3I6U

structure and activation mechanism of the chk2 dna-damage checkpoint kinase

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 258
  • Norm. En. per Res.: -1.9751
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-50.2462	-25.0189	-434.302	-509.5671	258	19	11	21673	5	79	78

Interface residues

• A-B: ALA158A, ALA158B, ALA230A, ALA230B, ALA237A, ALA237B, ALA247A, ALA247B, ALA257A, ALA257B, ALA91A, ALA91B, ALA94A, ALA94B, ALA98A, ALA98B, ARG148A, ARG180A, ARG180B, ARG181A, ARG181B, ARG240A, ARG240B, ARG254A, ARG254B, ARG346A, ARG346B, ARG431A, ARG95A, ARG95B, ASN105A, ASN105B, ASN154A, ASN154B, ASN171A, ASN171B, ASN184A, ASN184B, ASN185A, ASN185B, ASN186A, ASN186B, ASN269A, ASN269B, ASN316A, ASN316B, ASN405A, ASP203A, ASP203B, ASP207A, ASP207B, ASP208A, ASP208B, ASP311A, ASP311B, CYS231A, CYS231B, CYS243A, CYS243B, CYS420B, GLN209A, GLN209B, GLN358A, GLN358B, GLU107A, GLU107B, GLU149A, GLU149B, GLU173A, GLU173B, GLU188A, GLU188B, GLU233A, GLU233B, GLU239A, GLU239B, GLU271B, GLU273B, GLU305A, GLU305B, GLU308A, GLU308B, GLU351A, GLU351B, GLU429A, GLU429B, GLY151A, GLY151B, GLY227A, GLY227B, GLY229A, GLY229B, GLY232A, GLY232B, GLY259A, GLY259B, GLY306A, GLY306B, GLY307A, GLY307B, GLY315A, GLY315B, GLY376A, GLY423A, GLY423B, HIS430A, ILE157A, ILE157B, ILE160A, ILE160B, ILE221A, ILE221B, ILE258A, ILE258B, ILE416A, ILE416B, ILE419A, ILE419B, LEU174A, LEU183A, LEU183B, LEU204A, LEU204B, LEU226A, LEU226B, LEU236A, LEU236B, LEU268A, LEU268B, LEU303A, LEU303B, LEU309A, LEU309B, LEU354A, LEU375A, LEU396B, LEU436B, LEU96A, LEU96B, LEU99A, LEU99B, LYS153A, LYS153B, LYS179A, LYS179B, LYS197A, LYS197B, LYS224A, LYS224B, LYS235B, LYS241A, LYS241B, LYS244A, LYS244B, LYS245A, LYS245B, LYS253A, LYS253B, LYS255A, LYS255B, LYS312B, LYS317A, LYS317B, LYS349A, LYS349B, LYS373A, LYS437B, MET222A, MET222B, MET304A, MET304B, PHE147A, PHE147B, PHE199A, PHE199B, PHE201A, PHE201B, PHE202A, PHE202B, PHE238A, PHE238B, PHE256A, PHE256B, PHE310A, PHE310B, PHE427A, PHE427B, PRO152A, PRO152B, PRO182A, PRO182B, PRO350A, PRO350B, PRO388A, PRO388B, PRO425A, PRO425B, PRO426A, PRO426B, PRO92A, PRO92B, SER155A, SER155B, SER187A, SER187B, SER223A, SER223B, SER228A, SER228B, SER252A, SER252B, SER422B, SER428A, SER428B, THR205A, THR205B, THR225A, THR225B, THR242A, THR242B, THR272B, THR389A, THR389B, TRP93A, TRP93B, TRP97A, TRP97B, TYR156A, TYR156B, TYR159A, TYR159B, TYR212B, TYR390A, TYR390B, TYR424A, TYR424B, VAL150A, VAL150B, VAL170A, VAL170B, VAL175A, VAL175B, VAL200A, VAL200B, VAL206A, VAL206B, VAL234A, VAL234B, VAL246A, VAL313A, VAL313B, VAL314A, VAL314B, VAL395A, VAL397A, VAL397B, VAL415A, VAL415B