3GQQ

crystal structure of the human retinal protein 4 (unc-119 homolog a). northeast structural genomics consortium target hr3066a

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 81
  • Norm. En. per Res.: -2.8206
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	35.9663	-72.0752	-36.1089	38	3	1	3489	2	9	15
A-C	-17.4887	-9.067	-64.9212	-91.4769	37	2	0	2929	0	18	14
A-D	-27.1729	-32.3981	-168.901	-228.472	81	8	1	6602	6	35	39
A-F	0.0	0.0	-3.592	-3.592	14	0	0	217	0	8	4
B-F	0.0	-0.9072	-15.3989	-16.3061	13	0	0	618	0	5	5
C-D	0.0	36.9914	-84.5553	-47.5639	40	7	1	3739	2	8	15
C-E	-5.4715	-13.3069	-131.851	-150.6294	63	5	1	4982	1	19	24
C-F	-28.08	-24.4171	-115.886	-168.3832	61	1	3	5083	2	19	21
D-E	-20.7249	-9.7327	-61.6091	-92.0667	34	1	0	2610	0	15	13

Interface residues

• A-B: ALA136A, ALA136B, ARG139A, ARG139B, ARG209A, ARG209B, GLU201A, GLU201B, GLU202A, GLU202B, GLU206A, GLU206B, GLY238B, HIS210A, HIS210B, ILE204A, ILE204B, ILE208A, ILE208B, LEU138A, LEU138B, PHE133A, PHE133B, PHE137A, PHE137B, PRO135A, PRO135B, PRO211A, PRO211B, SER205A, SER205B, SER237A, SER237B, THR134A, THR134B, THR239B, TYR236A, TYR236B
• A-C: ARG141C, ARG164A, ARG90C, ARG94C, ASP176A, ASP195A, ASP95C, ASP97C, GLN142C, GLN170A, GLN69A, GLU104C, GLU191C, GLY67A, GLY99C, HIS165A, ILE162A, LEU171A, LEU172A, LEU199A, LEU203A, LEU66A, LEU68A, LYS106C, LYS173A, LYS92C, PHE175A, PHE196A, PRO197A, PRO198A, SER174A, SER200A, SER98C, THR100C, TYR166A, VAL101C, VAL65A
• A-D: ALA145A, ALA232D, ARG118D, ARG119D, ARG127D, ARG130D, ARG160A, ARG168D, ARG209D, ARG70D, ARG90A, ARG94A, ASN117D, ASN157A, ASN158A, ASN169D, ASN188A, ASP120D, ASP122D, ASP153A, ASP176A, ASP217D, ASP223A, ASP224A, ASP233D, ASP74D, ASP95A, CYS182A, CYS190A, GLN132D, GLN215D, GLU104A, GLU148A, GLU191A, GLU213D, GLU63A, GLY180A, GLY73D, GLY99A, HIS178A, HIS192A, HIS210D, HIS229D, ILE116D, ILE183A, ILE71D, ILE93A, LEU114D, LEU121D, LYS106A, LYS154A, LYS187A, LYS231D, LYS92A, PHE128D, PHE149A, PHE159A, PHE177A, PHE179A, PHE181A, PRO115D, PRO123D, PRO155A, PRO184A, PRO211D, PRO62A, SER185A, SER186A, SER216D, SER235D, THR100A, THR146A, THR189A, THR72D, TYR212D, TYR75D, VAL101A, VAL129D, VAL147A, VAL156A, VAL89A
• A-F: ARG168A, ARG209A, ARG70A, ASN169A, GLN170A, GLN69A, GLU104F, GLU202A, GLU206A, GLY238F, ILE105F, LYS106F, THR134F, THR239F
• B-F: ARG139B, GLU201B, GLU202B, ILE105F, ILE204B, LEU199B, LEU203B, LYS106F, LYS107F, PRO108F, PRO197B, PRO198B, SER200B
• C-D: ALA136C, ALA136D, ARG139C, ARG139D, ARG209C, ARG209D, GLU201C, GLU201D, GLU202C, GLU202D, GLU206C, GLU206D, GLY238C, GLY238D, HIS210C, HIS210D, ILE204C, ILE204D, ILE208C, ILE208D, LEU138C, LEU138D, PHE133C, PHE133D, PHE137C, PHE137D, PRO135C, PRO135D, PRO211C, PRO211D, SER205C, SER205D, SER235D, SER237C, SER237D, THR134C, THR134D, THR239D, TYR236C, TYR236D
• C-E: ALA125C, ALA232C, ARG127C, ARG130C, ARG160E, ARG168C, ARG209C, ARG70C, ASN124C, ASN157E, ASN158E, ASN169C, ASN188E, ASP153E, ASP176E, ASP217C, ASP223E, ASP224E, ASP233C, ASP74C, CYS182E, CYS190E, GLN132C, GLN215C, GLU148E, GLU191E, GLU213C, GLU63E, GLY180E, GLY73C, HIS178E, HIS192E, HIS210C, HIS229C, ILE183E, ILE71C, LEU76C, LYS154E, LYS187E, LYS231C, PHE128C, PHE149E, PHE159E, PHE167C, PHE177E, PHE179E, PHE181E, PRO123C, PRO155E, PRO184E, PRO211C, PRO62E, SER185E, SER186E, SER235C, THR189E, THR214C, THR72C, TYR212C, TYR234C, TYR75C, VAL129C, VAL156E
• C-F: ALA145C, ALA232F, ARG127F, ARG130F, ARG160C, ARG168F, ARG209F, ARG70F, ASN157C, ASN158C, ASN169F, ASN188C, ASP153C, ASP176C, ASP195C, ASP233F, ASP74F, CYS182C, CYS190C, GLN132F, GLN142C, GLN215F, GLU148C, GLU191C, GLU213F, GLY126F, GLY180C, GLY238F, GLY73F, HIS178C, HIS192C, HIS210F, ILE183C, ILE193C, ILE71F, LYS173C, LYS187C, LYS231F, PHE128F, PHE149C, PHE159C, PHE177C, PHE179C, PHE181C, PRO155C, PRO184C, PRO211F, SER216F, SER235F, SER237F, THR146C, THR189C, THR214F, THR239F, THR72F, TYR212F, TYR234F, TYR75F, VAL129F, VAL147C, VAL156C
• D-E: ARG141D, ARG164E, ARG90D, ARG94D, ASP176E, ASP195E, ASP95D, ASP97D, GLN142D, GLN170E, GLN69E, GLU104D, GLY67E, GLY99D, HIS165E, ILE162E, LEU171E, LEU172E, LEU199E, LEU203E, LEU66E, LEU68E, LYS173E, LYS92D, PHE175E, PHE196E, PRO197E, PRO198E, SER174E, SER98D, THR100D, TYR166E, VAL101D, VAL65E