3IFG

crystal structure of succinate-semialdehyde dehydrogenase from burkholderia pseudomallei, part 1 of 2

• Total interactions analyzed: 120
• Total true interactions: 38
• Strongest Interaction:
  • Chains: I-J
  • Int. Res.: 98
  • Norm. En. per Res.: -5.2184
• Hub Node: E(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-87.9858	-201.8249	-196.398	-486.2088	99	13	0	7800	18	50	39
A-C	-73.945	-25.4809	-238.934	-338.3599	103	15	6	9633	3	38	39
A-D	-254.1657	-36.4267	-691.187	-981.7794	253	45	33	29657	8	56	50
A-J	-20.0463	-1.737	-61.6906	-83.4738	45	2	1	2319	4	25	21
B-C	-262.0862	4.0442	-694.303	-952.345	250	45	33	30017	10	56	51
B-D	-52.0985	-19.6216	-223.956	-295.6761	100	10	5	9406	2	38	39
C-D	-84.4355	-192.3281	-204.516	-481.2796	97	14	0	7996	22	51	42
C-I	0.0	0.0	-0.0008	-0.0008	2	0	0	2	0	1	0
C-J	0.0	36.4687	-1.4552	35.0135	10	0	0	130	0	10	10
C-L	-9.3805	2.075	-60.9338	-68.2393	47	2	1	2556	5	24	24
E-F	-73.0612	-206.5247	-189.133	-468.7188	97	12	0	7871	18	51	38
E-G	-82.3379	-32.4806	-243.664	-358.4825	104	10	6	9679	4	39	41
E-H	-259.3454	-47.3956	-689.01	-995.751	250	45	33	29575	9	56	51
E-I	0.0	10.2288	-0.3121	9.9168	7	0	0	64	0	7	5
E-J	0.0	-7.9425	-18.6877	-26.6302	29	2	0	1093	0	14	15
E-N	-18.5687	1.4698	-57.894	-74.9929	45	2	1	2293	5	23	21
F-G	-231.8686	5.1894	-672.504	-899.1832	246	39	33	29579	10	56	49
F-H	-71.9358	-34.7598	-228.673	-335.3686	103	11	5	9341	4	38	40
G-H	-75.6869	-197.2146	-200.895	-473.7965	100	14	0	7997	17	50	40
G-I	0.0	-18.2461	-24.106	-42.3521	36	0	0	1340	3	18	21
G-M	0.0	0.0	-0.0061	-0.0061	2	0	0	6	0	1	0
G-N	0.0	37.947	-1.5159	36.4311	9	0	0	117	0	10	11
G-P	-9.2951	-4.2805			8
H-N	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	1	0
I-J	-91.8127	-215.9201	-203.672	-511.4047	98	18	0	7904	19	50	38
I-K	-54.4025	-15.9091	-219.296	-289.6076	98	9	5	9216	0	39	40
I-L	-205.5458	-35.4907	-657.291	-898.3275	239	39	31	29170	8	55	50
I-N	0.0	0.0	-1.6488	-1.6488	7	0	0	129	0	11	5
I-P	0.0	4.0601			4
J-K	-227.9983	4.3001	-677.125	-900.8232	249	40	31	29372	6	54	50
J-L	-61.6422	-28.4777	-227.447	-317.5669	100	12	5	9348	3	39	38
K-L	-78.2695	-197.1313	-203.251	-478.6518	98	15	0	7888	18	50	39
M-N	-73.9315	-195.133	-195.4	-464.4644	100	14	0	7723	16	50	38
M-O	-61.3436	-23.6736	0.0	-85.0171	19	0	0	0	0	0	0
M-P	-217.7868	-37.9081			46
N-O	-224.2194	1.0205	0.0	-223.1989	47	0	0	0	0	0	0
N-P	-66.8906	-27.7779			19
O-P	-72.6041	-191.305			24

Interface residues

• A-B: ALA112A, ALA112B, ALA115A, ALA115B, ALA122A, ALA122B, ALA129A, ALA129B, ALA483A, ALA483B, ALA71A, ALA71B, ALA75A, ALA75B, ALA76A, ALA76B, ARG127A, ARG127B, ARG141A, ARG141B, ARG427A, ARG427B, ARG430A, ARG430B, ARG79A, ARG79B, ASN449A, ASN449B, ASP131B, ASP424B, ASP83A, ASP83B, GLU119A, GLU119B, GLU123A, GLU123B, GLU124A, GLU124B, GLU433A, GLU433B, GLU450A, GLU450B, GLY125A, GLY125B, GLY130A, GLY130B, GLY426A, GLY426B, HIS468A, HIS468B, ILE142A, ILE142B, ILE425A, ILE425B, ILE86A, ILE86B, LEU133A, LEU133B, LEU480A, LEU480B, LYS126A, LYS126B, LYS140A, LYS140B, LYS72A, LYS72B, PHE117A, PHE117B, PHE121A, PHE121B, PHE82A, PHE82B, SER116A, SER116B, SER467A, SER467B, THR132A, THR132B, THR70A, THR70B, TRP120A, TRP120B, TRP429A, TRP429B, TYR113A, TYR113B, TYR469A, TYR469B, VAL128A, VAL128B, VAL143A, VAL143B, VAL428B, VAL451A, VAL451B, VAL482A, VAL482B, VAL484A, VAL484B
• A-C: ALA129A, ALA129C, ALA138A, ALA138C, ALA174C, ALA175C, ALA71A, ALA71C, ARG127A, ARG127C, ARG141A, ARG141C, ARG423A, ARG423C, ARG427A, ARG427C, ARG430A, ARG430C, ARG67A, ARG67C, ARG74A, ARG74C, ASN139A, ASN139C, ASN443A, ASN443C, ASP131A, ASP131C, ASP137A, ASP137C, ASP269A, ASP269C, ASP271C, ASP424A, ASP424C, GLU123A, GLU123C, GLU124A, GLU124C, GLU73A, GLU73C, GLY125A, GLY125C, GLY130A, GLY130C, GLY426A, GLY426C, ILE142A, ILE142C, ILE425A, ILE425C, ILE442A, ILE442C, ILE471A, ILE471C, LEU133A, LEU133C, LEU420C, LEU480A, LEU480C, LYS126A, LYS126C, LYS140A, LYS140C, LYS146A, LYS146C, LYS478A, LYS478C, LYS69A, LYS69C, LYS72A, LYS72C, MET68A, MET68C, PRO134A, PRO134C, PRO136A, PRO136C, SER422A, SER422C, THR132A, THR132C, THR135A, THR135C, THR70A, THR70C, TRP429A, TRP429C, TYR421A, TYR421C, VAL128A, VAL128C, VAL143A, VAL143C, VAL144A, VAL144C, VAL145A, VAL145C, VAL428A, VAL428C, VAL475A, VAL475C, VAL484A
• A-D: ALA129A, ALA129D, ALA238A, ALA238D, ALA245A, ALA245D, ALA248A, ALA248D, ALA274A, ALA274D, ALA281A, ALA281D, ALA417A, ALA417D, ALA418A, ALA418D, ALA432A, ALA432D, ALA434A, ALA434D, ALA452A, ALA452D, ALA483A, ALA483D, ARG141A, ARG141D, ARG229A, ARG229D, ARG241A, ARG241D, ARG285D, ARG423A, ARG423D, ARG430A, ARG430D, ARG464A, ARG464D, ARG67A, ARG67D, ASN139A, ASN139D, ASN225A, ASN225D, ASN410A, ASN410D, ASN443A, ASN443D, ASN449A, ASN449D, ASP131A, ASP131D, ASP137A, ASP137D, ASP472A, ASP472D, ASP473A, ASP473D, CYS481A, CYS481D, GLN246A, GLN246D, GLN459A, GLN459D, GLN60A, GLU124A, GLU147A, GLU147D, GLU257A, GLU257D, GLU413A, GLU413D, GLU433A, GLU433D, GLU436A, GLU436D, GLU450A, GLU450D, GLU465D, GLY130A, GLY130D, GLY150A, GLY150D, GLY240A, GLY240D, GLY259A, GLY259D, GLY278A, GLY415A, GLY415D, GLY438A, GLY438D, GLY441A, GLY441D, GLY445A, GLY445D, GLY455A, GLY455D, GLY456A, GLY456D, GLY461A, GLY461D, GLY463A, GLY463D, GLY466D, HIS468A, HIS468D, ILE142A, ILE142D, ILE149A, ILE149D, ILE227A, ILE227D, ILE425A, ILE425D, ILE442A, ILE442D, ILE447A, ILE447D, ILE477A, ILE477D, LEU133A, LEU133D, LEU231A, LEU231D, LEU242A, LEU242D, LEU243A, LEU243D, LEU254A, LEU254D, LEU256A, LEU256D, LEU258A, LEU258D, LEU416A, LEU416D, LEU420A, LEU420D, LEU435A, LEU435D, LEU446A, LEU446D, LEU462A, LEU462D, LEU480A, LEU480D, LYS140A, LYS140D, LYS146A, LYS146D, LYS230A, LYS230D, LYS252A, LYS252D, LYS253A, LYS253D, LYS458A, LYS458D, LYS478A, LYS478D, MET244A, MET244D, MET439A, MET439D, PHE414A, PHE414D, PHE454A, PHE454D, PRO134A, PRO134D, PRO136A, PRO136D, PRO148A, PRO148D, PRO226A, PRO226D, PRO249A, PRO249D, PRO453A, PRO453D, SER116A, SER116D, SER236A, SER236D, SER247A, SER247D, SER448A, SER448D, SER460A, SER460D, SER467A, SER467D, THR132A, THR132D, THR135A, THR135D, THR237A, THR237D, THR250A, THR250D, THR412A, THR412D, THR444A, THR444D, TRP120A, TRP120D, TRP429A, TRP429D, TRP63A, TRP63D, TYR113D, TYR419A, TYR419D, TYR421A, TYR421D, TYR437A, TYR437D, TYR469A, TYR469D, TYR479A, TYR479D, VAL128A, VAL143A, VAL143D, VAL144A, VAL144D, VAL145A, VAL145D, VAL228A, VAL228D, VAL239D, VAL251A, VAL251D, VAL292A, VAL292D, VAL428A, VAL428D, VAL431A, VAL431D, VAL440A, VAL440D, VAL451A, VAL451D, VAL457A, VAL457D, VAL475A, VAL475D, VAL476A, VAL476D, VAL482A, VAL482D, VAL484A, VAL484D
• A-J: ALA306J, ALA308J, ALA312J, ALA313J, ALA354J, ALA400A, ARG302A, ARG398A, ARG398J, ARG407A, ARG427A, ARG430A, ASP268A, ASP269A, ASP305J, ASP309J, ASP424A, GLU301A, GLU402A, GLU403A, GLU404A, GLY353J, GLY359J, GLY377J, HIS300A, LEU356J, LEU375J, LEU396J, LYS310J, LYS317J, MET357J, PHE267A, PHE307J, PHE399A, PRO372J, SER316J, SER355J, SER401A, THR358J, THR376J, TYR304J, VAL303A, VAL303J, VAL315J, VAL374J
• B-C: ALA129B, ALA129C, ALA238B, ALA238C, ALA245B, ALA245C, ALA248B, ALA248C, ALA274B, ALA274C, ALA281B, ALA281C, ALA417B, ALA417C, ALA418B, ALA418C, ALA432B, ALA432C, ALA434B, ALA434C, ALA452B, ALA452C, ALA483B, ALA483C, ARG141B, ARG141C, ARG229B, ARG229C, ARG241B, ARG241C, ARG285B, ARG423B, ARG423C, ARG430B, ARG430C, ARG464B, ARG464C, ARG67B, ARG67C, ASN139B, ASN139C, ASN225C, ASN410B, ASN410C, ASN443B, ASN443C, ASN449B, ASN449C, ASP131B, ASP131C, ASP137B, ASP137C, ASP472B, ASP472C, ASP473B, CYS481B, CYS481C, GLN246B, GLN246C, GLN459B, GLN459C, GLN60C, GLU147B, GLU147C, GLU257B, GLU257C, GLU413B, GLU413C, GLU433B, GLU433C, GLU436B, GLU436C, GLU450B, GLU450C, GLU465C, GLY130B, GLY130C, GLY150B, GLY150C, GLY240B, GLY240C, GLY259C, GLY278B, GLY278C, GLY415B, GLY438B, GLY438C, GLY441B, GLY441C, GLY445B, GLY445C, GLY455B, GLY455C, GLY456B, GLY456C, GLY461B, GLY461C, GLY463B, GLY463C, GLY466C, HIS468B, HIS468C, ILE142B, ILE142C, ILE149B, ILE149C, ILE425B, ILE425C, ILE442B, ILE442C, ILE447B, ILE447C, ILE477B, ILE477C, LEU133B, LEU133C, LEU231B, LEU231C, LEU242B, LEU242C, LEU243B, LEU243C, LEU254B, LEU254C, LEU256B, LEU256C, LEU258B, LEU258C, LEU416B, LEU416C, LEU420B, LEU420C, LEU435B, LEU435C, LEU446B, LEU446C, LEU462B, LEU462C, LEU480B, LEU480C, LYS140B, LYS140C, LYS146B, LYS146C, LYS230B, LYS230C, LYS252B, LYS252C, LYS253B, LYS253C, LYS458B, LYS458C, LYS478B, LYS478C, MET244B, MET244C, MET439B, MET439C, PHE233B, PHE233C, PHE414B, PHE414C, PHE454B, PHE454C, PRO134B, PRO134C, PRO136B, PRO136C, PRO148B, PRO148C, PRO226B, PRO226C, PRO249B, PRO249C, PRO453B, PRO453C, SER116B, SER116C, SER236B, SER247B, SER247C, SER448B, SER448C, SER460B, SER460C, SER467B, SER467C, THR132B, THR132C, THR135B, THR135C, THR237B, THR237C, THR250B, THR250C, THR412B, THR412C, THR444B, THR444C, TRP120B, TRP120C, TRP429B, TRP429C, TRP63B, TRP63C, TYR113B, TYR113C, TYR419B, TYR419C, TYR421B, TYR421C, TYR437B, TYR437C, TYR469B, TYR469C, TYR479B, TYR479C, VAL128C, VAL143B, VAL143C, VAL144B, VAL144C, VAL145B, VAL145C, VAL228B, VAL228C, VAL239B, VAL239C, VAL251B, VAL251C, VAL292B, VAL292C, VAL428B, VAL428C, VAL431B, VAL431C, VAL440B, VAL440C, VAL451B, VAL451C, VAL457B, VAL457C, VAL475B, VAL475C, VAL476B, VAL476C, VAL482B, VAL482C, VAL484B, VAL484C
• B-D: ALA129B, ALA129D, ALA138B, ALA138D, ALA174B, ALA71B, ALA71D, ARG127B, ARG127D, ARG141B, ARG141D, ARG423B, ARG423D, ARG427B, ARG427D, ARG430B, ARG430D, ARG67B, ARG67D, ARG74B, ARG74D, ASN139B, ASN139D, ASN443B, ASN443D, ASP131B, ASP131D, ASP137B, ASP137D, ASP269B, ASP269D, ASP271B, ASP424B, ASP424D, GLU123B, GLU123D, GLU124B, GLU124D, GLU73B, GLU73D, GLY125B, GLY125D, GLY130B, GLY130D, GLY426B, GLY426D, ILE142B, ILE142D, ILE425B, ILE425D, ILE442B, ILE442D, ILE471B, LEU133B, LEU133D, LEU420B, LEU420D, LEU480B, LEU480D, LYS126B, LYS126D, LYS140B, LYS140D, LYS146B, LYS146D, LYS478B, LYS478D, LYS69B, LYS69D, LYS72B, LYS72D, MET68B, MET68D, PRO134B, PRO134D, PRO136B, PRO136D, SER422B, SER422D, THR132B, THR132D, THR135B, THR135D, THR70B, THR70D, TRP429B, TRP429D, TYR421B, TYR421D, VAL128B, VAL128D, VAL143B, VAL143D, VAL144B, VAL144D, VAL145B, VAL145D, VAL428B, VAL428D, VAL475B
• C-D: ALA112C, ALA112D, ALA115C, ALA115D, ALA122C, ALA122D, ALA129C, ALA129D, ALA483C, ALA483D, ALA71C, ALA71D, ALA75C, ALA75D, ALA76C, ALA76D, ARG127C, ARG127D, ARG141C, ARG141D, ARG427C, ARG427D, ARG430C, ARG430D, ARG79C, ARG79D, ASN449C, ASN449D, ASP131D, ASP83C, ASP83D, GLU119C, GLU119D, GLU123C, GLU123D, GLU124C, GLU124D, GLU433C, GLU433D, GLU450C, GLU450D, GLY125C, GLY125D, GLY130C, GLY130D, GLY426C, GLY426D, HIS468C, HIS468D, ILE142C, ILE142D, ILE425C, ILE425D, LEU133C, LEU133D, LEU480C, LEU480D, LYS126C, LYS126D, LYS140C, LYS140D, LYS72C, LYS72D, PHE117C, PHE117D, PHE121C, PHE121D, PHE82C, PHE82D, SER116C, SER116D, SER467C, SER467D, THR132C, THR132D, THR135C, THR70D, TRP120C, TRP120D, TRP429C, TRP429D, TYR113C, TYR113D, TYR469C, VAL128C, VAL128D, VAL143C, VAL143D, VAL428C, VAL431C, VAL431D, VAL451C, VAL451D, VAL482C, VAL482D, VAL484C, VAL484D
• C-I: LYS317C, MET68I
• C-J: ALA274C, ALA274J, ARG423C, ARG423J, ASP271C, ASP271J, ASP273C, ASP273J, LYS310C, LYS310J
• C-L: ALA306C, ALA308C, ALA312C, ALA313C, ALA354C, ALA400L, ARG302L, ARG398C, ARG398L, ARG407L, ARG427L, ARG430L, ASP268L, ASP269L, ASP305C, ASP309C, ASP424L, GLU301L, GLU371C, GLU402L, GLU403L, GLU404L, GLY353C, GLY359C, GLY360C, GLY377C, HIS300L, LEU356C, LEU375C, LEU396C, LEU405L, LYS310C, LYS317C, MET357C, PHE267L, PHE307C, PHE399L, SER316C, SER355C, SER401L, THR358C, THR376C, TYR304C, VAL303C, VAL303L, VAL315C, VAL374C
• E-F: ALA112E, ALA112F, ALA115E, ALA115F, ALA122E, ALA122F, ALA129E, ALA129F, ALA138E, ALA483E, ALA483F, ALA71E, ALA71F, ALA75E, ALA75F, ALA76E, ALA76F, ARG127E, ARG127F, ARG141E, ARG141F, ARG427E, ARG427F, ARG430E, ARG430F, ARG79E, ARG79F, ASN449E, ASN449F, ASP83E, ASP83F, GLU119E, GLU119F, GLU123E, GLU123F, GLU124E, GLU124F, GLU433E, GLU433F, GLU450E, GLU450F, GLY125E, GLY125F, GLY130F, GLY426E, GLY426F, HIS468E, HIS468F, ILE142E, ILE142F, ILE425E, ILE425F, ILE86E, LEU133E, LEU133F, LEU480E, LEU480F, LYS126E, LYS126F, LYS140E, LYS140F, LYS72E, LYS72F, PHE117E, PHE117F, PHE121E, PHE121F, PHE82E, PHE82F, SER116E, SER116F, SER467E, SER467F, THR132E, THR132F, THR70E, THR70F, TRP120E, TRP120F, TRP429E, TRP429F, TYR113E, TYR113F, TYR469E, TYR469F, VAL128E, VAL128F, VAL143E, VAL143F, VAL428F, VAL431F, VAL451E, VAL451F, VAL482E, VAL482F, VAL484E, VAL484F
• E-G: ALA129E, ALA129G, ALA138E, ALA138G, ALA174E, ALA174G, ALA71E, ALA71G, ARG127E, ARG127G, ARG141E, ARG141G, ARG423E, ARG423G, ARG427E, ARG427G, ARG430E, ARG430G, ARG67E, ARG67G, ARG74E, ARG74G, ASN139E, ASN139G, ASN443E, ASN443G, ASP131E, ASP131G, ASP137E, ASP137G, ASP269E, ASP269G, ASP424E, ASP424G, GLU123E, GLU123G, GLU124E, GLU124G, GLU73E, GLU73G, GLY125E, GLY125G, GLY130E, GLY130G, GLY426E, GLY426G, ILE142E, ILE142G, ILE425E, ILE425G, ILE442E, ILE442G, ILE471E, ILE471G, LEU133E, LEU133G, LEU420E, LEU420G, LEU480E, LEU480G, LYS126E, LYS126G, LYS140E, LYS140G, LYS146E, LYS146G, LYS478E, LYS478G, LYS69E, LYS69G, LYS72E, LYS72G, MET68E, MET68G, PRO134E, PRO134G, PRO136E, PRO136G, SER422E, SER422G, THR132E, THR132G, THR135E, THR135G, THR70E, THR70G, TRP429E, TRP429G, TYR421E, TYR421G, VAL128E, VAL128G, VAL143E, VAL143G, VAL144E, VAL144G, VAL145E, VAL145G, VAL428E, VAL428G, VAL475E, VAL475G, VAL482E, VAL482G
• E-H: ALA129E, ALA129H, ALA238E, ALA238H, ALA245E, ALA245H, ALA248E, ALA248H, ALA274E, ALA274H, ALA281E, ALA281H, ALA417E, ALA417H, ALA418E, ALA418H, ALA432E, ALA432H, ALA434E, ALA434H, ALA452E, ALA452H, ALA483E, ALA483H, ARG141E, ARG141H, ARG229E, ARG229H, ARG241E, ARG241H, ARG285E, ARG423E, ARG423H, ARG430E, ARG430H, ARG464E, ARG464H, ARG67E, ARG67H, ASN139E, ASN139H, ASN225E, ASN225H, ASN410E, ASN410H, ASN443E, ASN443H, ASN449E, ASN449H, ASP131E, ASP131H, ASP137E, ASP137H, ASP472E, ASP472H, ASP473H, CYS481E, CYS481H, GLN246E, GLN246H, GLN459E, GLN459H, GLN60E, GLU147E, GLU147H, GLU257H, GLU413E, GLU413H, GLU433E, GLU433H, GLU436E, GLU436H, GLU450E, GLU450H, GLU465E, GLY130E, GLY130H, GLY150E, GLY150H, GLY240E, GLY240H, GLY259H, GLY278E, GLY278H, GLY415E, GLY415H, GLY438E, GLY438H, GLY441E, GLY441H, GLY445E, GLY445H, GLY455E, GLY455H, GLY456E, GLY456H, GLY461E, GLY461H, GLY463E, GLY463H, GLY466E, HIS468E, HIS468H, ILE142E, ILE142H, ILE149E, ILE149H, ILE227E, ILE227H, ILE425E, ILE425H, ILE442E, ILE442H, ILE447E, ILE447H, ILE477E, ILE477H, LEU133E, LEU133H, LEU231E, LEU231H, LEU242E, LEU242H, LEU243E, LEU243H, LEU254E, LEU254H, LEU256E, LEU256H, LEU258E, LEU258H, LEU416E, LEU416H, LEU420E, LEU420H, LEU435E, LEU435H, LEU446E, LEU446H, LEU462E, LEU462H, LEU480E, LEU480H, LYS140E, LYS140H, LYS146E, LYS146H, LYS230E, LYS230H, LYS252E, LYS252H, LYS253E, LYS253H, LYS458E, LYS458H, LYS478E, LYS478H, MET244E, MET244H, MET439E, MET439H, PHE233E, PHE414H, PHE454E, PHE454H, PRO134E, PRO134H, PRO136E, PRO136H, PRO148E, PRO148H, PRO226E, PRO226H, PRO249E, PRO249H, PRO453E, PRO453H, SER116E, SER116H, SER224E, SER236E, SER247E, SER247H, SER448E, SER448H, SER460E, SER460H, SER467E, SER467H, THR132E, THR132H, THR135E, THR135H, THR237E, THR237H, THR250E, THR250H, THR412E, THR412H, THR444E, THR444H, TRP120E, TRP120H, TRP429E, TRP429H, TRP63E, TRP63H, TYR113E, TYR419E, TYR419H, TYR421E, TYR421H, TYR437E, TYR437H, TYR469E, TYR469H, TYR479E, TYR479H, VAL128E, VAL143E, VAL143H, VAL144E, VAL144H, VAL145E, VAL145H, VAL228E, VAL228H, VAL239E, VAL251E, VAL251H, VAL292E, VAL292H, VAL428E, VAL428H, VAL431E, VAL431H, VAL440E, VAL440H, VAL451E, VAL451H, VAL457E, VAL457H, VAL475E, VAL475H, VAL476E, VAL476H, VAL482E, VAL482H, VAL484E, VAL484H
• E-I: ALA274E, ASP271E, ASP273E, ASP90I, LYS108I, LYS310E, LYS6I
• E-J: ALA328E, ALA364E, ALA87J, ARG12J, ARG200J, ARG322E, ARG80J, ASN88J, ASP7J, ASP91J, GLU325E, GLU371E, GLY321E, GLY366E, GLY3J, HIS363E, LEU10J, LEU11J, LEU365E, LEU84J, LYS319E, LYS6J, MET5J, PHE196J, PRO8J, SER316E, SER326E, SER9J, VAL320E
• E-N: ALA306N, ALA308N, ALA312N, ALA313N, ALA354N, ALA400E, ARG302E, ARG398E, ARG398N, ARG407E, ARG427E, ARG430E, ASP268E, ASP269E, ASP305N, ASP309N, ASP424E, GLU301E, GLU371N, GLU402E, GLU403E, GLU404E, GLY353N, GLY359N, GLY377N, HIS300E, LEU356N, LEU375N, LEU396N, LYS310N, LYS317N, MET357N, PHE267E, PHE307N, PHE399E, PRO372N, SER316N, SER355N, SER401E, THR358N, THR376N, TYR304N, VAL303E, VAL315N, VAL374N
• F-G: ALA129F, ALA129G, ALA238F, ALA238G, ALA245F, ALA245G, ALA248F, ALA248G, ALA274F, ALA274G, ALA281F, ALA281G, ALA417F, ALA417G, ALA418F, ALA418G, ALA432F, ALA432G, ALA434F, ALA434G, ALA452F, ALA452G, ALA483F, ALA483G, ARG141F, ARG141G, ARG229F, ARG229G, ARG241F, ARG241G, ARG285F, ARG423F, ARG423G, ARG430F, ARG430G, ARG464F, ARG464G, ARG67F, ARG67G, ASN139F, ASN139G, ASN225F, ASN410F, ASN410G, ASN443F, ASN443G, ASN449F, ASN449G, ASP131F, ASP131G, ASP137F, ASP137G, ASP472F, ASP472G, ASP473F, ASP473G, CYS481F, CYS481G, GLN246F, GLN246G, GLN459F, GLN459G, GLU147F, GLU147G, GLU257F, GLU257G, GLU413F, GLU413G, GLU433F, GLU433G, GLU436F, GLU436G, GLU450F, GLU450G, GLU465F, GLU465G, GLY130F, GLY130G, GLY150F, GLY150G, GLY240F, GLY240G, GLY259F, GLY259G, GLY278F, GLY415G, GLY438F, GLY438G, GLY441F, GLY441G, GLY445F, GLY445G, GLY455F, GLY455G, GLY456F, GLY456G, GLY461F, GLY461G, GLY463F, GLY463G, GLY466G, HIS468F, HIS468G, ILE142F, ILE142G, ILE149F, ILE149G, ILE227F, ILE425F, ILE442F, ILE442G, ILE447F, ILE447G, ILE477F, ILE477G, LEU133F, LEU133G, LEU231F, LEU231G, LEU242F, LEU242G, LEU243F, LEU243G, LEU254F, LEU254G, LEU256F, LEU256G, LEU258F, LEU258G, LEU416F, LEU416G, LEU420F, LEU420G, LEU435F, LEU435G, LEU446F, LEU446G, LEU462F, LEU462G, LEU480F, LEU480G, LYS140F, LYS140G, LYS146F, LYS146G, LYS230F, LYS230G, LYS252F, LYS252G, LYS253F, LYS253G, LYS458F, LYS458G, LYS478F, LYS478G, MET244F, MET244G, MET439F, MET439G, PHE414F, PHE454F, PHE454G, PRO134F, PRO134G, PRO136F, PRO136G, PRO148F, PRO148G, PRO226F, PRO226G, PRO249F, PRO249G, PRO453F, PRO453G, SER116F, SER116G, SER236G, SER247F, SER247G, SER448F, SER448G, SER460F, SER460G, SER467F, SER467G, THR132F, THR132G, THR135F, THR135G, THR237F, THR237G, THR250F, THR250G, THR412F, THR412G, THR444F, THR444G, TRP120F, TRP120G, TRP429F, TRP429G, TRP63F, TRP63G, TYR113F, TYR419F, TYR419G, TYR421F, TYR421G, TYR437F, TYR437G, TYR469F, TYR469G, TYR479F, TYR479G, VAL128G, VAL143F, VAL143G, VAL144F, VAL144G, VAL145F, VAL145G, VAL228F, VAL228G, VAL239G, VAL251F, VAL251G, VAL292F, VAL292G, VAL428F, VAL428G, VAL431F, VAL431G, VAL440F, VAL440G, VAL451F, VAL451G, VAL457F, VAL457G, VAL475F, VAL475G, VAL476F, VAL476G, VAL482F, VAL482G, VAL484F, VAL484G
• F-H: ALA129F, ALA129H, ALA138F, ALA138H, ALA174F, ALA174H, ALA175F, ALA71F, ALA71H, ARG127F, ARG127H, ARG141F, ARG141H, ARG423F, ARG423H, ARG427F, ARG427H, ARG430F, ARG430H, ARG67F, ARG67H, ARG74F, ARG74H, ASN139F, ASN139H, ASN443F, ASN443H, ASP131F, ASP131H, ASP137F, ASP137H, ASP269F, ASP269H, ASP424F, ASP424H, GLU123F, GLU123H, GLU124F, GLU124H, GLU73F, GLU73H, GLY125F, GLY125H, GLY130F, GLY130H, GLY426F, GLY426H, ILE142F, ILE142H, ILE425F, ILE425H, ILE442F, ILE442H, ILE471F, ILE471H, LEU133F, LEU133H, LEU420F, LEU420H, LEU480F, LEU480H, LYS126F, LYS126H, LYS140F, LYS140H, LYS146F, LYS146H, LYS478F, LYS478H, LYS69F, LYS69H, LYS72F, LYS72H, MET68F, MET68H, PRO134F, PRO134H, PRO136F, PRO136H, SER422F, SER422H, THR132F, THR132H, THR135F, THR135H, THR70F, THR70H, TRP429F, TRP429H, TYR421F, TYR421H, VAL128F, VAL128H, VAL143F, VAL143H, VAL144F, VAL144H, VAL145F, VAL145H, VAL428F, VAL428H, VAL475F, VAL475H
• G-H: ALA112G, ALA112H, ALA115G, ALA115H, ALA122G, ALA122H, ALA129G, ALA129H, ALA483G, ALA483H, ALA71G, ALA71H, ALA75G, ALA75H, ALA76G, ALA76H, ARG127G, ARG127H, ARG141G, ARG141H, ARG427G, ARG427H, ARG430G, ARG430H, ARG79G, ARG79H, ASN449G, ASN449H, ASP131H, ASP424H, ASP83G, ASP83H, GLU119G, GLU119H, GLU123G, GLU123H, GLU124G, GLU124H, GLU433G, GLU433H, GLU450G, GLU450H, GLY125G, GLY125H, GLY130G, GLY130H, GLY426G, GLY426H, HIS468G, HIS468H, ILE142G, ILE142H, ILE425G, ILE425H, ILE86G, ILE86H, LEU133G, LEU133H, LEU480G, LEU480H, LYS126G, LYS126H, LYS140G, LYS140H, LYS72G, LYS72H, PHE117G, PHE117H, PHE121G, PHE121H, PHE82G, PHE82H, SER116G, SER116H, SER467G, SER467H, THR132G, THR132H, THR70G, THR70H, TRP120G, TRP120H, TRP429G, TRP429H, TYR113G, TYR113H, TYR469G, VAL128G, VAL128H, VAL143G, VAL143H, VAL428G, VAL431G, VAL431H, VAL451G, VAL451H, VAL482G, VAL482H, VAL484G, VAL484H
• G-I: ALA328I, ALA364I, ALA36I, ALA400G, ARG302G, ARG322I, ARG398G, ARG407G, ARG430G, ASP268G, ASP305G, ASP34I, GLU301G, GLU325I, GLU39I, GLU402G, GLU403G, GLU404G, GLY321I, GLY323I, GLY366I, GLY38I, HIS300G, HIS363I, HIS367I, LEU365I, LEU41I, PHE369I, PHE399G, SER326I, SER401G, SER40I, SER4I, THR324I, THR37I, VAL320I
• G-M: LYS317G, MET68M
• G-N: ALA274G, ALA274N, ARG423N, ASP271G, ASP271N, ASP273G, ASP273N, LYS310G, LYS310N
• G-P: ARG302P, ARG427P, ASP268P, ASP305G, ASP309G, ASP424P, GLU402P, HIS300P
• H-N: LYS319N, MET68H
• I-J: ALA112I, ALA112J, ALA115I, ALA115J, ALA122I, ALA122J, ALA129I, ALA129J, ALA483I, ALA483J, ALA71I, ALA71J, ALA75I, ALA75J, ALA76I, ALA76J, ARG127I, ARG127J, ARG141I, ARG141J, ARG427I, ARG427J, ARG430I, ARG430J, ARG79I, ARG79J, ASN449I, ASN449J, ASP83I, ASP83J, GLU119I, GLU119J, GLU123I, GLU123J, GLU124I, GLU124J, GLU433I, GLU433J, GLU450I, GLU450J, GLY125I, GLY125J, GLY130I, GLY130J, GLY426I, GLY426J, HIS468I, HIS468J, ILE142I, ILE142J, ILE425I, ILE425J, ILE471I, ILE86I, LEU133I, LEU133J, LEU480I, LEU480J, LYS126I, LYS126J, LYS140I, LYS140J, LYS72I, LYS72J, PHE117I, PHE117J, PHE121I, PHE121J, PHE82I, PHE82J, SER116I, SER116J, SER467I, SER467J, THR132I, THR132J, THR135I, THR70I, TRP120I, TRP120J, TRP429I, TRP429J, TYR113I, TYR113J, TYR469I, TYR469J, VAL128I, VAL143I, VAL143J, VAL428J, VAL431I, VAL431J, VAL451I, VAL451J, VAL482I, VAL482J, VAL484I, VAL484J
• I-K: ALA129I, ALA129K, ALA138I, ALA138K, ALA174I, ALA71I, ALA71K, ARG127I, ARG127K, ARG141I, ARG141K, ARG423I, ARG423K, ARG427I, ARG427K, ARG430I, ARG430K, ARG67I, ARG74I, ARG74K, ASN139I, ASN139K, ASN443I, ASN443K, ASP131I, ASP131K, ASP137I, ASP137K, ASP269I, ASP269K, ASP424I, ASP424K, GLU123I, GLU123K, GLU124I, GLU124K, GLU73I, GLU73K, GLY125I, GLY125K, GLY130I, GLY130K, GLY426I, GLY426K, ILE142I, ILE142K, ILE425I, ILE425K, ILE442I, ILE442K, LEU133I, LEU133K, LEU420K, LEU480I, LEU480K, LYS126I, LYS126K, LYS140I, LYS140K, LYS146I, LYS146K, LYS478I, LYS478K, LYS69I, LYS69K, LYS72I, LYS72K, MET68I, MET68K, PRO134I, PRO134K, PRO136I, PRO136K, SER422I, SER422K, THR132I, THR132K, THR135I, THR135K, THR70I, THR70K, TRP429I, TRP429K, TYR421I, TYR421K, VAL128I, VAL128K, VAL143I, VAL143K, VAL144I, VAL144K, VAL145I, VAL145K, VAL428I, VAL428K, VAL475I, VAL475K, VAL482I
• I-L: ALA129I, ALA129L, ALA238I, ALA238L, ALA245I, ALA245L, ALA248I, ALA248L, ALA274I, ALA274L, ALA281I, ALA281L, ALA417I, ALA417L, ALA418I, ALA418L, ALA432I, ALA432L, ALA434I, ALA434L, ALA452I, ALA452L, ALA483I, ALA483L, ARG141I, ARG141L, ARG229I, ARG229L, ARG241I, ARG241L, ARG423I, ARG423L, ARG430I, ARG430L, ARG464I, ARG464L, ARG67I, ARG67L, ASN139I, ASN139L, ASN410I, ASN410L, ASN443I, ASN443L, ASN449I, ASN449L, ASP131I, ASP131L, ASP137I, ASP137L, ASP472I, ASP472L, CYS481I, CYS481L, GLN246I, GLN246L, GLN459I, GLN459L, GLN60I, GLU147I, GLU147L, GLU413I, GLU413L, GLU433I, GLU433L, GLU436I, GLU436L, GLU450I, GLU450L, GLU465L, GLY130I, GLY130L, GLY150I, GLY150L, GLY240I, GLY240L, GLY278L, GLY415L, GLY438I, GLY438L, GLY441I, GLY441L, GLY445I, GLY445L, GLY455I, GLY455L, GLY456I, GLY456L, GLY461I, GLY461L, GLY463I, GLY463L, HIS468I, HIS468L, ILE142I, ILE142L, ILE149I, ILE149L, ILE227L, ILE425I, ILE425L, ILE442I, ILE442L, ILE447I, ILE447L, ILE477I, ILE477L, LEU133I, LEU133L, LEU231L, LEU242I, LEU242L, LEU243I, LEU243L, LEU254I, LEU254L, LEU256I, LEU256L, LEU258I, LEU258L, LEU416I, LEU416L, LEU420I, LEU420L, LEU435I, LEU435L, LEU446I, LEU446L, LEU462I, LEU462L, LEU480I, LEU480L, LYS140I, LYS140L, LYS146I, LYS146L, LYS230I, LYS230L, LYS252I, LYS252L, LYS253I, LYS253L, LYS458I, LYS458L, LYS478I, LYS478L, MET244I, MET244L, MET439I, MET439L, PHE233I, PHE414I, PHE414L, PHE454I, PHE454L, PRO134I, PRO134L, PRO136I, PRO136L, PRO148I, PRO148L, PRO226I, PRO226L, PRO249I, PRO249L, PRO453I, PRO453L, SER116I, SER116L, SER236L, SER247I, SER247L, SER422I, SER448I, SER448L, SER460I, SER460L, SER467I, SER467L, THR132I, THR132L, THR135I, THR135L, THR237I, THR237L, THR250I, THR250L, THR412I, THR412L, THR444I, THR444L, TRP120I, TRP120L, TRP429I, TRP429L, TRP63I, TRP63L, TYR113I, TYR419I, TYR419L, TYR421I, TYR421L, TYR437I, TYR437L, TYR469I, TYR469L, TYR479I, TYR479L, VAL143I, VAL143L, VAL144I, VAL144L, VAL145I, VAL145L, VAL228I, VAL228L, VAL239L, VAL251I, VAL251L, VAL292I, VAL292L, VAL428I, VAL428L, VAL431I, VAL431L, VAL440I, VAL440L, VAL451I, VAL451L, VAL457I, VAL457L, VAL475I, VAL475L, VAL476I, VAL476L, VAL482I, VAL482L, VAL484I, VAL484L
• I-N: ARG302N, GLY327I, LEU318I, LYS317I, LYS319I, SER316I, THR329I
• I-P: ARG362I, ASP305P, ASP309P, GLU343I
• J-K: ALA129J, ALA129K, ALA238J, ALA238K, ALA245J, ALA245K, ALA248J, ALA248K, ALA274J, ALA274K, ALA281J, ALA281K, ALA417J, ALA417K, ALA418J, ALA418K, ALA432J, ALA432K, ALA434J, ALA434K, ALA452J, ALA452K, ALA483J, ALA483K, ARG141J, ARG141K, ARG229J, ARG229K, ARG241J, ARG241K, ARG285J, ARG423J, ARG423K, ARG430J, ARG430K, ARG464J, ARG464K, ARG67J, ARG67K, ASN139J, ASN139K, ASN410J, ASN410K, ASN443J, ASN443K, ASN449J, ASN449K, ASP131J, ASP131K, ASP137J, ASP137K, ASP472J, ASP472K, ASP473J, ASP473K, CYS481J, CYS481K, GLN246J, GLN246K, GLN459J, GLN459K, GLN60J, GLN60K, GLU147J, GLU147K, GLU257J, GLU257K, GLU413J, GLU413K, GLU433J, GLU433K, GLU436J, GLU436K, GLU450J, GLU450K, GLU465J, GLU465K, GLY130J, GLY130K, GLY150J, GLY150K, GLY240J, GLY240K, GLY259J, GLY259K, GLY278J, GLY278K, GLY415K, GLY438J, GLY438K, GLY441J, GLY441K, GLY445J, GLY445K, GLY455J, GLY455K, GLY456J, GLY456K, GLY461J, GLY461K, GLY463J, GLY463K, GLY466K, GLY470K, HIS468J, HIS468K, ILE142J, ILE142K, ILE149J, ILE149K, ILE227J, ILE425J, ILE425K, ILE442J, ILE442K, ILE447J, ILE447K, ILE477J, ILE477K, LEU133J, LEU133K, LEU231J, LEU242J, LEU242K, LEU243J, LEU243K, LEU254J, LEU254K, LEU256J, LEU256K, LEU258J, LEU258K, LEU416J, LEU416K, LEU420J, LEU420K, LEU435J, LEU435K, LEU446J, LEU446K, LEU462J, LEU462K, LEU480J, LEU480K, LYS140J, LYS140K, LYS146J, LYS146K, LYS230J, LYS230K, LYS252J, LYS252K, LYS253J, LYS253K, LYS458J, LYS458K, LYS478J, LYS478K, MET244J, MET244K, MET439J, MET439K, PHE233J, PHE233K, PHE414J, PHE454J, PHE454K, PRO134J, PRO134K, PRO136J, PRO136K, PRO148J, PRO148K, PRO226J, PRO226K, PRO249J, PRO249K, PRO453J, PRO453K, SER116J, SER116K, SER247J, SER247K, SER448J, SER448K, SER460J, SER460K, SER467J, SER467K, THR132J, THR132K, THR135J, THR135K, THR237J, THR237K, THR250J, THR250K, THR412J, THR412K, THR444J, THR444K, TRP120J, TRP120K, TRP429J, TRP429K, TRP63J, TRP63K, TYR113K, TYR419J, TYR419K, TYR421J, TYR421K, TYR437J, TYR437K, TYR469J, TYR469K, TYR479J, TYR479K, VAL143J, VAL143K, VAL144J, VAL144K, VAL145J, VAL145K, VAL228J, VAL228K, VAL239K, VAL251J, VAL251K, VAL292J, VAL292K, VAL428J, VAL428K, VAL431J, VAL431K, VAL440J, VAL440K, VAL451J, VAL451K, VAL457J, VAL457K, VAL475J, VAL475K, VAL476J, VAL476K, VAL482J, VAL482K, VAL484J, VAL484K
• J-L: ALA129J, ALA129L, ALA138J, ALA138L, ALA432L, ALA71J, ALA71L, ARG127J, ARG127L, ARG141J, ARG141L, ARG423J, ARG423L, ARG427J, ARG427L, ARG430J, ARG430L, ARG67J, ARG67L, ARG74J, ARG74L, ASN139J, ASN139L, ASN443J, ASN443L, ASP131J, ASP131L, ASP137J, ASP137L, ASP269J, ASP269L, ASP271J, ASP424J, ASP424L, GLU123J, GLU123L, GLU124J, GLU124L, GLU73J, GLU73L, GLY125J, GLY125L, GLY130J, GLY130L, GLY426J, GLY426L, ILE142J, ILE142L, ILE425J, ILE425L, ILE442J, ILE442L, LEU133J, LEU133L, LEU420J, LEU420L, LEU480J, LEU480L, LYS126J, LYS126L, LYS140J, LYS140L, LYS146J, LYS146L, LYS478J, LYS478L, LYS69J, LYS69L, LYS72J, LYS72L, MET68J, MET68L, PRO134J, PRO134L, PRO136J, PRO136L, SER422J, SER422L, THR132J, THR132L, THR135J, THR135L, THR70J, THR70L, TRP429J, TRP429L, TYR421J, TYR421L, VAL128J, VAL128L, VAL143J, VAL143L, VAL144J, VAL144L, VAL145J, VAL145L, VAL428J, VAL428L, VAL475J, VAL475L
• K-L: ALA112K, ALA112L, ALA115K, ALA115L, ALA122K, ALA122L, ALA129K, ALA129L, ALA483K, ALA483L, ALA71K, ALA71L, ALA75K, ALA75L, ALA76K, ALA76L, ARG127K, ARG127L, ARG141K, ARG141L, ARG427K, ARG427L, ARG430K, ARG430L, ARG79K, ARG79L, ASN449K, ASN449L, ASP83K, ASP83L, GLU119K, GLU119L, GLU123K, GLU123L, GLU124K, GLU124L, GLU433K, GLU433L, GLU450K, GLU450L, GLY125K, GLY125L, GLY130K, GLY130L, GLY426K, GLY426L, HIS468K, HIS468L, ILE142K, ILE142L, ILE425K, ILE425L, ILE86K, LEU133K, LEU133L, LEU480K, LEU480L, LYS126K, LYS126L, LYS140K, LYS140L, LYS72K, LYS72L, PHE117K, PHE117L, PHE121K, PHE121L, PHE82K, PHE82L, SER116K, SER116L, SER467K, SER467L, THR132K, THR132L, THR135K, THR70K, THR70L, TRP120K, TRP120L, TRP429K, TRP429L, TYR113K, TYR113L, TYR469K, VAL128K, VAL128L, VAL143K, VAL143L, VAL428K, VAL431K, VAL431L, VAL451K, VAL451L, VAL482K, VAL482L, VAL484K, VAL484L
• M-N: ALA112M, ALA112N, ALA115M, ALA115N, ALA122M, ALA122N, ALA129M, ALA129N, ALA483M, ALA483N, ALA71M, ALA71N, ALA75M, ALA75N, ALA76M, ALA76N, ARG127M, ARG127N, ARG141M, ARG141N, ARG427M, ARG427N, ARG430M, ARG430N, ARG79M, ARG79N, ASN449M, ASN449N, ASP83M, ASP83N, GLU119M, GLU119N, GLU123M, GLU123N, GLU124M, GLU124N, GLU433M, GLU433N, GLU450M, GLU450N, GLY125M, GLY125N, GLY130M, GLY130N, GLY426M, GLY426N, HIS468M, HIS468N, ILE142M, ILE142N, ILE425M, ILE425N, ILE471N, ILE86M, ILE86N, LEU133M, LEU133N, LEU480M, LEU480N, LYS126M, LYS126N, LYS140M, LYS140N, LYS72M, LYS72N, PHE117M, PHE117N, PHE121M, PHE121N, PHE82M, PHE82N, SER116M, SER116N, SER467M, SER467N, THR132M, THR132N, THR135M, THR135N, THR70M, THR70N, TRP120M, TRP120N, TRP429M, TRP429N, TYR113M, TYR113N, TYR469M, TYR469N, VAL128M, VAL128N, VAL143M, VAL143N, VAL431N, VAL451M, VAL451N, VAL482M, VAL482N, VAL484M, VAL484N
• M-O: ARG423M, ARG423O, ARG427M, ARG427O, ASP131M, ASP131O, ASP137M, ASP269M, ASP269O, ASP424M, ASP424O, GLY130M, GLY130O, ILE425M, ILE425O, LYS72O, THR132M, THR132O, VAL144M
• M-P: ALA432M, ALA432P, ALA483M, ALA483P, ARG229M, ARG229P, ARG241M, ARG241P, ASP131M, ASP131P, ASP472M, ASP472P, CYS481M, CYS481P, GLN459M, GLN459P, GLU147M, GLU147P, GLU433M, GLU433P, GLU436M, GLU436P, GLY438M, GLY438P, HIS468M, HIS468P, ILE442M, ILE442P, ILE447M, LEU435M, LEU435P, LEU446P, LYS140M, LYS458M, LYS458P, LYS478M, LYS478P, PRO249M, PRO249P, THR250M, THR250P, THR444P, TYR479M, TYR479P, VAL440M, VAL440P
• N-O: ALA432N, ALA432O, ALA483N, ALA483O, ARG229N, ARG229O, ARG241N, ARG241O, ASN449N, ASP131N, ASP131O, ASP472N, ASP472O, CYS481N, CYS481O, GLN459N, GLN459O, GLU147N, GLU147O, GLU433N, GLU433O, GLU436N, GLU436O, GLY438N, GLY438O, HIS468N, HIS468O, ILE442N, ILE442O, LEU435N, LEU435O, LEU446N, LEU446O, LYS140N, LYS140O, LYS458N, LYS458O, LYS478N, LYS478O, PRO249N, PRO249O, THR250N, THR250O, TYR479N, TYR479O, VAL440N, VAL440O
• N-P: ARG423N, ARG423P, ARG427N, ARG427P, ASP131N, ASP131P, ASP137N, ASP269N, ASP269P, ASP424N, ASP424P, GLY130N, GLY130P, ILE425N, ILE425P, LYS72P, THR132N, THR132P, VAL144N
• O-P: ARG127O, ARG127P, ARG141O, ARG141P, ARG79O, ARG79P, GLU119O, GLU119P, GLU123O, GLU123P, GLU124O, GLU124P, GLU433O, GLU433P, GLU450O, GLU450P, HIS468O, HIS468P, LYS126O, LYS126P, LYS72O, LYS72P, TRP120O, TRP120P