3GUA

sulfates bound in the vestibule of achbp

• Total interactions analyzed: 45
• Total true interactions: 25
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 139
  • Norm. En. per Res.: -3.4482
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-44.9189	-29.6316	-359.386	-433.9366	137	19	2	14452	4	36	35
A-E	-70.7562	-59.4764	-349.074	-479.3066	139	21	2	14603	4	37	34
A-H	-3.4599	-31.4477	-86.0363	-120.9439	47	1	1	3039	2	24	32
A-I	0.0	12.2185	-43.9329	-31.7144	35	4	0	2286	0	15	16
A-J	0.0	0.0	-0.0023	-0.0023	4	0	0	6	0	0	0
B-C	-48.7179	-30.7573	-339.995	-419.4702	137	22	2	13956	3	38	34
B-G	-2.3758	-34.6979	-98.8835	-135.9572	47	4	1	3378	4	24	34
B-H	-3.4331	12.581	-44.5881	-35.4401	36	5	0	2553	0	16	16
B-I	0.0	0.0	-0.0107	-0.0107	4	0	0	12	0	0	0
C-D	-51.2623	-60.3123	-347.601	-459.1755	140	23	2	14553	5	39	34
C-F	-13.8088	-34.9486	-99.1579	-147.9153	48	4	1	3443	4	24	34
C-G	0.0	13.9786	-56.6306	-42.652	41	6	0	2717	0	16	16
C-H	0.0	0.0	-0.0123	-0.0123	4	0	0	12	0	0	0
D-E	-34.5781	-53.1737	-355.517	-443.2688	135	15	2	14293	5	38	35
D-F	0.0	12.479	-43.4975	-31.0185	36	4	0	2481	0	15	16
D-G	0.0	0.0	-0.0122	-0.0122	4	0	0	12	0	0	0
D-J	-5.4491	-27.9794	-84.6997	-118.1282	46	2	1	3036	2	24	33
E-F	0.0	0.0	-0.01	-0.01	4	0	0	10	0	0	0
E-I	-7.0381	-31.3077	-78.1588	-116.5047	41	2	1	2897	4	24	34
E-J	0.0	11.6359	-45.0813	-33.4454	35	2	0	2294	0	16	16
F-G	-44.5598	-23.1445	-345.467	-413.1713	134	22	2	14107	4	37	34
F-J	-58.8277	-60.9629	-353.469	-473.2596	138	24	2	14470	5	37	35
G-H	-38.9662	-43.2874	-358.849	-441.1026	139	19	2	14487	3	38	35
H-I	-35.547	-47.5624	-345.255	-428.3644	134	14	2	14046	4	38	35
I-J	-48.6311	-65.3079	-368.221	-482.16	140	20	2	14585	6	38	34

Interface residues

• A-B: ALA107A, ALA120A, ALA141B, ALA170A, ALA43A, ALA4A, ALA82A, ALA92B, ARG122A, ARG16B, ARG207A, ARG79A, ARG8A, ARG97A, ARG97B, ASN48B, ASN5A, ASN63B, ASN74A, ASP-2A, ASP-3A, ASP-4A, ASP-5A, ASP-8A, ASP128B, ASP26B, ASP27B, ASP39A, ASP44B, ASP51A, ASP77A, ASP89B, CYS127B, CYS140B, GLN100A, GLN100B, GLN105A, GLN121A, GLN38A, GLN3A, GLU153B, GLU193B, GLU49B, GLU56A, GLY145B, GLY151B, GLY22B, GLY73A, HIS1A, ILE106A, ILE118A, ILE154B, ILE40A, ILE75A, ILE90B, LEU0A, LEU102A, LEU123A, LEU123B, LEU29B, LEU37A, LEU52A, LEU62B, LEU6A, LYS-1A, LYS10A, LYS143B, LYS173A, LYS25B, LYS42A, MET116A, MET126B, MET19B, MET66B, MET7A, PHE117A, PHE125B, PHE152B, PHE78A, PRO104A, PRO119A, PRO129B, PRO18B, PRO21B, PRO23B, PRO28B, PRO88B, PRO98A, PRO98B, SER103A, SER11A, SER124A, SER124B, SER146B, SER150B, SER166A, SER167A, SER171A, SER172A, SER17B, SER2A, SER45B, SER46B, SER64B, SER81A, SER94B, SER95B, THR130B, THR139B, THR24B, THR47B, THR76A, THR80A, THR87B, THR91B, THR96B, TRP147B, TRP86B, TYR-7A, TYR149B, TYR168A, TYR169A, TYR174A, TYR188B, TYR195B, TYR20B, TYR54A, TYR55A, TYR93B, VAL101A, VAL108A, VAL142B, VAL148B, VAL41A, VAL53A, VAL99A, VAL99B
• A-E: ALA107E, ALA120E, ALA141A, ALA170E, ALA43E, ALA4E, ALA82E, ALA92A, ARG122E, ARG16A, ARG207E, ARG79E, ARG8E, ARG97A, ARG97E, ASN48A, ASN5E, ASN63A, ASN74E, ASP-2E, ASP-3E, ASP-4E, ASP-5E, ASP-8E, ASP128A, ASP26A, ASP27A, ASP39E, ASP44A, ASP51E, ASP77E, ASP89A, CYS127A, CYS140A, CYS190A, CYS191A, GLN100A, GLN100E, GLN105E, GLN121E, GLN38E, GLN3E, GLU153A, GLU193A, GLU49A, GLU56E, GLY145A, GLY151A, GLY22A, GLY73E, HIS1E, ILE106E, ILE118E, ILE154A, ILE40E, ILE75E, ILE90A, LEU0E, LEU102E, LEU123A, LEU123E, LEU37E, LEU52E, LEU62A, LEU6E, LYS-1E, LYS10E, LYS143A, LYS173E, LYS25A, LYS42E, MET116E, MET126A, MET19A, MET66A, MET7E, PHE117E, PHE125A, PHE152A, PHE78E, PRO104E, PRO119E, PRO129A, PRO18A, PRO21A, PRO23A, PRO28A, PRO88A, PRO98A, PRO98E, SER103E, SER124A, SER124E, SER146A, SER150A, SER166E, SER167E, SER171E, SER172E, SER17A, SER2E, SER45A, SER46A, SER64A, SER81E, SER94A, SER95A, THR130A, THR139A, THR24A, THR36E, THR47A, THR76E, THR80E, THR87A, THR91A, THR96A, TRP147A, TRP86A, TYR-7E, TYR149A, TYR168E, TYR169E, TYR174E, TYR188A, TYR195A, TYR20A, TYR54E, TYR55E, TYR93A, VAL101E, VAL108E, VAL109E, VAL142A, VAL148A, VAL41E, VAL53E, VAL99A, VAL99E
• A-H: ALA4A, ALA4H, ARG8A, ARG8H, ASN5A, ASN5H, ASN70A, ASN70H, ASN74A, ASN74H, ASP-2A, ASP-2H, ASP-3A, ASP-3H, ASP-4A, ASP-4H, ASP-8A, ASP-8H, ASP12A, ASP12H, ASP68A, ASP68H, GLN3A, GLN3H, GLU71A, GLU71H, GLY73A, GLY73H, HIS1A, HIS1H, ILE75H, LEU0A, LEU0H, LYS-1A, LYS-1H, LYS-6A, LYS-6H, MET7A, MET7H, PRO69A, PRO69H, SER2A, SER2H, TYR-7A, TYR-7H, TYR72A, TYR72H
• A-I: ALA4A, ALA4I, ARG16A, ARG16I, ARG8A, ARG8I, ASN15A, ASN15I, ASN5A, ASN5I, ASP12A, ASP12I, ASP68A, ASP68I, GLU71A, GLU71I, LEU13A, LEU13I, LEU9A, LEU9I, LYS10A, LYS10I, MET19A, MET19I, MET7A, MET7I, PHE14I, PRO18A, PRO18I, SER11A, SER11I, SER17A, SER17I, TYR72A, TYR72I
• A-J: PRO18A, PRO18J, SER17A, SER17J
• B-C: ALA107B, ALA120B, ALA141C, ALA170B, ALA43B, ALA4B, ALA82B, ALA92C, ARG122B, ARG16C, ARG207B, ARG79B, ARG8B, ARG97B, ARG97C, ASN48C, ASN5B, ASN63C, ASN74B, ASP-2B, ASP-3B, ASP-4B, ASP-5B, ASP-8B, ASP128C, ASP26C, ASP27C, ASP39B, ASP44C, ASP51B, ASP77B, ASP89C, CYS127C, CYS140C, GLN100B, GLN100C, GLN105B, GLN121B, GLN38B, GLN3B, GLU153C, GLU193C, GLU49C, GLU56B, GLY145C, GLY151C, GLY22C, GLY73B, HIS1B, ILE106B, ILE118B, ILE154C, ILE40B, ILE75B, ILE90C, LEU0B, LEU102B, LEU123B, LEU123C, LEU29C, LEU37B, LEU52B, LEU62C, LEU6B, LYS-1B, LYS10B, LYS143C, LYS173B, LYS25C, LYS42B, MET116B, MET126C, MET19C, MET66C, MET7B, PHE117B, PHE125C, PHE152C, PHE78B, PRO104B, PRO119B, PRO129C, PRO18C, PRO21C, PRO23C, PRO28C, PRO88C, PRO98B, PRO98C, SER103B, SER124B, SER124C, SER146C, SER150C, SER166B, SER167B, SER171B, SER172B, SER17C, SER2B, SER45C, SER46C, SER64C, SER81B, SER94C, SER95C, THR130C, THR139C, THR24C, THR47C, THR76B, THR80B, THR87C, THR91C, THR96C, TRP147C, TRP86C, TYR-7B, TYR149C, TYR168B, TYR169B, TYR174B, TYR188C, TYR195C, TYR20C, TYR54B, TYR55B, TYR93C, VAL101B, VAL108B, VAL142C, VAL148C, VAL41B, VAL50C, VAL53B, VAL99B, VAL99C
• B-G: ALA4B, ALA4G, ARG8B, ARG8G, ASN5B, ASN5G, ASN70B, ASN70G, ASN74B, ASN74G, ASP-2B, ASP-2G, ASP-3B, ASP-3G, ASP-4B, ASP-4G, ASP-8B, ASP-8G, ASP12B, ASP68B, ASP68G, GLN3B, GLN3G, GLU71B, GLU71G, GLY73B, GLY73G, HIS1B, HIS1G, ILE75B, ILE75G, LEU0B, LEU0G, LYS-1B, LYS-1G, LYS-6B, LYS-6G, MET7B, MET7G, PRO69B, PRO69G, SER2B, SER2G, TYR-7B, TYR-7G, TYR72B, TYR72G
• B-H: ALA4B, ALA4H, ARG16B, ARG16H, ARG8B, ARG8H, ASN15B, ASN15H, ASN5B, ASN5H, ASP12B, ASP12H, ASP68B, ASP68H, GLU71B, GLU71H, LEU13B, LEU13H, LEU6H, LEU9B, LEU9H, LYS10B, LYS10H, MET19B, MET19H, MET7B, MET7H, PHE14H, PRO18B, PRO18H, SER11B, SER11H, SER17B, SER17H, TYR72B, TYR72H
• B-I: PRO18B, PRO18I, SER17B, SER17I
• C-D: ALA107C, ALA120C, ALA141D, ALA170C, ALA43C, ALA4C, ALA82C, ALA92D, ARG122C, ARG16D, ARG207C, ARG79C, ARG8C, ARG97C, ARG97D, ASN48D, ASN5C, ASN63D, ASN74C, ASP-2C, ASP-3C, ASP-4C, ASP-5C, ASP-8C, ASP128D, ASP26D, ASP27D, ASP39C, ASP44D, ASP51C, ASP77C, ASP89D, CYS127D, CYS140D, CYS190D, CYS191D, GLN100C, GLN100D, GLN105C, GLN121C, GLN38C, GLN3C, GLU153D, GLU193D, GLU49D, GLU56C, GLY145D, GLY151D, GLY22D, GLY73C, HIS1C, ILE106C, ILE118C, ILE154D, ILE40C, ILE75C, ILE90D, LEU0C, LEU102C, LEU123C, LEU123D, LEU29D, LEU37C, LEU52C, LEU62D, LEU6C, LYS-1C, LYS10C, LYS143D, LYS173C, LYS25D, LYS42C, MET116C, MET126D, MET19D, MET66D, MET7C, PHE117C, PHE125D, PHE152D, PHE78C, PRO104C, PRO119C, PRO129D, PRO18D, PRO21D, PRO23D, PRO28D, PRO88D, PRO98C, PRO98D, SER103C, SER124C, SER124D, SER146D, SER150D, SER166C, SER167C, SER171C, SER172C, SER17D, SER2C, SER45D, SER46D, SER64D, SER81C, SER94D, SER95D, THR130D, THR139D, THR24D, THR47D, THR76C, THR80C, THR87D, THR91D, THR96D, TRP147D, TRP86D, TYR-7C, TYR149D, TYR168C, TYR169C, TYR174C, TYR188D, TYR195D, TYR20D, TYR54C, TYR55C, TYR93D, VAL101C, VAL108C, VAL109C, VAL142D, VAL148D, VAL41C, VAL50D, VAL53C, VAL99C, VAL99D
• C-F: ALA4C, ALA4F, ARG8C, ARG8F, ASN5C, ASN5F, ASN70C, ASN70F, ASN74C, ASN74F, ASP-2C, ASP-2F, ASP-3C, ASP-3F, ASP-4C, ASP-4F, ASP-8C, ASP-8F, ASP12F, ASP68C, ASP68F, GLN3C, GLN3F, GLU71C, GLU71F, GLY73C, GLY73F, HIS1C, HIS1F, ILE75C, ILE75F, LEU0C, LEU0F, LYS-1C, LYS-1F, LYS-6C, LYS-6F, MET7C, MET7F, PRO69C, PRO69F, SER11C, SER2C, SER2F, TYR-7C, TYR-7F, TYR72C, TYR72F
• C-G: ALA4C, ALA4G, ARG16C, ARG16G, ARG8C, ARG8G, ASN15C, ASN15G, ASN5C, ASN5G, ASP12C, ASP12G, ASP68C, ASP68G, GLU71C, GLU71G, LEU13C, LEU13G, LEU6G, LEU9C, LEU9G, LYS10C, LYS10G, MET19C, MET19G, MET66C, MET66G, MET7C, MET7G, PHE14C, PHE14G, PRO18C, PRO18G, SER11C, SER11G, SER17C, SER17G, SER64C, SER64G, TYR72C, TYR72G
• C-H: PRO18C, PRO18H, SER17C, SER17H
• D-E: ALA107D, ALA120D, ALA141E, ALA170D, ALA43D, ALA4D, ALA92E, ARG122D, ARG16E, ARG207D, ARG79D, ARG8D, ARG97D, ARG97E, ASN48E, ASN5D, ASN63E, ASN74D, ASP-2D, ASP-3D, ASP-4D, ASP-5D, ASP-8D, ASP128E, ASP26E, ASP27E, ASP39D, ASP44E, ASP51D, ASP77D, ASP89E, CYS127E, CYS140E, GLN100D, GLN100E, GLN105D, GLN121D, GLN38D, GLN3D, GLU153E, GLU193E, GLU49E, GLU56D, GLY145E, GLY151E, GLY22E, GLY73D, HIS1D, ILE106D, ILE118D, ILE154E, ILE40D, ILE75D, ILE90E, LEU0D, LEU102D, LEU123D, LEU123E, LEU29E, LEU37D, LEU52D, LEU62E, LEU6D, LYS-1D, LYS10D, LYS143E, LYS173D, LYS25E, LYS42D, MET116D, MET126E, MET19E, MET66E, MET7D, PHE117D, PHE125E, PHE152E, PHE78D, PRO104D, PRO119D, PRO129E, PRO18E, PRO21E, PRO23E, PRO28E, PRO88E, PRO98D, PRO98E, SER103D, SER124D, SER124E, SER146E, SER150E, SER167D, SER171D, SER172D, SER17E, SER2D, SER45E, SER46E, SER64E, SER81D, SER94E, SER95E, THR130E, THR139E, THR24E, THR47E, THR76D, THR80D, THR87E, THR91E, THR96E, TRP147E, TRP86E, TYR-7D, TYR149E, TYR168D, TYR169D, TYR174D, TYR188E, TYR195E, TYR20E, TYR54D, TYR55D, TYR93E, VAL101D, VAL108D, VAL142E, VAL148E, VAL41D, VAL50E, VAL53D, VAL99D, VAL99E
• D-F: ALA4D, ALA4F, ARG16D, ARG16F, ARG8D, ARG8F, ASN15D, ASN15F, ASN5D, ASN5F, ASP12D, ASP12F, ASP68D, ASP68F, GLU71D, GLU71F, LEU13D, LEU13F, LEU9D, LEU9F, LYS10D, LYS10F, MET19D, MET19F, MET7D, MET7F, PHE14D, PHE14F, PRO18D, PRO18F, SER11D, SER11F, SER17D, SER17F, TYR72D, TYR72F
• D-G: PRO18D, PRO18G, SER17D, SER17G
• D-J: ALA4D, ALA4J, ARG8D, ARG8J, ASN5D, ASN5J, ASN70D, ASN70J, ASN74D, ASN74J, ASP-2D, ASP-2J, ASP-3D, ASP-3J, ASP-4D, ASP-4J, ASP-8D, ASP-8J, ASP12D, ASP12J, ASP68D, ASP68J, GLN3D, GLN3J, GLU71D, GLU71J, GLY73D, GLY73J, HIS1D, HIS1J, LEU0D, LEU0J, LYS-1D, LYS-1J, LYS-6D, LYS-6J, MET7D, MET7J, PRO69D, PRO69J, SER2D, SER2J, TYR-7D, TYR-7J, TYR72D, TYR72J
• E-F: PRO18E, PRO18F, SER17E, SER17F
• E-I: ALA4E, ALA4I, ARG8E, ARG8I, ASN5E, ASN5I, ASN70E, ASN70I, ASN74E, ASN74I, ASP-2E, ASP-2I, ASP-3E, ASP-3I, ASP-4E, ASP-4I, ASP-8E, ASP68E, ASP68I, GLN3E, GLN3I, GLU71E, GLU71I, GLY73E, GLY73I, HIS1E, HIS1I, LEU0E, LEU0I, LYS-1E, LYS-1I, LYS-6E, LYS-6I, PRO69E, PRO69I, SER2E, SER2I, TYR-7E, TYR-7I, TYR72E, TYR72I
• E-J: ALA4E, ALA4J, ARG16E, ARG16J, ARG8E, ARG8J, ASN15E, ASN15J, ASN5E, ASN5J, ASP12E, ASP12J, ASP68E, ASP68J, GLU71E, GLU71J, LEU13E, LEU13J, LEU9E, LEU9J, LYS10E, LYS10J, MET19E, MET19J, MET7E, MET7J, PHE14J, PRO18E, PRO18J, SER11E, SER11J, SER17E, SER17J, TYR72E, TYR72J
• F-G: ALA107F, ALA120F, ALA141G, ALA170F, ALA43F, ALA4F, ALA82F, ALA92G, ARG122F, ARG16G, ARG207F, ARG79F, ARG8F, ARG97F, ARG97G, ASN48G, ASN5F, ASN63G, ASN74F, ASP-2F, ASP-3F, ASP-4F, ASP-5F, ASP-8F, ASP128G, ASP26G, ASP27G, ASP39F, ASP44G, ASP51F, ASP77F, ASP89G, CYS127G, CYS140G, GLN100F, GLN100G, GLN105F, GLN121F, GLN38F, GLN3F, GLU153G, GLU193G, GLU49G, GLU56F, GLY145G, GLY151G, GLY22G, GLY73F, HIS1F, ILE106F, ILE118F, ILE154G, ILE40F, ILE75F, ILE90G, LEU0F, LEU102F, LEU123F, LEU123G, LEU29G, LEU37F, LEU52F, LEU62G, LEU6F, LYS-1F, LYS10F, LYS143G, LYS173F, LYS25G, LYS42F, MET116F, MET126G, MET19G, MET66G, MET7F, PHE117F, PHE125G, PHE152G, PHE78F, PRO104F, PRO119F, PRO129G, PRO18G, PRO21G, PRO23G, PRO28G, PRO88G, PRO98F, PRO98G, SER103F, SER124F, SER124G, SER146G, SER150G, SER167F, SER171F, SER172F, SER17G, SER2F, SER45G, SER46G, SER64G, SER81F, SER94G, SER95G, THR130G, THR139G, THR24G, THR47G, THR76F, THR80F, THR87G, THR91G, THR96G, TRP147G, TRP86G, TYR-7F, TYR149G, TYR168F, TYR169F, TYR174F, TYR195G, TYR20G, TYR54F, TYR55F, TYR93G, VAL101F, VAL108F, VAL142G, VAL148G, VAL41F, VAL53F, VAL99F, VAL99G
• F-J: ALA107J, ALA120J, ALA141F, ALA170J, ALA43J, ALA4J, ALA82J, ALA92F, ARG122J, ARG16F, ARG207J, ARG79J, ARG8J, ARG97F, ARG97J, ASN48F, ASN5J, ASN63F, ASN74J, ASP-2J, ASP-3J, ASP-4J, ASP-5J, ASP-8J, ASP128F, ASP26F, ASP27F, ASP39J, ASP44F, ASP51J, ASP77J, ASP89F, CYS127F, CYS140F, GLN100F, GLN100J, GLN105J, GLN121J, GLN38J, GLN3J, GLU153F, GLU193F, GLU49F, GLU56J, GLY145F, GLY151F, GLY22F, GLY73J, HIS1J, ILE106J, ILE118J, ILE154F, ILE40J, ILE75J, ILE90F, LEU0J, LEU102J, LEU123F, LEU123J, LEU29F, LEU37J, LEU52J, LEU62F, LEU6J, LYS-1J, LYS10J, LYS143F, LYS173J, LYS25F, LYS42J, LYS61F, MET116J, MET126F, MET19F, MET66F, MET7J, PHE117J, PHE125F, PHE152F, PHE78J, PRO104J, PRO119J, PRO129F, PRO18F, PRO21F, PRO23F, PRO28F, PRO88F, PRO98F, PRO98J, SER103J, SER124F, SER124J, SER146F, SER150F, SER166J, SER167J, SER171J, SER172J, SER17F, SER2J, SER45F, SER46F, SER64F, SER81J, SER94F, SER95F, THR130F, THR139F, THR24F, THR47F, THR76J, THR80J, THR87F, THR91F, THR96F, TRP147F, TRP86F, TYR-7J, TYR149F, TYR168J, TYR169J, TYR174J, TYR188F, TYR195F, TYR20F, TYR54J, TYR55J, TYR93F, VAL101J, VAL108J, VAL142F, VAL148F, VAL41J, VAL50F, VAL53J, VAL99F, VAL99J
• G-H: ALA107G, ALA120G, ALA141H, ALA170G, ALA43G, ALA4G, ALA82G, ALA92H, ARG122G, ARG16H, ARG207G, ARG79G, ARG8G, ARG97G, ARG97H, ASN48H, ASN5G, ASN63H, ASN74G, ASP-2G, ASP-3G, ASP-4G, ASP-5G, ASP-8G, ASP128H, ASP26H, ASP27H, ASP39G, ASP44H, ASP51G, ASP77G, ASP89H, CYS127H, CYS140H, CYS190H, CYS191H, GLN100G, GLN100H, GLN105G, GLN121G, GLN38G, GLN3G, GLU153H, GLU193H, GLU49H, GLU56G, GLY145H, GLY151H, GLY22H, GLY73G, HIS1G, ILE106G, ILE118G, ILE154H, ILE40G, ILE75G, ILE90H, LEU0G, LEU102G, LEU123G, LEU123H, LEU29H, LEU37G, LEU52G, LEU62H, LEU6G, LYS-1G, LYS10G, LYS143H, LYS173G, LYS25H, LYS42G, MET116G, MET126H, MET19H, MET66H, MET7G, PHE117G, PHE125H, PHE152H, PHE78G, PRO104G, PRO119G, PRO129H, PRO18H, PRO21H, PRO23H, PRO28H, PRO88H, PRO98G, PRO98H, SER103G, SER124G, SER124H, SER146H, SER150H, SER166G, SER167G, SER171G, SER172G, SER17H, SER2G, SER45H, SER46H, SER64H, SER81G, SER94H, SER95H, THR130H, THR139H, THR24H, THR47H, THR76G, THR80G, THR87H, THR91H, THR96H, TRP147H, TRP86H, TYR-7G, TYR149H, TYR168G, TYR169G, TYR174G, TYR188H, TYR195H, TYR20H, TYR54G, TYR55G, TYR93H, VAL101G, VAL108G, VAL109G, VAL142H, VAL148H, VAL41G, VAL53G, VAL99G, VAL99H
• H-I: ALA107H, ALA120H, ALA141I, ALA170H, ALA43H, ALA4H, ALA92I, ARG122H, ARG16I, ARG207H, ARG79H, ARG8H, ARG97H, ARG97I, ASN48I, ASN5H, ASN63I, ASN74H, ASP-2H, ASP-3H, ASP-4H, ASP-5H, ASP-8H, ASP128I, ASP26I, ASP27I, ASP39H, ASP44I, ASP51H, ASP77H, ASP89I, CYS127I, CYS140I, GLN100H, GLN100I, GLN105H, GLN121H, GLN38H, GLN3H, GLU153I, GLU193I, GLU49I, GLU56H, GLY145I, GLY151I, GLY22I, GLY73H, HIS1H, ILE106H, ILE118H, ILE154I, ILE40H, ILE75H, ILE90I, LEU0H, LEU102H, LEU123H, LEU123I, LEU37H, LEU52H, LEU62I, LEU6H, LYS-1H, LYS10H, LYS143I, LYS173H, LYS25I, LYS42H, MET116H, MET126I, MET19I, MET66I, MET7H, PHE117H, PHE125I, PHE152I, PHE78H, PRO104H, PRO119H, PRO129I, PRO18I, PRO21I, PRO23I, PRO28I, PRO88I, PRO98H, PRO98I, SER103H, SER124H, SER124I, SER146I, SER150I, SER166H, SER167H, SER171H, SER172H, SER17I, SER2H, SER45I, SER46I, SER64I, SER81H, SER94I, SER95I, THR130I, THR139I, THR24I, THR47I, THR76H, THR80H, THR87I, THR91I, THR96I, TRP147I, TRP86I, TYR-7H, TYR149I, TYR168H, TYR169H, TYR174H, TYR188I, TYR195I, TYR20I, TYR54H, TYR55H, TYR93I, VAL101H, VAL108H, VAL142I, VAL148I, VAL41H, VAL53H, VAL99H, VAL99I
• I-J: ALA107I, ALA120I, ALA141J, ALA170I, ALA43I, ALA4I, ALA82I, ALA92J, ARG122I, ARG16J, ARG207I, ARG79I, ARG8I, ARG97I, ARG97J, ASN48J, ASN5I, ASN63J, ASN74I, ASP-2I, ASP-3I, ASP-4I, ASP-5I, ASP-8I, ASP128J, ASP26J, ASP27J, ASP39I, ASP44J, ASP51I, ASP77I, ASP89J, CYS127J, CYS140J, CYS190J, CYS191J, GLN100I, GLN100J, GLN105I, GLN121I, GLN38I, GLN3I, GLU153J, GLU193J, GLU49J, GLU56I, GLY145J, GLY151J, GLY22J, GLY73I, HIS1I, ILE106I, ILE118I, ILE154J, ILE40I, ILE75I, ILE90J, LEU0I, LEU102I, LEU123I, LEU123J, LEU37I, LEU52I, LEU62J, LEU6I, LYS-1I, LYS10I, LYS143J, LYS173I, LYS25J, LYS42I, MET116I, MET126J, MET19J, MET66J, MET7I, PHE117I, PHE125J, PHE152J, PHE78I, PRO104I, PRO119I, PRO129J, PRO18J, PRO21J, PRO23J, PRO28J, PRO88J, PRO98I, PRO98J, SER103I, SER124I, SER124J, SER146J, SER150J, SER166I, SER167I, SER171I, SER172I, SER17J, SER2I, SER45J, SER46J, SER64J, SER81I, SER94J, SER95J, THR130J, THR139J, THR24J, THR36I, THR47J, THR76I, THR80I, THR87J, THR91J, THR96J, TRP147J, TRP86J, TYR-7I, TYR149J, TYR168I, TYR169I, TYR174I, TYR188J, TYR195J, TYR20J, TYR54I, TYR55I, TYR93J, VAL101I, VAL108I, VAL109I, VAL142J, VAL148J, VAL41I, VAL50J, VAL53I, VAL99I, VAL99J