3HR5

m1prime peptide from ige bound by humanized antibody 47h4 fab

• Total interactions analyzed: 66
• Total true interactions: 30
• Strongest Interaction:
  • Chains: J-V
  • Int. Res.: 35
  • Norm. En. per Res.: -7.5132
• Hub Node: H(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-21.9138	-43.4631	217.249	151.8721	203	14	13	19490	2	28	20
L-J	-12.6431	0.0	-40.2476	-52.8907	33	1	0	1770	0	0	0
L-R	-41.8909	3.8404	-97.9031	-135.9536	28	5	2	3135	0	0	3
H-B	-30.4523	0.7064	-138.804	-168.5499	62	7	0	4929	0	4	7
H-P	-15.8336	-17.0334	-112.362	-145.229	67	4	1	5039	0	7	9
H-Q	0.0	0.0	-9.5971	-9.5971	22	0	0	841	0	5	6
H-J	0.0	0.0	-7.4618	-7.4618	16	0	0	734	0	1	2
H-R	-24.9066	-71.0935	-149.588	-245.5881	35	5	0	4311	5	9	5
A-B	-15.3673	-45.0704	-495.324	-555.7618	198	5	13	18776	3	29	18
A-I	-2.3466	0.0	-24.6687	-27.0153	33	0	0	1382	0	0	0
A-S	-58.8653	4.6232	-129.037	-183.279	33	13	2	4510	0	0	3
B-P	0.0	0.0	-9.9559	-9.9559	22	0	0	737	0	4	6
B-I	0.0	0.0	-7.4717	-7.4717	16	0	0	515	0	1	2
B-Q	-22.7306	-20.5965	-120.537	-163.8641	69	6	1	5240	1	7	9
B-S	-25.0283	-62.7344	-140.753	-228.5156	38	12	0	4319	4	9	5
P-I	-40.8878	-47.2445	182.743	94.6107	205	14	14	19269	4	28	19
P-J	0.0	0.0	-0.0015	-0.0015	2	0	0	1	0	1	0
P-R	0.0	0.0	-0.0954	-0.0954	8	0	0	29	0	2	3
P-T	-32.0106	4.0513	-100.141	-128.1003	27	3	2	3203	0	0	3
I-J	0.0	11.0607	-0.231	10.8297	3	0	0	22	0	0	5
I-S	0.0	0.0	-6.1013	-6.1013	2	0	0	338	0	1	1
I-T	-36.4408	-65.6003	-137.815	-239.856	35	9	0	4274	5	9	5
I-V	-10.0491	-28.1177	-9.9987	-48.1655	13	1	0	522	2	2	1
Q-J	-12.8764	-38.2725	196.203	145.0541	202	14	12	19296	1	29	20
Q-S	0.0	0.0	-0.3846	-0.3846	12	0	0	71	0	2	3
Q-V	-58.1476	3.8369	-102.897	-157.2076	27	8	2	3180	0	0	3
J-R	0.0	0.0	-5.1265	-5.1265	2	0	0	268	1	1	1
J-T	-9.6212	-38.6264	-13.971	-62.2186	12	2	0	653	3	2	1
J-V	-36.6657	-89.0309	-137.265	-262.9616	35	12	0	4225	6	10	4
T-V	0.0	15.3502	-7.0274	8.3228	5	0	0	278	0	2	1

Interface residues

• L-H: ALA103H, ALA129H, ALA135L, ALA140H, ALA141H, ALA172H, ALA35H, ALA48L, ALA49H, ALA61H, ALA97H, ARG147L, ARG216L, ARG38H, ARG98H, ASN100H, ASN142L, ASN143L, ASN215L, ASN33L, ASN35L, ASN58L, ASN96L, ASP102H, ASP105H, ASP127L, ASP148H, ASP172L, ASP175L, ASP1L, ASP62H, ASP99H, CYS139L, CYS144H, CYS219L, CYS220H, CYS93L, CYS96H, GLN105L, GLN109H, GLN129L, GLN165L, GLN175H, GLN39H, GLN42L, GLN43L, GLN95L, GLU128L, GLU166L, GLU170L, GLU218L, GLU46H, GLU6H, GLY104L, GLY106L, GLY108H, GLY110H, GLY137H, GLY138H, GLY143H, GLY162L, GLY166H, GLY178H, GLY217L, GLY33H, GLY42H, GLY44H, GLY46L, GLY62L, HIS168H, HIS31L, HIS39L, ILE122L, ILE34H, ILE51H, ILE53L, ILE58H, LEU128H, LEU130L, LEU140L, LEU141L, LEU142H, LEU145H, LEU174H, LEU179H, LEU180L, LEU182H, LEU184L, LEU186L, LEU38L, LEU45H, LEU51L, LEU52L, LEU98L, LYS108L, LYS131L, LYS133H, LYS147H, LYS174L, LYS212L, LYS213H, LYS214H, LYS218H, LYS43H, LYS44L, LYS47L, LYS50L, LYS55L, MET104H, PHE103L, PHE121L, PHE123L, PHE126H, PHE144L, PHE170H, PHE214L, PHE50H, PHE60L, PRO100L, PRO124L, PRO125L, PRO127H, PRO130H, PRO171H, PRO45L, PRO49L, SER119L, SER124H, SER126L, SER131H, SER132H, SER132L, SER134H, SER136L, SER164L, SER165H, SER167L, SER176H, SER177H, SER179L, SER181H, SER181L, SER182L, SER183H, SER184H, SER190H, SER213L, SER219H, SER52H, SER61L, SER94L, THR102L, THR134L, THR139H, THR169H, THR169L, THR177L, THR183L, THR185L, THR187H, THR36L, THR57H, THR63H, THR90L, THR97L, TRP101H, TRP101L, TRP107H, TRP36H, TRP40L, TRP47H, TYR106H, TYR178L, TYR180H, TYR191L, TYR197L, TYR37L, TYR41L, TYR54L, TYR59H, TYR60H, TYR91L, TYR92L, TYR95H, VAL120L, VAL125H, VAL137L, VAL138L, VAL146H, VAL167H, VAL168L, VAL173H, VAL185H, VAL186H, VAL188H, VAL196L, VAL215H, VAL2H, VAL37H, VAL48H, VAL56L, VAL93H, VAL99L
• L-J: ALA162J, ARG59L, ARG66L, ASN159J, GLN196J, GLN84L, GLU86L, GLY137J, GLY138J, GLY161J, GLY194J, GLY62L, LEU163J, LEU193J, LYS174L, PHE60L, PHE67L, PRO189J, PRO64L, PRO85L, SER190J, SER191J, SER192J, SER61L, SER65L, SER81L, SER82L, THR164J, THR195J, THR197J, TYR198J, VAL188J, VAL63L
• L-R: ALA12R, ALA34L, ALA7R, ARG11R, ASN32L, ASN33L, ASN35L, ASN96L, ASP1L, GLN10R, GLN27L, GLN8R, GLN95L, HIS31L, HIS39L, ILE2L, LEU29L, LEU98L, LYS55L, PRO100L, SER28L, SER9R, THR97L, TRP101L, TYR37L, TYR54L, VAL30L, VAL99L
• H-B: ALA118B, ALA118H, ARG19B, ARG19H, ASN203B, ASN203H, ASN208B, ASN208H, ASP73B, ASP73H, GLN13B, GLN13H, GLY122B, GLY122H, GLY15B, HIS204B, HIS204H, LEU11B, LEU11H, LYS121B, LYS121H, LYS205B, LYS205H, LYS210B, LYS210H, LYS76B, LYS76H, PHE150B, PHE150H, PRO123B, PRO123H, PRO14B, PRO14H, PRO151B, PRO151H, PRO206B, PRO206H, SER116B, SER116H, SER117B, SER117H, SER119B, SER119H, SER124H, SER207B, SER207H, THR114B, THR114H, THR120B, THR120H, THR209B, THR209H, TYR80B, TYR80H, VAL115B, VAL115H, VAL12B, VAL12H, VAL202B, VAL202H, VAL211B, VAL211H
• H-P: ALA34P, ALA55H, ARG18P, ARG19H, ARG59P, ARG66P, ARG67H, ARG72H, ASN35P, ASN58P, ASN74H, ASN84H, ASP17P, ASP53H, ASP73H, ASP75P, GLN82H, GLN84P, GLY16P, GLY66H, GLY69P, GLY71P, GLY73P, ILE51H, ILE58H, ILE70H, ILE80P, LEU18H, LEU54H, LEU81H, LEU83P, LYS55P, LYS76H, MET83H, PHE50H, PHE67P, PHE68H, PHE76P, SER17H, SER52H, SER57P, SER65P, SER68P, SER70P, SER71H, SER72P, SER75H, SER81P, SER82P, SER85H, THR20P, THR36P, THR57H, THR65H, THR69H, THR77P, THR79P, TYR54P, TYR56H, TYR59H, TYR60H, TYR80H, VAL15P, VAL19P, VAL30P, VAL56P, VAL64H
• H-Q: ARG59Q, ASN74H, ASN77H, ASP172Q, GLN3H, GLU1H, GLU86Q, GLY62Q, LYS174Q, LYS50Q, LYS76H, PRO64Q, PRO85Q, SER160H, SER173Q, SER25H, SER61Q, SER65Q, SER75H, THR114Q, VAL2H, VAL63Q
• H-J: ALA162J, ASP31H, GLU1H, GLU1J, GLY166J, GLY26H, HIS168J, LEU163J, LEU54H, SER165J, SER30H, THR164J, THR28H, TYR106H, VAL167J, VAL2H
• H-R: ALA103H, ALA12R, ALA35H, ALA55H, ALA7R, ARG11R, ARG15R, ARG72H, ASN100H, ASN74H, ASP102H, ASP14R, ASP31H, ASP53H, ASP99H, GLN10R, GLN8R, GLY33H, ILE51H, ILE58H, LEU54H, MET104H, PHE29H, PHE50H, PRO13R, SER30H, SER52H, SER9R, THR28H, THR57H, TRP101H, TRP47H, TYR32H, TYR56H, TYR59H
• A-B: ALA103B, ALA129B, ALA135A, ALA140B, ALA141B, ALA172B, ALA35B, ALA48A, ALA49B, ALA61B, ALA97B, ARG38B, ARG98B, ASN100B, ASN142A, ASN143A, ASN163A, ASN215A, ASN33A, ASN35A, ASN58A, ASN96A, ASP102B, ASP105B, ASP127A, ASP148B, ASP172A, ASP175A, ASP1A, ASP62B, ASP99B, CYS139A, CYS144B, CYS219A, CYS220B, CYS93A, CYS96B, GLN105A, GLN109B, GLN129A, GLN165A, GLN175B, GLN39B, GLN42A, GLN43A, GLN95A, GLU128A, GLU166A, GLU170A, GLU218A, GLU46B, GLU6B, GLY104A, GLY106A, GLY108B, GLY110B, GLY133A, GLY138B, GLY143B, GLY162A, GLY166B, GLY178B, GLY217A, GLY33B, GLY42B, GLY44B, GLY46A, GLY62A, HIS168B, HIS31A, HIS39A, ILE122A, ILE34B, ILE51B, ILE53A, ILE58B, LEU128B, LEU130A, LEU140A, LEU141A, LEU142B, LEU145B, LEU174B, LEU179B, LEU180A, LEU182B, LEU184A, LEU186A, LEU38A, LEU45B, LEU51A, LEU52A, LEU98A, LYS131A, LYS133B, LYS147B, LYS174A, LYS212A, LYS213B, LYS214B, LYS218B, LYS43B, LYS44A, LYS47A, LYS50A, LYS55A, MET104B, PHE103A, PHE121A, PHE123A, PHE126B, PHE144A, PHE170B, PHE214A, PHE50B, PHE60A, PRO100A, PRO124A, PRO125A, PRO127B, PRO130B, PRO171B, PRO45A, PRO49A, SER119A, SER124B, SER126A, SER131B, SER132A, SER132B, SER136A, SER164A, SER165B, SER167A, SER176B, SER177B, SER179A, SER181A, SER181B, SER182A, SER183B, SER184B, SER190B, SER213A, SER219B, SER52B, SER61A, SER94A, THR102A, THR134A, THR139B, THR169A, THR169B, THR177A, THR183A, THR185A, THR187B, THR36A, THR57B, THR63B, THR90A, THR97A, TRP101A, TRP101B, TRP107B, TRP36B, TRP40A, TRP47B, TYR106B, TYR178A, TYR180B, TYR191A, TYR37A, TYR41A, TYR54A, TYR59B, TYR60B, TYR91A, TYR92A, TYR95B, VAL120A, VAL125B, VAL137A, VAL138A, VAL146B, VAL167B, VAL168A, VAL173B, VAL185B, VAL186B, VAL188B, VAL215B, VAL2B, VAL37B, VAL48B, VAL56A, VAL93B, VAL99A
• A-I: ALA162I, ARG59A, ARG66A, ASN159I, GLN196I, GLN84A, GLU86A, GLY137I, GLY138I, GLY161I, GLY194I, GLY62A, LEU163I, LEU193I, LYS174A, LYS50A, PHE60A, PHE67A, PRO189I, PRO64A, PRO85A, SER160I, SER165I, SER191I, SER192I, SER61A, SER65A, SER82A, THR164I, THR195I, THR197I, TYR198I, VAL63A
• A-S: ALA12S, ALA34A, ALA7S, ARG11S, ASN32A, ASN33A, ASN35A, ASN96A, ASP1A, GLN10S, GLN27A, GLN3A, GLN8S, GLN95A, HIS31A, HIS39A, ILE2A, LEU29A, LEU98A, LYS55A, PRO100A, SER26A, SER28A, SER6S, SER9S, THR102A, THR36A, THR97A, TRP101A, TYR37A, TYR41A, VAL30A, VAL99A
• B-P: ARG59P, ASN74B, ASN77B, ASP73B, GLN3B, GLU1B, GLU86P, GLY62P, LYS174P, LYS50P, LYS76B, PHE60P, PRO64P, PRO85P, SER173P, SER25B, SER61P, SER65P, SER75B, THR78B, VAL2B, VAL63P
• B-I: ALA162I, ASP31B, GLU1B, GLU1I, GLY161I, LEU163I, LEU54B, SER165I, SER30B, SER75B, THR164I, THR28B, TYR106B, TYR106I, VAL167I, VAL2B
• B-Q: ALA34Q, ALA55B, ARG18Q, ARG19B, ARG59Q, ARG66Q, ARG67B, ARG72B, ASN35Q, ASN58Q, ASN74B, ASN84B, ASP17Q, ASP53B, ASP73B, ASP75Q, GLN82B, GLN84Q, GLY16Q, GLY66B, GLY69Q, GLY71Q, GLY73Q, ILE51B, ILE53Q, ILE58B, ILE70B, ILE80Q, LEU18B, LEU54B, LEU81B, LEU83Q, LYS55Q, LYS76B, MET83B, PHE67Q, PHE68B, PHE76Q, PRO64Q, SER17B, SER52B, SER57Q, SER65Q, SER68Q, SER70Q, SER71B, SER72Q, SER75B, SER81Q, SER82Q, SER85B, THR20Q, THR36Q, THR57B, THR65B, THR69B, THR77Q, THR78B, THR79Q, TYR37Q, TYR54Q, TYR56B, TYR60B, TYR80B, VAL15Q, VAL19Q, VAL30Q, VAL56Q, VAL64B
• B-S: ALA103B, ALA12S, ALA35B, ALA55B, ALA7S, ARG11S, ARG15S, ARG72B, ASN100B, ASN74B, ASP102B, ASP14S, ASP31B, ASP53B, ASP62B, ASP99B, GLN10S, GLN8S, GLY33B, ILE51B, ILE58B, LEU54B, MET104B, PHE29B, PHE50B, PRO13S, SER30B, SER52B, SER6S, SER9S, THR28B, THR57B, TRP101B, TRP47B, TYR32B, TYR56B, TYR59B, VAL16S
• P-I: ALA103I, ALA129I, ALA135P, ALA140I, ALA141I, ALA172I, ALA35I, ALA48P, ALA49I, ALA61I, ALA97I, ARG147P, ARG216P, ARG38I, ARG98I, ASN100I, ASN142P, ASN143P, ASN163P, ASN215P, ASN33P, ASN35P, ASN58P, ASN96P, ASP102I, ASP105I, ASP127P, ASP148I, ASP172P, ASP175P, ASP1P, ASP62I, ASP99I, CYS139P, CYS144I, CYS219P, CYS220I, CYS93P, CYS96I, GLN105P, GLN109I, GLN129P, GLN165P, GLN171P, GLN175I, GLN39I, GLN42P, GLN43P, GLN95P, GLU128P, GLU166P, GLU170P, GLU218P, GLU46I, GLU6I, GLY104P, GLY106P, GLY108I, GLY110I, GLY137I, GLY138I, GLY143I, GLY162P, GLY166I, GLY178I, GLY217P, GLY33I, GLY42I, GLY44I, GLY46P, GLY62P, HIS168I, HIS31P, HIS39P, ILE122P, ILE34I, ILE51I, ILE53P, ILE58I, LEU128I, LEU130P, LEU140P, LEU141P, LEU142I, LEU145I, LEU174I, LEU179I, LEU180P, LEU182I, LEU184P, LEU186P, LEU38P, LEU45I, LEU51P, LEU52P, LEU98P, LYS108P, LYS131P, LYS133I, LYS147I, LYS174P, LYS212P, LYS213I, LYS214I, LYS218I, LYS43I, LYS44P, LYS47P, LYS50P, LYS55P, MET104I, PHE103P, PHE121P, PHE123P, PHE126I, PHE144P, PHE170I, PHE214P, PHE50I, PHE60P, PRO100P, PRO124P, PRO125P, PRO127I, PRO130I, PRO171I, PRO45P, PRO49P, SER119P, SER124I, SER126P, SER131I, SER132I, SER132P, SER134I, SER136P, SER164P, SER165I, SER167P, SER173P, SER176I, SER177I, SER179P, SER181I, SER181P, SER182P, SER183I, SER184I, SER190I, SER213P, SER219I, SER52I, SER61P, SER94P, THR102P, THR134P, THR139I, THR169I, THR169P, THR177P, THR183P, THR185P, THR187I, THR36P, THR57I, THR63I, THR90P, THR97P, TRP101I, TRP101P, TRP107I, TRP36I, TRP40P, TRP47I, TYR106I, TYR178P, TYR180I, TYR197P, TYR37P, TYR41P, TYR54P, TYR59I, TYR60I, TYR91P, TYR92P, TYR95I, VAL120P, VAL125I, VAL137P, VAL138P, VAL146I, VAL167I, VAL168P, VAL173I, VAL185I, VAL186I, VAL188I, VAL196P, VAL215I, VAL2I, VAL37I, VAL48I, VAL56P, VAL93I, VAL99P
• P-J: ASN35P, GLU1J
• P-R: ALA34P, ARG15R, ASP14R, GLN10R, GLY71P, SER57P, SER72P, THR36P
• P-T: ALA12T, ALA34P, ALA7T, ARG11T, ASN32P, ASN33P, ASN35P, ASN96P, ASP1P, GLN10T, GLN27P, GLN8T, GLN95P, HIS31P, HIS39P, ILE2P, LEU29P, LEU98P, LYS55P, PRO100P, SER28P, SER9T, THR97P, TRP101P, TYR37P, VAL30P, VAL99P
• I-J: ASP31I, ASP31J, TRP101J
• I-S: ARG15S, GLU1I
• I-T: ALA103I, ALA12T, ALA35I, ALA55I, ALA7T, ARG11T, ARG15T, ARG72I, ASN100I, ASP102I, ASP14T, ASP31I, ASP53I, ASP99I, GLN10T, GLN8T, GLY33I, ILE51I, ILE58I, LEU17T, LEU54I, MET104I, PHE50I, PRO13T, SER30I, SER52I, SER9T, THR28I, THR57I, TRP101I, TRP47I, TYR32I, TYR56I, TYR59I, VAL16T
• I-V: ALA12V, ARG15V, ASN74I, ASP31I, ASP53I, LEU54I, PHE29I, PRO13V, SER30I, SER75I, THR28I, TYR32I, VAL16V
• Q-J: ALA103J, ALA129J, ALA135Q, ALA140J, ALA141J, ALA172J, ALA35J, ALA48Q, ALA49J, ALA61J, ALA97J, ARG147Q, ARG216Q, ARG38J, ARG98J, ASN100J, ASN142Q, ASN143Q, ASN215Q, ASN33Q, ASN35Q, ASN58Q, ASN96Q, ASP102J, ASP105J, ASP127Q, ASP148J, ASP172Q, ASP175Q, ASP1Q, ASP62J, ASP99J, CYS139Q, CYS144J, CYS219Q, CYS220J, CYS93Q, CYS96J, GLN105Q, GLN109J, GLN129Q, GLN165Q, GLN171Q, GLN175J, GLN39J, GLN42Q, GLN43Q, GLN95Q, GLU128Q, GLU166Q, GLU170Q, GLU218Q, GLU46J, GLU6J, GLY104Q, GLY106Q, GLY108J, GLY110J, GLY133Q, GLY137J, GLY138J, GLY143J, GLY162Q, GLY166J, GLY217Q, GLY33J, GLY42J, GLY44J, GLY46Q, HIS168J, HIS31Q, HIS39Q, ILE122Q, ILE34J, ILE51J, ILE53Q, ILE58J, LEU128J, LEU130Q, LEU140Q, LEU141Q, LEU142J, LEU145J, LEU174J, LEU179J, LEU180Q, LEU182J, LEU184Q, LEU186Q, LEU38Q, LEU45J, LEU51Q, LEU52Q, LEU98Q, LYS131Q, LYS133J, LYS147J, LYS174Q, LYS212Q, LYS213J, LYS214J, LYS218J, LYS43J, LYS44Q, LYS47Q, LYS50Q, LYS55Q, MET104J, PHE103Q, PHE121Q, PHE123Q, PHE126J, PHE144Q, PHE170J, PHE214Q, PHE50J, PHE60Q, PRO100Q, PRO124Q, PRO125Q, PRO127J, PRO130J, PRO171J, PRO45Q, PRO49Q, SER119Q, SER124J, SER126Q, SER131J, SER132J, SER132Q, SER134J, SER136Q, SER164Q, SER165J, SER167Q, SER173Q, SER176J, SER177J, SER179Q, SER181J, SER181Q, SER182Q, SER183J, SER184J, SER190J, SER213Q, SER219J, SER52J, SER61Q, SER94Q, THR102Q, THR134Q, THR139J, THR169J, THR169Q, THR177Q, THR183Q, THR185Q, THR187J, THR36Q, THR57J, THR63J, THR90Q, THR97Q, TRP101J, TRP101Q, TRP107J, TRP36J, TRP40Q, TRP47J, TYR106J, TYR178Q, TYR180J, TYR191Q, TYR37Q, TYR41Q, TYR54Q, TYR59J, TYR60J, TYR91Q, TYR92Q, TYR95J, VAL120Q, VAL125J, VAL137Q, VAL138Q, VAL146J, VAL167J, VAL168Q, VAL173J, VAL185J, VAL186J, VAL188J, VAL196Q, VAL215J, VAL2J, VAL37J, VAL48J, VAL56Q, VAL93J, VAL99Q
• Q-S: ALA34Q, ARG15S, ASN35Q, ASN58Q, ASP14S, GLN10S, GLY71Q, LYS55Q, SER57Q, SER72Q, THR36Q, VAL16S
• Q-V: ALA12V, ALA34Q, ALA7V, ARG11V, ASN32Q, ASN33Q, ASN35Q, ASN96Q, ASP1Q, GLN10V, GLN27Q, GLN8V, GLN95Q, HIS31Q, HIS39Q, ILE2Q, LEU29Q, LEU98Q, LYS55Q, PRO100Q, SER28Q, SER9V, THR97Q, TRP101Q, TYR37Q, VAL30Q, VAL99Q
• J-R: ARG15R, GLU1J
• J-T: ALA12T, ARG15T, ASP31J, ASP53J, LEU17T, LEU54J, PHE29J, PRO13T, SER30J, THR28J, TYR32J, VAL16T
• J-V: ALA103J, ALA12V, ALA35J, ALA55J, ALA7V, ARG11V, ARG15V, ARG72J, ASN100J, ASN74J, ASP102J, ASP14V, ASP31J, ASP53J, ASP99J, GLN10V, GLN8V, GLY33J, ILE51J, LEU54J, MET104J, PHE29J, PHE50J, PRO13V, SER30J, SER52J, SER9V, THR28J, THR57J, TRP101J, TRP47J, TYR32J, TYR56J, TYR59J, VAL16V
• T-V: ARG15T, ARG15V, PRO13T, PRO13V, VAL16T