3HUX

structure of ef-p bound to the 70s ribosome; this file contains the 50s subunit for molecule i.

• Total interactions analyzed: 496
• Total true interactions: 30
• Strongest Interaction:
  • Chains: R-W
  • Int. Res.: 19
  • Norm. En. per Res.: -3.6828
• Hub Node: E(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
C-G	0.0	26.7932	-52.7682	-25.975	34	15	2	2728	0	26	23
C-6	0.0	3.6757	-9.3955	-5.7198	35	0	0	1031	0	9	12
E-N	0.0	0.0	-39.5139	-39.5139	14	3	0	1364	0	0	2
E-O	-6.2514	3.2456	-32.5423	-35.5481	16	2	0	1108	0	9	10
E-R	0.0	0.0	-5.2723	-5.2723	12	0	0	351	0	1	8
E-T	-7.5847	-6.9187	-123.251	-137.7544	72	17	5	6495	0	20	18
F-P	-5.8919	28.5936	-82.7202	-60.0185	43	9	0	4740	0	18	23
F-U	0.0	0.0	-1.2173	-1.2173	10	0	0	284	0	0	2
F-7	0.0	0.0	-0.0016	-0.0016	2	0	0	1	0	0	0
G-4	-32.9339	-2.3953	-105.555	-140.8842	63	15	4	5881	0	13	10
I-1	0.0	0.0	-31.5289	-31.5289	36	4	1	2107	0	7	10
N-U	-14.7695	-0.2073	-132.214	-147.1907	50	11	1	5930	0	9	26
N-V	0.0	3.1564	-11.514	-8.3575	15	4	0	800	0	1	5
O-T	-47.1935	14.0356	-240.93	-274.0879	78	26	5	10323	3	42	42
P-U	0.0	0.0	-0.0155	-0.0155	5	0	0	17	0	0	1
P-V	0.0	9.3312	-6.6298	2.7014	12	0	0	529	0	0	6
P-8	-11.7177	14.3443	-188.554	-185.9275	58	31	0	8672	2	17	61
Q-Z	-3.9029	-65.3007	-171.2	-240.4036	98	31	3	9014	3	56	51
Q-0	0.0	0.0	-6.7406	-6.7406	10	0	0	423	0	0	4
Q-9	0.0	0.0	-0.1672	-0.1672	5	0	0	58	0	1	3
R-W	-13.8932	-37.4599	-18.6202	-69.9733	19	4	0	945	2	6	9
R-5	-8.765	2.0159	-52.6665	-59.4155	36	2	4	2963	0	6	14
S-0	0.0	-5.9297	-3.3819	-9.3115	19	0	0	267	0	8	12
U-V	-3.0969	-17.6368	-220.161	-240.8946	91	33	11	10418	0	16	34
U-5	0.0	1.5	-8.6174	-7.1174	13	0	0	653	0	0	9
W-5	-3.4816	38.0403	-102.837	-68.2783	49	7	3	4868	1	12	21
X-2	-19.5487	-13.2613	-120.315	-153.125	48	6	3	4922	2	10	14
X-7	0.0	0.0	-0.6921	-0.6921	7	4	0	184	0	2	6
0-8	0.0	0.0	-0.038	-0.038	2	0	0	21	0	2	1
6-8	-6.7499	0.0	-21.8363	-28.5862	17	3	0	1148	0	3	1

Interface residues

• C-G: ALA123C, ALA46G, ALA50G, ALA79C, ARG51G, ARG72G, ASP119C, ASP49G, GLU48G, GLU54G, GLU82C, GLU88C, GLU98C, GLU99C, GLY81C, GLY96C, GLY97C, ILE100C, ILE52G, ILE78C, ILE84C, LEU53G, LEU82G, LYS47G, LYS55G, LYS80C, LYS83C, LYS85C, MET86G, PRO87G, THR117C, VAL120C, VAL70G, VAL95C
• C-6: ALA143C, ALA196C, ALA199C, ARG161C, ARG195C, ARG286, ARG506, ARG60C, ASN140C, ASN149C, ASN296, ASN326, GLU152C, GLU156C, GLY144C, GLY147C, GLY61C, HIS200C, ILE153C, LEU346, LYS142C, LYS176, LYS336, PHE148C, PRO141C, PRO316, PRO66C, SER64C, THR145C, THR146, THR306, THR62C, VAL146C, VAL526, VAL63C
• E-N: ARG149E, GLY153E, GLY77N, GLY80N, GLY81N, LYS152E, LYS154E, PRO147E, PRO79N, SER76N, TYR151E, TYR75N, TYR78N, VAL150E
• E-O: ALA20E, ARG13E, ARG16E, ARG19E, ARG71O, ASP17E, ASP18E, ASP73O, GLY74O, ILE14E, LYS70O, PHE15E, PRO22E, PRO72O, SER75O, VAL21E
• E-R: ALA114E, ARG111E, GLY110E, GLY112E, HIS3R, LEU4R, LYS109E, LYS118E, LYS5R, PHE113E, PRO191E, TYR160E
• E-T: ALA20E, ALA5T, ARG13E, ARG13T, ARG16E, ARG19E, ARG39T, ARG3T, ARG53T, ARG76E, ASN180E, ASN192E, ASN2T, ASN55T, ASN58T, ASP174E, ASP17E, ASP18E, GLN54E, GLU11T, GLU178E, GLU179E, GLY10E, GLY193E, GLY29E, GLY4T, HIS79T, ILE14E, ILE176E, ILE26E, ILE75T, ILE7T, LEU181E, LEU182E, LEU183E, LEU27E, LEU52E, LEU6T, LEU78T, LEU82T, LEU9T, LYS33T, LYS8E, LYS8T, MET11E, MET1T, PHE15E, PHE51E, PHE57T, PHE76T, PRO30E, PRO53E, PRO77T, PRO81T, SER12T, SER80T, THR12E, THR24E, THR40T, THR59T, THR60T, TYR14T, TYR32T, VAL10T, VAL15T, VAL173E, VAL21E, VAL23E, VAL25E, VAL34T, VAL7E, VAL9E
• F-P: ALA113F, ALA12P, ARG117F, ARG119F, ARG15P, ARG16P, ARG188F, ARG18P, ARG38F, ARG44F, ARG7P, ARG95F, ASN13P, ASN29F, ASN9P, ASP116F, ASP185F, ASP5P, GLN40F, GLU120F, GLU190F, GLU35F, GLY11P, HIS31F, ILE186F, ILE28F, LEU32F, LEU33F, LEU41F, LEU6P, LYS122F, LYS14P, LYS17P, PRO10P, PRO30F, PRO8P, THR189F, TRP34F, TYR184F, VAL183F, VAL187F, VAL36F, VAL37F
• F-U: ALA49F, ALA4U, ARG3U, ARG45F, GLY91F, PRO2U, PRO92F, THR51F, TYR97F, VAL88F
• F-7: ALA58F, LYS377
• G-4: ALA110G, ALA384, ALA61G, ALA6G, ARG113G, ARG394, ARG98G, ARG9G, ASN108G, ASN464, ASP116G, ASP4G, ASP97G, CYS424, CYS624, CYS654, GLU104G, GLU143G, GLU494, GLU564, GLU604, GLY65G, ILE101G, ILE114G, ILE140G, ILE144G, ILE404, ILE414, ILE484, ILE574, ILE63G, LEU107G, LEU111G, LEU3G, LEU62G, LEU7G, LYS105G, LYS544, LYS644, LYS8G, MET148G, PHE102G, PHE117G, PHE141G, PRO112G, PRO142G, PRO179G, PRO2G, PRO374, SER524, SER634, THR145G, THR504, THR534, THR64G, TRP100G, TYR514, TYR584, VAL109G, VAL364, VAL594, VAL5G, VAL614
• I-1: ALA26I, ALA36I, ALA641, ARG27I, ARG33I, ARG501, ARG521, ARG761, ASN28I, ASN43I, GLU721, GLU751, GLY24I, GLY34I, HIS661, ILE671, LEU31I, LEU38I, LEU6I, LYS481, LYS691, LYS781, MET1I, PRO23I, PRO32I, PRO681, SER42I, SER651, THR40I, TYR29I, TYR711, VAL37I, VAL491, VAL511, VAL701, VAL741
• N-U: ALA67U, ALA68U, ALA96U, ALA99U, ARG101U, ARG12N, ARG35N, ARG39N, ARG59U, ARG64U, ARG70U, ARG92U, ASN45N, ASN66U, ASN94U, ASP41N, ASP56U, ASP97U, CYS69U, GLN71U, GLY36N, HIS38N, HIS72U, ILE62U, ILE65U, LEU60U, LEU95U, LEU98U, LYS29N, LYS2N, LYS37N, LYS93U, MET1N, MET48N, PHE106U, PHE57U, PRO103U, PRO40N, PRO44N, PRO6N, THR32N, THR3N, THR43N, TRP42N, TRP61U, TYR4N, VAL100U, VAL46N, VAL5N, VAL63U
• N-V: ALA3V, ARG13V, GLN11V, GLU15V, ILE4V, LEU18V, LEU20V, LYS10V, LYS19V, LYS2N, MET1N, PHE2V, TYR12V, VAL14V, VAL5V
• O-T: ALA103O, ALA118O, ALA11O, ALA76O, ALA83O, ARG103T, ARG104O, ARG107O, ARG41T, ARG51T, ARG64O, ARG64T, ARG71O, ARG74T, ARG78O, ASN38T, ASN82O, ASP44T, ASP73O, ASP80O, ASP81O, GLN43T, GLU105O, GLU108O, GLU120O, GLU36T, GLU46T, GLU68O, GLU73T, GLU9O, GLY100O, GLY37T, GLY69T, GLY71T, GLY74O, HIS79T, ILE50T, ILE69O, ILE75T, ILE77O, LEU122O, LEU78T, LYS33T, LYS35T, LYS65T, LYS66O, LYS70O, MET112O, PHE45T, PHE61T, PHE76T, PHE79O, PHE99O, PRO101O, PRO119O, PRO72O, PRO77T, PRO81T, SER106T, SER31T, SER67T, SER75O, SER80T, THR60T, THR62T, THR65O, TYR100T, TYR32T, TYR68T, VAL102O, VAL115O, VAL121O, VAL34T, VAL63O, VAL63T, VAL66T, VAL70T, VAL72T
• P-U: ARG36U, GLY26P, LYS13U, PHE40U, SER25P
• P-V: ALA31P, ARG82V, ARG83V, GLN80V, GLY26P, GLY28P, HIS27P, SER25P, THR30P, THR32P, TYR81V, VAL79V
• P-8: ALA108, ALA248, ALA558, ARG138, ARG308, ARG468, ARG49P, ARG50P, ARG55P, ARG578, ARG61P, ARG65P, ASP47P, GLN68P, GLU548, GLU568, GLY288, GLY458, GLY66P, GLY69P, GLY98, HIS78, ILE168, ILE588, LEU508, LEU59P, LEU608, LEU618, LEU62P, LYS118, LYS128, LYS158, LYS268, LYS298, LYS448, LYS478, LYS528, LYS58, LYS598, LYS64P, LYS88, MET258, MET48, MET60P, MET67P, PHE51P, PRO48P, PRO538, PRO63P, THR178, THR278, THR57P, THR58P, THR68, VAL148, VAL228, VAL238, VAL498
• Q-Z: ALA107Q, ALA112Z, ALA136Q, ALA172Z, ALA20Q, ALA28Q, ALA36Q, ARG101Q, ARG111Z, ARG121Z, ARG133Q, ARG134Q, ARG48Z, ARG51Q, ARG56Q, ARG59Q, ARG60Q, ARG71Z, ARG78Z, ARG79Z, ARG80Z, ARG81Z, ASN74Z, ASP122Z, ASP135Q, ASP138Q, ASP178Z, ASP25Q, ASP31Q, ASP44Z, ASP76Z, GLN117Z, GLN72Z, GLU118Z, GLU177Z, GLU180Z, GLU38Q, GLU48Q, GLY100Q, GLY108Q, GLY113Z, GLY114Z, GLY19Q, GLY23Q, GLY24Q, GLY30Q, GLY33Q, GLY61Q, GLY62Q, HIS120Z, HIS53Z, ILE119Z, ILE131Q, ILE52Z, ILE64Q, ILE66Q, LEU116Z, LEU37Q, LEU75Z, LYS130Q, LYS181Z, LYS18Q, LYS22Q, LYS63Q, LYS77Z, LYS98Q, MET54Q, PHE103Z, PHE29Q, PHE43Z, PHE47Z, PHE58Q, PHE65Q, PRO100Z, PRO175Z, PRO176Z, PRO39Q, PRO82Z, PRO99Q, SER51Z, THR21Q, TYR137Q, TYR26Q, TYR98Z, VAL102Q, VAL106Q, VAL109Q, VAL110Z, VAL115Z, VAL132Q, VAL173Z, VAL174Z, VAL179Z, VAL27Q, VAL35Q, VAL52Q, VAL55Q, VAL73Z
• Q-0: ARG100, ARG10Q, ASN110, GLY84Q, GLY86Q, LYS11Q, LYS85Q, LYS87Q, SER80, THR90
• Q-9: ARG119Q, GLU116Q, HIS123Q, LYS89, SER69
• R-W: ALA101R, ALA109R, ARG103R, ARG104R, ARG105R, ARG37W, ARG42W, ASN40W, ASP107R, GLU102R, GLY106R, GLY108R, LEU100R, LEU36W, LYS41W, PRO110R, THR39W, TYR38W, TYR45W
• R-5: ALA101R, ALA112R, ALA535, ARG103R, ARG33R, ARG555, ARG96R, CYS465, GLU102R, GLU115R, GLU485, GLY505, GLY545, HIS435, ILE34R, LEU100R, LEU111R, LEU113R, LEU305, LEU98R, LYS405, LYS565, LYS99R, MET395, PRO110R, PRO415, PRO425, PRO475, THR445, TYR515, TYR525, VAL114R, VAL38R, VAL455, VAL575, VAL97R
• S-0: ARG15S, ARG23S, ARG710, ASN490, GLN690, GLU43S, GLY470, GLY510, HIS790, ILE18S, LEU610, LEU740, LYS480, PRO460, PRO820, THR21S, TYR770, VAL500, VAL620
• U-V: ALA107U, ALA113U, ALA3V, ALA41U, ALA42U, ALA46U, ALA48U, ALA77V, ALA86U, ALA96U, ARG101U, ARG112U, ARG13V, ARG36U, ARG50U, ARG53U, ARG82V, ARG83V, ARG92U, ASN44U, ASN94U, ASP91U, ASP97U, GLN104U, GLN11V, GLN80V, GLU102U, GLU108U, GLU15V, GLU37U, GLU43V, GLU89U, GLY41V, GLY42V, GLY43U, GLY48V, GLY87U, GLY9V, HIS87V, ILE17U, ILE4V, ILE70V, ILE88U, LEU109U, LEU20U, LEU38V, LEU39U, LEU39V, LEU40V, LEU71V, LEU83U, LEU95U, LEU98U, LYS10V, LYS16U, LYS44V, LYS51U, LYS54U, LYS6V, LYS74V, LYS76V, LYS84V, LYS85U, LYS85V, LYS93U, MET1V, PHE106U, PHE2V, PHE40U, PHE75V, PRO103U, PRO50V, SER73V, THR45V, THR49V, THR7V, TRP61U, TYR12V, TYR45U, TYR47U, TYR81V, VAL100U, VAL105U, VAL14V, VAL46V, VAL47V, VAL51V, VAL52V, VAL5V, VAL72V, VAL90U
• U-5: ALA145, ARG155, ARG28U, GLY26U, LEU27U, LYS105, LYS135, LYS30U, SER125, SER29U, SER31U, THR115, TRP25U
• W-5: ALA245, ALA25, ALA385, ALA44W, ALA89W, ARG15W, ARG165, ARG18W, ARG195, ARG205, ARG33W, ARG37W, ARG90W, ARG92W, ASN34W, ASN40W, ASP22W, CYS465, GLU30W, GLU31W, GLU485, HIS225, HIS235, ILE24W, ILE35W, LEU19W, LEU23W, LEU255, LEU305, LEU36W, LYS16W, LYS27W, LYS35, LYS405, LYS41W, MET395, PRO275, PRO285, PRO415, PRO475, THR265, THR295, THR39W, THR445, TYR38W, VAL17W, VAL20W, VAL21W, VAL455
• X-2: ALA10X, ALA392, ALA42X, ALA46X, ALA4X, ALA91X, ARG262, ARG302, ARG362, ASP6X, GLN382, GLU272, GLU312, GLU342, GLY422, GLY94X, HIS31X, ILE412, ILE572, ILE89X, ILE8X, LEU13X, LEU322, LEU612, LEU92X, LEU9X, LYS282, LYS292, LYS2X, LYS48X, MET332, PHE28X, PHE372, PHE47X, PRO11X, SER402, THR27X, THR3X, THR45X, TRP29X, TYR18X, TYR26X, TYR5X, VAL12X, VAL252, VAL30X, VAL43X, VAL7X
• X-7: ARG477, ARG60X, ARG97, LEU70X, LYS487, LYS63X, TRP407
• 0-8: ARG540, LYS398
• 6-8: ALA226, ASN266, ASN338, GLN358, GLU126, GLU246, ILE418, LEU106, LEU116, LEU328, LEU96, LYS256, LYS276, LYS368, LYS86, THR236, TRP348