3HHC

interferon-lambda is functionally an interferon but structurally related to the il-10 family

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 25
  • Norm. En. per Res.: -4.8605
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-49.2097	-41.5712	-90.7809	39	2	1	1889	3	16	25
A-C	-21.579	-67.6728	502.851	413.5992	90	18	3	11178	1	52	47
A-D	-6.3856	-39.7676	-75.3594	-121.5126	25	4	0	2667	4	17	6
B-C	-15.838	-39.2287	-90.3747	-145.4414	35	6	0	3131	3	17	10
B-D	-41.8742	-74.8967	-278.395	-395.1659	92	21	3	11885	2	53	50
C-D	0.0	0.0	-0.289	-0.289	4	0	0	71	0	0	1

Interface residues

• A-B: ALA19A, ALA19B, ALA23A, ALA23B, ALA26A, ALA26B, ALA81A, ALA81B, ARG22A, ARG22B, ASP25A, ASP25B, ASP84A, ASP84B, ASP87A, ASP87B, GLN15A, GLN15B, GLN18A, GLN18B, GLN88A, GLN88B, GLU29A, GLU29B, GLY83A, GLY83B, HIS91A, HIS91B, LEU82A, LEU82B, LEU86A, LEU86B, LYS21A, LYS21B, PRO80A, PRO80B, PRO89A, VAL85A, VAL85B
• A-C: ALA139A, ALA139C, ALA23A, ALA26A, ALA26C, ARG147A, ARG147C, ARG151A, ARG151C, ARG22A, ARG22C, ARG39A, ARG39C, ARG41A, ARG41C, ARG45A, ARG45C, ASN144A, ASN144C, ASP25A, ASP25C, ASP35A, ASP35C, ASP79A, ASP79C, CYS136A, CYS136C, CYS36A, CYS36C, CYS38A, CYS38C, GLN18A, GLN18C, GLU132A, GLU132C, GLU138A, GLU138C, GLU28A, GLU28C, GLU29A, GLU29C, GLY135A, GLY135C, LEU137A, LEU137C, LEU145A, LEU145C, LEU27A, LEU27C, LEU31A, LEU31C, LEU32A, LEU32C, LEU33A, LEU33C, LEU42A, LEU42C, LEU82A, LYS21A, LYS21C, LYS24A, LYS24C, LYS34A, LYS34C, LYS37A, LYS37C, PHE143A, PHE143C, PHE146A, PHE146C, PHE43A, PHE43C, PRO44A, PRO44C, SER140A, SER140C, SER30A, SER30C, SER40A, SER40C, THR142A, THR142C, THR150A, THR150C, THR46A, THR46C, TRP47A, VAL141A, VAL141C, VAL85A
• A-D: ALA74A, ALA76A, ALA81A, ARG147D, ARG151D, ARG45D, ARG50D, ASP48D, ASP77A, ASP79A, ASP84A, ASP87A, GLN51D, GLY83A, LEU33A, LEU49D, LEU82A, PRO44D, PRO80A, SER30A, THR46D, THR75A, THR78A, TRP47D, VAL85A
• B-C: ALA74B, ALA76B, ALA81B, ARG117C, ARG147C, ARG151C, ARG41C, ARG45C, ARG50C, ARG57C, ASP152C, ASP48C, ASP77B, ASP79B, ASP84B, ASP87B, CYS162C, GLN51C, GLU73B, GLY83B, LEU33B, LEU49C, LEU52C, LEU82B, LYS34B, PRO134B, PRO44C, PRO80B, SER30B, THR46C, THR75B, THR78B, TRP47C, VAL163C, VAL85B
• B-D: ALA139B, ALA139D, ALA23B, ALA23D, ALA26B, ALA26D, ALA81B, ARG147B, ARG147D, ARG151B, ARG151D, ARG22B, ARG22D, ARG39B, ARG39D, ARG41B, ARG41D, ARG45B, ARG45D, ASN144B, ASN144D, ASP25B, ASP25D, ASP35B, ASP35D, ASP79B, CYS136B, CYS136D, CYS36B, CYS36D, CYS38B, CYS38D, GLN18B, GLN18D, GLU132B, GLU138B, GLU138D, GLU28B, GLU28D, GLU29B, GLU29D, GLY135B, GLY135D, LEU137B, LEU137D, LEU145B, LEU27B, LEU27D, LEU31B, LEU31D, LEU32B, LEU32D, LEU33B, LEU33D, LEU42B, LEU42D, LEU82B, LEU82D, LYS21B, LYS21D, LYS24B, LYS24D, LYS34B, LYS34D, LYS37B, LYS37D, PHE143B, PHE143D, PHE146B, PHE146D, PHE43B, PHE43D, PRO44B, PRO44D, SER140B, SER140D, SER30B, SER30D, SER40B, SER40D, THR142B, THR142D, THR150B, THR150D, THR46B, THR46D, TRP47B, TRP47D, VAL141B, VAL141D, VAL85B, VAL85D
• C-D: ARG41C, ARG41D, THR46C, THR46D