3HHP

malate dehydrogenase open conformation

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 175
  • Norm. En. per Res.: -3.5737
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-97.6696	-31.1311	-496.603	-625.4037	175	13	14	19550	3	24	25
A-C	0.0	-3.6544	-47.7666	-51.421	33	7	0	1865	0	9	10
A-D	0.0	0.0	-23.5201	-23.5201	27	4	0	1157	0	2	2
B-D	0.0	-3.975	-48.1898	-52.1648	29	6	0	1849	0	9	9
C-D	-86.8656	-34.6203	-482.758	-604.2438	174	13	14	19182	4	24	26

Interface residues

• A-B: ALA159A, ALA159B, ALA15A, ALA15B, ALA17A, ALA17B, ALA209A, ALA209B, ALA216A, ALA216B, ALA218A, ALA218B, ALA223A, ALA223B, ALA230A, ALA230B, ALA232A, ALA232B, ALA36A, ALA36B, ALA43A, ALA43B, ALA52A, ALA52B, ALA8A, ALA8B, ALA9A, ALA9B, ARG153A, ARG153B, ARG205A, ARG205B, ARG233A, ARG233B, ASN155A, ASN155B, ASN208A, ASN208B, ASP150A, ASP150B, ASP45A, ASP45B, GLN14A, GLN14B, GLN165A, GLN165B, GLN229A, GLN229B, GLN23A, GLN23B, GLU160A, GLU160B, GLU168A, GLU168B, GLU170A, GLU170B, GLU212A, GLU212B, GLU215A, GLU215B, GLY10A, GLY10B, GLY11A, GLY11B, GLY13A, GLY13B, GLY167A, GLY167B, GLY210A, GLY210B, GLY219A, GLY219B, GLY220A, GLY220B, GLY221A, GLY221B, GLY228A, GLY228B, GLY27A, GLY27B, GLY41A, GLY41B, GLY57B, HIS48A, HIS48B, ILE12A, ILE12B, ILE151A, ILE151B, ILE152A, ILE152B, ILE206A, ILE206B, ILE49A, ILE49B, ILE55A, ILE55B, LEU149A, LEU149B, LEU16A, LEU16B, LEU18A, LEU18B, LEU19A, LEU19B, LEU20B, LEU225A, LEU225B, LEU32A, LEU32B, LEU46A, LEU46B, LYS164A, LYS164B, LYS217A, LYS217B, LYS21A, LYS21B, LYS54A, LYS54B, MET227A, MET227B, PHE157A, PHE157B, PRO166A, PRO166B, PRO37A, PRO37B, PRO40A, PRO40B, PRO50A, PRO50B, SER154A, SER154B, SER222A, SER222B, SER226A, SER226B, SER26A, SER26B, SER47A, SER47B, SER59B, THR148A, THR148B, THR156A, THR156B, THR211A, THR211B, THR224A, THR224B, THR22A, THR22B, THR39A, THR39B, THR51A, THR51B, VAL158A, VAL158B, VAL169A, VAL169B, VAL171A, VAL171B, VAL213A, VAL213B, VAL214A, VAL214B, VAL38A, VAL38B, VAL42A, VAL42B, VAL44A, VAL44B, VAL53A, VAL53B
• A-C: ALA159C, ALA241A, ARG278A, GLN165C, GLN246A, GLN246C, GLU168C, GLU245A, GLU276A, GLU277A, GLY163C, GLY167C, GLY191A, GLY191C, GLY244A, GLY247A, GLY247C, GLY271A, LEU269A, LEU270A, LYS162C, LYS164C, LYS272A, LYS279A, PRO166C, PRO190A, PRO190C, SER280A, VAL169C, VAL189C, VAL192C, VAL248A, VAL249A
• A-D: ALA52A, ALA52D, GLN243A, GLN243D, GLN246A, GLN246D, GLU245A, GLU245D, GLY244A, GLY244D, GLY247A, GLY247D, GLY27A, GLY27D, LYS272A, LYS272D, PRO25A, PRO25D, PRO50A, PRO50D, SER26A, SER26D, SER28D, THR51A, THR51D, VAL53A, VAL53D
• B-D: ALA241D, ARG278D, GLN165B, GLN246B, GLN246D, GLU168B, GLU245D, GLU276D, GLU277D, GLY163B, GLY167B, GLY191B, GLY191D, GLY244D, GLY247B, GLY247D, GLY271D, LEU269D, LEU270D, LYS164B, LYS272D, LYS279D, PRO166B, PRO190B, PRO190D, SER280D, VAL169B, VAL248D, VAL249D
• C-D: ALA159C, ALA159D, ALA15C, ALA15D, ALA17C, ALA17D, ALA209C, ALA209D, ALA216C, ALA216D, ALA218C, ALA218D, ALA223C, ALA223D, ALA230C, ALA230D, ALA232C, ALA232D, ALA36C, ALA36D, ALA43C, ALA43D, ALA52C, ALA52D, ALA8C, ALA8D, ALA9C, ALA9D, ARG153C, ARG153D, ARG205C, ARG205D, ARG233C, ARG233D, ASN155C, ASN155D, ASN208C, ASN208D, ASP150C, ASP150D, ASP45C, ASP45D, GLN14C, GLN14D, GLN165C, GLN165D, GLN229C, GLN229D, GLN23C, GLN23D, GLU160C, GLU160D, GLU168C, GLU168D, GLU170C, GLU170D, GLU212C, GLU212D, GLU215C, GLU215D, GLY10C, GLY10D, GLY11C, GLY11D, GLY13C, GLY13D, GLY167C, GLY167D, GLY210C, GLY210D, GLY219C, GLY219D, GLY220C, GLY220D, GLY221C, GLY221D, GLY228C, GLY228D, GLY27C, GLY27D, GLY41C, GLY41D, HIS48C, HIS48D, ILE12C, ILE12D, ILE151C, ILE151D, ILE152C, ILE152D, ILE206C, ILE206D, ILE49C, ILE49D, ILE55C, ILE55D, LEU149C, LEU149D, LEU16C, LEU16D, LEU18C, LEU18D, LEU19C, LEU19D, LEU225C, LEU225D, LEU32C, LEU32D, LEU46C, LEU46D, LYS164C, LYS164D, LYS217C, LYS217D, LYS21C, LYS21D, LYS54C, LYS54D, LYS56C, LYS56D, MET227C, MET227D, PHE157C, PHE157D, PRO166C, PRO166D, PRO37C, PRO37D, PRO40C, PRO40D, PRO50C, PRO50D, SER154C, SER154D, SER222C, SER222D, SER226C, SER226D, SER26C, SER26D, SER47C, SER47D, SER59D, THR148C, THR148D, THR156C, THR156D, THR211C, THR211D, THR224C, THR224D, THR22C, THR22D, THR39C, THR39D, THR51C, THR51D, VAL158C, VAL158D, VAL169C, VAL169D, VAL171C, VAL213C, VAL213D, VAL214C, VAL214D, VAL38C, VAL38D, VAL42C, VAL42D, VAL44C, VAL44D, VAL53C, VAL53D