3HGQ

structural and functional studies of the yeast class ii hda1 hdac complex

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 89
  • Norm. En. per Res.: -3.0849
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-3.104	-68.3514	-190.512	-261.9675	89	6	5	7395	7	29	34
B-C	-28.9395	-19.9991	-62.9112	-111.8497	51	16	0	3438	4	15	15
B-D	0.0	-2.16	-1.5504	-3.7104	15	0	0	331	0	5	8
C-D	-4.9964	-81.8084	-187.751	-274.5558	89	12	5	7810	8	29	29

Interface residues

• A-B: ALA110A, ALA110B, ARG103A, ARG103B, ARG274A, ARG274B, ARG276A, ARG276B, ARG285A, ARG285B, ASN112A, ASN112B, ASP104A, ASP104B, ASP275A, ASP275B, ASP46A, ASP46B, ASP93A, ASP93B, GLN290A, GLN290B, GLN41A, GLN41B, GLN47A, GLN47B, GLU111A, GLU111B, GLU329A, GLU43A, GLU43B, GLY114A, GLY114B, GLY278A, HIS108A, HIS108B, HIS87A, HIS87B, HIS94A, HIS94B, ILE287A, ILE92A, ILE92B, LEU109A, LEU109B, LEU273A, LEU273B, LEU277A, LEU277B, LEU39A, LEU39B, LEU44A, LEU44B, LYS42A, LYS42B, LYS98B, PRO286A, PRO286B, PRO88A, PRO88B, PRO97A, PRO97B, SER113A, SER113B, SER117A, SER117B, SER289A, SER289B, SER38A, SER38B, SER50A, SER50B, THR102A, THR102B, THR279A, THR279B, THR328A, THR328B, THR45A, THR45B, TYR288A, TYR40A, TYR40B, TYR89A, TYR89B, TYR95A, TYR95B, VAL49A, VAL49B
• B-C: ARG276B, ARG276C, ARG285C, ARG324B, ARG324C, ARG58B, ASN242C, ASP275B, ASP275C, ASP283C, ASP310C, ASP321B, ASP321C, GLN316B, GLN316C, GLU323B, GLU61B, HIS246C, ILE241C, ILE272B, ILE287C, ILE311C, LEU273B, LEU273C, LEU280C, LEU284C, LEU314B, LEU314C, LEU326B, LEU327B, LEU57B, LYS315B, LYS315C, PHE250C, PHE60B, PRO281C, PRO282C, PRO286C, PRO309C, PRO313C, SER319B, THR279C, THR318B, THR328B, THR62B, TRP32C, TYR312C, TYR317B, TYR317C, TYR53B, VAL322B
• B-D: ARG103D, GLN316B, GLU261B, GLU264B, HIS64B, ILE101D, LYS254B, LYS315B, LYS98D, PHE255B, SER319B, SER63B, SER99D, THR102D, THR318B
• C-D: ALA110C, ALA110D, ARG103C, ARG103D, ARG274C, ARG274D, ARG276C, ARG276D, ARG285C, ARG285D, ASN112C, ASN112D, ASP104C, ASP104D, ASP275C, ASP275D, ASP46C, ASP46D, ASP93C, ASP93D, GLN290C, GLN290D, GLN41C, GLN41D, GLN47C, GLN47D, GLU111C, GLU111D, GLU43C, GLU43D, GLY114C, GLY114D, GLY278C, GLY278D, HIS108C, HIS108D, HIS87C, HIS87D, HIS94C, HIS94D, ILE92C, ILE92D, LEU109C, LEU109D, LEU273C, LEU273D, LEU277C, LEU277D, LEU39C, LEU39D, LEU44C, LEU44D, LYS42C, LYS42D, LYS98C, LYS98D, PRO282D, PRO286C, PRO286D, PRO88C, PRO88D, PRO97C, PRO97D, SER113C, SER113D, SER117C, SER117D, SER289C, SER289D, SER38C, SER38D, SER50C, SER50D, THR102C, THR102D, THR279C, THR279D, THR328D, THR36C, THR45C, THR45D, TYR40C, TYR40D, TYR89C, TYR89D, TYR95C, TYR95D, VAL49C, VAL49D