3HZR

tryptophanyl-trna synthetase homolog from entamoeba histolytica

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 129
  • Norm. En. per Res.: -4.186
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-90.3758	15.5548	-427.374	-502.195	126	25	20	17192	0	32	20
A-C	-2.478	-8.8825	-22.3803	-33.7408	41	8	0	1671	0	13	14
A-D	0.0	0.0	-90.7976	-90.7976	57	4	0	4536	0	1	6
A-F	0.0	-6.6108	-20.7534	-27.3642	38	4	0	1572	0	13	14
B-D	0.0	-6.3712	-29.5453	-35.9165	39	4	0	1570	0	13	13
B-E	-3.2881	-2.4351	-21.9887	-27.7119	36	4	0	1335	0	10	13
B-F	0.0	0.0	-99.1701	-99.1701	58	3	0	4650	0	0	6
C-D	-87.0156	5.8563	-458.836	-539.9953	129	32	21	18184	0	31	21
C-E	0.0	0.8264	-20.294	-19.4676	28	0	5	1534	0	4	16
E-F	-35.5538	5.9072	-403.329	-432.9756	127	21	20	16969	0	30	23

Interface residues

• A-B: ALA127A, ALA127B, ALA132A, ALA132B, ALA175A, ALA175B, ALA177A, ALA177B, ALA197A, ALA197B, ARG125A, ARG125B, ARG167A, ARG167B, ASN124A, ASN124B, ASN130A, ASN130B, ASN179A, ASN179B, ASN192A, ASN192B, ASP118A, ASP118B, ASP119A, ASP119B, ASP158A, ASP158B, ASP191A, ASP191B, GLN160A, GLN160B, GLN182A, GLN182B, GLU126A, GLU126B, GLU131A, GLU131B, GLU173A, GLU173B, GLU188A, GLU188B, GLY163A, GLY163B, GLY194A, GLY194B, ILE120A, ILE120B, ILE129A, ILE129B, ILE169A, ILE169B, ILE193A, ILE193B, ILE201A, ILE201B, ILE235A, ILE235B, ILE239A, ILE239B, LEU123A, LEU123B, LEU171A, LEU171B, LEU196A, LEU196B, LYS121A, LYS121B, LYS164A, LYS164B, LYS174A, LYS174B, LYS195A, LYS195B, MET165A, MET165B, PHE162A, PHE162B, PHE185A, PHE185B, PHE187A, PHE187B, PHE232A, PHE232B, PRO183A, PRO183B, PRO199A, PRO199B, SER133A, SER133B, SER170A, SER170B, SER190A, SER190B, SER198A, SER198B, SER200A, SER200B, THR128A, THR128B, THR157A, THR157B, THR168A, THR168B, THR176A, THR176B, THR203A, THR203B, TYR159A, TYR159B, TYR161A, TYR161B, TYR166A, TYR166B, TYR178A, TYR178B, TYR189A, TYR189B, VAL122A, VAL122B, VAL172A, VAL172B, VAL180A, VAL180B, VAL181A, VAL181B
• A-C: ALA219A, ALA74A, ARG125C, ASN109A, ASN130C, ASN137C, ASN149A, ASP151A, GLN111A, GLU131C, GLU150A, HIS213A, ILE110A, ILE129C, LYS134C, LYS152A, LYS164A, LYS373C, LYS378A, LYS380A, LYS75A, LYS76A, LYS88C, PHE154A, PHE214A, PHE215A, PHE381A, PRO77A, SER133C, SER212A, SER216A, SER217A, SER377A, THR128C, THR153A, THR369C, THR379A, THR78A, TYR159C, TYR211A, VAL122C
• A-D: ALA175D, ALA219A, ALA219D, ALA240A, ALA240D, ALA74A, ALA74D, ARG167A, ARG167D, ARG220A, ARG220D, ASN244A, ASN244D, ASP71A, ASP71D, CYS221A, GLN209A, GLN209D, GLN238A, GLN238D, ILE239A, ILE239D, ILE246A, ILE246D, LEU171A, LEU171D, LEU243A, LEU243D, LYS174A, LYS174D, LYS75A, LYS75D, LYS76A, LYS76D, PHE215A, PHE215D, PHE245A, PHE245D, PRO218A, PRO218D, PRO77A, PRO77D, SER208A, SER208D, SER216A, SER216D, SER217A, SER217D, THR168A, THR168D, THR241A, THR241D, THR242A, THR242D, THR78A, THR78D, VAL172D
• A-F: ALA219F, ALA74F, ARG125A, ASN109F, ASN130A, ASN137A, ASN149F, ASP151F, GLN111F, GLU131A, GLU150F, HIS213F, ILE110F, ILE129A, LYS134A, LYS152F, LYS164F, LYS373A, LYS378F, LYS380F, LYS75F, LYS76F, LYS88A, PHE154F, PHE214F, PHE215F, PHE381F, PRO77F, SER133A, SER212F, SER216F, SER217F, THR128A, THR369A, THR379F, THR78F, TYR211F, VAL122A
• B-D: ALA132B, ALA219D, ALA74D, ARG125B, ASN109D, ASN130B, ASN137B, ASN149D, ASP151D, GLN111D, GLU131B, GLU150D, HIS213D, ILE110D, ILE129B, LYS134B, LYS152D, LYS164D, LYS373B, LYS378D, LYS380D, LYS75D, LYS76D, LYS88B, PHE154D, PHE214D, PHE215D, PHE381D, PRO77D, SER133B, SER212D, SER216D, SER217D, THR128B, THR369B, THR379D, THR78D, TYR211D, VAL122B
• B-E: ALA74B, ARG125E, ASN109B, ASN130E, ASN137E, ASN149B, ASP151B, GLN111B, GLU131E, GLU150B, HIS213B, ILE129E, LYS134E, LYS152B, LYS164B, LYS373E, LYS378B, LYS380B, LYS75B, LYS76B, LYS88E, PHE154B, PHE214B, PHE215B, PHE381B, PRO77B, SER133E, SER212B, SER216B, SER217B, THR128E, THR369E, THR379B, THR78B, TYR211B, VAL122E
• B-F: ALA175B, ALA175F, ALA219B, ALA219F, ALA240B, ALA240F, ALA74B, ALA74F, ARG167B, ARG167F, ARG220B, ARG220F, ASN244B, ASN244F, ASP71B, ASP71F, CYS221B, CYS221F, GLN209B, GLN209F, GLN238B, GLN238F, ILE239B, ILE239F, ILE246B, ILE246F, LEU171B, LEU171F, LEU243B, LEU243F, LYS174B, LYS174F, LYS75B, LYS75F, LYS76B, LYS76F, PHE215B, PHE215F, PHE245B, PHE245F, PRO218B, PRO218F, PRO77B, PRO77F, SER208B, SER208F, SER216B, SER216F, SER217B, SER217F, THR168B, THR168F, THR241B, THR241F, THR242B, THR242F, THR78B, THR78F
• C-D: ALA127C, ALA127D, ALA132C, ALA132D, ALA175C, ALA175D, ALA177C, ALA177D, ALA197C, ALA197D, ARG125C, ARG125D, ARG167C, ARG167D, ASN124C, ASN124D, ASN130C, ASN130D, ASN179C, ASN179D, ASN192C, ASN192D, ASP118C, ASP118D, ASP119C, ASP119D, ASP158C, ASP158D, ASP191C, ASP191D, GLN160C, GLN160D, GLN182C, GLN182D, GLU126C, GLU126D, GLU131C, GLU131D, GLU173C, GLU173D, GLU188C, GLU188D, GLY163C, GLY163D, GLY194C, GLY194D, ILE120C, ILE120D, ILE129C, ILE129D, ILE169C, ILE169D, ILE193C, ILE193D, ILE201C, ILE201D, ILE235C, ILE235D, ILE239C, ILE239D, LEU123C, LEU123D, LEU171C, LEU171D, LEU196C, LEU196D, LYS121C, LYS121D, LYS164C, LYS164D, LYS174C, LYS174D, LYS195C, LYS195D, MET165C, MET165D, MET202C, PHE162C, PHE162D, PHE185C, PHE185D, PHE187C, PHE187D, PHE232C, PHE232D, PHE245C, PRO183C, PRO183D, PRO199C, PRO199D, SER133C, SER133D, SER170C, SER170D, SER190C, SER190D, SER198C, SER198D, SER200C, SER200D, THR128C, THR128D, THR157C, THR157D, THR168C, THR168D, THR176C, THR176D, THR203C, THR203D, THR242C, TYR159C, TYR159D, TYR161C, TYR161D, TYR166C, TYR166D, TYR178C, TYR178D, TYR189C, TYR189D, VAL122C, VAL122D, VAL172C, VAL172D, VAL180C, VAL180D, VAL181C, VAL181D
• C-E: ALA370C, ALA370E, ALA374C, ALA374E, ASP151C, ASP151E, ILE367C, ILE367E, ILE376C, ILE376E, LEU372C, LEU372E, LYS373C, LYS373E, LYS378C, LYS378E, PRO366C, PRO366E, SER377C, SER377E, THR368C, THR368E, THR369C, THR369E, TYR371C, TYR371E, TYR375C, TYR375E
• E-F: ALA127E, ALA127F, ALA132E, ALA132F, ALA175E, ALA175F, ALA177E, ALA177F, ALA197E, ALA197F, ARG125E, ARG125F, ARG167E, ARG167F, ASN124E, ASN124F, ASN130E, ASN130F, ASN179E, ASN179F, ASN192E, ASN192F, ASP118E, ASP118F, ASP119E, ASP119F, ASP158E, ASP158F, ASP191E, ASP191F, GLN160E, GLN160F, GLN182E, GLN182F, GLU126E, GLU126F, GLU131E, GLU131F, GLU173E, GLU173F, GLU188E, GLU188F, GLY163E, GLY163F, GLY194E, GLY194F, ILE120E, ILE120F, ILE129E, ILE129F, ILE169E, ILE169F, ILE193E, ILE193F, ILE201E, ILE201F, ILE235F, ILE239E, ILE239F, LEU123E, LEU123F, LEU171E, LEU171F, LEU196E, LEU196F, LEU243E, LYS121E, LYS121F, LYS164E, LYS164F, LYS174E, LYS174F, LYS195E, LYS195F, MET165E, MET165F, PHE162E, PHE162F, PHE185E, PHE185F, PHE187E, PHE187F, PHE232E, PHE232F, PHE245E, PRO183E, PRO183F, PRO199E, PRO199F, SER133E, SER133F, SER170E, SER170F, SER190E, SER190F, SER198E, SER198F, SER200E, SER200F, THR128E, THR128F, THR157E, THR157F, THR168E, THR168F, THR176E, THR176F, THR203E, THR203F, TYR159E, TYR159F, TYR161E, TYR161F, TYR166E, TYR166F, TYR178E, TYR178F, TYR189E, TYR189F, VAL122E, VAL122F, VAL172E, VAL172F, VAL180E, VAL180F, VAL181E, VAL181F