3GOD

structural basis for dnase activity of a conserved protein implicated in crispr-mediated antiviral defense

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 178
  • Norm. En. per Res.: -3.3922
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.8083	-76.6559	-75.8476	46	0	5	4281	0	9	17
A-C	-100.9482	-21.0906	-500.023	-622.0618	186	17	9	19212	1	30	15
A-D	-17.7391	-10.0651	-82.4242	-110.2285	47	4	0	2868	3	24	21
B-C	-8.7759	-8.9044	-72.0744	-89.7548	47	1	0	2593	3	20	17
B-D	-97.981	-17.4619	-488.362	-603.8048	178	24	9	18968	3	25	16

Interface residues

• A-B: ALA18A, ALA53A, ALA53B, ARG17A, ARG17B, ARG34A, ARG76A, ARG76B, ASN54A, ASN54B, ASP307A, ASP307B, ASP3A, ASP3B, GLN304A, GLN304B, GLU73A, GLU8A, GLU8B, GLY32A, GLY33A, HIS14A, HIS14B, ILE12A, ILE12B, ILE4A, ILE4B, ILE52A, LEU13A, LEU13B, LEU9A, LEU9B, LYS10A, LYS10B, LYS16A, LYS16B, PRO6A, PRO6B, SER15A, SER15B, SER5A, SER5B, SER7A, SER7B, THR11A, THR11B
• A-C: ALA237C, ALA238A, ALA238C, ALA251A, ALA251C, ALA69A, ALA69C, ALA70A, ALA70C, ALA75A, ALA75C, ALA77C, ALA94A, ALA94C, ARG111A, ARG118A, ARG118C, ARG129A, ARG129C, ARG258A, ARG258C, ARG259A, ARG259C, ARG27A, ARG27C, ARG293C, ARG72A, ARG72C, ARG76A, ARG76C, ASN230C, ASN54C, ASN95A, ASN95C, ASP125A, ASP98C, CYS26A, CYS26C, CYS84A, CYS84C, GLN107A, GLN117A, GLN117C, GLN24A, GLN24C, GLN68A, GLN68C, GLU100A, GLU100C, GLU109A, GLU114A, GLU114C, GLU73A, GLU73C, GLU8A, GLU96C, GLY121A, GLY121C, GLY235C, GLY245A, GLY245C, GLY249A, GLY249C, GLY255A, GLY255C, GLY260A, GLY260C, GLY261A, GLY261C, GLY61A, GLY61C, GLY63A, GLY63C, GLY78A, GLY78C, GLY82A, GLY82C, GLY85A, GLY85C, GLY86A, GLY86C, GLY87A, GLY87C, GLY88C, HIS248A, HIS248C, HIS254C, HIS25A, HIS25C, ILE246A, ILE246C, ILE66A, ILE66C, LEU104A, LEU116A, LEU116C, LEU23A, LEU23C, LEU244A, LEU250A, LEU250C, LEU262A, LEU262C, LEU29A, LEU29C, LEU59A, LEU59C, LEU60A, LEU60C, LEU74A, LEU74C, LEU80A, LEU80C, LEU91A, LEU91C, LYS10A, LYS256C, PHE122A, PHE124A, PHE124C, PHE264C, PHE83A, PHE83C, PHE92A, PHE92C, PRO106A, PRO112A, PRO247A, PRO247C, PRO6A, PRO90A, PRO90C, SER102A, SER108A, SER5A, SER65A, SER65C, SER7A, SER93A, SER93C, THR105A, THR113A, THR11A, THR239C, THR241A, THR241C, THR257C, THR62A, THR62C, THR64A, THR64C, THR67A, THR67C, THR89A, THR89C, TRP103A, TRP119A, TRP119C, TRP123A, TRP123C, TRP242A, TRP242C, TYR110A, TYR115A, TYR115C, TYR22A, TYR22C, TYR231A, TYR231C, TYR234C, VAL101A, VAL120A, VAL120C, VAL243A, VAL263A, VAL263C, VAL28A, VAL28C, VAL79A, VAL79C, VAL81A, VAL81C, VAL97A, VAL97C, VAL99A, VAL99C
• A-D: ALA213D, ALA222D, ALA283D, ARG206D, ARG215D, ARG224D, ARG285D, ARG293D, ARG34A, ARG43A, ASN223D, ASN31A, ASN49A, ASP220D, ASP287D, GLN290D, GLU209D, GLU288D, GLU289D, GLU36A, GLU41A, GLY208D, GLY216D, GLY218D, GLY219D, GLY286D, GLY32A, HIS228D, HIS44A, HIS46A, ILE50A, LEU281D, PHE225D, PRO221D, PRO51A, SER217D, SER282D, SER45A, THR205D, THR39A, TRP48A, TYR207D, TYR21A, TYR37A, TYR47A, VAL35A, VAL38A
• B-C: ALA18B, ALA213C, ALA222C, ALA283C, ARG206C, ARG215C, ARG224C, ARG285C, ARG34B, ARG43B, ASN19B, ASN223C, ASN31B, ASN49B, ASN54B, ASP220C, ASP227C, GLN290C, GLN294B, GLU209C, GLU288C, GLU289C, GLU36B, GLU41B, GLY208C, GLY216C, GLY218C, GLY219C, GLY286C, GLY32B, HIS228C, HIS44B, HIS46B, ILE50B, PHE225C, PRO221C, PRO51B, SER217C, SER45B, THR39B, TRP48B, TYR207C, TYR21B, TYR37B, TYR47B, VAL35B, VAL38B
• B-D: ALA237D, ALA238B, ALA238D, ALA251B, ALA251D, ALA69B, ALA69D, ALA70B, ALA70D, ALA75B, ALA75D, ALA77D, ALA94B, ALA94D, ARG111B, ARG118B, ARG118D, ARG129D, ARG215D, ARG258B, ARG258D, ARG259B, ARG259D, ARG27B, ARG27D, ARG293D, ARG72B, ARG72D, ARG76B, ARG76D, ASN54D, ASN95B, ASN95D, ASP98D, CYS26B, CYS26D, CYS84B, CYS84D, GLN107B, GLN117B, GLN117D, GLN24B, GLN24D, GLN68B, GLN68D, GLU109B, GLU114B, GLU114D, GLU73B, GLU73D, GLU8B, GLU96D, GLY121B, GLY121D, GLY235D, GLY245B, GLY245D, GLY249B, GLY249D, GLY255D, GLY260B, GLY260D, GLY261B, GLY261D, GLY61B, GLY61D, GLY63B, GLY63D, GLY78B, GLY78D, GLY82B, GLY82D, GLY85B, GLY85D, GLY86B, GLY86D, GLY87B, GLY87D, GLY88D, HIS248B, HIS248D, HIS254D, HIS25B, HIS25D, ILE246B, ILE246D, ILE66B, ILE66D, LEU104B, LEU116B, LEU116D, LEU23B, LEU23D, LEU244B, LEU250B, LEU250D, LEU262D, LEU29B, LEU29D, LEU59B, LEU59D, LEU60B, LEU60D, LEU74B, LEU74D, LEU80B, LEU80D, LEU91B, LEU91D, LEU9B, LYS10B, LYS256D, PHE122B, PHE124B, PHE124D, PHE264D, PHE83B, PHE83D, PHE92B, PHE92D, PRO106B, PRO112B, PRO247B, PRO247D, PRO6B, PRO90B, PRO90D, SER102B, SER108B, SER5B, SER65B, SER65D, SER7B, SER93B, SER93D, THR105B, THR113B, THR11B, THR239D, THR241B, THR241D, THR257D, THR62B, THR62D, THR64B, THR64D, THR67B, THR67D, THR89D, TRP103B, TRP119B, TRP119D, TRP123B, TRP123D, TRP242B, TRP242D, TYR110B, TYR115B, TYR115D, TYR22D, TYR231D, TYR234D, VAL101B, VAL120B, VAL120D, VAL243B, VAL263B, VAL263D, VAL28B, VAL28D, VAL79B, VAL79D, VAL81B, VAL81D, VAL97B, VAL97D, VAL99B, VAL99D