3HNA

crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with sah and mono- methylated h3k9 peptide

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-Q
  • Int. Res.: 66
  • Norm. En. per Res.: -6.946
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-94.856	7.2198	-365.057	-452.6932	128	15	5	13140	0	25	25
A-P	-56.9406	-107.2331	-199.998	-364.1717	63	7	3	7267	8	27	15
B-Q	-70.2064	-146.9518	-241.281	-458.4391	66	7	3	8174	10	36	16

Interface residues

• A-B: ALA1077A, ALA1077B, ALA1184A, ALA1184B, ALA957A, ALA963A, ALA984A, ALA984B, ARG1023A, ARG1023B, ARG1082A, ARG1082B, ARG1087A, ARG1087B, ARG1137A, ARG1137B, ARG981A, ARG981B, ARG985A, ARG985B, ASN1013A, ASN1013B, ASN1020A, ASN1020B, ASN1024A, ASN1024B, ASN1075A, ASN1075B, ASN1083A, ASN1083B, ASN951A, ASP1022A, ASP1022B, ASP1035B, ASP982A, ASP982B, CYS1014A, CYS1014B, CYS1031A, CYS1031B, CYS1033A, CYS1033B, CYS1074A, CYS1074B, CYS1078A, CYS1078B, CYS1080A, CYS1080B, CYS1084A, CYS1084B, GLN1012A, GLN1012B, GLN1029B, GLN1090A, GLN1090B, GLN959A, GLU1127A, GLU1127B, GLU988A, GLU988B, GLY949A, GLY986A, GLY986B, HIS1027A, HIS1027B, HIS1076A, HIS1076B, ILE1021A, ILE1021B, ILE1025A, ILE1025B, ILE1034B, ILE983A, ILE983B, ILE992A, ILE992B, LEU1028A, LEU1028B, LEU958A, LEU964A, LYS1008A, LYS1008B, LYS962A, MET1019A, MET1019B, MET1043B, MET960A, PHE1160A, PHE1160B, PRO1018A, PRO1018B, PRO991A, PRO991B, PRO993A, PRO993B, SER1011A, SER1011B, SER1017A, SER1017B, SER1079A, SER1079B, SER950A, SER952A, SER961A, SER980A, SER980B, THR1016A, THR1016B, THR1026A, THR1026B, TRP1081A, TRP1081B, TRP955A, TYR1009A, TYR1009B, TYR1030A, TYR1030B, TYR1161A, TYR1161B, TYR987A, TYR987B, VAL1010A, VAL1010B, VAL1015A, VAL1015B, VAL1032A, VAL1032B, VAL954A
• A-P: ALA1066A, ALA1134A, ALA1194A, ALA7P, ARG1137A, ARG1180A, ARG1192A, ARG1214A, ARG8P, ASN1148A, ASP1131A, ASP1135A, ASP1140A, ASP1145A, ASP1147A, ASP1150A, ASP1157A, ASP1210A, ASP1217A, CYS1155A, GLN5P, GLU1067A, GLU1133A, GLU1138A, GLU1139A, GLU1213A, GLY1151A, GLY1212A, GLY1220A, ILE1129A, ILE1156A, ILE1193A, ILE1218A, LEU1070A, LEU1143A, LEU1146A, LEU1222A, LYS1149A, LYS1219A, LYS4P, PHE1144A, PHE1195A, PHE1209A, PHE1215A, PHE1223A, PRO1068A, PRO1178A, PRO1191A, SER10P, SER1130A, SER1132A, SER1141A, THR11P, THR6P, TRP1216A, TYR1142A, TYR1154A, TYR1211A, VAL1136A, VAL1153A, VAL1177A, VAL1179A, VAL1181A
• B-Q: ALA1066B, ALA1134B, ALA1194B, ALA1Q, ALA7Q, ARG1137B, ARG1180B, ARG1192B, ARG1214B, ARG2Q, ARG8Q, ASN1148B, ASP1131B, ASP1135B, ASP1140B, ASP1145B, ASP1147B, ASP1150B, ASP1157B, ASP1210B, ASP1217B, CYS1155B, GLN5Q, GLU1067B, GLU1133B, GLU1138B, GLU1139B, GLU1213B, GLY1151B, GLY1212B, GLY1220B, ILE1129B, ILE1156B, ILE1193B, ILE1218B, LEU1070B, LEU1143B, LEU1146B, LEU1222B, LYS1149B, LYS1219B, LYS1221B, LYS4Q, PHE1144B, PHE1195B, PHE1209B, PHE1215B, PHE1223B, PRO1068B, PRO1178B, PRO1191B, SER10Q, SER1130B, SER1132B, SER1141B, THR11Q, THR3Q, THR6Q, TRP1216B, TYR1142B, TYR1154B, TYR1211B, VAL1136B, VAL1153B, VAL1177B, VAL1179B