3GYX

crystal structure of adenylylsulfate reductase from desulfovibrio gigas

• Total interactions analyzed: 66
• Total true interactions: 29
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 346
  • Norm. En. per Res.: -5.7823
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-272.2438	-337.6974	-1390.72	-2000.6612	346	58	18	50730	26	126	99
A-C	0.0	0.0	-0.5067	-0.5067	15	0	0	89	0	11	15
A-D	-74.7681	-73.0981	-304.037	-451.9032	111	20	0	12703	6	30	16
A-E	0.0	0.0	-0.3692	-0.3692	12	0	0	100	0	8	9
A-G	-76.3079	-77.3774	-310.782	-464.4673	193	19	1	14087	11	72	73
A-H	-28.2116	-77.5364	-280.736	-386.484	94	11	3	10901	4	27	18
B-E	-41.0334	-74.8425	-293.73	-409.606	103	16	0	12529	7	29	17
B-G	-41.8486	-89.9093	-286.002	-417.7599	94	15	3	10860	7	27	18
C-D	-252.155	-305.3834	-1427.85	-1985.3885	355	56	16	50711	24	126	101
C-E	0.0	0.0	-0.0084	-0.0084	2	0	0	7	0	3	4
C-F	-8.9038	-51.4597	-287.9	-348.2635	110	16	0	12073	7	28	14
C-I	-48.938	-86.5592	-295.758	-431.2553	187	18	1	13812	10	70	74
C-J	-45.0277	-85.082	-293.448	-423.5578	93	12	3	10982	6	28	18
C-K	0.0	0.0	-0.0049	-0.0049	2	0	0	4	0	4	2
D-I	-30.1002	-81.773	-293.057	-404.9302	92	14	3	10971	5	25	17
E-F	-265.5205	-280.0997	-1406.7	-1952.3202	352	49	18	50403	21	127	98
E-G	0.0	0.0	-0.0103	-0.0103	3	0	0	8	0	2	2
E-K	-65.4291	-56.5812	-289.275	-411.2853	188	23	1	13678	9	70	71
E-L	-26.8846	-98.0257	-291.184	-416.0942	92	13	3	10865	6	29	17
F-K	-35.6849	-94.9069	-290.962	-421.5537	91	9	3	10897	5	27	17
G-H	-269.8255	-273.9106	-1391.32	-1935.056	348	51	17	50243	25	123	102
G-I	0.0	0.0	-0.6743	-0.6743	14	0	0	128	0	13	18
G-K	-6.3117	-16.4705	-12.0264	-34.8086	19	1	0	733	1	19	18
G-L	-45.3653	-48.1316	-321.874	-415.3709	108	16	0	12598	4	30	18
H-I	-45.8877	-66.884	-315.383	-428.1547	109	17	0	12674	5	28	16
I-J	-250.5925	-286.2942	-1434.07	-1970.9567	357	52	20	51636	26	133	103
I-K	0.0	10.739	-19.0538	-8.3148	27	1	0	1043	0	23	24
J-K	-39.9525	-74.7981	-303.785	-418.5356	107	19	0	12495	7	30	18
K-L	-267.7158	-329.4079	-1418.96	-2016.0837	353	53	19	50885	24	127	100

Interface residues

• A-B: ALA121B, ALA134B, ALA140A, ALA141B, ALA142A, ALA144A, ALA146B, ALA149B, ALA14A, ALA151B, ALA175A, ALA177A, ALA178A, ALA181A, ALA20B, ALA250A, ALA376A, ALA378A, ALA390A, ALA394A, ALA395A, ALA399A, ALA40A, ALA432A, ALA43A, ALA46B, ALA477A, ALA47A, ALA51A, ALA62A, ALA64B, ALA68B, ALA69A, ALA71A, ALA71B, ALA86A, ARG105B, ARG111A, ARG11A, ARG150A, ARG186A, ARG190A, ARG215A, ARG241A, ARG249A, ARG403A, ARG450A, ARG45A, ARG480A, ARG488A, ARG593A, ARG600A, ARG614A, ARG65B, ARG66A, ARG81B, ARG91A, ARG93B, ARG94A, ARG99B, ASN126B, ASN166A, ASN180A, ASN236A, ASN256A, ASN27B, ASN391A, ASN397A, ASN41B, ASN449A, ASN84A, ASN85A, ASN94B, ASP104A, ASP108A, ASP114A, ASP115A, ASP123B, ASP138A, ASP150B, ASP285A, ASP28B, ASP33B, ASP381A, ASP384A, ASP430A, ASP437A, ASP48A, ASP492A, ASP587A, ASP60A, ASP632A, ASP633A, ASP664A, ASP69B, ASP85B, ASP87A, ASP88A, CYS21B, CYS25B, CYS386A, CYS398A, CYS47B, CYS50B, CYS53B, CYS638A, CYS77B, GLN139B, GLN141A, GLN144B, GLN147B, GLN389A, GLN42B, GLN485A, GLN660A, GLN72A, GLU103A, GLU109B, GLU116B, GLU120B, GLU121A, GLU122A, GLU125B, GLU127B, GLU132B, GLU152B, GLU168A, GLU176A, GLU189A, GLU245A, GLU375A, GLU377A, GLU380A, GLU401A, GLU402A, GLU42A, GLU431A, GLU436A, GLU43B, GLU45B, GLU478A, GLU49B, GLU590A, GLU596A, GLU65A, GLU84B, GLY110A, GLY110B, GLY117B, GLY122B, GLY124A, GLY12A, GLY139A, GLY143B, GLY167A, GLY244A, GLY246A, GLY248A, GLY286A, GLY388A, GLY38A, GLY428A, GLY479A, GLY483A, GLY68A, GLY73A, GLY74B, GLY75B, GLY82B, GLY95B, HIS112A, HIS118A, HIS373A, HIS476A, HIS589A, ILE104B, ILE112B, ILE148B, ILE165A, ILE173A, ILE24B, ILE31B, ILE481A, ILE54B, ILE56B, ILE661A, ILE662A, ILE78B, ILE86B, ILE90B, LEU100A, LEU119A, LEU124B, LEU125A, LEU128B, LEU129B, LEU135B, LEU137A, LEU142B, LEU182A, LEU214A, LEU29B, LEU32B, LEU359A, LEU383A, LEU392A, LEU491A, LEU588A, LEU592A, LEU64A, LEU74A, LEU81A, LYS101B, LYS113B, LYS118B, LYS143A, LYS145B, LYS171A, LYS179A, LYS18B, LYS284A, LYS372A, LYS446A, LYS484A, LYS49A, LYS538A, LYS55B, LYS61A, LYS635A, LYS637A, LYS655A, LYS656A, LYS91B, LYS98B, MET22B, MET247A, MET30B, MET385A, MET486A, MET541A, MET542A, MET73B, MET87B, PHE100B, PHE102B, PHE115B, PHE120A, PHE130B, PHE192A, PHE212A, PHE363A, PHE382A, PHE40B, PHE41A, PHE639A, PHE70B, PHE92B, PRO103B, PRO108B, PRO10A, PRO114B, PRO119B, PRO126A, PRO138B, PRO253A, PRO26B, PRO2B, PRO34B, PRO400A, PRO429A, PRO435A, PRO44B, PRO537A, PRO657A, PRO663A, PRO66B, PRO72B, PRO79B, SER111B, SER116A, SER154B, SER169A, SER242A, SER52B, SER634A, SER63A, SER67A, SER83B, SER96B, THR106B, THR107B, THR131B, THR133B, THR136B, THR153B, THR19B, THR396A, THR3B, THR63B, THR76B, THR89B, THR9A, TRP123A, TRP128A, TRP251A, TRP255A, TRP293A, TRP379A, TRP393A, TRP433A, TRP46A, TRP489A, TRP48B, TRP636A, TRP88B, TYR107A, TYR170A, TYR23B, TYR252A, TYR287A, TYR438A, TYR448A, TYR490A, TYR50A, TYR51B, TYR658A, TYR659A, TYR67B, VAL113A, VAL127A, VAL137B, VAL13A, VAL140B, VAL172A, VAL174A, VAL235A, VAL243A, VAL254A, VAL387A, VAL434A, VAL447A, VAL44A, VAL482A, VAL487A, VAL70A, VAL90A
• A-C: ALA311A, ARG314A, ARG323C, ASP308A, ASP632C, GLU322A, GLU322C, GLY328A, GLY630C, HIS329A, LYS300A, LYS318A, LYS635C, PHE628C, SER634C
• A-D: ALA149D, ALA151D, ALA281A, ALA292A, ALA299A, ALA301A, ALA311A, ALA378A, ALA76A, ARG157A, ARG160A, ARG167D, ARG282A, ARG314A, ARG336A, ARG91A, ASN136A, ASN166D, ASN303A, ASN337A, ASN78A, ASN84A, ASP150D, ASP159D, ASP308A, ASP381A, ASP88A, ASP96A, CYS156D, CYS162D, CYS310A, CYS334A, GLN147D, GLN155D, GLN162A, GLU152D, GLU163D, GLU307A, GLU377A, GLU380A, GLY134A, GLY159A, GLY164D, GLY165D, GLY291A, GLY328A, GLY420A, HIS135A, HIS329A, HIS418A, HIS469A, ILE148D, ILE163A, ILE165A, ILE331A, ILE351A, ILE407A, ILE77A, LEU160D, LEU295A, LEU296A, LEU317A, LEU374A, LYS130A, LYS154A, LYS298A, LYS300A, LYS470A, MET164A, MET339A, MET340A, MET353A, MET385A, MET408A, MET92A, PHE158D, PHE278A, PHE294A, PHE297A, PHE471A, PHE622A, PRO155A, PRO161D, PRO280A, PRO289A, PRO332A, PRO409A, SER154D, SER158A, SER419A, SER75A, THR153D, THR302A, THR312A, THR333A, THR79A, THR95A, TRP128A, TRP157D, TRP161A, TRP251A, TRP293A, TYR309A, TYR352A, TYR80A, TYR89A, VAL156A, VAL279A, VAL290A, VAL330A, VAL93A
• A-E: ALA311E, ARG314E, ARG323A, ASP632A, ASP633A, GLU322A, GLY328E, HIS329E, LEU631A, LYS318E, LYS635A, SER634A
• A-G: ALA14A, ALA14G, ALA394A, ALA394G, ALA395A, ALA395G, ALA399G, ALA564A, ALA564G, ALA626A, ALA626G, ARG11A, ARG11G, ARG239A, ARG239G, ARG241A, ARG241G, ARG249A, ARG345A, ARG345G, ARG348A, ARG348G, ARG403A, ARG403G, ARG543A, ARG543G, ARG586A, ARG586G, ARG625A, ARG625G, ASN303A, ASN303G, ASN397A, ASN397G, ASN531A, ASN531G, ASN539A, ASN539G, ASN560A, ASN560G, ASP285A, ASP285G, ASP549A, ASP549G, ASP567A, ASP567G, ASP579A, ASP579G, ASP587A, ASP587G, ASP627A, ASP627G, CYS304A, CYS304G, CYS398A, CYS398G, CYS527A, CYS527G, CYS547A, CYS547G, GLU245A, GLU245G, GLU343A, GLU343G, GLU346A, GLU346G, GLU406A, GLU406G, GLU550A, GLU550G, GLU574A, GLU574G, GLU578A, GLU578G, GLU8A, GLU8G, GLY12A, GLY12G, GLY244A, GLY244G, GLY246A, GLY246G, GLY286A, GLY286G, GLY347A, GLY347G, GLY349A, GLY349G, GLY404A, GLY404G, GLY554A, GLY556A, GLY556G, GLY569A, GLY569G, ILE351A, ILE351G, ILE4A, ILE4G, ILE535A, ILE545A, ILE545G, LEU392A, LEU392G, LEU565A, LEU565G, LEU566A, LEU566G, LEU572A, LEU572G, LEU629A, LEU629G, LYS284A, LYS284G, LYS305A, LYS305G, LYS3A, LYS3G, LYS538A, LYS538G, LYS546A, LYS546G, LYS563A, LYS563G, LYS7A, LYS7G, MET247A, MET247G, MET344A, MET344G, MET408A, MET408G, MET542A, MET542G, MET575A, MET575G, PRO10A, PRO10G, PRO240A, PRO240G, PRO350A, PRO350G, PRO528A, PRO528G, PRO5A, PRO5G, SER242A, SER242G, SER405A, SER405G, SER536A, SER536G, SER562A, SER562G, SER6A, SER6G, THR396A, THR396G, THR526A, THR526G, THR557A, THR557G, THR561A, THR561G, THR568A, THR568G, THR9A, THR9G, TRP393A, TRP393G, TRP571A, TRP571G, TYR287A, TYR352A, TYR352G, TYR551A, TYR551G, TYR558A, TYR558G, TYR559A, TYR559G, TYR624A, TYR624G, VAL13A, VAL13G, VAL243A, VAL243G, VAL529A, VAL529G, VAL530A, VAL530G, VAL555A, VAL555G
• A-H: 3249CB4.0048, ALA39H, ALA524A, ALA584A, ALA61H, ALA64H, ALA68H, ALA71H, ARG239A, ARG543A, ARG65H, ARG93H, ASN41H, ASN517A, ASN531A, ASN539A, ASN94H, ASP33H, ASP579A, ASP69H, ASP6H, CYS10H, CYS47H, CYS527A, CYS547A, GLN42H, GLU35H, GLU36H, GLU43H, GLU45H, GLU533A, GLU550A, GLU574A, GLU577A, GLU578A, GLU8A, GLY523A, GLY74H, GLY75H, ILE31H, ILE4A, ILE535A, ILE545A, LEU32H, LEU544A, LEU572A, LEU576A, LEU581A, LEU583A, LYS38H, LYS3A, LYS3A5, LYS522A, LYS538A, LYS546A, LYS582A, LYS7A, LYS9H, MET22H, MET30H, MET37H, MET541A, MET542A, MET575A, MET73H, PHE40H, PHE540A, PHE70H, PRO2H, PRO34H, PRO44H, PRO528A, PRO532A, PRO5A, PRO66H, PRO72H, PRO7H, SER525A, SER536A, SER580A, SER6A, SER8H, THR3H, THR526A, THR63H, THR76H, TRP571A, TYR4H, TYR534A, TYR551A, TYR67H, VAL529A, VAL530A, VAL5H
• B-E: ALA149B, ALA151B, ALA281E, ALA292E, ALA299E, ALA301E, ALA311E, ALA378E, ALA76E, ARG157E, ARG160E, ARG167B, ARG282E, ARG314E, ARG336E, ASN136E, ASN166B, ASN303E, ASN337E, ASN78E, ASN84E, ASP150B, ASP159B, ASP308E, ASP381E, ASP96E, CYS156B, CYS162B, CYS310E, GLN155B, GLN162E, GLU152B, GLU163B, GLU307E, GLU377E, GLY134E, GLY159E, GLY164B, GLY165B, GLY291E, GLY328E, HIS135E, HIS329E, HIS418E, HIS469E, ILE148B, ILE163E, ILE165E, ILE331E, ILE351E, ILE407E, ILE77E, LEU160B, LEU295E, LEU296E, LEU317E, LEU374E, LYS130E, LYS154E, LYS298E, LYS300E, LYS470E, MET164E, MET339E, MET340E, MET353E, MET385E, MET408E, MET92E, PHE158B, PHE278E, PHE283E, PHE294E, PHE471E, PHE622E, PRO155E, PRO161B, PRO280E, PRO289E, PRO332E, PRO409E, SER154B, SER158E, SER419E, SER75E, THR153B, THR302E, THR333E, THR79E, THR95E, TRP128E, TRP157B, TRP161E, TRP251E, TRP293E, TYR309E, TYR352E, TYR80E, TYR89E, VAL156E, VAL290E, VAL330E, VAL93E
• B-G: ALA39B, ALA524G, ALA584G, ALA61B, ALA64B, ALA68B, ALA71B, ARG239G, ARG543G, ARG65B, ARG93B, ASN41B, ASN517G, ASN531G, ASN539G, ASN94B, ASP33B, ASP579G, ASP69B, ASP6B, CYS10B, CYS47B, CYS527G, CYS547G, GLN42B, GLU35B, GLU36B, GLU43B, GLU45B, GLU533G, GLU550G, GLU574G, GLU577G, GLU578G, GLU8G, GLY523G, GLY74B, GLY75B, ILE31B, ILE4G, ILE535G, ILE545G, ILE62B, LEU32B, LEU544G, LEU572G, LEU576G, LEU581G, LEU583G, LYS38B, LYS3G, LYS522G, LYS538G, LYS546G, LYS582G, LYS7G, LYS9B, MET22B, MET30B, MET37B, MET541G, MET542G, MET573G, MET575G, MET73B, PHE40B, PHE540G, PHE70B, PRO2B, PRO34B, PRO44B, PRO528G, PRO532G, PRO5G, PRO66B, PRO72B, PRO7B, SER525G, SER536G, SER580G, SER6G, SER8B, THR3B, THR526G, THR63B, THR76B, TRP571G, TYR4B, TYR534G, TYR551G, TYR67B, VAL529G, VAL530G, VAL5B
• C-D: ALA121D, ALA134D, ALA140C, ALA141D, ALA142C, ALA144C, ALA146D, ALA149D, ALA14C, ALA151D, ALA175C, ALA177C, ALA178C, ALA181C, ALA20D, ALA250C, ALA376C, ALA378C, ALA390C, ALA394C, ALA395C, ALA399C, ALA40C, ALA432C, ALA43C, ALA46D, ALA477C, ALA47C, ALA51C, ALA62C, ALA64D, ALA68D, ALA69C, ALA71C, ALA71D, ALA86C, ARG105D, ARG111C, ARG11C, ARG150C, ARG186C, ARG190C, ARG215C, ARG241C, ARG249C, ARG450C, ARG45C, ARG480C, ARG488C, ARG593C, ARG600C, ARG65D, ARG66C, ARG81D, ARG91C, ARG93D, ARG94C, ARG99D, ASN126D, ASN166C, ASN180C, ASN236C, ASN256C, ASN27D, ASN391C, ASN397C, ASN41D, ASN444C, ASN449C, ASN597C, ASN84C, ASN85C, ASN94D, ASP104C, ASP108C, ASP114C, ASP115C, ASP123D, ASP138C, ASP150D, ASP285C, ASP28D, ASP33D, ASP381C, ASP384C, ASP430C, ASP437C, ASP48C, ASP492C, ASP587C, ASP60C, ASP632C, ASP633C, ASP664C, ASP69D, ASP85D, ASP87C, ASP88C, CYS21D, CYS25D, CYS386C, CYS398C, CYS47D, CYS50D, CYS53D, CYS638C, CYS77D, GLN139D, GLN141C, GLN144D, GLN147D, GLN184C, GLN371C, GLN389C, GLN42D, GLN485C, GLN660C, GLN72C, GLU103C, GLU109D, GLU116D, GLU120D, GLU121C, GLU122C, GLU125D, GLU127D, GLU132D, GLU152D, GLU168C, GLU176C, GLU17D, GLU189C, GLU245C, GLU375C, GLU377C, GLU380C, GLU401C, GLU402C, GLU42C, GLU431C, GLU436C, GLU43D, GLU45D, GLU478C, GLU49D, GLU590C, GLU596C, GLU65C, GLU84D, GLY110C, GLY110D, GLY117D, GLY122D, GLY124C, GLY12C, GLY139C, GLY143D, GLY167C, GLY183C, GLY244C, GLY246C, GLY248C, GLY286C, GLY388C, GLY38C, GLY428C, GLY479C, GLY483C, GLY68C, GLY73C, GLY74D, GLY75D, GLY82D, GLY95D, HIS112C, HIS118C, HIS373C, HIS476C, HIS589C, ILE104D, ILE112D, ILE148D, ILE165C, ILE173C, ILE24D, ILE31D, ILE481C, ILE54D, ILE56D, ILE661C, ILE662C, ILE78D, ILE86D, ILE90D, LEU100C, LEU109C, LEU119C, LEU124D, LEU125C, LEU128D, LEU129D, LEU135D, LEU137C, LEU142D, LEU182C, LEU214C, LEU29D, LEU32D, LEU359C, LEU374C, LEU383C, LEU392C, LEU491C, LEU588C, LEU592C, LEU64C, LEU74C, LEU81C, LYS101D, LYS113D, LYS118D, LYS143C, LYS145D, LYS171C, LYS179C, LYS18D, LYS284C, LYS372C, LYS446C, LYS484C, LYS49C, LYS538C, LYS55D, LYS61C, LYS635C, LYS637C, LYS655C, LYS656C, LYS91D, LYS98D, MET22D, MET247C, MET30D, MET385C, MET486C, MET541C, MET542C, MET73D, MET87D, PHE100D, PHE102D, PHE115D, PHE120C, PHE130D, PHE192C, PHE212C, PHE363C, PHE382C, PHE40D, PHE41C, PHE613C, PHE639C, PHE70D, PHE92D, PRO103D, PRO108D, PRO10C, PRO114D, PRO119D, PRO126C, PRO138D, PRO240C, PRO253C, PRO26D, PRO2D, PRO34D, PRO400C, PRO429C, PRO435C, PRO44D, PRO537C, PRO657C, PRO663C, PRO66D, PRO72D, PRO79D, SER111D, SER116C, SER154D, SER169C, SER242C, SER52D, SER634C, SER63C, SER67C, SER83D, SER96D, THR106D, THR107D, THR131D, THR133D, THR136D, THR153D, THR19D, THR396C, THR3D, THR63D, THR76D, THR89D, THR9C, TRP123C, TRP128C, TRP251C, TRP255C, TRP293C, TRP379C, TRP393C, TRP433C, TRP46C, TRP489C, TRP48D, TRP636C, TRP88D, TYR107C, TYR170C, TYR23D, TYR252C, TYR287C, TYR413C, TYR438C, TYR448C, TYR490C, TYR50C, TYR51D, TYR658C, TYR659C, TYR67D, VAL113C, VAL127C, VAL137D, VAL13C, VAL140D, VAL172C, VAL174C, VAL235C, VAL243C, VAL254C, VAL387C, VAL434C, VAL447C, VAL44C, VAL482C, VAL487C, VAL70C, VAL90C
• C-E: HIS329C, LYS635E
• C-F: ALA149F, ALA151F, ALA281C, ALA292C, ALA299C, ALA301C, ALA311C, ALA378C, ALA76C, ARG157C, ARG160C, ARG167F, ARG282C, ARG314C, ARG336C, ARG91C, ASN136C, ASN166F, ASN337C, ASN78C, ASN84C, ASP131C, ASP150F, ASP153C, ASP159F, ASP308C, ASP381C, ASP88C, ASP96C, CYS156F, CYS162F, CYS310C, GLN155F, GLN162C, GLU152F, GLU163F, GLU307C, GLU377C, GLU380C, GLY134C, GLY159C, GLY164F, GLY165F, GLY291C, GLY328C, HIS135C, HIS329C, HIS373C, HIS418C, HIS469C, ILE129C, ILE163C, ILE165C, ILE331C, ILE351C, ILE407C, ILE77C, LEU160F, LEU295C, LEU296C, LEU317C, LEU374C, LYS130C, LYS154C, LYS298C, LYS300C, LYS327C, LYS470C, MET164C, MET339C, MET340C, MET353C, MET385C, MET408C, MET92C, PHE158F, PHE278C, PHE283C, PHE294C, PHE471C, PHE622C, PRO155C, PRO161F, PRO280C, PRO289C, PRO332C, PRO409C, SER154F, SER158C, SER419C, SER75C, THR153F, THR302C, THR333C, THR79C, THR95C, TRP128C, TRP157F, TRP161C, TRP251C, TRP293C, TYR309C, TYR352C, TYR80C, TYR89C, VAL156C, VAL279C, VAL290C, VAL330C, VAL93C
• C-I: ALA14C, ALA14I, ALA394C, ALA395C, ALA395I, ALA564C, ALA564I, ALA626C, ALA626I, ARG11C, ARG11I, ARG239C, ARG239I, ARG241C, ARG241I, ARG342C, ARG345C, ARG345I, ARG348C, ARG348I, ARG403C, ARG403I, ARG543C, ARG543I, ARG586C, ARG586I, ARG625C, ARG625I, ASN303C, ASN303I, ASN397C, ASN397I, ASN531C, ASN531I, ASN539C, ASN539I, ASN560C, ASN560I, ASP285C, ASP285I, ASP549C, ASP549I, ASP567C, ASP567I, ASP579C, ASP579I, ASP587C, ASP587I, ASP627C, ASP627I, CYS304C, CYS304I, CYS398C, CYS398I, CYS527C, CYS527I, CYS547C, CYS547I, GLU245C, GLU245I, GLU343C, GLU343I, GLU346C, GLU346I, GLU406C, GLU406I, GLU550C, GLU550I, GLU574C, GLU578C, GLU578I, GLU8C, GLU8I, GLY12C, GLY12I, GLY244C, GLY244I, GLY246C, GLY246I, GLY347C, GLY347I, GLY349C, GLY349I, GLY404C, GLY404I, GLY556C, GLY556I, GLY569C, GLY569I, ILE351C, ILE351I, ILE4C, ILE4I, ILE535C, ILE535I, ILE545C, ILE545I, LEU392C, LEU392I, LEU565C, LEU565I, LEU566C, LEU566I, LEU572C, LEU572I, LEU629C, LEU629I, LYS284C, LYS284I, LYS305C, LYS305I, LYS3C, LYS3I, LYS538C, LYS538I, LYS546C, LYS546I, LYS563C, LYS563I, LYS7I, MET247C, MET247I, MET344C, MET344I, MET408C, MET408I, MET542C, MET542I, MET575C, MET575I, PRO10C, PRO10I, PRO240C, PRO240I, PRO350C, PRO350I, PRO528C, PRO528I, PRO5C, PRO5I, SER242C, SER242I, SER405C, SER405I, SER536C, SER536I, SER562C, SER562I, SER6C, SER6I, THR396C, THR396I, THR526I, THR557C, THR557I, THR561C, THR561I, THR568C, THR568I, THR9C, THR9I, TRP393C, TRP393I, TRP571C, TRP571I, TYR287C, TYR287I, TYR352C, TYR352I, TYR551C, TYR551I, TYR558C, TYR558I, TYR559C, TYR559I, TYR624C, TYR624I, VAL13C, VAL13I, VAL243C, VAL243I, VAL529C, VAL529I, VAL530C, VAL530I, VAL555C, VAL555I
• C-J: ALA39J, ALA524C, ALA584C, ALA61J, ALA64J, ALA68J, ALA71J, ARG239C, ARG543C, ARG65J, ARG93J, ASN41J, ASN517C, ASN531C, ASN539C, ASP33J, ASP579C, ASP69J, ASP6J, CYS10J, CYS47J, CYS527C, CYS547C, GLN42J, GLU35J, GLU36J, GLU43J, GLU45J, GLU49J, GLU533C, GLU550C, GLU574C, GLU577C, GLU578C, GLU8C, GLY523C, GLY74J, GLY75J, ILE31J, ILE4C, ILE535C, ILE545C, LEU32J, LEU544C, LEU572C, LEU576C, LEU581C, LEU583C, LYS38J, LYS3C, LYS522C, LYS538C, LYS546C, LYS582C, LYS7C, LYS9J, MET22J, MET30J, MET37J, MET541C, MET542C, MET573C, MET575C, MET73J, PHE40J, PHE540C, PHE70J, PRO2J, PRO34J, PRO44J, PRO528C, PRO532C, PRO5C, PRO66J, PRO72J, PRO7J, SER525C, SER536C, SER580C, SER6C, SER8J, THR3J, THR526C, THR63J, THR76J, TRP571C, TYR4J, TYR534C, TYR551C, TYR67J, VAL529C, VAL530C, VAL5J
• C-K: GLU307K, LYS305C
• D-I: ALA39D, ALA524I, ALA584I, ALA61D, ALA64D, ALA68D, ALA71D, ARG239I, ARG543I, ARG65D, ARG93D, ASN41D, ASN517I, ASN531I, ASN539I, ASN94D, ASP33D, ASP579I, ASP69D, ASP6D, CYS10D, CYS47D, CYS527I, CYS547I, GLN42D, GLU35D, GLU36D, GLU43D, GLU45D, GLU533I, GLU550I, GLU574I, GLU577I, GLU578I, GLU8I, GLY523I, GLY74D, GLY75D, ILE31D, ILE4I, ILE535I, ILE545I, LEU32D, LEU544I, LEU572I, LEU576I, LEU581I, LEU583I, LYS38D, LYS3I, LYS522I, LYS538I, LYS546I, LYS582I, LYS7I, LYS9D, MET22D, MET30D, MET37D, MET541I, MET542I, MET575I, MET73D, PHE40D, PHE540I, PHE70D, PRO2D, PRO34D, PRO44D, PRO528I, PRO532I, PRO5I, PRO66D, PRO72D, PRO7D, SER525I, SER536I, SER580I, SER6I, SER8D, THR3D, THR526I, THR63D, THR76D, TRP571I, TYR4D, TYR534I, TYR551I, TYR67D, VAL529I, VAL530I, VAL5D
• E-F: ALA121F, ALA134F, ALA140E, ALA141F, ALA142E, ALA144E, ALA146F, ALA149F, ALA14E, ALA151F, ALA175E, ALA177E, ALA178E, ALA181E, ALA20F, ALA250E, ALA376E, ALA378E, ALA390E, ALA394E, ALA395E, ALA399E, ALA40E, ALA432E, ALA43E, ALA46F, ALA477E, ALA47E, ALA51E, ALA62E, ALA64F, ALA68F, ALA69E, ALA71E, ALA71F, ALA86E, ARG105F, ARG111E, ARG11E, ARG150E, ARG186E, ARG190E, ARG215E, ARG241E, ARG249E, ARG403E, ARG450E, ARG45E, ARG480E, ARG488E, ARG593E, ARG600E, ARG614E, ARG65F, ARG66E, ARG81F, ARG91E, ARG93F, ARG94E, ARG99F, ASN126F, ASN166E, ASN180E, ASN236E, ASN256E, ASN27F, ASN391E, ASN397E, ASN41F, ASN444E, ASN449E, ASN85E, ASN94F, ASP104E, ASP108E, ASP114E, ASP115E, ASP123F, ASP138E, ASP150F, ASP285E, ASP28F, ASP33F, ASP381E, ASP384E, ASP430E, ASP437E, ASP48E, ASP492E, ASP587E, ASP60E, ASP632E, ASP633E, ASP664E, ASP69F, ASP85F, ASP87E, ASP88E, CYS21F, CYS25F, CYS386E, CYS398E, CYS47F, CYS50F, CYS53F, CYS638E, CYS77F, GLN139F, GLN141E, GLN144F, GLN147F, GLN371E, GLN389E, GLN42F, GLN485E, GLN660E, GLN72E, GLU103E, GLU109F, GLU116F, GLU120F, GLU121E, GLU122E, GLU125F, GLU127F, GLU132F, GLU152F, GLU168E, GLU176E, GLU189E, GLU245E, GLU375E, GLU377E, GLU380E, GLU401E, GLU402E, GLU42E, GLU431E, GLU43F, GLU45F, GLU478E, GLU49F, GLU590E, GLU596E, GLU615E, GLU65E, GLU84F, GLY110E, GLY110F, GLY117F, GLY122F, GLY124E, GLY12E, GLY139E, GLY143F, GLY167E, GLY183E, GLY244E, GLY246E, GLY248E, GLY286E, GLY388E, GLY38E, GLY428E, GLY479E, GLY483E, GLY68E, GLY73E, GLY74F, GLY75F, GLY82F, GLY95F, HIS112E, HIS118E, HIS373E, HIS476E, HIS589E, ILE104F, ILE112F, ILE148F, ILE165E, ILE173E, ILE24F, ILE31F, ILE481E, ILE54F, ILE56F, ILE661E, ILE662E, ILE78F, ILE86F, ILE90F, LEU100E, LEU119E, LEU124F, LEU125E, LEU128F, LEU129F, LEU135F, LEU137E, LEU142F, LEU182E, LEU214E, LEU29F, LEU32F, LEU359E, LEU374E, LEU383E, LEU392E, LEU491E, LEU588E, LEU592E, LEU64E, LEU74E, LEU81E, LYS101F, LYS113F, LYS118F, LYS143E, LYS145F, LYS171E, LYS179E, LYS18F, LYS284E, LYS372E, LYS446E, LYS484E, LYS49E, LYS538E, LYS55F, LYS61E, LYS635E, LYS637E, LYS655E, LYS656E, LYS91F, LYS98F, MET22F, MET247E, MET30F, MET385E, MET486E, MET541E, MET542E, MET73F, MET87F, PHE100F, PHE102F, PHE115F, PHE120E, PHE130F, PHE192E, PHE212E, PHE363E, PHE382E, PHE40F, PHE41E, PHE639E, PHE654E, PHE70F, PHE92F, PRO103F, PRO108F, PRO10E, PRO114F, PRO119F, PRO126E, PRO138F, PRO240E, PRO253E, PRO26F, PRO2F, PRO34F, PRO400E, PRO429E, PRO435E, PRO44F, PRO537E, PRO657E, PRO663E, PRO66F, PRO72F, PRO79F, SER111F, SER116E, SER169E, SER242E, SER52F, SER634E, SER63E, SER67E, SER83F, SER96F, THR106F, THR107F, THR131F, THR133F, THR136F, THR153F, THR19F, THR396E, THR3F, THR63F, THR76F, THR89F, THR9E, TRP123E, TRP128E, TRP251E, TRP255E, TRP293E, TRP379E, TRP393E, TRP433E, TRP46E, TRP489E, TRP48F, TRP636E, TRP88F, TYR107E, TYR170E, TYR23F, TYR252E, TYR287E, TYR413E, TYR438E, TYR448E, TYR490E, TYR50E, TYR51F, TYR658E, TYR659E, TYR67F, VAL113E, VAL127E, VAL137F, VAL13E, VAL140F, VAL172E, VAL174E, VAL235E, VAL243E, VAL254E, VAL387E, VAL434E, VAL447E, VAL44E, VAL482E, VAL487E, VAL70E, VAL90E, VAL97F
• E-G: GLU307G, LYS305E, LYS305G
• E-K: ALA14E, ALA14K, ALA394E, ALA394K, ALA395E, ALA395K, ALA564E, ALA564K, ALA626E, ALA626K, ARG11E, ARG11K, ARG239E, ARG239K, ARG241E, ARG241K, ARG345E, ARG345K, ARG348E, ARG348K, ARG403E, ARG403K, ARG543E, ARG543K, ARG586E, ARG586K, ARG625E, ARG625K, ASN303E, ASN303K, ASN397E, ASN397K, ASN531E, ASN531K, ASN539E, ASN539K, ASN560E, ASN560K, ASP285E, ASP285K, ASP549E, ASP549K, ASP567E, ASP567K, ASP579E, ASP579K, ASP587E, ASP587K, ASP627E, ASP627K, CYS304E, CYS304K, CYS398E, CYS398K, CYS527E, CYS527K, CYS547E, CYS547K, GLU245E, GLU245K, GLU343E, GLU343K, GLU346E, GLU346K, GLU406E, GLU406K, GLU550E, GLU550K, GLU578E, GLU578K, GLU8E, GLU8K, GLY12E, GLY12K, GLY244E, GLY244K, GLY246E, GLY246K, GLY286E, GLY286K, GLY347E, GLY347K, GLY349E, GLY349K, GLY404E, GLY404K, GLY556E, GLY556K, GLY569E, GLY569K, ILE351E, ILE351K, ILE4E, ILE4K, ILE545E, ILE545K, LEU392E, LEU392K, LEU565E, LEU565K, LEU566E, LEU566K, LEU572E, LEU572K, LEU588K, LEU629E, LEU629K, LYS284E, LYS284K, LYS305E, LYS305K, LYS3E, LYS3K, LYS538E, LYS538K, LYS546E, LYS546K, LYS563E, LYS563K, LYS7E, MET247E, MET247K, MET344E, MET344K, MET408E, MET408K, MET542E, MET542K, MET575E, MET575K, PRO10E, PRO10K, PRO240E, PRO240K, PRO350E, PRO350K, PRO528E, PRO528K, PRO5E, PRO5K, SER242E, SER242K, SER405E, SER405K, SER536E, SER536K, SER562E, SER562K, SER6E, SER6K, THR396E, THR396K, THR526E, THR526K, THR557E, THR557K, THR561E, THR561K, THR568E, THR568K, THR9E, THR9K, TRP393E, TRP393K, TRP571E, TRP571K, TYR287E, TYR287K, TYR352E, TYR352K, TYR551E, TYR551K, TYR558E, TYR558K, TYR559E, TYR559K, TYR624E, TYR624K, VAL13E, VAL13K, VAL243E, VAL243K, VAL529E, VAL529K, VAL530E, VAL530K, VAL555E, VAL555K
• E-L: ALA39L, ALA524E, ALA584E, ALA61L, ALA64L, ALA68L, ALA71L, ARG239E, ARG543E, ARG65L, ARG93L, ASN41L, ASN517E, ASN531E, ASN539E, ASN94L, ASP33L, ASP579E, ASP69L, ASP6L, CYS10L, CYS47L, CYS527E, CYS547E, GLN42L, GLU35L, GLU36L, GLU43L, GLU45L, GLU533E, GLU550E, GLU574E, GLU577E, GLU578E, GLY523E, GLY74L, GLY75L, ILE31L, ILE4E, ILE535E, ILE545E, ILE62L, LEU32L, LEU544E, LEU572E, LEU576E, LEU581E, LEU583E, LYS38L, LYS3E, LYS522E, LYS538E, LYS546E, LYS582E, LYS7E, LYS9L, MET22L, MET30L, MET37L, MET541E, MET542E, MET573E, MET575E, MET73L, PHE40L, PHE540E, PHE70L, PRO2L, PRO34L, PRO44L, PRO528E, PRO532E, PRO5E, PRO66L, PRO72L, PRO7L, SER525E, SER536E, SER580E, SER6E, SER8L, THR3L, THR526E, THR63L, THR76L, TRP571E, TYR4L, TYR534E, TYR67L, VAL529E, VAL530E, VAL5L
• F-K: ALA39F, ALA524K, ALA584K, ALA61F, ALA64F, ALA68F, ALA71F, ARG239K, ARG543K, ARG65F, ARG93F, ASN41F, ASN517K, ASN531K, ASN539K, ASN94F, ASP33F, ASP579K, ASP69F, ASP6F, CYS10F, CYS47F, CYS527K, CYS547K, GLN42F, GLU35F, GLU36F, GLU43F, GLU45F, GLU533K, GLU550K, GLU574K, GLU577K, GLU578K, GLU8K, GLY523K, GLY74F, GLY75F, ILE31F, ILE4K, ILE535K, ILE545K, LEU32F, LEU544K, LEU572K, LEU576K, LEU581K, LEU583K, LYS38F, LYS3K, LYS522K, LYS538K, LYS546K, LYS582K, LYS7K, LYS9F, MET22F, MET30F, MET37F, MET541K, MET542K, MET575K, MET73F, PHE40F, PHE540K, PHE70F, PRO2F, PRO34F, PRO44F, PRO528K, PRO532K, PRO5K, PRO66F, PRO72F, PRO7F, SER525K, SER536K, SER580K, SER6K, SER8F, THR3F, THR526K, THR63F, THR76F, TRP571K, TYR4F, TYR534K, TYR67F, VAL529K, VAL530K, VAL5F
• G-H: ALA121H, ALA134H, ALA140G, ALA141H, ALA142G, ALA144G, ALA146H, ALA149H, ALA14G, ALA151H, ALA175G, ALA177G, ALA178G, ALA181G, ALA20H, ALA250G, ALA376G, ALA378G, ALA390G, ALA394G, ALA395G, ALA399G, ALA40G, ALA432G, ALA43G, ALA46H, ALA477G, ALA47G, ALA51G, ALA62G, ALA64H, ALA68H, ALA69G, ALA71G, ALA71H, ALA86G, ARG105H, ARG111G, ARG11G, ARG150G, ARG186G, ARG190G, ARG215G, ARG241G, ARG249G, ARG403G, ARG450G, ARG45G, ARG480G, ARG488G, ARG593G, ARG600G, ARG618G, ARG65H, ARG66G, ARG81H, ARG91G, ARG93H, ARG94G, ARG99H, ASN126H, ASN166G, ASN180G, ASN236G, ASN256G, ASN27H, ASN391G, ASN397G, ASN41H, ASN449G, ASN85G, ASN94H, ASP104G, ASP108G, ASP114G, ASP115G, ASP123H, ASP138G, ASP150H, ASP285G, ASP28H, ASP33H, ASP381G, ASP384G, ASP430G, ASP437G, ASP48G, ASP492G, ASP587G, ASP60G, ASP632G, ASP633G, ASP664G, ASP69H, ASP85H, ASP87G, ASP88G, CYS21H, CYS25H, CYS386G, CYS398G, CYS47H, CYS50H, CYS53H, CYS638G, CYS77H, GLN139H, GLN141G, GLN144H, GLN147H, GLN389G, GLN42H, GLN485G, GLN660G, GLN72G, GLU103G, GLU109H, GLU116H, GLU120H, GLU121G, GLU122G, GLU125H, GLU127H, GLU132H, GLU152H, GLU168G, GLU176G, GLU189G, GLU245G, GLU375G, GLU377G, GLU380G, GLU401G, GLU402G, GLU42G, GLU431G, GLU43H, GLU45H, GLU478G, GLU49H, GLU590G, GLU596G, GLU615G, GLU65G, GLU84H, GLY110G, GLY110H, GLY117H, GLY122H, GLY124G, GLY12G, GLY139G, GLY143H, GLY167G, GLY183G, GLY244G, GLY246G, GLY248G, GLY286G, GLY388G, GLY38G, GLY428G, GLY479G, GLY483G, GLY68G, GLY73G, GLY74H, GLY75H, GLY82H, GLY95H, HIS112G, HIS118G, HIS373G, HIS476G, HIS589G, ILE104H, ILE112H, ILE148H, ILE165G, ILE173G, ILE24H, ILE31H, ILE481G, ILE54H, ILE56H, ILE661G, ILE662G, ILE78H, ILE86H, ILE90H, LEU100G, LEU119G, LEU124H, LEU125G, LEU128H, LEU129H, LEU135H, LEU142H, LEU182G, LEU214G, LEU29H, LEU32H, LEU359G, LEU374G, LEU383G, LEU392G, LEU491G, LEU588G, LEU592G, LEU64G, LEU74G, LEU81G, LYS101H, LYS113H, LYS118H, LYS143G, LYS145H, LYS171G, LYS179G, LYS18H, LYS284G, LYS372G, LYS446G, LYS484G, LYS49G, LYS538G, LYS55H, LYS61G, LYS635G, LYS637G, LYS655G, LYS656G, LYS91H, LYS98H, MET22H, MET247G, MET30H, MET385G, MET541G, MET542G, MET73H, MET87H, PHE100H, PHE102H, PHE115H, PHE120G, PHE130H, PHE192G, PHE212G, PHE363G, PHE382G, PHE40H, PHE41G, PHE613G, PHE639G, PHE70H, PHE92H, PRO103H, PRO108H, PRO10G, PRO114H, PRO119H, PRO126G, PRO138H, PRO240G, PRO253G, PRO26H, PRO2H, PRO34H, PRO400G, PRO429G, PRO435G, PRO44H, PRO537G, PRO657G, PRO663G, PRO66H, PRO72H, PRO79H, SER111H, SER116G, SER154H, SER169G, SER242G, SER52H, SER634G, SER63G, SER67G, SER83H, SER96H, THR106H, THR107H, THR131H, THR133H, THR136H, THR153H, THR19H, THR396G, THR3H, THR63H, THR76H, THR89H, THR9G, TRP123G, TRP128G, TRP251G, TRP255G, TRP293G, TRP379G, TRP393G, TRP433G, TRP46G, TRP489G, TRP48H, TRP636G, TRP88H, TYR107G, TYR170G, TYR23H, TYR252G, TYR287G, TYR438G, TYR448G, TYR490G, TYR50G, TYR51H, TYR658G, TYR659G, TYR67H, VAL113G, VAL127G, VAL137H, VAL13G, VAL140H, VAL172G, VAL174G, VAL235G, VAL243G, VAL254G, VAL387G, VAL434G, VAL447G, VAL44G, VAL482G, VAL487G, VAL70G, VAL90G, VAL97H
• G-I: ALA311I, ARG314I, ARG323G, ASP632G, GLU322G, GLY328I, GLY630G, HIS329I, LYS300I, LYS318G, LYS318I, LYS635G, PRO319G, SER634G
• G-K: ALA311G, ARG314G, ARG323K, ASP632K, ASP633K, CYS310G, GLU321G, GLU322G, GLU322K, GLY328G, HIS329G, ILE331G, LEU631K, LYS318G, LYS635K, PHE628K, PRO319K, SER634K, TRP636K
• G-L: ALA149L, ALA151L, ALA281G, ALA292G, ALA299G, ALA301G, ALA311G, ALA378G, ALA76G, ARG157G, ARG160G, ARG167L, ARG282G, ARG314G, ARG336G, ARG91G, ASN136G, ASN166L, ASN303G, ASN337G, ASN78G, ASN84G, ASP150L, ASP159L, ASP308G, ASP381G, ASP96G, CYS156L, CYS162L, CYS310G, GLN155L, GLN162G, GLU152L, GLU163L, GLU307G, GLU377G, GLU380G, GLY134G, GLY159G, GLY164L, GLY165L, GLY291G, GLY328G, HIS329G, HIS418G, HIS469G, ILE129G, ILE148L, ILE163G, ILE165G, ILE331G, ILE351G, ILE407G, ILE77G, LEU160L, LEU295G, LEU296G, LEU317G, LEU374G, LYS130G, LYS154G, LYS298G, LYS300G, LYS327G, LYS470G, MET164G, MET339G, MET340G, MET353G, MET408G, MET92G, PHE158L, PHE278G, PHE283G, PHE294G, PHE297G, PHE471G, PHE622G, PRO155G, PRO161L, PRO280G, PRO289G, PRO332G, PRO409G, SER154L, SER158G, SER419G, SER75G, THR153L, THR302G, THR312G, THR333G, THR79G, THR95G, TRP128G, TRP157L, TRP161G, TRP251G, TRP293G, TRP379G, TYR309G, TYR352G, TYR80G, TYR89G, VAL156G, VAL290G, VAL330G, VAL93G
• H-I: ALA149H, ALA151H, ALA281I, ALA292I, ALA299I, ALA301I, ALA311I, ALA378I, ALA76I, ARG157I, ARG160I, ARG167H, ARG282I, ARG314I, ARG336I, ASN136I, ASN166H, ASN303I, ASN337I, ASN78I, ASN84I, ASP131I, ASP150H, ASP153I, ASP159H, ASP308I, ASP381I, ASP96I, CYS156H, CYS162H, CYS310I, GLN155H, GLN162I, GLU152H, GLU163H, GLU307I, GLU377I, GLU380I, GLY134I, GLY159I, GLY164H, GLY165H, GLY291I, GLY328I, HIS135I, HIS329I, HIS418I, HIS469I, ILE129I, ILE148H, ILE163I, ILE165I, ILE331I, ILE351I, ILE407I, ILE77I, LEU137I, LEU160H, LEU295I, LEU296I, LEU374I, LEU97I, LYS130I, LYS154I, LYS298I, LYS300I, LYS327I, MET164I, MET339I, MET340I, MET353I, MET408I, MET92I, PHE158H, PHE278I, PHE294I, PHE471I, PHE622I, PRO155I, PRO161H, PRO280I, PRO289I, PRO332I, PRO409I, SER154H, SER158I, SER419I, SER75I, THR153H, THR302I, THR312I, THR333I, THR79I, THR95I, TRP128I, TRP157H, TRP161I, TRP251I, TRP293I, TRP379I, TYR309I, TYR352I, TYR80I, TYR89I, VAL156I, VAL279I, VAL290I, VAL330I, VAL93I
• I-J: ALA121J, ALA134J, ALA140I, ALA141J, ALA142I, ALA144I, ALA146J, ALA149J, ALA14I, ALA151J, ALA175I, ALA177I, ALA178I, ALA181I, ALA20J, ALA250I, ALA376I, ALA378I, ALA390I, ALA394I, ALA395I, ALA399I, ALA40I, ALA432I, ALA43I, ALA46J, ALA477I, ALA47I, ALA51I, ALA62I, ALA64J, ALA68J, ALA69I, ALA71I, ALA71J, ALA86I, ARG105J, ARG111I, ARG11I, ARG150I, ARG186I, ARG190I, ARG215I, ARG241I, ARG249I, ARG403I, ARG450I, ARG45I, ARG480I, ARG488I, ARG593I, ARG600I, ARG614I, ARG618I, ARG65J, ARG66I, ARG81J, ARG91I, ARG93J, ARG94I, ARG99J, ASN126J, ASN166I, ASN180I, ASN236I, ASN256I, ASN27J, ASN391I, ASN397I, ASN41J, ASN449I, ASN84I, ASN85I, ASN94J, ASP104I, ASP108I, ASP114I, ASP115I, ASP123J, ASP138I, ASP150J, ASP285I, ASP28J, ASP33J, ASP381I, ASP384I, ASP430I, ASP437I, ASP48I, ASP492I, ASP587I, ASP60I, ASP632I, ASP633I, ASP664I, ASP69J, ASP85J, ASP87I, ASP88I, CYS21J, CYS25J, CYS386I, CYS398I, CYS47J, CYS50J, CYS53J, CYS638I, CYS77J, GLN139J, GLN141I, GLN144J, GLN147J, GLN155J, GLN389I, GLN42J, GLN485I, GLN660I, GLN72I, GLU103I, GLU109J, GLU116J, GLU120J, GLU121I, GLU122I, GLU125J, GLU127J, GLU132J, GLU152J, GLU163J, GLU168I, GLU176I, GLU189I, GLU245I, GLU35J, GLU375I, GLU377I, GLU380I, GLU401I, GLU402I, GLU42I, GLU431I, GLU43J, GLU45J, GLU478I, GLU49J, GLU590I, GLU596I, GLU615I, GLU65I, GLU84J, GLY110I, GLY110J, GLY117J, GLY122J, GLY124I, GLY12I, GLY139I, GLY143J, GLY167I, GLY183I, GLY244I, GLY246I, GLY248I, GLY286I, GLY388I, GLY38I, GLY428I, GLY479I, GLY483I, GLY68I, GLY73I, GLY74J, GLY75J, GLY82J, GLY95J, HIS112I, HIS118I, HIS373I, HIS476I, HIS589I, ILE104J, ILE112J, ILE148J, ILE165I, ILE173I, ILE187I, ILE24J, ILE31J, ILE481I, ILE54J, ILE56J, ILE661I, ILE662I, ILE78J, ILE86J, ILE90J, LEU100I, LEU119I, LEU124J, LEU125I, LEU128J, LEU129J, LEU135J, LEU137I, LEU142J, LEU182I, LEU214I, LEU29J, LEU32J, LEU359I, LEU374I, LEU383I, LEU392I, LEU491I, LEU588I, LEU592I, LEU64I, LEU74I, LEU81I, LYS101J, LYS113J, LYS118J, LYS143I, LYS145J, LYS171I, LYS179I, LYS18J, LYS284I, LYS372I, LYS446I, LYS484I, LYS49I, LYS538I, LYS55J, LYS61I, LYS635I, LYS637I, LYS655I, LYS656I, LYS91J, LYS98J, MET22J, MET247I, MET30J, MET385I, MET486I, MET541I, MET542I, MET73J, MET87J, PHE100J, PHE102J, PHE115J, PHE120I, PHE130J, PHE212I, PHE363I, PHE382I, PHE40J, PHE41I, PHE613I, PHE628I, PHE639I, PHE70J, PHE92J, PRO103J, PRO108J, PRO10I, PRO114J, PRO119J, PRO126I, PRO138J, PRO240I, PRO253I, PRO26J, PRO2J, PRO34J, PRO400I, PRO429I, PRO435I, PRO44J, PRO537I, PRO657I, PRO663I, PRO66J, PRO72J, PRO79J, SER111J, SER116I, SER154J, SER169I, SER242I, SER52J, SER634I, SER63I, SER67I, SER83J, SER96J, THR106J, THR107J, THR131J, THR133J, THR136J, THR153J, THR19J, THR396I, THR3J, THR63J, THR76J, THR89J, THR9I, TRP123I, TRP128I, TRP251I, TRP255I, TRP293I, TRP379I, TRP393I, TRP433I, TRP46I, TRP489I, TRP48J, TRP636I, TRP88J, TYR107I, TYR170I, TYR23J, TYR252I, TYR287I, TYR413I, TYR438I, TYR448I, TYR490I, TYR50I, TYR51J, TYR658I, TYR659I, TYR67J, VAL113I, VAL127I, VAL137J, VAL13I, VAL140J, VAL172I, VAL174I, VAL235I, VAL243I, VAL254I, VAL387I, VAL434I, VAL447I, VAL44I, VAL482I, VAL487I, VAL70I, VAL90I, VAL97J
• I-K: ALA311K, ARG314K, ARG323I, ARG323K, ASP308K, ASP632I, ASP633I, GLU321K, GLU322I, GLU322K, GLY324K, GLY328K, GLY630I, HIS329K, ILE331K, LEU629I, LEU631I, LYS318I, LYS318K, LYS327K, LYS635I, LYS637I, PHE628I, PRO319I, SER634I, TYR325I, VAL330K
• J-K: ALA149J, ALA151J, ALA281K, ALA292K, ALA299K, ALA301K, ALA311K, ALA378K, ALA76K, ARG157K, ARG160K, ARG167J, ARG282K, ARG314K, ARG336K, ASN136K, ASN166J, ASN303K, ASN337K, ASN78K, ASN84K, ASP150J, ASP159J, ASP308K, ASP381K, ASP96K, CYS156J, CYS162J, CYS310K, GLN147J, GLN155J, GLN162K, GLU152J, GLU163J, GLU307K, GLU377K, GLU380K, GLY134K, GLY159K, GLY164J, GLY165J, GLY291K, HIS135K, HIS329K, HIS373K, HIS418K, HIS469K, ILE163K, ILE165K, ILE331K, ILE351K, ILE407K, ILE77K, LEU160J, LEU295K, LEU296K, LEU317K, LEU374K, LEU97K, LYS130K, LYS154K, LYS298K, LYS300K, LYS470K, MET164K, MET339K, MET340K, MET353K, MET385K, MET408K, MET92K, PHE158J, PHE278K, PHE283K, PHE294K, PHE471K, PHE622K, PRO155K, PRO161J, PRO280K, PRO289K, PRO332K, PRO409K, SER154J, SER158K, SER419K, SER75K, THR153J, THR302K, THR333K, THR79K, THR95K, TRP128K, TRP157J, TRP161K, TRP251K, TRP293K, TRP379K, TYR309K, TYR352K, TYR80K, TYR89K, VAL156K, VAL279K, VAL290K, VAL330K, VAL93K
• K-L: ALA121L, ALA134L, ALA140K, ALA141L, ALA142K, ALA144K, ALA146L, ALA149L, ALA14K, ALA151L, ALA175K, ALA177K, ALA178K, ALA181K, ALA20L, ALA250K, ALA257K, ALA376K, ALA378K, ALA390K, ALA394K, ALA395K, ALA399K, ALA40K, ALA432K, ALA43K, ALA46L, ALA477K, ALA47K, ALA51K, ALA62K, ALA64L, ALA68L, ALA69K, ALA71K, ALA71L, ALA86K, ARG105L, ARG111K, ARG11K, ARG150K, ARG186K, ARG190K, ARG215K, ARG241K, ARG249K, ARG403K, ARG450K, ARG45K, ARG480K, ARG488K, ARG593K, ARG600K, ARG614K, ARG65L, ARG66K, ARG81L, ARG91K, ARG93L, ARG94K, ARG99L, ASN126L, ASN166K, ASN180K, ASN236K, ASN256K, ASN27L, ASN391K, ASN397K, ASN41L, ASN449K, ASN84K, ASN85K, ASN94L, ASP104K, ASP108K, ASP114K, ASP115K, ASP123L, ASP138K, ASP150L, ASP285K, ASP28L, ASP33L, ASP381K, ASP384K, ASP430K, ASP437K, ASP48K, ASP492K, ASP587K, ASP60K, ASP632K, ASP633K, ASP664K, ASP69L, ASP85L, ASP87K, ASP88K, CYS21L, CYS25L, CYS386K, CYS398K, CYS47L, CYS50L, CYS53L, CYS638K, CYS77L, GLN139L, GLN141K, GLN144L, GLN147L, GLN389K, GLN42L, GLN485K, GLN660K, GLN72K, GLU103K, GLU109L, GLU116L, GLU120L, GLU121K, GLU122K, GLU125L, GLU127L, GLU132L, GLU152L, GLU168K, GLU176K, GLU189K, GLU245K, GLU375K, GLU377K, GLU380K, GLU401K, GLU402K, GLU42K, GLU431K, GLU43L, GLU45L, GLU478K, GLU49L, GLU590K, GLU596K, GLU615K, GLU65K, GLU84L, GLY110K, GLY110L, GLY117L, GLY122L, GLY124K, GLY12K, GLY139K, GLY143L, GLY167K, GLY183K, GLY244K, GLY246K, GLY248K, GLY286K, GLY388K, GLY38K, GLY428K, GLY479K, GLY483K, GLY68K, GLY73K, GLY74L, GLY75L, GLY82L, GLY95L, HIS112K, HIS118K, HIS373K, HIS476K, HIS589K, ILE104L, ILE112L, ILE148L, ILE165K, ILE173K, ILE24L, ILE31L, ILE481K, ILE54L, ILE56L, ILE661K, ILE662K, ILE78L, ILE86L, ILE90L, LEU100K, LEU119K, LEU124L, LEU125K, LEU128L, LEU129L, LEU135L, LEU137K, LEU142L, LEU182K, LEU214K, LEU29L, LEU32L, LEU359K, LEU374K, LEU383K, LEU392K, LEU491K, LEU588K, LEU592K, LEU64K, LEU74K, LEU81K, LYS101L, LYS113L, LYS118L, LYS143K, LYS145L, LYS171K, LYS179K, LYS18L, LYS284K, LYS372K, LYS446K, LYS484K, LYS49K, LYS538K, LYS55L, LYS61K, LYS635K, LYS637K, LYS655K, LYS656K, LYS91L, LYS98L, MET22L, MET247K, MET30L, MET385K, MET486K, MET541K, MET542K, MET73L, MET87L, PHE100L, PHE102L, PHE115L, PHE120K, PHE130L, PHE192K, PHE212K, PHE363K, PHE382K, PHE40L, PHE41K, PHE613K, PHE639K, PHE654K, PHE70L, PHE92L, PRO103L, PRO108L, PRO10K, PRO114L, PRO119L, PRO126K, PRO138L, PRO240K, PRO253K, PRO26L, PRO2L, PRO34L, PRO400K, PRO429K, PRO435K, PRO44L, PRO537K, PRO657K, PRO663K, PRO66L, PRO72L, PRO79L, SER111L, SER116K, SER154L, SER169K, SER242K, SER52L, SER634K, SER63K, SER67K, SER83L, SER96L, THR106L, THR107L, THR131L, THR133L, THR136L, THR153L, THR19L, THR396K, THR3L, THR63L, THR76L, THR89L, THR9K, TRP123K, TRP128K, TRP251K, TRP255K, TRP293K, TRP379K, TRP393K, TRP433K, TRP46K, TRP489K, TRP48L, TRP636K, TRP88L, TYR107K, TYR170K, TYR23L, TYR252K, TYR287K, TYR438K, TYR448K, TYR490K, TYR50K, TYR51L, TYR658K, TYR659K, TYR67L, VAL113K, VAL127K, VAL137L, VAL13K, VAL140L, VAL172K, VAL174K, VAL235K, VAL243K, VAL254K, VAL387K, VAL434K, VAL447K, VAL44K, VAL482K, VAL487K, VAL70K, VAL90K, VAL97L