU415B, LEU418B, LEU462B, LEU497B, LEU504B, LEU508B, LEU510B, LEU633B, LEU634B, LEU637D, LEU649B, LEU661D, LEU668B, LEU672B, LEU676D, LEU677D, LEU691D, LEU694D, LEU708D, LEU718D, LYS149B, LYS161B, LYS171B, LYS172B, LYS283B, LYS303B, LYS326B, LYS336B, LYS345B, LYS385B, LYS426B, LYS499B, LYS662B, LYS662D, LYS716D, LYS717D, MET164B, MET631B, MET638D, MET721D, PHE244B, PHE284B, PHE650B, PHE656D, PHE673B, PHE679D, PHE715D, PRO145B, PRO156B, PRO282B, PRO342B, PRO454B, PRO467B, PRO496B, PRO635D, PRO641D, PRO645D, PRO647D, PRO650D, PRO668D, PRO671D, PRO672D, SER170B, SER175B, SER207B, SER241B, SER339B, SER380B, SER416B, SER423B, SER464B, SER636B, SER639D, SER665B, SER666D, SER671B, SER675D, SER690D, SER693D, SER699D, THR148B, THR160B, THR206B, THR248B, THR249B, THR288B, THR289B, THR330B, THR331B, THR375B, THR384B, THR409B, THR412B, THR414B, THR419B, THR463B, THR551B, THR629D, THR636D, THR641B, THR643B, THR669B, THR669D, TRP329B, TRP374B, TRP495B, TRP711D, TYR245B, TYR256B, TYR297B, TYR324B, TYR643D, TYR644B, TYR673D, TYR681D, TYR705D, TYR707D, VAL128B, VAL157B, VAL158B, VAL159B, VAL166B, VAL337B, VAL340B, VAL382B, VAL456B, VAL554B, VAL597B, VAL603B, VAL628D, VAL633D, VAL640D, VAL648B, VAL664B, VAL666B, VAL678D