3G7V

islet amyloid polypeptide (iapp or amylin) fused to maltose binding protein

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 62
  • Norm. En. per Res.: -2.4794
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-2.8427	0.0	-150.881	-153.7237	62	3	4	5473	0	6	7
A-C	-7.1695	76.7321	-102.45	-32.8875	69	4	1	4287	1	45	43
C-D	-2.9459	0.0	-143.891	-146.8369	63	3	4	5446	0	6	7

Interface residues

• A-B: ALA375B, ALA378A, ALA378B, ALA383A, ALA383B, ALA395A, ALA395B, ARG381A, ARG381B, ARG98A, ARG98B, ASN173A, ASN173B, ASN384A, ASN384B, ASN391A, ASN391B, ASN392A, ASN392B, ASP95A, ASP95B, CYS377A, CYS377B, GLN380A, GLN380B, GLU172A, GLU172B, GLY101A, GLY174A, GLY174B, GLY394A, GLY394B, HIS388A, HIS388B, LEU382A, LEU382B, LEU386A, LEU386B, LYS170B, LYS175A, LYS175B, LYS83A, PHE385A, PHE385B, PHE393A, PHE393B, PHE92A, PHE92B, PRO91A, PRO91B, SER389A, SER389B, SER390A, SER390B, THR376A, THR376B, THR379A, THR379B, TYR171A, TYR171B, VAL387A, VAL387B
• A-C: ALA206A, ALA213A, ALA215A, ALA216A, ALA276C, ALA351A, ALA84C, ARG344A, ARG354A, ASN205A, ASN218A, ASN272C, ASN282C, ASN349A, ASP207A, ASP209A, ASP30C, ASP41A, ASP82C, GLN152A, GLN86C, GLU214A, GLU221A, GLU274C, GLU278C, GLU281C, GLU28C, GLU4C, GLY13A, GLY143A, GLY220A, GLY32C, GLY353A, GLY5C, HIS39A, ILE212A, ILE33C, ILE348A, LEU275C, LEU7C, LYS140A, LYS142A, LYS144A, LYS219A, LYS273C, LYS277C, LYS29C, LYS42A, LYS6C, LYS83C, LYS88C, MET148A, MET204A, PHE279C, PHE27C, PHE85C, PRO271C, PRO81C, SER145A, SER211A, SER270C, SER352A, THR208A, THR286C, THR31C, THR80C, TYR17A, TYR210A, TYR283C
• C-D: ALA375C, ALA378C, ALA378D, ALA383C, ALA383D, ALA395C, ALA395D, ARG381C, ARG381D, ARG98C, ARG98D, ASN173C, ASN173D, ASN384C, ASN384D, ASN391C, ASN391D, ASN392C, ASN392D, ASP95C, ASP95D, CYS377C, CYS377D, GLN380C, GLN380D, GLU172C, GLU172D, GLY101D, GLY174C, GLY174D, GLY394C, GLY394D, HIS388C, HIS388D, LEU382C, LEU382D, LEU386C, LEU386D, LYS170C, LYS170D, LYS175C, LYS175D, LYS83D, PHE385C, PHE385D, PHE393C, PHE393D, PHE92C, PHE92D, PRO91C, PRO91D, SER389C, SER389D, SER390C, SER390D, THR376C, THR376D, THR379C, THR379D, TYR171C, TYR171D, VAL387C, VAL387D