3GEF

crystal structure of the r482w mutant of lamin a/c

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 67
  • Norm. En. per Res.: -5.3496
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-167.448	35.6884	-226.665	-358.4247	67	31	6	8606	0	30	16
A-C	-24.3164	5.9785	-101.674	-120.0119	55	5	4	4634	0	21	27
A-D	-6.3257	40.1393	-16.7001	17.1135	39	0	0	811	5	21	23
B-C	-5.4762	21.6812	-14.6516	1.5534	29	0	0	779	3	12	19
B-D	-24.6031	-7.9047	-106.944	-139.4519	55	5	4	4651	2	23	28
C-D	-145.2128	4.0146	-216.281	-357.4791	71	19	6	7987	2	32	16

Interface residues

• A-B: ALA441A, ALA441B, ALA529A, ALA529B, ALA539A, ALA539B, ARG439A, ARG439B, ARG455B, ARG527A, ARG527B, ARG541A, ARG541B, ARG545A, ARG545B, ASN524A, ASN524B, ASP552A, ASP552B, GLU443A, GLU443B, GLU444A, GLU444B, GLU447A, GLU537A, GLU537B, GLU551A, GLU551B, GLY438A, GLY438B, LEU526A, LEU526B, LEU530A, LEU530B, LEU543A, LEU543B, LYS457A, LYS457B, LYS542A, LYS542B, MET540A, MET540B, SER525B, SER546A, SER546B, THR436A, THR436B, THR528A, THR528B, THR548A, THR548B, VAL440A, VAL440B, VAL442A, VAL442B, VAL445A, VAL445B, VAL538A, VAL538B, VAL544A, VAL544B, VAL547A, VAL547B, VAL549A, VAL549B, VAL550A, VAL550B
• A-C: ALA441A, ALA441C, ALA491A, ALA491C, ARG439A, ARG439C, ARG453A, ARG453C, ARG455A, ARG455C, ARG541A, ARG541C, ASN456A, ASN456C, ASN459A, ASN459C, ASP552A, ASP552C, GLN493A, GLN493C, GLU443A, GLU443C, GLU444A, GLU444C, GLU551A, GLU551C, GLY438A, GLY438C, GLY492A, GLY492C, LYS457A, LYS457C, LYS542A, LYS542C, SER458A, SER458C, SER525A, SER546A, SER546C, THR548A, THR548C, VAL442A, VAL442C, VAL445A, VAL445C, VAL494A, VAL494C, VAL544A, VAL544C, VAL547A, VAL547C, VAL549A, VAL549C, VAL550A, VAL550C
• A-D: ARG453A, ARG527A, ARG527D, ARG541A, ARG541D, ASP475A, ASP475D, ASP552A, ASP552D, GLU443A, GLU443D, GLU444A, GLU444D, GLU537A, GLU537D, GLU551A, GLU551D, LEU543A, LEU543D, LYS542A, LYS542D, MET540A, MET540D, SER525A, SER525D, THR548A, THR548D, VAL442A, VAL442D, VAL445A, VAL445D, VAL544A, VAL544D, VAL547A, VAL547D, VAL549A, VAL549D, VAL550A, VAL550D
• B-C: ARG453C, ARG541B, ARG541C, ASP552B, ASP552C, GLU443B, GLU443C, GLU444B, GLU444C, GLU551B, GLU551C, LYS457C, LYS542B, LYS542C, MET540B, MET540C, THR548B, THR548C, VAL442B, VAL442C, VAL445C, VAL544B, VAL544C, VAL547B, VAL547C, VAL549B, VAL549C, VAL550B, VAL550C
• B-D: ALA441B, ALA441D, ALA491B, ALA491D, ARG439B, ARG439D, ARG453B, ARG453D, ARG455B, ARG455D, ARG541B, ARG541D, ASN456B, ASN456D, ASN459B, ASN459D, ASP552B, ASP552D, GLN493B, GLN493D, GLU443B, GLU443D, GLU444B, GLU444D, GLU551B, GLU551D, GLY438D, GLY492B, GLY492D, LYS457B, LYS457D, LYS542D, SER458B, SER458D, SER525D, SER546B, SER546D, THR496B, THR548B, THR548D, TRP498B, VAL442B, VAL442D, VAL445B, VAL445D, VAL494B, VAL494D, VAL544B, VAL544D, VAL547B, VAL547D, VAL549B, VAL549D, VAL550B, VAL550D
• C-D: ALA441C, ALA441D, ALA529C, ALA529D, ALA539C, ALA539D, ARG439C, ARG439D, ARG455D, ARG527C, ARG527D, ARG541C, ARG541D, ARG545C, ARG545D, ASN524C, ASN524D, ASP552C, ASP552D, GLU443C, GLU443D, GLU444C, GLU444D, GLU447C, GLU447D, GLU537C, GLU537D, GLU551C, GLU551D, GLY438C, GLY438D, LEU526C, LEU526D, LEU530C, LEU530D, LEU543C, LEU543D, LYS457C, LYS457D, LYS542C, LYS542D, MET540C, MET540D, SER437C, SER437D, SER525C, SER525D, SER546C, SER546D, THR436C, THR436D, THR528C, THR528D, THR548C, THR548D, VAL440C, VAL440D, VAL442C, VAL442D, VAL445C, VAL445D, VAL538C, VAL538D, VAL544C, VAL544D, VAL547C, VAL547D, VAL549C, VAL549D, VAL550C, VAL550D