3GQL

crystal structure of activated receptor tyrosine kinase in complex with substrates

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 115
  • Norm. En. per Res.: -2.4218
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-52.174	17.4049	-243.74	-278.5091	115	10	1	11990	2	69	76
A-C	-13.1302	-11.9907	-93.2589	-118.3798	58	2	1	4511	0	30	27
B-C	0.0	0.0	-2.6033	-2.6033	9	0	0	153	0	7	7

Interface residues

• A-B: ALA615A, ALA615B, ALA645A, ALA645B, ALA671A, ALA671B, ARG470A, ARG470B, ARG622A, ARG622B, ARG646A, ARG646B, ARG675A, ARG675B, ASP468A, ASP468B, ASP524A, ASP524B, ASP527A, ASP527B, ASP554A, ASP554B, ASP674A, ASP674B, CYS619A, CYS619B, GLN553A, GLN553B, GLN680A, GLN680B, GLU464A, GLU464B, GLU467A, GLU467B, GLU472A, GLU472B, GLU522A, GLU522B, GLU531A, GLU531B, GLU533A, GLU533B, GLU670A, GLU670B, GLY539A, GLY539B, GLY555A, GLY555B, GLY643A, GLY643B, HIS679A, HIS679B, ILE529A, ILE529B, ILE538A, ILE538B, ILE620A, ILE620B, ILE676A, ILE676B, LEU465A, LEU465B, LEU525A, LEU525B, LEU528A, LEU557A, LEU614A, LEU614B, LEU644A, LYS523A, LYS523B, LYS536A, LYS536B, LYS540A, LYS540B, LYS617A, LYS617B, LYS618A, LYS618B, MET532A, MET532B, MET534A, MET534B, MET535A, MET535B, MET537A, MET537B, PHE642A, PRO466A, PRO466B, PRO469A, PRO469B, PRO741A, PRO741B, SER526A, SER526B, SER530A, SER530B, SER616A, SER616B, SER681A, SER681B, THR521A, THR521B, THR552A, THR552B, THR678A, THR678B, TRP471A, TRP471B, TYR463A, TYR463B, TYR613A, TYR677A, TYR677B
• A-C: ALA520C, ALA739A, ARG475C, ARG718A, ARG734A, ARG744A, ASP476C, ASP519C, ASP524C, ASP554C, ASP735A, CYS551C, CYS736A, GLN491C, GLN553C, GLN680A, GLN743A, GLN749A, GLU464C, GLU522C, GLU670A, GLU752A, GLY555C, GLY716A, HIS679A, HIS738A, ILE529C, ILE676A, LEU465C, LEU516C, LEU525C, LEU528C, LEU557C, LYS517C, LYS523C, LYS714A, LYS748A, MET515C, MET731A, PHE747A, PRO556C, PRO669A, PRO741A, PRO745A, SER518C, SER526C, SER681A, SER742A, THR521C, THR552C, THR678A, THR746A, TRP737A, TYR463C, TYR558C, TYR730A, VAL683A, VAL740A
• B-C: ARG470B, ASP468B, ASP503B, GLU464C, GLU467C, LYS502B, PRO466C, PRO469B, TYR463C