3H9U

s-adenosyl homocysteine hydrolase (sahh) from trypanosoma brucei

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 262
  • Norm. En. per Res.: -4.7795
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-190.1229	-112.4866	-922.606	-1225.2155	263	27	31	35823	12	94	65
A-C	0.0	-6.6614	-46.0179	-52.6793	35	1	0	1783	0	11	16
B-D	-8.6769	0.0	-17.3759	-26.0528	25	1	1	812	0	3	19
C-D	-200.4015	-119.4298	-932.398	-1252.2293	262	23	30	35871	11	95	66

Interface residues

• A-B: ALA229A, ALA229B, ALA248A, ALA248B, ALA251A, ALA251B, ALA252A, ALA252B, ALA400A, ALA400B, ALA401A, ALA401B, ALA409A, ALA409B, ALA419A, ALA419B, ARG166A, ARG166B, ARG169A, ARG169B, ARG195A, ARG195B, ARG232A, ARG232B, ARG436A, ARG436B, ASN162A, ASN162B, ASN178A, ASN178B, ASN180A, ASN180B, ASN190A, ASN190B, ASN247A, ASN247B, ASN277A, ASN277B, ASN359A, ASN359B, ASN423A, ASN423B, ASP181A, ASP181B, ASP189A, ASP189B, ASP222A, ASP222B, ASP244A, ASP244B, ASP263A, ASP263B, ASP278A, ASP278B, ASP279A, ASP279B, ASP396A, ASP396B, ASP427A, ASP427B, ASP433A, ASP433B, CYS218A, CYS218B, CYS424A, CYS424B, GLN168A, GLN168B, GLN250A, GLN250B, GLN257A, GLN257B, GLN306A, GLN306B, GLN418A, GLN418B, GLU196A, GLU196B, GLU242A, GLU242B, GLU254A, GLU254B, GLU262A, GLU262B, GLU304A, GLU304B, GLU397A, GLU397B, GLU420A, GLU420B, GLY193A, GLY193B, GLY219A, GLY219B, GLY221A, GLY221B, GLY224A, GLY224B, GLY255A, GLY255B, GLY276A, GLY276B, GLY405A, GLY405B, GLY408A, GLY408B, GLY428A, GLY428B, HIS285A, HIS285B, HIS300A, HIS300B, HIS403A, HIS403B, HIS434A, HIS434B, ILE246A, ILE246B, ILE280A, ILE280B, ILE281A, ILE281B, ILE422A, ILE422B, LEU163A, LEU163B, LEU167A, LEU167B, LEU191A, LEU191B, LEU249A, LEU249B, LEU259A, LEU259B, LEU260A, LEU260B, LEU391A, LEU391B, LEU395A, LEU395B, LEU402A, LEU402B, LEU404A, LEU404B, LEU407A, LEU407B, LEU411A, LEU411B, LEU414A, LEU414B, LYS161A, LYS161B, LYS165A, LYS165B, LYS185A, LYS185B, LYS187A, LYS187B, LYS225A, LYS225B, LYS393A, LYS393B, LYS394A, LYS394B, LYS398A, LYS398B, LYS406A, LYS406B, LYS410A, LYS410B, LYS413A, LYS413B, LYS417A, LYS417B, LYS431A, LYS431B, MET253A, MET253B, MET357A, PHE188A, PHE188B, PHE301A, PHE301B, PHE355A, PHE355B, PHE390A, PHE390B, PHE430A, PHE430B, PRO245A, PRO245B, PRO353A, PRO353B, PRO392A, PRO392B, PRO425A, PRO425B, PRO429A, PRO429B, PRO432A, PRO432B, SER182A, SER182B, SER186A, SER186B, SER358A, SER358B, THR157A, THR157B, THR158A, THR158B, THR184A, THR184B, THR241A, THR241B, THR275A, THR275B, THR282A, THR282B, THR303A, THR303B, THR412A, THR412B, THR415A, THR415B, TYR164A, TYR164B, TYR192A, TYR192B, TYR220A, TYR220B, TYR256A, TYR256B, TYR421A, TYR421B, TYR435A, TYR435B, TYR437A, TYR437B, VAL160A, VAL160B, VAL179A, VAL179B, VAL183A, VAL183B, VAL223A, VAL223B, VAL240A, VAL240B, VAL243A, VAL243B, VAL258A, VAL258B, VAL261A, VAL261B, VAL356A, VAL356B, VAL388A, VAL388B, VAL399A, VAL399B, VAL426A, VAL426B
• A-C: ALA384C, ALA386A, ALA386C, ARG375A, ARG375C, ARG382A, ARG382C, ASN374A, ASN374C, ASP146A, ASP376A, ASP376C, GLN387C, GLY147A, GLY378A, GLY378C, GLY383C, ILE149A, ILE174A, LYS148A, LYS379A, LYS379C, LYS385C, PRO175A, PRO381A, PRO381C, THR173A, THR173C, THR377A, THR377C, TYR150A, TYR150C, TYR380A, TYR380C, TYR389C
• B-D: ALA384B, ALA384D, ARG166D, ARG169B, ARG169D, ARG382D, GLN168B, GLN168D, GLU144B, GLU144D, GLY170B, GLY170D, GLY383B, GLY383D, LEU167B, LEU167D, LEU172B, LEU172D, LYS165D, LYS171B, LYS171D, LYS385B, LYS385D, THR173B, THR173D
• C-D: ALA229C, ALA229D, ALA248C, ALA248D, ALA251C, ALA251D, ALA252C, ALA252D, ALA400C, ALA400D, ALA401C, ALA401D, ALA409C, ALA409D, ALA419C, ALA419D, ARG166C, ARG166D, ARG169C, ARG169D, ARG195C, ARG195D, ARG232C, ARG232D, ARG436C, ARG436D, ASN162C, ASN162D, ASN178C, ASN178D, ASN180C, ASN180D, ASN190C, ASN190D, ASN247C, ASN247D, ASN277C, ASN277D, ASN359C, ASN359D, ASN423C, ASN423D, ASP181C, ASP181D, ASP189C, ASP189D, ASP222C, ASP222D, ASP244C, ASP244D, ASP263C, ASP263D, ASP278C, ASP278D, ASP279C, ASP279D, ASP396C, ASP396D, ASP427C, ASP427D, ASP433C, ASP433D, CYS218C, CYS218D, CYS424C, CYS424D, GLN168C, GLN168D, GLN250C, GLN250D, GLN257C, GLN257D, GLN306C, GLN306D, GLN418C, GLN418D, GLU196C, GLU196D, GLU242C, GLU242D, GLU254C, GLU254D, GLU262C, GLU262D, GLU304C, GLU304D, GLU397C, GLU397D, GLU420C, GLU420D, GLY193C, GLY193D, GLY219C, GLY219D, GLY221C, GLY221D, GLY224C, GLY255C, GLY255D, GLY276C, GLY276D, GLY405C, GLY405D, GLY408C, GLY408D, GLY428C, GLY428D, HIS285C, HIS285D, HIS300C, HIS300D, HIS403C, HIS403D, HIS434C, HIS434D, ILE246C, ILE246D, ILE280C, ILE280D, ILE281C, ILE281D, ILE422C, ILE422D, LEU163C, LEU163D, LEU167C, LEU167D, LEU191C, LEU191D, LEU249C, LEU249D, LEU259C, LEU259D, LEU260C, LEU260D, LEU391C, LEU391D, LEU395C, LEU395D, LEU402C, LEU402D, LEU404C, LEU404D, LEU407C, LEU407D, LEU411C, LEU411D, LEU414C, LEU414D, LYS161C, LYS161D, LYS165C, LYS165D, LYS185C, LYS185D, LYS187C, LYS187D, LYS225C, LYS225D, LYS393C, LYS393D, LYS394C, LYS394D, LYS398C, LYS398D, LYS406C, LYS406D, LYS410C, LYS410D, LYS413C, LYS413D, LYS417C, LYS417D, LYS431C, LYS431D, MET253C, MET253D, MET357D, PHE188C, PHE188D, PHE301C, PHE301D, PHE355C, PHE355D, PHE390C, PHE390D, PHE430C, PHE430D, PRO245C, PRO245D, PRO353C, PRO353D, PRO392C, PRO392D, PRO429C, PRO429D, PRO432C, PRO432D, SER182C, SER182D, SER186C, SER186D, SER358C, SER358D, THR157C, THR157D, THR158C, THR158D, THR184C, THR184D, THR241C, THR241D, THR275C, THR275D, THR282C, THR282D, THR303C, THR303D, THR412C, THR412D, THR415C, THR415D, TYR164C, TYR164D, TYR192C, TYR192D, TYR220C, TYR220D, TYR256C, TYR256D, TYR421C, TYR421D, TYR435C, TYR435D, TYR437C, TYR437D, VAL160C, VAL160D, VAL179C, VAL179D, VAL183C, VAL183D, VAL223C, VAL223D, VAL240C, VAL240D, VAL243C, VAL243D, VAL258C, VAL258D, VAL261C, VAL261D, VAL264C, VAL264D, VAL356C, VAL356D, VAL388C, VAL388D, VAL399C, VAL399D, VAL426C, VAL426D