3GVP

human sahh-like domain of human adenosylhomocysteinase 3

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 195
  • Norm. En. per Res.: -4.1886
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-49.8175	11.3225	-223.02	-261.515	148	7	2	10284	2	56	43
A-C	-103.0401	-66.4347	-647.311	-816.7858	195	35	24	25469	8	53	43
A-D	-5.3935	1.5107	-135.849	-139.7317	60	5	0	5020	0	8	7
B-C	-6.4326	3.1416	-129.456	-132.747	58	2	0	4905	0	8	7
B-D	-95.9342	-63.4729	-664.534	-823.9412	199	28	25	26154	7	53	40
C-D	-70.7433	-21.1803	-235.5	-327.4236	148	10	1	10794	2	62	47

Interface residues

• A-B: ALA204A, ALA409A, ALA409B, ALA410A, ALA410B, ALA413A, ALA413B, ALA583A, ALA583B, ARG199A, ARG199B, ARG375A, ARG375B, ARG384A, ARG384B, ARG446A, ARG446B, ARG501A, ARG501B, ARG514A, ARG514B, ASN471A, ASN471B, ASP380A, ASP380B, ASP387A, ASP387B, ASP449A, ASP449B, ASP582A, ASP582B, CYS373A, CYS373B, CYS407A, CYS528A, CYS528B, GLN206A, GLN206B, GLN238A, GLN238B, GLN394A, GLN394B, GLN447A, GLN447B, GLU200A, GLU200B, GLU202A, GLU202B, GLU205A, GLU207A, GLU207B, GLU376A, GLU376B, GLU498A, GLU498B, GLY381A, GLY381B, GLY391A, GLY391B, GLY392A, GLY392B, GLY406A, GLY406B, GLY415A, GLY415B, GLY512A, GLY512B, HIS506A, HIS506B, HIS577B, HIS584A, HIS584B, ILE203A, ILE203B, ILE378A, ILE378B, ILE417A, ILE417B, ILE474B, ILE508A, ILE538A, ILE538B, LEU379A, LEU379B, LEU411A, LEU411B, LEU536A, LYS383A, LYS383B, LYS393A, LYS393B, LYS412A, LYS412B, LYS470A, LYS470B, LYS513B, MET208A, MET388A, MET388B, MET389A, MET389B, MET414A, MET414B, PHE368A, PHE368B, PHE390A, PHE390B, PHE534A, PHE534B, PHE581A, PHE581B, PRO209A, PRO532A, PRO532B, PRO579A, PRO579B, SER377A, SER377B, SER416A, SER416B, SER472A, SER472B, SER529A, SER529B, THR385A, THR385B, THR386A, THR386B, THR530A, THR530B, THR533A, THR533B, THR580A, THR580B, TYR372A, TYR372B, TYR419A, TYR419B, VAL448A, VAL448B, VAL500A, VAL500B, VAL516A, VAL516B, VAL531A, VAL531B, VAL535A, VAL535B
• A-C: ALA428A, ALA428C, ALA431A, ALA431C, ALA574A, ALA574C, ALA583A, ALA583C, ALA593A, ALA593C, ARG375A, ARG375C, ARG437A, ARG437C, ASN442A, ASN442C, ASN457A, ASN457C, ASN459A, ASN459C, ASN482A, ASN482C, ASN599A, ASN599C, ASN601A, ASN601C, ASP424A, ASP424C, ASP434A, ASP434C, ASP570A, ASP570C, ASP582A, ASP582C, ASP590C, CYS398A, CYS398C, CYS427A, CYS427C, CYS432A, CYS432C, GLN430A, GLN430C, GLN592A, GLN592C, GLU376A, GLU376C, GLU402A, GLU402C, GLU422A, GLU422C, GLU443A, GLU443C, GLU484A, GLU484C, GLU571A, GLU571C, GLU587A, GLU587C, GLU591A, GLU591C, GLY399A, GLY399C, GLY401A, GLY401C, GLY435A, GLY435C, GLY456A, GLY456C, GLY597C, GLY602A, GLY602C, HIS341A, HIS465A, HIS465C, HIS480A, HIS480C, HIS577A, HIS577C, HIS584A, HIS584C, ILE423A, ILE423C, ILE426A, ILE426C, ILE538A, ILE538C, LEU371A, LEU371C, LEU429A, LEU429C, LEU438A, LEU438C, LEU441A, LEU441C, LEU565A, LEU565C, LEU576A, LEU576C, LEU578A, LEU578C, LEU585A, LEU585C, LEU588A, LEU588C, LEU596A, LEU596C, LEU598A, LEU598C, LYS365A, LYS365C, LYS367A, LYS367C, LYS405A, LYS405C, LYS412C, LYS440A, LYS440C, LYS458A, LYS458C, LYS567A, LYS567C, LYS568A, LYS568C, LYS594C, LYS600A, LYS600C, LYS605A, LYS605C, MET433A, MET433C, MET569A, MET569C, PHE368A, PHE368C, PHE436A, PHE436C, PHE534A, PHE534C, PHE581A, PHE581C, PHE604A, PHE604C, PRO425A, PRO425C, PRO566A, PRO566C, PRO579A, PRO579C, PRO603A, PRO603C, SER362A, SER362C, SER481A, SER481C, SER575A, SER575C, THR364A, THR364C, THR421A, THR421C, THR455A, THR455C, THR462A, THR462C, THR483A, THR483C, THR580A, THR580C, THR586A, THR586C, THR589A, THR589C, TYR372A, TYR372C, TYR400A, TYR400C, TYR572A, TYR572C, TYR595A, TYR595C, VAL363A, VAL363C, VAL420A, VAL420C, VAL439A, VAL439C, VAL460A, VAL460C, VAL461A, VAL461C, VAL535A, VAL535C, VAL573A, VAL573C
• A-D: ALA413A, ALA413D, ALA431A, ALA431D, ARG437A, ARG437D, ASP434A, ASP434D, ASP449A, ASP449D, CYS432A, CYS432D, GLN394A, GLN394D, GLN447A, GLN447D, GLY391A, GLY391D, GLY392A, GLY392D, GLY415A, GLY415D, GLY435A, GLY435D, ILE417A, ILE417D, LEU411A, LEU411D, LEU429A, LEU429D, LEU438A, LEU438D, LYS393A, LYS393D, LYS412A, LYS412D, LYS470A, LYS470D, MET389A, MET389D, MET414A, MET414D, MET433A, MET433D, PHE390A, PHE390D, PHE436A, PHE436D, SER416A, SER416D, TYR419A, TYR419D, VAL395A, VAL395D, VAL418A, VAL418D, VAL444A, VAL444D, VAL448A, VAL448D
• B-C: ALA413B, ALA413C, ALA431B, ALA431C, ARG437B, ARG437C, ASP434B, ASP434C, ASP449B, CYS432B, CYS432C, GLN394B, GLN394C, GLN447B, GLN447C, GLY391B, GLY391C, GLY392B, GLY392C, GLY415B, GLY415C, GLY435B, GLY435C, ILE417B, ILE417C, LEU411B, LEU411C, LEU429B, LEU429C, LEU438B, LEU438C, LYS393B, LYS393C, LYS412B, LYS412C, LYS470B, MET389B, MET389C, MET414B, MET414C, MET433B, MET433C, PHE390B, PHE390C, PHE436B, PHE436C, SER416B, SER416C, TYR419B, TYR419C, VAL395B, VAL395C, VAL418B, VAL418C, VAL444B, VAL444C, VAL448B, VAL448C
• B-D: ALA428B, ALA428D, ALA431B, ALA431D, ALA574B, ALA574D, ALA583B, ALA583D, ALA593B, ALA593D, ARG375B, ARG375D, ARG437B, ARG437D, ASN442B, ASN442D, ASN457B, ASN457D, ASN459B, ASN459D, ASN482B, ASN482D, ASN599B, ASN599D, ASN601B, ASN601D, ASP424B, ASP424D, ASP434B, ASP434D, ASP570B, ASP570D, ASP582B, ASP582D, ASP590B, ASP590D, CYS373B, CYS398B, CYS398D, CYS427B, CYS427D, CYS432B, CYS432D, GLN430B, GLN430D, GLN592B, GLN592D, GLU376B, GLU376D, GLU402B, GLU402D, GLU422B, GLU422D, GLU443B, GLU443D, GLU484B, GLU484D, GLU571B, GLU571D, GLU587B, GLU587D, GLU591B, GLU591D, GLY399B, GLY399D, GLY401B, GLY401D, GLY435B, GLY435D, GLY456B, GLY456D, GLY597D, GLY602B, GLY602D, HIS341B, HIS465B, HIS465D, HIS480B, HIS480D, HIS577B, HIS577D, HIS584B, HIS584D, ILE423B, ILE423D, ILE426B, ILE426D, ILE538B, ILE538D, LEU371B, LEU371D, LEU429B, LEU429D, LEU438B, LEU438D, LEU441B, LEU441D, LEU565B, LEU565D, LEU576B, LEU576D, LEU578B, LEU578D, LEU585B, LEU585D, LEU588B, LEU588D, LEU596B, LEU596D, LEU598B, LEU598D, LYS365B, LYS365D, LYS367B, LYS367D, LYS405B, LYS405D, LYS412D, LYS440B, LYS440D, LYS458B, LYS458D, LYS567B, LYS567D, LYS568B, LYS568D, LYS594B, LYS594D, LYS600B, LYS600D, LYS605B, LYS605D, MET433B, MET433D, MET569B, MET569D, PHE368B, PHE368D, PHE436B, PHE436D, PHE534B, PHE534D, PHE581B, PHE581D, PHE604B, PHE604D, PRO425B, PRO425D, PRO532B, PRO566B, PRO566D, PRO579B, PRO579D, PRO603B, PRO603D, SER362B, SER362D, SER481B, SER481D, SER575B, SER575D, THR364B, THR364D, THR421B, THR421D, THR455B, THR455D, THR462B, THR462D, THR483B, THR483D, THR580B, THR580D, THR586B, THR586D, THR589B, THR589D, TYR372B, TYR372D, TYR400B, TYR400D, TYR572B, TYR572D, TYR595B, TYR595D, VAL363B, VAL363D, VAL420B, VAL420D, VAL439B, VAL439D, VAL460B, VAL460D, VAL461B, VAL461D, VAL535B, VAL535D, VAL573B, VAL573D
• C-D: ALA204C, ALA204D, ALA409C, ALA409D, ALA410C, ALA410D, ALA413C, ALA413D, ALA583C, ALA583D, ARG199C, ARG199D, ARG375C, ARG375D, ARG384C, ARG384D, ARG446C, ARG446D, ARG499C, ARG501C, ARG501D, ARG514C, ARG514D, ASN471C, ASN471D, ASP380C, ASP380D, ASP387C, ASP387D, ASP449C, ASP449D, ASP582C, ASP582D, CYS373C, CYS373D, CYS528C, GLN206C, GLN206D, GLN238D, GLN394C, GLN394D, GLN447C, GLN447D, GLU200C, GLU200D, GLU202C, GLU202D, GLU205D, GLU207C, GLU207D, GLU376C, GLU376D, GLU498C, GLU498D, GLY381C, GLY381D, GLY391C, GLY391D, GLY392C, GLY392D, GLY406C, GLY406D, GLY415C, GLY415D, GLY512C, GLY512D, HIS506C, HIS506D, HIS577C, HIS584D, ILE203C, ILE203D, ILE378C, ILE417C, ILE417D, ILE474C, ILE474D, ILE508C, ILE508D, ILE538C, ILE538D, LEU379C, LEU379D, LEU411C, LEU411D, LYS383C, LYS383D, LYS393C, LYS393D, LYS412C, LYS412D, LYS470C, LYS470D, LYS513C, LYS513D, MET208D, MET388C, MET388D, MET389C, MET389D, MET414C, MET414D, PHE196D, PHE368C, PHE368D, PHE390C, PHE390D, PHE534C, PHE534D, PHE581C, PHE581D, PRO209D, PRO532C, PRO532D, PRO579C, PRO579D, SER377C, SER377D, SER416C, SER416D, SER472C, SER472D, SER529C, SER529D, THR385C, THR385D, THR386C, THR386D, THR530C, THR530D, THR533C, THR533D, THR580C, THR580D, TYR372C, TYR372D, TYR419C, TYR419D, VAL448C, VAL448D, VAL500C, VAL500D, VAL516C, VAL516D, VAL531C, VAL531D, VAL535C, VAL535D