3H8D

crystal structure of myosin vi in complex with dab2 peptide

• Total interactions analyzed: 28
• Total true interactions: 20
• Strongest Interaction:
  • Chains: B-E
  • Int. Res.: 49
  • Norm. En. per Res.: -5.5303
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	7.2902	-38.456	-31.1658	38	0	1	1770	0	12	20
A-C	0.0	0.0	-6.0955	-6.0955	26	0	0	622	0	7	9
A-E	-71.698	-16.0189	-276.067	-363.7838	79	8	7	10216	1	20	12
A-F	-26.3628	-36.8577	-143.784	-207.0046	48	3	3	5287	5	25	22
A-H	0.0	0.0	-7.1805	-7.1805	5	0	0	265	0	2	1
B-C	0.0	37.6914	-73.913	-36.2216	47	2	0	3400	0	10	12
B-D	0.0	6.24	-3.2092	3.0308	15	0	0	377	0	5	4
B-E	-30.7061	-87.2623	-153.017	-270.9854	49	4	3	5621	5	25	24
B-F	-51.9364	2.7897	-245.511	-294.6577	79	10	7	9238	0	19	14
B-H	0.0	0.0	-2.427	-2.427	9	0	0	216	0	2	2
C-D	-17.7518	-49.3949	-48.5526	-115.6993	46	3	1	2630	4	20	24
C-E	0.0	0.0	-6.0515	-6.0515	16	1	0	421	0	2	1
C-G	-65.4823	-0.3005	-248.306	-314.0888	79	9	7	9349	0	17	14
C-H	-33.5631	-78.3627	-141.994	-253.9197	50	2	3	5443	4	26	24
D-E	0.0	0.0	-0.5261	-0.5261	3	0	0	76	0	1	0
D-G	-25.2535	-73.2774	-145.598	-244.1289	50	1	3	5436	5	25	22
D-H	-65.0336	-22.5618	-265.026	-352.6214	78	14	7	9707	2	19	12
E-F	0.0	-32.3699	-29.0053	-61.3752	18	1	0	1146	5	16	23
E-H	0.0	0.0	-29.9599	-29.9599	19	1	0	1096	0	6	10
G-H	0.0	-30.6939	-29.1046	-59.7985	18	3	0	1256	4	18	23

Interface residues

• A-B: ALA1222A, ALA1222B, ARG1146A, ARG1146B, ARG1149A, ARG1149B, ARG1152A, ARG1152B, ARG1218A, ARG1220A, ARG1220B, ARG1227A, ARG1227B, ARG1235B, GLN1147B, GLN1148B, GLN1228A, GLN1228B, GLU1223A, GLU1223B, GLU1231A, GLU1231B, GLY1221A, GLY1221B, ILE1224A, ILE1224B, ILE1232B, LEU1225A, LEU1225B, LYS1145A, PHE1150A, PHE1150B, PHE1151A, PHE1151B, PRO1226A, PRO1226B, THR1217A, THR1217B
• A-C: ALA1245C, ARG1146A, ARG1149A, ARG1218A, ARG1220A, ARG1235C, CYS1236C, GLN1147A, GLN1240C, GLN1243C, GLN1250C, GLU1212A, GLU1223A, GLU1247C, GLY1237C, LEU1196C, LEU1211A, LYS1201C, PHE1151A, PRO1180A, PRO1193C, PRO1194C, SER1244C, SER1248C, THR1217A, TYR1241C
• A-E: ALA1159A, ALA1175A, ALA1222A, ALA679E, ARG1152A, ARG1157A, ARG1218A, ARG1220A, ASN1210A, ASN685E, ASN686E, ASN703E, ASP1160A, ASP696E, ASP699E, CYS1207A, GLN1161A, GLN1185A, GLN1228A, GLN692E, GLU1187A, GLU1205A, GLU1208A, GLU1212A, GLU1213A, GLU1223A, GLU693E, GLY1171A, GLY1215A, GLY1221A, GLY675E, GLY689E, HIS1189A, HIS694E, ILE1153A, ILE1156A, ILE1182A, ILE1195A, ILE1224A, ILE690E, LEU1188A, LEU1197A, LEU1209A, LEU1211A, LEU1216A, LYS1168A, LYS1169A, LYS1170A, LYS1192A, LYS1219A, LYS687E, MET1186A, MET1204A, MET1206A, PHE1151A, PHE1155A, PHE1177A, PHE680E, PHE684E, PHE700E, PRO1154A, PRO1158A, PRO1165A, PRO691E, SER674E, SER677E, SER678E, SER681E, SER682E, THR1214A, THR1217A, THR676E, TRP1172A, TRP1173A, TYR1162A, TYR1174A, TYR683E, VAL688E, VAL695E
• A-F: ALA702F, ARG1152A, ARG1235A, ASN703F, ASN707F, ASN710F, ASP1191A, ASP696F, ASP698F, ASP699F, ASP701F, CYS1236A, GLN1228A, GLN704F, GLU1187A, GLU1231A, GLU1234A, GLU711F, GLY1171A, GLY1221A, GLY1237A, HIS1189A, HIS694F, HIS697F, ILE1153A, ILE1224A, ILE1232A, ILE709F, LEU1188A, LEU1196A, LEU1225A, LEU705F, LEU706F, LYS1169A, LYS1170A, LYS1192A, LYS708F, MET1186A, PHE1155A, PHE1229A, PHE700F, PRO1154A, PRO1190A, PRO1193A, PRO1194A, TRP1172A, TRP1233A, TYR1174A
• A-H: ARG1220A, ASN710H, GLU711H, ILE709H, LEU706H
• B-C: ARG1184B, ARG1227B, ARG1227C, ARG1235B, ARG1235C, ASN1262C, CYS1236B, CYS1236C, GLN1148B, GLN1228B, GLN1228C, GLN1240B, GLN1240C, GLN1243B, GLN1243C, GLU1230B, GLU1230C, GLU1231B, GLU1231C, GLU1234B, GLU1234C, GLU1247B, GLY1237B, GLY1237C, GLY1238B, GLY1238C, ILE1232C, ILE1239B, ILE1239C, ILE1246B, LEU1196C, LEU1225B, LEU1225C, LEU1242B, LEU1260C, LEU1263C, LEU1264C, LYS1145C, MET1259C, PRO1226B, PRO1226C, SER1244B, TRP1233B, TRP1233C, TYR1241B, TYR1241C, TYR1255C
• B-D: ALA1245B, ARG1149D, ARG1218D, ARG1220D, ARG1235B, GLN1240B, GLU1212D, GLU1223D, GLU1247B, GLY1237B, LYS1201B, SER1244B, SER1248B, THR1217D, TYR1241B
• B-E: ALA702E, ARG1152B, ARG1227B, ARG1235B, ASN703E, ASN707E, ASN710E, ASP1191B, ASP696E, ASP698E, ASP699E, ASP701E, CYS1236B, GLN1228B, GLN704E, GLU1187B, GLU1231B, GLU1234B, GLU711E, GLY1171B, GLY1221B, GLY1237B, HIS1189B, HIS694E, HIS697E, ILE1153B, ILE1224B, ILE1232B, ILE709E, LEU1188B, LEU1196B, LEU1225B, LEU705E, LEU706E, LYS1169B, LYS1170B, LYS1192B, LYS708E, MET1186B, PHE1155B, PHE1229B, PHE700E, PRO1154B, PRO1190B, PRO1193B, PRO1194B, TRP1172B, TRP1233B, TYR1174B
• B-F: ALA1159B, ALA1175B, ALA1222B, ALA679F, ARG1152B, ARG1157B, ARG1218B, ARG1220B, ASN1210B, ASN685F, ASN686F, ASN703F, ASP1160B, ASP696F, ASP699F, CYS1207B, GLN1161B, GLN1185B, GLN1228B, GLN692F, GLU1187B, GLU1205B, GLU1208B, GLU1212B, GLU1213B, GLU1223B, GLU693F, GLY1171B, GLY1215B, GLY1221B, GLY675F, GLY689F, HIS1189B, HIS694F, ILE1153B, ILE1156B, ILE1182B, ILE1195B, ILE1224B, ILE690F, LEU1188B, LEU1197B, LEU1209B, LEU1211B, LEU1216B, LYS1163B, LYS1168B, LYS1169B, LYS1170B, LYS1192B, LYS1219B, LYS687F, MET1186B, MET1204B, MET1206B, PHE1151B, PHE1155B, PHE1177B, PHE680F, PHE684F, PHE700F, PRO1154B, PRO1158B, PRO1165B, PRO691F, SER677F, SER678F, SER681F, SER682F, THR1214B, THR1217B, THR676F, TRP1172B, TRP1173B, TYR1162B, TYR1174B, TYR683F, VAL688F, VAL695F
• B-H: ARG1227B, ARG1235B, ASN703H, ASN707H, ASN710H, GLN704H, GLU1231B, GLU711H, LEU706H
• C-D: ALA1222C, ALA1222D, ARG1146C, ARG1146D, ARG1149C, ARG1149D, ARG1152C, ARG1152D, ARG1218D, ARG1220C, ARG1220D, ARG1227C, ARG1227D, ARG1235C, ASP1143C, ASP1178D, GLN1147D, GLN1148D, GLN1228C, GLN1228D, GLU1223C, GLU1223D, GLU1231C, GLU1231D, GLY1179D, GLY1221C, GLY1221D, HIS1176D, ILE1224C, ILE1224D, ILE1232C, LEU1225C, LEU1225D, LYS1145C, LYS1145D, MET1259D, PHE1150C, PHE1150D, PHE1151C, PHE1151D, PRO1226C, PRO1226D, THR1217C, THR1217D, TYR1255C, TYR1255D
• C-E: ARG1235C, ASN703E, ASN707E, ASN710E, CYS1236C, GLN704E, GLU1231C, GLU711E, GLY675E, ILE1195C, LEU1196C, LEU706E, LYS1192C, PRO1193C, PRO1194C, SER674E
• C-G: ALA1159C, ALA1175C, ALA1222C, ALA679G, ARG1152C, ARG1157C, ARG1218C, ARG1220C, ASN1210C, ASN685G, ASN703G, ASP1160C, ASP696G, ASP699G, CYS1207C, GLN1161C, GLN1185C, GLN1228C, GLN692G, GLU1187C, GLU1205C, GLU1208C, GLU1212C, GLU1213C, GLU1223C, GLU693G, GLY1171C, GLY1215C, GLY1221C, GLY675G, GLY689G, HIS1189C, HIS694G, ILE1153C, ILE1156C, ILE1182C, ILE1195C, ILE1224C, ILE690G, LEU1188C, LEU1197C, LEU1209C, LEU1211C, LEU1216C, LYS1168C, LYS1169C, LYS1170C, LYS1192C, LYS1219C, LYS687G, MET1186C, MET1204C, MET1206C, PHE1151C, PHE1155C, PHE1177C, PHE680G, PHE684G, PHE700G, PRO1154C, PRO1158C, PRO1165C, PRO1190C, PRO691G, SER674G, SER677G, SER678G, SER681G, SER682G, THR1214C, THR1217C, THR676G, TRP1172C, TRP1173C, TYR1162C, TYR1174C, TYR683G, VAL688G, VAL695G
• C-H: ALA702H, ARG1152C, ARG1227C, ARG1235C, ASN703H, ASN707H, ASN710H, ASP1191C, ASP696H, ASP698H, ASP699H, ASP701H, CYS1236C, GLN1228C, GLN704H, GLU1187C, GLU1231C, GLU1234C, GLU711H, GLY1171C, GLY1221C, GLY1237C, HIS1189C, HIS694H, HIS697H, ILE1153C, ILE1195C, ILE1224C, ILE1232C, ILE709H, LEU1188C, LEU1196C, LEU1225C, LEU705H, LEU706H, LYS1169C, LYS1170C, LYS1192C, LYS708H, MET1186C, PHE1155C, PHE1229C, PHE700H, PRO1154C, PRO1190C, PRO1193C, PRO1194C, TRP1172C, TRP1233C, TYR1174C
• D-E: ARG1220D, ASN710E, GLU711E
• D-G: ALA702G, ARG1152D, ARG1227D, ARG1235D, ASN703G, ASN707G, ASN710G, ASP1191D, ASP696G, ASP698G, ASP699G, ASP701G, CYS1236D, GLN1228D, GLN704G, GLU1187D, GLU1231D, GLU1234D, GLU711G, GLY1171D, GLY1221D, GLY1237D, HIS1189D, HIS694G, HIS697G, ILE1153D, ILE1195D, ILE1224D, ILE1232D, ILE709G, LEU1188D, LEU1196D, LEU1225D, LEU705G, LEU706G, LYS1169D, LYS1170D, LYS1192D, LYS708G, MET1186D, PHE1155D, PHE1229D, PHE700G, PRO1154D, PRO1190D, PRO1193D, PRO1194D, TRP1172D, TRP1233D, TYR1174D
• D-H: ALA1159D, ALA1175D, ALA1222D, ALA679H, ALA702H, ARG1152D, ARG1157D, ARG1218D, ARG1220D, ASN1210D, ASN685H, ASN686H, ASN703H, ASP1160D, ASP696H, ASP699H, CYS1207D, GLN1161D, GLN1185D, GLN1228D, GLN692H, GLU1187D, GLU1205D, GLU1208D, GLU1212D, GLU1213D, GLU1223D, GLU693H, GLY1171D, GLY1215D, GLY1221D, GLY675H, GLY689H, HIS1189D, HIS694H, ILE1153D, ILE1156D, ILE1182D, ILE1195D, ILE1224D, ILE690H, LEU1188D, LEU1197D, LEU1209D, LEU1211D, LEU1216D, LYS1168D, LYS1169D, LYS1170D, LYS1192D, LYS1219D, LYS687H, MET1186D, MET1204D, MET1206D, PHE1151D, PHE1155D, PHE1177D, PHE680H, PHE684H, PHE700H, PRO1154D, PRO1158D, PRO691H, SER677H, SER678H, SER681H, SER682H, THR1214D, THR1217D, THR676H, TRP1172D, TRP1173D, TYR1162D, TYR1174D, TYR683H, VAL688H, VAL695H
• E-F: ASP696E, ASP696F, ASP698E, ASP698F, ASP699E, ASP699F, GLN692E, GLN692F, GLU693E, GLU693F, HIS694E, HIS694F, HIS697E, HIS697F, PHE700E, PHE700F, VAL695E, VAL695F
• E-H: ASN703E, ASN703H, ASN707E, ASN707H, ASN710E, ASN710H, ASP699E, GLN704E, GLN704H, GLU711E, GLU711H, ILE709H, LEU706E, LEU706H, LYS708E, LYS708H, PHE700E, PHE700H, SER674E
• G-H: ASP696G, ASP696H, ASP698G, ASP698H, ASP699G, ASP699H, GLN692G, GLN692H, GLU693G, GLU693H, HIS694G, HIS694H, HIS697G, HIS697H, PHE700G, PHE700H, VAL695G, VAL695H