3HKZ

the x-ray crystal structure of rna polymerase from archaea

• Total interactions analyzed: 325
• Total true interactions: 67
• Strongest Interaction:
  • Chains: D-L
  • Int. Res.: 125
  • Norm. En. per Res.: -4.4219
• Hub Node: A(10)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-132.3638	-135.6512	-1089.9	-1357.915	354	119	41	49922	11	130	138
A-B	-347.4314	-138.7408	-2061.0	-2547.1723	641	210	41	88363	20	211	192
A-D	0.0	20.2559	-7.6899	12.566	20	0	0	340	1	10	8
A-E	-11.1986	0.0	-7.359	-18.5575	16	1	0	236	0	2	3
A-G	-62.4172	-29.07	-299.48	-390.9672	123	49	10	15490	3	38	33
A-H	0.0	-14.7072	-138.974	-153.6812	66	4	5	6383	1	13	11
A-K	-35.5493	-21.5171	-211.302	-268.3684	126	10	8	11014	1	34	35
A-L	-10.51	-34.4889	-169.574	-214.5729	73	20	5	7921	3	24	22
A-Y	-4.5398	-10.2911	-50.2786	-65.1095	34	4	0	2558	2	23	29
A-J	-23.8658	24.5188	-133.049	-132.3961	66	31	1	6257	1	30	35
C-B	-13.6554	7.8285	-188.467	-194.294	131	16	11	10077	0	14	18
C-E	-15.8475	-1.274	-140.961	-158.0825	48	18	2	5585	0	7	6
C-G	0.0	0.0	-0.0015	-0.0015	2	0	0	1	0	0	1
C-H	-32.1625	-12.737	-270.85	-315.7496	101	27	9	11763	5	42	30
C-K	-21.146	-18.9551	-251.229	-291.3302	89	34	9	10665	1	16	14
C-Y	0.0	17.598	-38.4996	-20.9016	26	3	0	1777	0	12	20
C-J	0.0	0.624	-46.4183	-45.7943	55	2	0	2684	0	26	29
B-D	-24.3978	6.0107	-366.699	-385.086	146	38	6	15929	2	46	52
B-E	0.0	1.1241	-46.5388	-45.4147	32	3	1	2265	0	12	8
B-F	0.0	0.0	-4.4857	-4.4857	9	0	1	268	0	0	0
B-G	0.0	0.0	-0.0014	-0.0014	5	0	0	4	0	1	2
B-K	0.0	0.0	-7.9127	-7.9127	15	0	0	449	0	0	1
B-L	-3.3456	4.2345	-46.8672	-45.9783	34	4	0	2236	1	9	9
B-N	-83.1577	-14.7827	-524.291	-622.2315	159	67	7	21155	3	28	32
B-P	-17.0555	-26.5068	-211.856	-255.4184	101	27	8	9908	0	33	25
D-G	0.0	0.0	-0.4599	-0.4599	6	0	0	67	0	4	2
D-L	-68.3128	-107.5989	-376.823	-552.7346	125	21	16	19198	9	49	53
D-N	0.0	4.6049	-213.441	-208.8361	100	26	9	10963	0	18	14
D-P	-54.6585	-51.3096	-127.743	-233.7111	54	6	11	5511	3	19	10
E-F	-87.3867	-65.847	-454.609	-607.8426	149	37	18	20841	2	39	29
E-K	-4.4425	0.0	-99.4134	-103.8559	42	15	2	4183	0	5	1
E-J	0.0	6.8165	-20.2944	-13.4779	24	0	0	1043	0	12	10
G-J	0.0	23.3105	-18.233	5.0775	18	7	0	1748	0	5	13
H-K	-16.3699	0.0125	-89.6654	-106.0228	39	5	2	3596	4	13	10
H-Y	-16.7504	11.8749	-110.328	-115.2034	65	19	0	5858	2	28	29
K-J	0.0	0.0	-9.6306	-9.6306	24	0	1	902	0	6	8
L-J	0.0	0.0	-0.2468	-0.2468	9	0	0	101	0	1	1
N-P	0.0	5.5034	-21.3556	-15.8522	11	2	0	783	0	2	4
I-M	-110.3006	-134.7658	-1097.4	-1342.4664	348	124	42	50140	12	131	140
I-J	-358.2957	-142.5266	-2099.7	-2600.5223	629	202	40	88354	19	211	190
I-O	0.0	19.3163	-8.1108	11.2055	20	2	0	341	1	10	8
I-Q	-7.729	0.0	-6.5326	-14.2617	14	1	0	251	0	2	3
I-S	-69.6034	-15.8018	-92.5585	-177.9637	70	8	3	4782	2	14	11
I-T	-3.6144	-13.5278			8
I-U	-16.8836	-25.8102			10
I-V	-9.2206	-40.2143			12
I-Z	-3.6657	-8.0769			7
M-J	-10.211	-4.049	-207.072	-221.332	133	15	13	10680	0	16	18
M-Q	0.0	-0.2888	-127.192	-127.4808	44	25	2	5441	0	9	7
M-T	-21.1247	-8.27			15
M-U	-17.9508	-6.1823			13
M-Z	0.0	10.7035			4
J-O	-25.4156	8.8885	-400.748	-417.2751	152	51	6	16605	2	46	53
J-Q	0.0	1.5562	-26.3926	-24.8364	30	3	1	1940	0	9	7
J-R	0.0	0.0	-1.7098	-1.7098	10	0	1	189	0	0	0
J-S	0.0	0.0	-0.0052	-0.0052	5	0	0	7	0	1	2
J-V	0.0	4.0053			5
J-W	-71.6656	-14.6447			25
J-X	-13.7741	-29.7121			16
O-S	0.0	0.0	-0.2634	-0.2634	6	0	0	50	0	3	2
O-V	-59.874	-162.5155			24
O-W	-2.4226	4.5376			9
O-X	-29.7767	-51.5572			10
Q-R	-106.7659	-59.181	-452.721	-618.6679	147	38	20	19634	3	37	28
T-U	-11.4948	-16.0583			10
T-Z	-12.9338	-2.7826			9
W-X	0.0	5.6679			2

Interface residues

• A-C: ALA113C, ALA120A, ALA128A, ALA129A, ALA240C, ALA299A, ALA317C, ALA343C, ALA345C, ALA346C, ALA357C, ALA358C, ALA359C, ALA472A, ALA476A, ALA55C, ALA65C, ALA69C, ALA74C, ALA75C, ALA810A, ALA826A, ALA832A, ALA849A, ALA861A, ARG106C, ARG124A, ARG130A, ARG131A, ARG134C, ARG203A, ARG239C, ARG290C, ARG301A, ARG308A, ARG310A, ARG311C, ARG322C, ARG327C, ARG331C, ARG344C, ARG360C, ARG427A, ARG45C, ARG490A, ARG690A, ARG812A, ARG821A, ARG822A, ARG831A, ARG839A, ARG870A, ARG874A, ASN279A, ASN312A, ASN339C, ASN34C, ASN372C, ASN38C, ASN454A, ASN485A, ASN5A, ASN605A, ASN825A, ASN869A, ASP112C, ASP198A, ASP254C, ASP278A, ASP307C, ASP309C, ASP30C, ASP318C, ASP31C, ASP356C, ASP362C, ASP46C, ASP49C, ASP53C, ASP808A, ASP829A, ASP835A, ASP852A, ASP853A, ASP867A, GLN243C, GLN300A, GLN304C, GLN328C, GLN606A, GLN607A, GLN76C, GLN815A, GLN820A, GLN847A, GLN84C, GLU109C, GLU134A, GLU172C, GLU193A, GLU280A, GLU337C, GLU348C, GLU364C, GLU365C, GLU371C, GLU387C, GLU40C, GLU471A, GLU475A, GLU478A, GLU47C, GLU58C, GLU618A, GLU61C, GLU685A, GLU68C, GLU804A, GLU80C, GLU833A, GLU844A, GLU873A, GLU92A, GLY103C, GLY12A, GLY196A, GLY304A, GLY305C, GLY307A, GLY311A, GLY315A, GLY324C, GLY330C, GLY333C, GLY336C, GLY361C, GLY368C, GLY376C, GLY382C, GLY384C, GLY492A, GLY62C, GLY67C, GLY689A, GLY71C, GLY79C, GLY805A, GLY817A, GLY82C, GLY836A, GLY843A, GLY851A, GLY854A, GLY85A, GLY863A, GLY877A, GLY8A, HIS312C, HIS332C, HIS353C, HIS377C, HIS426A, HIS613A, HIS83A, HIS862A, HIS89A, ILE108C, ILE110C, ILE121A, ILE13A, ILE194A, ILE241C, ILE28C, ILE294C, ILE297C, ILE310C, ILE313C, ILE316C, ILE325C, ILE329C, ILE36C, ILE373C, ILE374C, ILE375C, ILE379C, ILE41C, ILE428A, ILE479A, ILE48C, ILE495A, ILE51C, ILE56C, ILE64C, ILE687A, ILE6A, ILE70C, ILE72C, ILE824A, ILE871A, ILE90A, ILE9A, LEU102C, LEU104C, LEU107C, LEU14A, LEU195A, LEU24C, LEU252C, LEU298A, LEU301C, LEU302A, LEU306C, LEU313A, LEU314C, LEU315C, LEU32C, LEU342C, LEU354C, LEU355C, LEU35C, LEU37C, LEU381C, LEU388C, LEU425A, LEU54C, LEU63C, LEU692A, LEU823A, LEU827A, LEU830A, LEU841A, LEU86A, LYS10A, LYS122A, LYS123A, LYS137A, LYS27C, LYS303A, LYS316A, LYS338C, LYS33C, LYS352C, LYS367C, LYS380C, LYS39C, LYS50C, LYS57C, LYS617A, LYS7A, LYS864A, LYS879A, LYS88A, MET173C, MET207A, MET320C, MET385C, MET430A, MET819A, MET858A, MET85C, PHE11A, PHE277A, PHE309A, PHE347C, PHE366C, PHE52C, PHE856A, PHE872A, PHE93A, PRO105C, PRO126A, PRO199A, PRO204A, PRO25C, PRO378C, PRO423A, PRO451A, PRO452A, PRO489A, PRO608A, PRO66C, PRO686A, PRO688A, PRO81C, PRO857A, SER127A, SER202A, SER314A, SER340C, SER424A, SER429A, SER60C, SER77C, SER816A, SER828A, SER840A, SER860A, THR119C, THR201A, THR297A, THR321C, THR323C, THR335C, THR350C, THR383C, THR44C, THR488A, THR809A, THR813A, THR837A, THR83C, THR865A, THR86C, TRP125A, TRP614A, TRP878A, TYR197A, TYR453A, TYR491A, TYR59C, TYR818A, TYR834A, TYR842A, TYR850A, TYR859A, VAL111C, VAL192A, VAL242C, VAL29C, VAL308C, VAL319C, VAL334C, VAL341C, VAL349C, VAL351C, VAL363C, VAL369C, VAL370C, VAL386C, VAL43C, VAL73C, VAL78C, VAL807A, VAL838A, VAL845A, VAL846A, VAL848A, VAL84A, VAL855A, VAL866A, VAL868A, VAL875A, VAL876A, VAL87A
• A-B: 7181CB7.2579, ALA1003B, ALA1005B, ALA1042B, ALA1096B, ALA274A, ALA299A, ALA339B, ALA344A, ALA432A, ALA442B, ALA455A, ALA471B, ALA472A, ALA474A, ALA476A, ALA498A, ALA499A, ALA506A, ALA618B, ALA624B, ALA627B, ALA646B, ALA652B, ALA725A, ALA725B, ALA729A, ALA733A, ALA744A, ALA745A, ALA799A, ALA800A, ALA810A, ALA914B, ALA929B, ALA966B, ALA998B, ARG1004B, ARG1006B, ARG1014B, ARG1020B, ARG1022B, ARG1027B, ARG1033B, ARG1048B, ARG1055B, ARG10B, ARG1112B, ARG203A, ARG20A, ARG220A, ARG301A, ARG308A, ARG310A, ARG317A, ARG323A, ARG329B, ARG330B, ARG352A, ARG385A, ARG389A, ARG421A, ARG427A, ARG436A, ARG443B, ARG444A, ARG452B, ARG48A, ARG577B, ARG633A, ARG637A, ARG647A, ARG665B, ARG734A, ARG742B, ARG753A, ARG759A, ARG764A, ARG781B, ARG787A, ARG803A, ARG812A, ARG821A, ARG822A, ARG831A, ARG833B, ARG918B, ARG974B, ARG982B, ASN1052B, ASN1073B, ASN1087B, ASN312A, ASN331A, ASN376A, ASN420A, ASN439B, ASN446A, ASN463A, ASN463B, ASN469B, ASN485A, ASN5A, ASN605A, ASN623B, ASN63A, ASN661B, ASN666B, ASN67A, ASN723A, ASN733B, ASN739A, ASN825A, ASN911B, ASP1034B, ASP1047B, ASP1051B, ASP1054B, ASP1062B, ASP1071B, ASP1117B, ASP17A, ASP233A, ASP278A, ASP319A, ASP329A, ASP333B, ASP334B, ASP336B, ASP444B, ASP456A, ASP458A, ASP460A, ASP501A, ASP561B, ASP617B, ASP632B, ASP636B, ASP650A, ASP736B, ASP808A, ASP829A, ASP876B, ASP896B, ASP965B, ASP972B, ASP999B, CYS1035B, CYS1061B, CYS1064B, CYS1079B, CYS450A, CYS454B, CYS58A, CYS61A, CYS68A, GLN1010B, GLN1015B, GLN1063B, GLN1102B, GLN300A, GLN422A, GLN437B, GLN449B, GLN468A, GLN500A, GLN523A, GLN642A, GLN662B, GLN742A, GLN750A, GLN815A, GLN820A, GLN884B, GLN923B, GLN954B, GLN977B, GLU1018B, GLU1023B, GLU1030B, GLU1032B, GLU1103B, GLU1116B, GLU18A, GLU306A, GLU331B, GLU408A, GLU441B, GLU457B, GLU460B, GLU461A, GLU470A, GLU471A, GLU475A, GLU478A, GLU519A, GLU520A, GLU53A, GLU565B, GLU619B, GLU620B, GLU621B, GLU622B, GLU629B, GLU640A, GLU641B, GLU649A, GLU659B, GLU735B, GLU794A, GLU804A, GLU926B, GLU951B, GLU968B, GLY1007B, GLY1019B, GLY1024B, GLY1025B, GLY1029B, GLY1038B, GLY1040B, GLY1065B, GLY1068B, GLY12A, GLY304A, GLY307A, GLY311A, GLY315A, GLY440A, GLY447B, GLY451B, GLY459A, GLY461B, GLY465B, GLY497A, GLY505A, GLY50A, GLY526A, GLY62A, GLY643A, GLY66A, GLY70A, GLY731B, GLY732A, GLY735A, GLY73A, GLY760A, GLY789A, GLY801A, GLY802A, GLY805A, GLY817A, GLY842B, GLY85A, GLY875B, GLY886B, GLY889B, GLY8A, GLY922B, GLY927B, GLY976B, GLY986B, HIS1002B, HIS1082B, HIS337B, HIS426A, HIS446B, HIS465A, HIS557B, HIS567B, HIS637B, HIS639B, HIS660B, HIS71A, HIS768A, HIS798A, HIS83A, HIS841B, HIS913B, HIS995B, ILE1011B, ILE1037B, ILE1058B, ILE1067B, ILE1081B, ILE1101B, ILE1108B, ILE1109B, ILE13A, ILE19A, ILE208A, ILE217A, ILE219A, ILE326A, ILE332A, ILE342A, ILE343A, ILE379A, ILE416A, ILE428A, ILE473A, ILE479A, ILE503A, ILE524A, ILE52A, ILE558B, ILE563B, ILE636A, ILE647B, ILE655B, ILE6A, ILE738B, ILE739B, ILE740A, ILE757A, ILE824A, ILE871B, ILE874B, ILE888B, ILE892B, ILE909B, ILE924B, ILE928B, ILE950B, ILE979B, ILE983B, ILE9A, LEU1001B, LEU1012B, LEU1026B, LEU1036B, LEU1044B, LEU1045B, LEU1049B, LEU1050B, LEU1088B, LEU1099B, LEU1100B, LEU1104B, LEU1113B, LEU1115B, LEU14A, LEU209A, LEU212A, LEU235A, LEU239A, LEU298A, LEU302A, LEU313A, LEU347A, LEU411A, LEU418A, LEU425A, LEU438A, LEU441A, LEU445A, LEU445B, LEU447A, LEU448A, LEU464A, LEU466B, LEU481A, LEU49A, LEU508A, LEU515A, LEU516A, LEU579B, LEU616B, LEU628B, LEU640B, LEU641A, LEU648A, LEU648B, LEU65A, LEU738A, LEU747A, LEU766A, LEU77A, LEU790A, LEU795A, LEU806A, LEU830A, LEU86A, LEU891B, LEU910B, LEU915B, LEU921B, LEU963B, LEU993B, LYS1000B, LYS1046B, LYS1072B, LYS1074B, LYS1076B, LYS1085B, LYS1098B, LYS10A, LYS1118B, LYS178B, LYS21A, LYS238A, LYS305A, LYS316A, LYS345A, LYS439A, LYS468B, LYS477A, LYS484A, LYS4A, LYS4A5, LYS57A, LYS658A, LYS758A, LYS770A, LYS791A, LYS7A, LYS877B, LYS885B, LYS978B, LYS980B, MET1031B, MET1043B, MET1057B, MET1105B, MET1107B, MET207A, MET22A, MET430A, MET431A, MET453B, MET462A, MET480A, MET646A, MET672B, MET727B, MET728A, MET734B, MET743A, MET746A, MET762A, MET844B, MET858A, MET890B, MET919B, MET925B, MET996B, PHE1028B, PHE1039B, PHE1089B, PHE1097B, PHE11A, PHE277A, PHE309A, PHE320A, PHE419A, PHE440B, PHE443A, PHE456B, PHE457A, PHE632A, PHE638A, PHE644A, PHE724A, PHE729B, PHE72A, PHE769A, PHE786A, PHE796A, PHE797A, PHE856A, PHE878B, PHE945B, PHE985B, PRO1008B, PRO1016B, PRO1080B, PRO1090B, PRO1111B, PRO16A, PRO213A, PRO215A, PRO216A, PRO221A, PRO328A, PRO330A, PRO340A, PRO350A, PRO423A, PRO438B, PRO451A, PRO455B, PRO459B, PRO462B, PRO467A, PRO489A, PRO54A, PRO59A, PRO645B, PRO658B, PRO664B, PRO69A, PRO767A, PRO771A, PRO792A, PRO898B, PRO912B, PRO916B, PRO944B, PRO949B, PRO964B, SER1053B, SER1094B, SER1106B, SER1110B, SER15A, SER202A, SER222A, SER23A, SER314A, SER321A, SER322A, SER327A, SER424A, SER429A, SER464B, SER469A, SER504A, SER644B, SER652A, SER663B, SER728B, SER736A, SER737B, SER784A, SER785A, SER814A, SER816A, SER828A, SER917B, SER981B, THR1013B, THR1017B, THR1041B, THR1056B, THR1092B, THR200A, THR201A, THR210A, THR218A, THR275A, THR297A, THR324A, THR346A, THR348A, THR442A, THR448B, THR458B, THR513A, THR514A, THR517A, THR560B, THR60A, THR638B, THR645A, THR64A, THR667B, THR730B, THR731A, THR741A, THR763A, THR765A, THR788A, THR793A, THR809A, THR813A, THR873B, THR920B, THR967B, THR975B, TRP1069B, TRP206A, TRP450B, TRP643B, TYR1059B, TYR1066B, TYR1070B, TYR1077B, TYR1095B, TYR276A, TYR338B, TYR377A, TYR390A, TYR453A, TYR502A, TYR507A, TYR545A, TYR625B, TYR657B, TYR668B, TYR726A, TYR732B, TYR761A, TYR772A, TYR788B, TYR818A, TYR946B, TYR962B, TYR984B, VAL1009B, VAL1060B, VAL1078B, VAL1091B, VAL1093B, VAL1114B, VAL1119B, VAL211A, VAL214A, VAL24A, VAL273A, VAL318A, VAL325A, VAL349A, VAL378A, VAL417A, VAL466A, VAL467B, VAL482A, VAL559B, VAL626B, VAL639A, VAL651A, VAL726B, VAL727A, VAL737A, VAL752A, VAL807A, VAL811A, VAL84A, VAL887B, VAL970B, VAL997B
• A-D: ARG211D, ARG218D, ARG543A, ARG647A, ASN26D, ASP224D, ASP650A, CYS206D, GLN523A, GLU207D, GLU208D, GLU223D, GLU23D, GLU519A, GLU649A, LEU22D, PHE724A, PRO21D, TYR212D, TYR226D
• A-E: ARG352A, ASN16E, ASN5A, ASP63E, GLU470A, GLU471A, GLU475A, GLY404A, GLY62E, GLY64E, PHE61E, PRO15E, PRO403A, SER469A, THR354A, VAL60E
• A-G: ALA538A, ALA541A, ARG114G, ARG543A, ARG573A, ARG63G, ASN108G, ASN25G, ASN47G, ASN577A, ASN590A, ASN723A, ASN87G, ASN88G, ASN90G, ASP41G, ASP44G, ASP579A, ASP583A, ASP69G, ASP70G, ASP720A, ASP83G, CYS575A, CYS580A, CYS72G, GLN550A, GLN642A, GLU110G, GLU536A, GLU544A, GLU578A, GLU595A, GLU80G, GLY21G, GLY535A, GLY548A, GLY596A, GLY73G, GLY75G, GLY877A, GLY89G, HIS563A, HIS582A, HIS68G, HIS74G, ILE106G, ILE42G, ILE43G, ILE46G, ILE48G, ILE539A, ILE552A, ILE588A, ILE592A, ILE77G, ILE95G, LEU113G, LEU23G, LEU26G, LEU508A, LEU515A, LEU534A, LEU540A, LEU593A, LEU594A, LEU81G, LEU86G, LYS109G, LYS24G, LYS512A, LYS518A, LYS549A, LYS589A, LYS82G, LYS879A, LYS91G, MET28G, PHE112G, PHE40G, PHE49G, PHE71G, PHE722A, PHE724A, PRO537A, PRO542A, PRO572A, PRO581A, PRO64G, PRO721A, SER107G, SER22G, SER27G, SER45G, SER553A, SER584A, SER67G, SER84G, SER85G, THR115G, THR510A, THR513A, THR514A, THR547A, THR79G, THR93G, TRP878A, TYR507A, TYR545A, TYR546A, TYR585A, TYR66G, TYR76G, TYR92G, VAL511A, VAL551A, VAL568A, VAL586A, VAL587A, VAL597A, VAL727A, VAL78G, VAL876A
• A-H: ALA47H, ALA849A, ARG124A, ARG38H, ARG46H, ARG64H, ARG67H, ARG79H, ARG839A, ASP835A, ASP852A, ASP853A, GLN41H, GLN70H, GLN847A, GLU34H, GLU40H, GLU74H, GLU833A, GLU844A, GLY36H, GLY60H, GLY73H, GLY836A, GLY843A, GLY851A, GLY854A, GLY863A, HIS862A, ILE121A, ILE31H, ILE37H, ILE45H, ILE65H, ILE82H, LEU32H, LEU35H, LEU42H, LEU71H, LEU841A, LYS122A, LYS123A, LYS68H, LYS864A, PRO39H, PRO43H, SER69H, SER77H, SER840A, THR837A, THR865A, TRP125A, TRP44H, TYR72H, TYR78H, TYR80H, TYR842A, TYR850A, VAL75H, VAL76H, VAL81H, VAL838A, VAL845A, VAL846A, VAL848A, VAL855A
• A-K: ALA33K, ALA38K, ALA40K, ALA44K, ALA472A, ALA474A, ALA476A, ALA47K, ALA49K, ALA65K, ALA832A, ALA849A, ARG29K, ARG34K, ARG352A, ARG39K, ARG409A, ARG427A, ARG434A, ARG79K, ARG80K, ARG81K, ARG831A, ARG839A, ASN16K, ASN357A, ASN485A, ASN54K, ASN55K, ASN84K, ASP12K, ASP415A, ASP52K, ASP60K, ASP621A, ASP835A, ASP852A, ASP853A, GLN42K, GLN847A, GLU17K, GLU31K, GLU351A, GLU359A, GLU470A, GLU471A, GLU475A, GLU478A, GLU66K, GLU833A, GLY404A, GLY414A, GLY46K, GLY836A, GLY854A, GLY85K, HIS14K, ILE20K, ILE32K, ILE353A, ILE358A, ILE36K, ILE406A, ILE412A, ILE416A, ILE428A, ILE473A, ILE479A, ILE486A, ILE487A, ILE53K, ILE62K, ILE64K, ILE78K, ILE87K, ILE88K, LEU13K, LEU27K, LEU361A, LEU41K, LEU43K, LEU481A, LEU56K, LEU82K, LEU90K, LYS360A, LYS477A, LYS484A, LYS864A, LYS86K, MET45K, MET480A, MET858A, PHE15K, PHE19K, PHE69K, PHE856A, PRO350A, PRO355A, PRO403A, PRO489A, PRO48K, PRO83K, SER21K, SER37K, SER469A, SER63K, THR28K, THR354A, THR59K, THR837A, TRP23K, TRP356A, TYR30K, TYR834A, TYR850A, TYR859A, VAL18K, VAL349A, VAL35K, VAL482A, VAL61K, VAL838A, VAL845A, VAL848A, VAL855A
• A-L: ALA29L, ALA41L, ALA521A, ALA528A, ARG33L, ARG34L, ARG436A, ARG444A, ARG633A, ARG637A, ASN26L, ASN331A, ASN630A, ASP329A, ASP51L, ASP529A, ASP533A, ASP60L, GLN45L, GLN522A, GLN523A, GLU14L, GLU519A, GLU520A, GLU640A, GLY30L, GLY338A, GLY37L, GLY440A, GLY526A, GLY535A, HIS22L, HIS47L, ILE332A, ILE524A, ILE532A, ILE54L, ILE57L, LEU13L, LEU32L, LEU438A, LEU441A, LEU49L, LEU525A, LEU534A, LEU58L, LYS439A, LYS518A, LYS52L, LYS531A, LYS56L, LYS7L, PHE40L, PRO328A, PRO330A, PRO46L, PRO48L, SER327A, SER39L, SER42L, SER50L, THR31L, THR59L, TYR12L, TYR43L, TYR44L, TYR546A, VAL38L, VAL437A, VAL527A, VAL530A, VAL551A, VAL55L
• A-Y: ALA128A, ALA129A, ARG116A, ARG124A, ARG131A, ARG78Y, ARG81Y, ARG82Y, ASN119A, ASN71Y, ASP70Y, ASP79Y, GLU112A, GLU69Y, GLU74Y, GLU76Y, ILE111A, ILE121A, LEU132A, LEU67Y, LYS122A, LYS66Y, LYS73Y, LYS77Y, PRO126A, SER115A, SER80Y, TRP125A, TYR114A, TYR118A, TYR135A, TYR72Y, TYR75Y, TYR842A
• A-J: ALA109J, ALA380J, ALA554A, ARG375J, ARG377J, ARG59J, ARG874A, ASN105J, ASN106J, ASN561A, ASN590A, ASP529A, ASP533A, ASP559A, ASP621A, GLU104J, GLU108J, GLU110J, GLU112J, GLU52J, GLU536A, GLU618A, GLU622A, GLU873A, GLY376J, GLY55J, GLY591A, GLY624A, GLY877A, HIS563A, ILE101J, ILE107J, ILE532A, ILE53J, ILE588A, ILE592A, ILE871A, LEU379J, LEU534A, LEU556A, LEU56J, LEU615A, LEU627A, LYS373J, LYS378J, LYS531A, LYS558A, LYS57J, LYS589A, LYS879A, PHE555A, PHE560A, PHE872A, PRO102J, PRO111J, PRO54J, PRO557A, SER620A, TRP626A, TRP878A, TYR619A, TYR623A, VAL103J, VAL530A, VAL875A, VAL876A
• C-B: ALA1042B, ALA1096B, ALA161C, ALA217C, ALA218C, ALA343C, ALA345C, ALA346C, ALA357C, ALA358C, ALA359C, ALA69C, ALA74C, ARG1033B, ARG1048B, ARG1055B, ARG1112B, ARG223C, ASN182B, ASN228C, ASN250B, ASN372C, ASP1034B, ASP1047B, ASP1051B, ASP1054B, ASP159C, ASP207B, ASP356C, ASP362C, CYS1035B, GLN249B, GLN258B, GLN76C, GLU1030B, GLU1032B, GLU1103B, GLU1116B, GLU247B, GLU251B, GLU257B, GLU364C, GLU365C, GLU371C, GLU68C, GLY1038B, GLY1040B, GLY208B, GLY361C, GLY376C, GLY382C, GLY384C, GLY67C, GLY71C, HIS353C, HIS377C, ILE1037B, ILE1058B, ILE1101B, ILE1108B, ILE1109B, ILE158C, ILE160C, ILE183B, ILE373C, ILE374C, ILE375C, ILE379C, ILE70C, ILE72C, LEU1036B, LEU1044B, LEU1045B, LEU1049B, LEU1050B, LEU1100B, LEU1104B, LEU1113B, LEU219C, LEU252B, LEU256B, LEU327B, LEU342C, LEU354C, LEU355C, LEU381C, LYS1046B, LYS1098B, LYS221C, LYS380C, MET1031B, MET1043B, MET1107B, MET385C, PHE1028B, PHE1039B, PHE1097B, PHE210B, PHE220C, PHE253B, PHE347C, PHE366C, PRO1111B, PRO254B, PRO378C, SER1094B, SER1110B, SER154C, SER155C, SER157C, SER255B, THR1041B, THR1092B, THR156C, THR179B, THR184B, THR209B, THR350C, THR383C, THR83C, TYR326B, VAL1060B, VAL1091B, VAL1093B, VAL1114B, VAL341C, VAL351C, VAL363C, VAL369C, VAL370C, VAL73C
• C-E: ALA65E, ARG12E, ARG391C, ARG395C, ASN23E, ASP63E, GLU17E, GLU387C, GLU55E, GLU56E, GLU69E, GLY19E, GLY382C, GLY384C, GLY57E, GLY62E, GLY64E, HIS377C, HIS68E, ILE13E, ILE25E, ILE379C, ILE393C, ILE58E, LEU22E, LEU381C, LEU388C, LEU394C, LEU59E, LYS20E, LYS380C, MET385C, MET390C, PHE18E, PHE61E, PRO14E, PRO15E, PRO21E, PRO378C, PRO392C, SER54E, THR383C, THR389C, THR66E, TYR67E, VAL11E, VAL386C, VAL60E
• C-G: THR44C, THR79G
• C-H: ALA270C, ALA288C, ALA289C, ALA47H, ALA52H, ARG12H, ARG290C, ARG295C, ARG311C, ARG322C, ARG327C, ARG46H, ARG53H, ARG67H, ARG79H, ASN275C, ASN34C, ASP10H, ASP268C, ASP309C, ASP30C, ASP318C, ASP31C, ASP49H, GLN26C, GLN41H, GLN70H, GLU273C, GLU279C, GLU281C, GLU282C, GLU287C, GLU291C, GLU296C, GLU74H, GLY285C, GLY324C, GLY73H, HIS14H, HIS20H, ILE13H, ILE277C, ILE280C, ILE286C, ILE28C, ILE292C, ILE293C, ILE294C, ILE310C, ILE325C, ILE45H, ILE63H, ILE65H, ILE66H, ILE82H, ILE9H, LEU16H, LEU258C, LEU262C, LEU314C, LEU32C, LEU42H, LEU71H, LYS19H, LYS271C, LYS27C, LYS299C, LYS338C, LYS68H, MET320C, PHE284C, PRO11H, PRO18H, PRO25C, PRO43H, PRO50H, SER263C, SER298C, SER48H, SER69H, SER77H, THR123C, THR274C, THR321C, THR323C, TRP44H, TYR125C, TYR15H, TYR72H, TYR78H, TYR80H, VAL17H, VAL269C, VAL272C, VAL283C, VAL29C, VAL319C, VAL51H, VAL75H, VAL76H, VAL81H
• C-K: ALA33K, ALA38K, ALA40K, ALA47K, ALA49K, ALA65C, ALA65K, ALA69C, ARG29K, ARG34K, ARG391C, ARG395C, ARG39K, ARG79K, ARG80K, ARG81K, ASN16K, ASN25K, ASP30C, ASP52K, GLN11K, GLN24K, GLN26C, GLN42K, GLU17K, GLU31K, GLU387C, GLU68C, GLU68K, GLY382C, GLY384C, GLY62C, GLY67C, HIS14K, ILE28C, ILE32K, ILE36K, ILE393C, ILE51K, ILE53K, ILE64C, ILE70C, ILE76K, ILE78K, ILE87K, ILE88K, LEU13K, LEU22K, LEU24C, LEU27K, LEU381C, LEU388C, LEU394C, LEU41K, LEU43K, LEU50K, LEU63C, LEU74K, LEU89K, LEU90K, LEU92K, LYS27C, MET385C, MET390C, MET45K, PHE15K, PHE19K, PRO25C, PRO392C, PRO48K, PRO66C, PRO75K, SER21K, SER37K, SER60C, SER91K, THR28K, THR383C, THR389C, THR77K, TRP23K, TYR30K, TYR59C, VAL18K, VAL29C, VAL35K, VAL386C, VAL73C, VAL73K
• C-Y: ARG278C, ARG322C, ARG327C, ARG331C, ARG344C, ARG81Y, ARG82Y, ASP79Y, GLN328C, GLU337C, GLY324C, GLY330C, GLY333C, GLY336C, HIS332C, HIS353C, ILE325C, LYS338C, LYS352C, MET320C, SER80Y, THR323C, THR335C, VAL326C, VAL334C, VAL349C
• C-J: ALA109J, ALA380J, ALA383J, ARG377J, ARG395C, ARG543J, ARG544J, ARG545J, ARG609J, ARG64J, ARG75J, ASP49C, ASP53C, ASP551J, ASP74J, GLN19C, GLU110J, GLU112J, GLU113J, GLU15C, GLU491J, GLU548J, GLU552J, GLU77J, GLY547J, GLY76J, ILE393C, ILE480J, ILE484J, ILE48C, ILE51C, ILE549J, ILE56C, LEU13C, LEU381J, LEU394C, LYS16C, LYS378J, LYS382J, LYS487J, LYS50C, LYS546J, LYS57C, PHE52C, PRO111J, PRO392C, SER550J, SER60C, THR488J, TRP97J, TYR115J, TYR12C, TYR59C, VAL485J, VAL553J
• B-D: ALA154D, ALA27D, ALA31D, ALA59D, ALA63D, ARG12D, ARG165D, ARG211D, ARG29D, ARG30D, ARG61D, ARG742B, ARG747B, ARG751B, ARG865B, ARG867B, ARG870B, ARG959B, ARG974B, ARG982B, ASN181D, ASN26D, ASN49D, ASN50D, ASN741B, ASP55D, ASP848B, ASP868B, ASP896B, ASP965B, ASP972B, CYS183D, CYS203D, CYS206D, CYS209D, GLN137D, GLN685B, GLN894B, GLN977B, GLU152D, GLU185D, GLU207D, GLU208D, GLU229D, GLU231D, GLU23D, GLU48D, GLU56D, GLU746B, GLU801B, GLU803B, GLU968B, GLY150D, GLY186D, GLY748B, GLY845B, GLY903B, GLY961B, GLY973B, GLY976B, HIS153D, HIS60D, HIS696B, ILE130D, ILE157D, ILE219D, ILE227D, ILE57D, ILE846B, ILE871B, ILE892B, ILE957B, ILE979B, ILE983B, LEU161D, LEU205D, LEU228D, LEU22D, LEU34D, LEU53D, LEU58D, LEU64D, LEU694B, LEU695B, LEU869B, LEU958B, LEU963B, LYS151D, LYS155D, LYS902B, LYS978B, LYS980B, MET33D, MET749B, MET897B, PHE156D, PHE221D, PHE24D, PHE46D, PHE755B, PRO184D, PRO52D, PRO893B, PRO898B, PRO964B, SER160D, SER162D, SER202D, SER32D, SER51D, SER743B, SER744B, SER752B, SER981B, THR204D, THR753B, THR900B, THR967B, THR975B, TYR166D, TYR167D, TYR212D, TYR226D, TYR35D, TYR54D, TYR684B, TYR697B, TYR899B, TYR960B, TYR962B, TYR971B, VAL159D, VAL163D, VAL164D, VAL180D, VAL182D, VAL233D, VAL25D, VAL745B, VAL847B, VAL895B, VAL901B, VAL904B, VAL905B, VAL969B, VAL970B
• B-E: ALA1042B, ARG12E, ASN1087B, ASP1084B, ASP1117B, ASP63E, GLN33E, GLU69E, GLY1040B, GLY1083B, GLY62E, HIS68E, ILE10E, ILE58E, LEU1088B, LYS1046B, LYS1085B, LYS1118B, LYS37E, MET1043B, PHE61E, SER1086B, SER151E, SER9E, THR152E, TYR1077B, TYR34E, TYR67E, VAL1119B, VAL11E, VAL153E, VAL60E
• B-F: ASP1117B, LYS1118B, MET1F, PHE1089B, SER2F, SER3F, TYR5F, VAL1119B, VAL4F
• B-G: ASN25G, LYS24G, LYS980B, SER45G, SER981B
• B-K: ALA1042B, ALA33K, ALA38K, ARG29K, ARG34K, GLY1038B, GLY1040B, ILE1037B, LEU1044B, LEU41K, MET1043B, PHE1039B, SER37K, THR1041B, TYR30K
• B-L: ARG33L, ARG742B, ARG974B, ASN26L, ASP21L, ASP896B, ASP972B, GLN45L, GLN977B, GLY889B, GLY973B, GLY976B, HIS22L, HIS47L, ILE739B, ILE874B, ILE892B, LEU27L, LEU49L, LEU891B, MET890B, PHE729B, PRO46L, PRO48L, PRO893B, SER50L, THR23L, THR730B, THR873B, THR975B, TYR43L, TYR44L, TYR732B, VAL895B
• B-N: ALA15N, ALA681B, ALA682B, ALA718B, ALA722B, ALA725B, ALA929B, ALA933B, ALA934B, ALA966B, ARG42N, ARG46N, ARG47N, ARG64N, ARG687B, ARG6N, ARG700B, ARG716B, ARG747B, ARG751B, ARG865B, ARG867B, ARG881B, ASN26N, ASN30N, ASN57N, ASN683B, ASN715B, ASN720B, ASN721B, ASN741B, ASN938B, ASP136B, ASP144B, ASP147B, ASP36N, ASP54N, ASP848B, ASP907B, CYS10N, CYS44N, CYS45N, CYS7N, GLN685B, GLN699B, GLN894B, GLU140B, GLU143B, GLU58N, GLU746B, GLU926B, GLU968B, GLY11N, GLY142B, GLY32N, GLY678B, GLY712B, GLY719B, GLY748B, GLY903B, GLY927B, GLY930B, GLY937B, GLY961B, GLY986B, HIS52N, HIS61N, HIS696B, ILE139B, ILE141B, ILE14N, ILE22N, ILE3N, ILE55N, ILE56N, ILE5N, ILE60N, ILE723B, ILE908B, ILE928B, ILE939B, ILE957B, LEU135B, LEU138B, LEU2N, LEU35N, LEU49N, LEU50N, LEU679B, LEU686B, LEU694B, LEU695B, LEU702B, LEU724B, LEU849B, LEU851B, LEU87B, LEU935B, LEU963B, LYS146B, LYS33N, LYS41N, LYS902B, LYS931B, MET1N, MET48N, MET749B, MET83B, MET897B, PHE8N, PHE985B, PRO145B, PRO31N, PRO4N, PRO698B, PRO701B, PRO717B, PRO800B, PRO906B, SER12N, SER51N, SER743B, SER744B, SER936B, THR63N, THR714B, THR900B, THR967B, THR9N, TRP18N, TYR43N, TYR62N, TYR680B, TYR684B, TYR697B, TYR713B, TYR750B, TYR899B, TYR932B, TYR960B, TYR962B, TYR984B, TYR989B, VAL25N, VAL34N, VAL40N, VAL53N, VAL59N, VAL703B, VAL745B, VAL850B, VAL901B, VAL904B, VAL905B, VAL940B, VAL969B, VAL970B, VAL987B, VAL988B
• B-P: ALA47P, ALA856B, ALA85B, ARG25P, ARG38P, ARG71B, ARG747B, ARG751B, ARG78B, ARG790B, ARG86B, ARG88B, ASN795B, ASN859B, ASN89B, ASP794B, ASP848B, CYS29P, CYS6P, GLN17P, GLU140B, GLU143B, GLU746B, GLU793B, GLU79B, GLU801B, GLU803B, GLU84B, GLU854B, GLY142B, GLY23P, GLY30P, GLY748B, GLY76B, GLY796B, GLY7P, GLY858B, ILE139B, ILE141B, ILE33P, ILE34P, ILE44P, ILE48P, ILE773B, ILE80B, ILE811B, ILE846B, ILE852B, ILE871B, LEU138B, LEU18P, LEU21P, LEU686B, LEU791B, LEU792B, LEU810B, LEU849B, LEU851B, LEU861B, LEU869B, LEU87B, LEU90B, LYS11P, LYS32P, LYS39P, LYS43P, LYS46P, LYS805B, LYS860B, LYS863B, LYS8P, MET36P, MET83B, PHE13P, PHE35P, PRO22P, PRO40P, PRO800B, SER799B, SER81B, THR41P, THR688B, THR853B, THR855B, TRP10P, TYR28P, TYR31P, VAL20P, VAL24P, VAL37P, VAL45P, VAL70B, VAL745B, VAL774B, VAL797B, VAL798B, VAL802B, VAL847B, VAL850B, VAL862B, VAL864B
• D-G: ARG211D, ARG218D, ASN47G, ASP44G, LYS24G, SER45G
• D-L: ALA245D, ALA27D, ALA29L, ALA31D, ALA72L, ARG240D, ARG251D, ARG29D, ARG30D, ARG33L, ARG34L, ARG4L, ARG77L, ASN26D, ASN26L, ASN4D, ASN75L, ASP21L, ASP224D, ASP51L, ASP67L, ASP85L, GLN45L, GLU16L, GLU18L, GLU20L, GLU239D, GLU23D, GLU244D, GLU254D, GLU255D, GLU257D, GLU262D, GLU2L, GLU74L, GLU80D, GLU86L, GLY19D, GLY19L, GLY246D, GLY25L, GLY30L, GLY78L, GLY89L, HIS22L, HIS82L, ILE13D, ILE17L, ILE230D, ILE241D, ILE249D, ILE250D, ILE253D, ILE28D, ILE28L, ILE3D, ILE3L, ILE53L, ILE57L, ILE5L, ILE73L, ILE76L, ILE83D, ILE84L, ILE87L, LEU13L, LEU15D, LEU15L, LEU228D, LEU22D, LEU242D, LEU243D, LEU24L, LEU256D, LEU260D, LEU27L, LEU32L, LEU34D, LEU5D, LEU69L, LEU6D, LEU70L, LEU90L, LYS151D, LYS237D, LYS247D, LYS252D, LYS258D, LYS259D, LYS265D, LYS52L, LYS66L, LYS88L, LYS8D, LYS92L, MET1L, MET79L, PHE17D, PHE24D, PRO21D, PRO238D, PRO48L, PRO65L, SER248D, SER2D, SER32D, SER50L, SER81L, SER8L, THR23L, THR31L, THR64L, THR80L, THR91L, TYR20D, TYR226D, TYR35D, TYR43L, TYR83L, VAL16D, VAL25D, VAL261D, VAL263D, VAL264D, VAL55L
• D-N: ALA102D, ALA154D, ALA15N, ALA40D, ALA59D, ALA63D, ARG107D, ARG12D, ARG42N, ARG61D, ARG64N, ARG6N, ASN136D, ASN49D, ASN50D, ASN57N, ASP127D, ASP16N, ASP54N, ASP9D, CYS10N, CYS44N, CYS45N, CYS7N, GLN137D, GLN19N, GLU105D, GLU185D, GLU231D, GLY11N, GLY126D, GLY134D, GLY234D, HIS52N, HIS60D, HIS61N, ILE109D, ILE124D, ILE128D, ILE130D, ILE14N, ILE157D, ILE38D, ILE3N, ILE55N, ILE56N, ILE57D, ILE5N, ILE60N, ILE65D, LEU132D, LEU133D, LEU13N, LEU161D, LEU236D, LEU2N, LEU53D, LEU58D, LEU62D, LEU64D, LYS138D, LYS155D, LYS17N, LYS41N, MET108D, MET1N, MET33D, MET39D, PHE156D, PHE67D, PHE8N, PRO106D, PRO123D, PRO129D, PRO158D, PRO4N, PRO52D, PRO66D, SER111D, SER125D, SER12N, SER160D, SER232D, SER235D, SER51D, THR11D, THR135D, THR204D, THR63N, THR9N, TRP18N, TYR110D, TYR54D, TYR62N, VAL131D, VAL159D, VAL163D, VAL233D, VAL41D, VAL59N
• D-P: ALA143D, ALA154D, ALA40D, ALA47P, ALA59D, ALA63D, ARG144D, ARG146D, ARG38P, ARG61D, ASN136D, ASN49D, ASN50D, ASP42D, ASP43D, ASP55D, GLU142D, GLU152D, GLU48D, GLU56D, HIS153D, HIS60D, ILE139D, ILE42P, ILE44P, ILE47D, ILE48P, ILE57D, LEU141D, LEU53D, LEU58D, LEU62D, LEU64D, LYS138D, LYS155D, LYS39P, LYS43P, LYS46P, LYS8P, LYS95D, PHE13P, PHE156D, PHE46D, PRO40P, SER140D, SER51D, THR135D, THR41P, TYR45D, TYR54D, VAL37P, VAL41D, VAL44D, VAL45P
• E-F: ALA144E, ALA17F, ALA47E, ALA70F, ALA73F, ALA7E, ARG143E, ARG145E, ARG26F, ARG31E, ARG36F, ARG69F, ARG84F, ARG8E, ASN100E, ASN32F, ASN50E, ASP105E, ASP23F, ASP39F, ASP41E, ASP67F, ASP73E, ASP81F, CYS76F, GLN166E, GLN33E, GLN35E, GLN35F, GLN53F, GLN82E, GLN91E, GLU36E, GLU66F, GLU69E, GLU71E, GLU82F, GLU83E, GLU86E, GLU88E, GLU8F, GLU9F, GLY102E, GLY28F, GLY29F, GLY43E, GLY87E, HIS10F, ILE10E, ILE12F, ILE175E, ILE25F, ILE38E, ILE48E, ILE56F, ILE5E, ILE6F, ILE71F, ILE75E, ILE75F, ILE86F, LEU101E, LEU169E, LEU172E, LEU20F, LEU21F, LEU27E, LEU30E, LEU33F, LEU34F, LEU39E, LEU41F, LEU42E, LEU44E, LEU46E, LEU49E, LEU4E, LEU72F, LEU87F, LEU90E, LYS141E, LYS179E, LYS180E, LYS18F, LYS19F, LYS37E, LYS3E, LYS40E, LYS46F, LYS52E, LYS6E, MET104E, MET1E, MET1F, MET74E, MET89F, PHE72E, PRO103E, PRO13F, PRO158E, PRO167E, PRO77F, PRO79E, SER15F, SER27F, SER2F, SER30F, SER31F, SER3F, SER43F, SER74F, SER80F, SER85F, SER9E, THR176E, THR178E, THR22F, THR37F, THR53E, THR76E, THR78F, THR79F, TYR11F, TYR14F, TYR168E, TYR2E, TYR34E, TYR38F, TYR40F, TYR5F, TYR77E, VAL11E, VAL142E, VAL16F, VAL24F, VAL44F, VAL45E, VAL4F, VAL68F, VAL70E, VAL78E, VAL7F, VAL80E, VAL81E, VAL83F, VAL84E, VAL85E, VAL88F, VAL99E
• E-K: ALA38K, ALA40K, ALA44K, ALA47K, ALA49K, ALA65E, ARG12E, ARG34K, ARG39K, ARG79K, ARG81K, ASN16E, ASP63E, GLN42K, GLU17E, GLU56E, GLY19E, GLY46K, GLY57E, GLY62E, GLY64E, ILE13E, ILE58E, ILE76K, LEU41K, LEU43K, LEU50K, LEU59E, LYS20E, MET45K, PHE18E, PHE61E, PRO14E, PRO15E, PRO48K, PRO75K, SER37K, THR66E, THR77K, TYR30K, VAL35K, VAL60E
• E-J: ARG543J, ARG609J, ASN23E, ASN28E, ASN50E, ASP606J, GLN610J, GLU24E, GLU548J, GLU55E, GLY19E, GLY547J, GLY600J, ILE549J, ILE594J, LEU22E, LEU27E, LYS20E, LYS52E, LYS546J, LYS612J, PRO21E, SER54E, THR590J
• G-J: ALA6G, ARG375J, ARG377J, ASN108G, ASN62G, GLN7G, GLU110G, GLY376J, ILE105G, LEU379J, LYS109G, LYS373J, LYS378J, LYS61G, SER107G, TYR76G, VAL374J, VAL5G
• H-K: ALA28H, ARG64H, ARG67H, ASN16K, ASN84K, ASP12K, GLN11K, GLU17K, GLU21H, GLU27H, GLU34H, GLU74H, GLY36H, GLY85K, HIS14K, ILE20K, ILE31H, ILE37H, ILE65H, ILE66H, LEU13K, LEU22K, LEU23H, LEU32H, LEU35H, LEU82K, LYS30H, LYS33H, LYS86K, PHE15K, PHE19K, PRO83K, SER69H, SER77H, TYR72H, TYR78H, VAL18K, VAL75H, VAL76H
• H-Y: ALA28H, ALA47H, ALA57H, ALA64Y, ARG38H, ARG46H, ARG46Y, ARG78Y, ASN24H, ASN47Y, ASN56H, ASN56Y, ASN71Y, ASP26H, ASP40Y, ASP52Y, ASP61H, ASP70Y, ASP79Y, GLN41H, GLU27H, GLU40H, GLU49Y, GLU62Y, GLU63Y, GLU74Y, GLY36H, GLY60H, ILE25H, ILE37H, ILE45H, ILE50Y, ILE59Y, ILE62H, ILE82H, LEU23H, LEU32H, LEU43Y, LEU44Y, LEU54Y, LEU55Y, LEU61Y, LEU67Y, LYS30H, LYS33H, LYS58H, LYS58Y, LYS65Y, LYS66Y, LYS73Y, LYS77Y, MET45Y, PHE68Y, PRO39H, PRO59H, SER48H, SER80Y, THR48Y, THR60Y, TRP51Y, TYR29H, TYR75Y, TYR80H, VAL22H, VAL81H
• K-J: ALA49K, ARG26K, ARG483J, ARG64J, ARG70K, ARG71K, ASN481J, ASN54K, ASN55K, ASP44J, ASP52K, GLN46J, GLU486J, GLY72K, ILE480J, ILE484J, ILE51K, ILE53K, LEU50K, LEU92K, LYS487J, LYS62J, PHE69K, PRO48K
• L-J: ASN11L, ASP60L, GLU9L, ILE53J, LEU58L, LYS57J, PRO54J, SER39L, THR59L
• N-P: ARG38P, ARG64N, CYS9P, LYS8P, MET36P, PHE13P, PHE35P, THR63N, TRP10P, TYR62N, VAL37P
• I-M: ALA113M, ALA128I, ALA129I, ALA240M, ALA299I, ALA317M, ALA343M, ALA345M, ALA346M, ALA357M, ALA358M, ALA359M, ALA472I, ALA476I, ALA55M, ALA65M, ALA69M, ALA74M, ALA75M, ALA810I, ALA826I, ALA832I, ALA849I, ALA861I, ARG106M, ARG124I, ARG130I, ARG131I, ARG134M, ARG203I, ARG239M, ARG290M, ARG301I, ARG308I, ARG310I, ARG311M, ARG322M, ARG327M, ARG331M, ARG344M, ARG360M, ARG427I, ARG45M, ARG490I, ARG690I, ARG812I, ARG821I, ARG822I, ARG831I, ARG839I, ARG870I, ARG874I, ASN279I, ASN312I, ASN339M, ASN34M, ASN372M, ASN38M, ASN454I, ASN5I, ASN605I, ASN825I, ASN869I, ASP112M, ASP176M, ASP198I, ASP254M, ASP278I, ASP307M, ASP309M, ASP30M, ASP318M, ASP31M, ASP356M, ASP362M, ASP46M, ASP49M, ASP53M, ASP559I, ASP808I, ASP829I, ASP835I, ASP852I, ASP853I, ASP867I, GLN243M, GLN300I, GLN328M, GLN606I, GLN607I, GLN76M, GLN815I, GLN820I, GLN847I, GLN84M, GLU109M, GLU134I, GLU145M, GLU172M, GLU193I, GLU280I, GLU337M, GLU348M, GLU364M, GLU365M, GLU371M, GLU387M, GLU40M, GLU471I, GLU475I, GLU478I, GLU47M, GLU58M, GLU618I, GLU61M, GLU685I, GLU68M, GLU804I, GLU80M, GLU833I, GLU844I, GLU873I, GLU92I, GLY103M, GLY12I, GLY196I, GLY304I, GLY305M, GLY307I, GLY311I, GLY315I, GLY324M, GLY330M, GLY333M, GLY336M, GLY361M, GLY368M, GLY376M, GLY382M, GLY384M, GLY492I, GLY62M, GLY67M, GLY689I, GLY71M, GLY79M, GLY805I, GLY817I, GLY82M, GLY836I, GLY843I, GLY851I, GLY854I, GLY85I, GLY863I, GLY877I, GLY8I, HIS312M, HIS332M, HIS353M, HIS377M, HIS426I, HIS83I, HIS862I, HIS89I, ILE108M, ILE13I, ILE194I, ILE241M, ILE28M, ILE294M, ILE297M, ILE310M, ILE313M, ILE316M, ILE325M, ILE329M, ILE36M, ILE373M, ILE374M, ILE375M, ILE379M, ILE41M, ILE428I, ILE479I, ILE48M, ILE495I, ILE51M, ILE56M, ILE64M, ILE687I, ILE6I, ILE70M, ILE72M, ILE824I, ILE871I, ILE90I, ILE9I, LEU102M, LEU104M, LEU107M, LEU14I, LEU195I, LEU24M, LEU252M, LEU298I, LEU301M, LEU302I, LEU306M, LEU313I, LEU314M, LEU315M, LEU32M, LEU342M, LEU354M, LEU355M, LEU35M, LEU37M, LEU381M, LEU425I, LEU54M, LEU63M, LEU823I, LEU827I, LEU830I, LEU841I, LEU86I, LYS10I, LYS122I, LYS123I, LYS177M, LYS27M, LYS303I, LYS305I, LYS316I, LYS338M, LYS33M, LYS352M, LYS367M, LYS380M, LYS39M, LYS50M, LYS57M, LYS617I, LYS7I, LYS864I, LYS879I, LYS88I, MET173M, MET207I, MET320M, MET385M, MET430I, MET819I, MET858I, MET85M, PHE11I, PHE277I, PHE309I, PHE347M, PHE366M, PHE52M, PHE856I, PHE872I, PHE93I, PRO105M, PRO126I, PRO199I, PRO204I, PRO25M, PRO282I, PRO378M, PRO423I, PRO451I, PRO452I, PRO489I, PRO608I, PRO66M, PRO688I, PRO81M, PRO857I, SER127I, SER202I, SER314I, SER340M, SER424I, SER429I, SER60M, SER77M, SER816I, SER828I, SER840I, SER860I, THR119M, THR201I, THR321M, THR323M, THR335M, THR350M, THR383M, THR44M, THR488I, THR809I, THR813I, THR837I, THR83M, THR865I, THR86M, TRP125I, TRP614I, TRP878I, TYR197I, TYR453I, TYR491I, TYR59M, TYR818I, TYR834I, TYR842I, TYR850I, TYR859I, VAL111M, VAL192I, VAL242M, VAL29M, VAL308M, VAL319M, VAL334M, VAL341M, VAL349M, VAL351M, VAL363M, VAL369M, VAL370M, VAL386M, VAL43M, VAL73M, VAL78M, VAL838I, VAL845I, VAL846I, VAL848I, VAL84I, VAL855I, VAL866I, VAL868I, VAL875I, VAL876I, VAL87I
• I-J: ALA1003J, ALA1005J, ALA1042J, ALA1096J, ALA274I, ALA299I, ALA339J, ALA344I, ALA432I, ALA442J, ALA455I, ALA471J, ALA472I, ALA474I, ALA476I, ALA498I, ALA499I, ALA618J, ALA624J, ALA627J, ALA646J, ALA652J, ALA725I, ALA725J, ALA729I, ALA733I, ALA744I, ALA745I, ALA799I, ALA800I, ALA810I, ALA914J, ALA929J, ALA966J, ALA998J, ARG1004J, ARG1006J, ARG1014J, ARG1020J, ARG1022J, ARG1027J, ARG1033J, ARG1048J, ARG1055J, ARG10J, ARG1112J, ARG203I, ARG20I, ARG220I, ARG301I, ARG308I, ARG310I, ARG317I, ARG323I, ARG329J, ARG330J, ARG352I, ARG385I, ARG389I, ARG421I, ARG427I, ARG436I, ARG443J, ARG444I, ARG452J, ARG48I, ARG577J, ARG633I, ARG637I, ARG647I, ARG665J, ARG734I, ARG742J, ARG753I, ARG759I, ARG764I, ARG781J, ARG787I, ARG803I, ARG812I, ARG821I, ARG822I, ARG831I, ARG833J, ARG918J, ARG974J, ARG982J, ASN1052J, ASN1073J, ASN1087J, ASN312I, ASN331I, ASN376I, ASN420I, ASN439J, ASN446I, ASN463I, ASN463J, ASN469J, ASN485I, ASN5I, ASN605I, ASN623J, ASN63I, ASN661J, ASN666J, ASN67I, ASN723I, ASN733J, ASN739I, ASN825I, ASN911J, ASP1034J, ASP1047J, ASP1051J, ASP1054J, ASP1062J, ASP1071J, ASP1117J, ASP233I, ASP278I, ASP319I, ASP329I, ASP333J, ASP334J, ASP336J, ASP444J, ASP456I, ASP458I, ASP460I, ASP501I, ASP561J, ASP617J, ASP632J, ASP636J, ASP650I, ASP736J, ASP808I, ASP829I, ASP876J, ASP896J, ASP965J, ASP972J, ASP999J, CYS1035J, CYS1061J, CYS1064J, CYS1079J, CYS450I, CYS454J, CYS58I, CYS61I, CYS68I, GLN1010J, GLN1015J, GLN1063J, GLN1102J, GLN300I, GLN422I, GLN437J, GLN449J, GLN468I, GLN500I, GLN523I, GLN642I, GLN662J, GLN742I, GLN750I, GLN815I, GLN820I, GLN884J, GLN923J, GLN954J, GLN977J, GLU1018J, GLU1023J, GLU1030J, GLU1032J, GLU1103J, GLU1116J, GLU18I, GLU306I, GLU331J, GLU408I, GLU441J, GLU457J, GLU460J, GLU461I, GLU470I, GLU471I, GLU475I, GLU519I, GLU520I, GLU53I, GLU565J, GLU619J, GLU620J, GLU621J, GLU622J, GLU629J, GLU640I, GLU641J, GLU649I, GLU659J, GLU735J, GLU794I, GLU804I, GLU926J, GLU951J, GLU968J, GLY1007J, GLY1019J, GLY1024J, GLY1025J, GLY1029J, GLY1038J, GLY1040J, GLY1065J, GLY1068J, GLY12I, GLY304I, GLY307I, GLY311I, GLY315I, GLY440I, GLY447J, GLY451J, GLY459I, GLY461J, GLY465J, GLY497I, GLY505I, GLY50I, GLY526I, GLY62I, GLY643I, GLY66I, GLY70I, GLY731J, GLY732I, GLY735I, GLY73I, GLY760I, GLY789I, GLY801I, GLY802I, GLY805I, GLY817I, GLY842J, GLY85I, GLY875J, GLY886J, GLY889J, GLY8I, GLY922J, GLY927J, GLY976J, HIS1002J, HIS1082J, HIS337J, HIS426I, HIS446J, HIS465I, HIS557J, HIS567J, HIS637J, HIS639J, HIS660J, HIS71I, HIS768I, HIS798I, HIS83I, HIS841J, HIS913J, HIS995J, ILE1011J, ILE1037J, ILE1058J, ILE1067J, ILE1081J, ILE1101J, ILE1108J, ILE1109J, ILE13I, ILE19I, ILE208I, ILE217I, ILE219I, ILE326I, ILE332I, ILE342I, ILE343I, ILE379I, ILE416I, ILE428I, ILE473I, ILE479I, ILE503I, ILE52I, ILE558J, ILE563J, ILE636I, ILE647J, ILE655J, ILE6I, ILE738J, ILE739J, ILE740I, ILE757I, ILE824I, ILE871J, ILE874J, ILE888J, ILE892J, ILE909J, ILE924J, ILE928J, ILE950J, ILE979J, ILE983J, ILE9I, LEU1001J, LEU1012J, LEU1026J, LEU1036J, LEU1044J, LEU1045J, LEU1049J, LEU1050J, LEU1088J, LEU1099J, LEU1100J, LEU1104J, LEU1113J, LEU1115J, LEU14I, LEU209I, LEU212I, LEU235I, LEU239I, LEU298I, LEU302I, LEU313I, LEU347I, LEU411I, LEU418I, LEU425I, LEU438I, LEU441I, LEU445I, LEU445J, LEU447I, LEU448I, LEU464I, LEU466J, LEU481I, LEU49I, LEU508I, LEU515I, LEU516I, LEU579J, LEU616J, LEU628J, LEU640J, LEU641I, LEU648I, LEU648J, LEU65I, LEU738I, LEU747I, LEU766I, LEU77I, LEU790I, LEU795I, LEU806I, LEU830I, LEU86I, LEU891J, LEU910J, LEU915J, LEU921J, LEU963J, LEU993J, LYS1000J, LYS1046J, LYS1072J, LYS1074J, LYS1076J, LYS1098J, LYS10I, LYS1118J, LYS178J, LYS21I, LYS238I, LYS305I, LYS316I, LYS345I, LYS439I, LYS468J, LYS477I, LYS484I, LYS4I, LYS658I, LYS758I, LYS770I, LYS791I, LYS7I, LYS877J, LYS885J, LYS978J, LYS980J, MET1031J, MET1043J, MET1057J, MET1105J, MET1107J, MET207I, MET22I, MET430I, MET431I, MET453J, MET462I, MET480I, MET646I, MET672J, MET727J, MET728I, MET734J, MET743I, MET746I, MET762I, MET819I, MET844J, MET858I, MET890J, MET919J, MET925J, MET996J, PHE1028J, PHE1039J, PHE1089J, PHE1097J, PHE11I, PHE277I, PHE309I, PHE320I, PHE419I, PHE440J, PHE443I, PHE456J, PHE457I, PHE632I, PHE638I, PHE644I, PHE724I, PHE729J, PHE72I, PHE769I, PHE786I, PHE796I, PHE797I, PHE856I, PHE878J, PHE945J, PHE985J, PRO1008J, PRO1016J, PRO1080J, PRO1090J, PRO1111J, PRO16I, PRO213I, PRO215I, PRO216I, PRO221I, PRO328I, PRO330I, PRO340I, PRO350I, PRO423I, PRO438J, PRO451I, PRO455J, PRO459J, PRO462J, PRO467I, PRO489I, PRO54I, PRO59I, PRO645J, PRO658J, PRO664J, PRO69I, PRO767I, PRO771I, PRO792I, PRO898J, PRO912J, PRO916J, PRO944J, PRO949J, PRO964J, SER1053J, SER1094J, SER1106J, SER1110J, SER15I, SER202I, SER222I, SER23I, SER314I, SER321I, SER322I, SER327I, SER424I, SER429I, SER464J, SER469I, SER504I, SER644J, SER652I, SER663J, SER728J, SER736I, SER737J, SER784I, SER785I, SER816I, SER828I, SER917J, SER981J, THR1013J, THR1017J, THR1041J, THR1056J, THR1092J, THR200I, THR201I, THR210I, THR218I, THR297I, THR324I, THR346I, THR348I, THR442I, THR448J, THR458J, THR513I, THR514I, THR517I, THR560J, THR60I, THR638J, THR645I, THR64I, THR667J, THR730J, THR731I, THR741I, THR763I, THR765I, THR788I, THR793I, THR809I, THR813I, THR873J, THR920J, THR967J, THR975J, TRP1069J, TRP206I, TRP450J, TRP643J, TYR1059J, TYR1066J, TYR1070J, TYR1095J, TYR276I, TYR338J, TYR377I, TYR390I, TYR453I, TYR502I, TYR545I, TYR625J, TYR657J, TYR668J, TYR726I, TYR732J, TYR761I, TYR772I, TYR788J, TYR818I, TYR946J, TYR962J, TYR984J, VAL1009J, VAL1060J, VAL1078J, VAL1091J, VAL1093J, VAL1114J, VAL1119J, VAL211I, VAL214I, VAL24I, VAL273I, VAL318I, VAL325I, VAL349I, VAL378I, VAL417I, VAL466I, VAL467J, VAL482I, VAL559J, VAL626J, VAL639I, VAL651I, VAL726J, VAL727I, VAL737I, VAL752I, VAL807I, VAL811I, VAL84I, VAL887J, VAL970J, VAL997J
• I-O: ARG211O, ARG218O, ARG543I, ARG647I, ASN26O, ASP224O, ASP650I, CYS206O, GLN523I, GLU207O, GLU208O, GLU223O, GLU23O, GLU519I, GLU649I, LEU22O, PHE724I, PRO21O, TYR212O, TYR226O
• I-Q: ARG352I, ASN16Q, ASN5I, ASP63Q, GLU470I, GLU471I, GLU475I, GLY62Q, GLY64Q, PHE61Q, PRO15Q, PRO403I, SER469I, VAL60Q
• I-S: ALA538I, ALA541I, ARG20S, ARG543I, ARG573I, ARG63S, ASN25S, ASN47S, ASN723I, ASN88S, ASP41S, ASP44S, ASP579I, ASP583I, ASP720I, CYS580I, CYS72S, GLN642I, GLU110S, GLU536I, GLU544I, GLU578I, GLU595I, GLU80S, GLY21S, GLY535I, HIS582I, HIS68S, HIS74S, ILE42S, ILE43S, ILE46S, ILE48S, ILE539I, LEU23S, LEU26S, LEU508I, LEU515I, LEU534I, LEU540I, LYS24S, LYS512I, LYS549I, LYS82S, LYS879I, LYS91S, MET28S, PHE49S, PHE722I, PHE724I, PRO537I, PRO542I, PRO572I, PRO581I, PRO64S, PRO721I, SER22S, SER27S, SER45S, SER584I, THR513I, THR514I, THR547I, THR79S, TYR507I, TYR545I, VAL511I, VAL568I, VAL597I, VAL727I
• I-T: ARG67T, ASP835I, ASP852I, GLN41T, GLU34T, GLU40T, LYS122I, TYR842I
• I-U: ARG29U, ARG34U, ASN16U, ASP835I, GLU471I, GLU475I, GLU478I, GLU66U, LYS477I, LYS484I
• I-V: ARG33V, ARG34V, ARG436I, ARG444I, ASP329I, ASP529I, GLU14V, GLU519I, HIS47V, LYS56V, LYS7V, VAL527I
• I-Z: ASP70Z, GLU112I, GLU69Z, GLU76Z, LYS122I, LYS66Z, LYS73Z
• M-J: ALA1042J, ALA1096J, ALA161M, ALA217M, ALA218M, ALA343M, ALA345M, ALA346M, ALA357M, ALA358M, ALA359M, ALA69M, ALA74M, ALA75M, ARG1033J, ARG1048J, ARG1055J, ARG1112J, ARG223M, ASN182J, ASN228M, ASN250J, ASN372M, ASP1034J, ASP1047J, ASP1051J, ASP1054J, ASP159M, ASP356M, ASP362M, CYS1035J, GLN249J, GLN258J, GLN76M, GLU1030J, GLU1032J, GLU1103J, GLU1116J, GLU251J, GLU257J, GLU364M, GLU365M, GLU371M, GLU68M, GLY1038J, GLY1040J, GLY208J, GLY361M, GLY376M, GLY382M, GLY384M, GLY67M, GLY71M, GLY79M, HIS211J, HIS353M, HIS377M, ILE1037J, ILE1058J, ILE1101J, ILE1108J, ILE1109J, ILE158M, ILE160M, ILE183J, ILE216M, ILE373M, ILE374M, ILE375M, ILE379M, ILE70M, ILE72M, LEU1036J, LEU1044J, LEU1045J, LEU1049J, LEU1050J, LEU1100J, LEU1104J, LEU1113J, LEU219M, LEU252J, LEU256J, LEU327J, LEU342M, LEU354M, LEU355M, LEU381M, LYS1046J, LYS1098J, LYS221M, LYS352M, LYS380M, MET1031J, MET1043J, MET1107J, MET385M, PHE1028J, PHE1039J, PHE1097J, PHE210J, PHE220M, PHE253J, PHE347M, PHE366M, PRO1111J, PRO254J, PRO378M, SER1094J, SER1110J, SER154M, SER155M, SER157M, SER255J, THR1041J, THR1092J, THR156M, THR179J, THR184J, THR209J, THR350M, THR383M, THR83M, TYR326J, VAL1091J, VAL1093J, VAL1114J, VAL341M, VAL351M, VAL363M, VAL369M, VAL370M, VAL73M
• M-Q: ALA65Q, ARG12Q, ARG391M, ARG395M, ASN23Q, GLU17Q, GLU387M, GLU55Q, GLU56Q, GLU69Q, GLY19Q, GLY382M, GLY384M, GLY57Q, GLY62Q, GLY64Q, HIS377M, HIS68Q, ILE13Q, ILE379M, ILE393M, ILE58Q, LEU22Q, LEU381M, LEU388M, LEU394M, LEU59Q, LYS20Q, LYS380M, MET385M, MET390M, PHE18Q, PHE61Q, PRO15Q, PRO21Q, PRO378M, PRO392M, SER54Q, THR383M, THR389M, THR66Q, TYR67Q, VAL386M, VAL60Q
• M-T: ARG290M, ARG322M, ARG67T, ARG79T, ASP268M, ASP30M, ASP49T, GLU281M, GLU282M, GLU287M, GLU291M, GLU74T, HIS14T, HIS20T, LYS271M
• M-U: ARG29U, ARG34U, ARG391M, ARG39U, ARG79U, ARG81U, ASP30M, GLU31U, GLU387M, GLU68M, HIS14U, THR389M, THR77U
• M-Z: ARG327M, ARG81Z, ARG82Z, HIS332M
• J-O: ALA154O, ALA27O, ALA31O, ALA59O, ALA63O, ARG12O, ARG165O, ARG211O, ARG29O, ARG30O, ARG61O, ARG742J, ARG747J, ARG751J, ARG865J, ARG867J, ARG870J, ARG959J, ARG974J, ARG982J, ASN181O, ASN26O, ASN49O, ASN50O, ASN741J, ASP55O, ASP848J, ASP868J, ASP896J, ASP965J, ASP972J, CYS183O, CYS203O, CYS206O, CYS209O, GLN137O, GLN685J, GLN894J, GLN977J, GLU152O, GLU185O, GLU207O, GLU208O, GLU229O, GLU231O, GLU23O, GLU48O, GLU56O, GLU746J, GLU801J, GLU803J, GLU968J, GLY150O, GLY186O, GLY748J, GLY845J, GLY903J, GLY961J, GLY973J, GLY976J, HIS153O, HIS60O, HIS696J, ILE130O, ILE157O, ILE219O, ILE227O, ILE57O, ILE846J, ILE871J, ILE892J, ILE957J, ILE979J, ILE983J, LEU161O, LEU201O, LEU205O, LEU210O, LEU228O, LEU22O, LEU34O, LEU53O, LEU58O, LEU64O, LEU694J, LEU695J, LEU869J, LEU958J, LEU963J, LYS151O, LYS155O, LYS178O, LYS902J, LYS978J, LYS980J, MET33O, MET749J, MET897J, PHE156O, PHE221O, PHE24O, PHE46O, PHE755J, PRO129O, PRO158O, PRO184O, PRO52O, PRO800J, PRO893J, PRO898J, PRO964J, SER160O, SER162O, SER202O, SER32O, SER51O, SER743J, SER744J, SER752J, SER981J, THR204O, THR753J, THR900J, THR967J, THR975J, TYR166O, TYR167O, TYR212O, TYR226O, TYR35O, TYR54O, TYR684J, TYR697J, TYR899J, TYR960J, TYR962J, TYR971J, VAL159O, VAL163O, VAL164O, VAL180O, VAL182O, VAL233O, VAL25O, VAL745J, VAL847J, VAL895J, VAL901J, VAL904J, VAL905J, VAL969J, VAL970J
• J-Q: ALA1042J, ARG12Q, ASN1087J, ASP1084J, ASP1117J, ASP63Q, GLN33Q, GLU69Q, GLY1040J, GLY1083J, GLY62Q, ILE10Q, ILE58Q, LEU1044J, LEU59Q, LYS1046J, LYS1085J, LYS1118J, MET1043J, PHE61Q, SER9Q, THR1041J, THR152Q, TYR1077J, TYR34Q, TYR67Q, VAL1119J, VAL11Q, VAL153Q, VAL60Q
• J-R: ASN1087J, ASP1117J, LYS1118J, MET1R, PHE1089J, SER2R, SER3R, TYR5R, VAL1119J, VAL4R
• J-S: ASN25S, LYS24S, LYS980J, SER45S, SER981J
• J-V: ARG974J, ASP21V, ASP896J, ASP972J, HIS22V
• J-W: ARG42W, ARG46W, ARG47W, ARG6W, ARG700J, ARG716J, ARG747J, ASP136J, ASP144J, ASP54W, ASP907J, GLU58W, GLU968J, GLY930J, HIS52W, HIS61W, HIS696J, LEU935J, LYS146J, LYS41W, LYS902J, MET1W, PHE8W, SER51W, THR9W
• J-X: ARG38X, ARG751J, ARG88J, GLU140J, GLU793J, GLU801J, GLU803J, GLU84J, GLU854J, ILE34X, ILE48X, ILE852J, LYS11X, LYS32X, LYS39X, LYS43X
• O-S: ARG211O, ARG218O, ASN47S, ASP44S, LYS24S, SER45S
• O-V: ARG30O, ARG33V, ARG34V, ARG77V, ASP21V, ASP51V, GLU20V, GLU239O, GLU23O, GLU254O, GLU257O, GLU2V, GLU74V, GLU86V, HIS22V, ILE3O, LYS151O, LYS252O, LYS259O, LYS92V, SER2O, THR23V, TYR20O, TYR35O
• O-W: ARG12O, ARG6W, ASP127O, ASP16W, GLU231O, LEU64O, LYS155O, LYS17W, LYS41W
• O-X: ALA47X, ARG38X, ASP42O, ASP43O, ASP55O, GLU48O, LYS155O, LYS43X, LYS46X, PHE46O
• Q-R: ALA144Q, ALA17R, ALA47Q, ALA70R, ALA73R, ALA7Q, ARG143Q, ARG145Q, ARG26R, ARG31Q, ARG36R, ARG69R, ARG84R, ARG8Q, ASN100Q, ASN32R, ASN42R, ASN50Q, ASP105Q, ASP23R, ASP39R, ASP41Q, ASP67R, ASP73Q, ASP81R, GLN166Q, GLN33Q, GLN35Q, GLN35R, GLN53R, GLN82Q, GLN91Q, GLU36Q, GLU45R, GLU66R, GLU69Q, GLU71Q, GLU82R, GLU83Q, GLU86Q, GLU88Q, GLU8R, GLU9R, GLY102Q, GLY28R, GLY29R, GLY87Q, HIS10R, ILE10Q, ILE12R, ILE175Q, ILE38Q, ILE48Q, ILE5Q, ILE6R, ILE71R, ILE75Q, ILE75R, ILE86R, LEU101Q, LEU169Q, LEU172Q, LEU20R, LEU21R, LEU27Q, LEU30Q, LEU33R, LEU34R, LEU39Q, LEU41R, LEU42Q, LEU44Q, LEU46Q, LEU49Q, LEU4Q, LEU72R, LEU87R, LEU90Q, LYS141Q, LYS179Q, LYS180Q, LYS18R, LYS19R, LYS37Q, LYS3Q, LYS40Q, LYS46R, LYS52Q, LYS6Q, MET104Q, MET1Q, MET1R, MET74Q, MET89R, PHE72Q, PRO103Q, PRO13R, PRO158Q, PRO167Q, PRO77R, PRO79Q, SER27R, SER2R, SER30R, SER31R, SER3R, SER43R, SER74R, SER80R, SER85R, SER9Q, THR176Q, THR178Q, THR22R, THR37R, THR76Q, THR78R, THR79R, TYR11R, TYR14R, TYR168Q, TYR2Q, TYR34Q, TYR38R, TYR40R, TYR5R, TYR77Q, VAL11Q, VAL142Q, VAL146Q, VAL153Q, VAL16R, VAL24R, VAL44R, VAL45Q, VAL4R, VAL68R, VAL70Q, VAL78Q, VAL7R, VAL80Q, VAL81Q, VAL83R, VAL84Q, VAL85Q, VAL88R, VAL99Q
• T-U: ARG64T, ASP12U, GLU17U, GLU27T, GLU34T, GLU74T, HIS14U, LYS30T, LYS86U, TYR78T
• T-Z: ARG38T, ARG46T, ARG78Z, ASP70Z, GLU40T, GLU62Z, GLU63Z, LYS33T, LYS66Z
• W-X: ARG64W, LYS8X