3G6A

crystal structure of anti-il-13 antibody cnto607

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: H-A
  • Int. Res.: 41
  • Norm. En. per Res.: -4.286
• Hub Node: H(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-31.2328	-12.8812	-441.233	-485.347	181	21	11	17895	0	14	22
H-A	-43.8353	-32.5099	-99.38	-175.7252	41	5	0	3158	4	12	1
H-B	-15.3563	-8.6356	-113.537	-137.529	59	4	0	4243	1	7	9
A-B	-15.2151	-17.9059	-420.35	-453.471	187	16	11	17442	2	14	22

Interface residues

• L-H: ALA128L, ALA131L, ALA134H, ALA145H, ALA146H, ALA174L, ALA175L, ALA177H, ALA40H, ALA42L, ALA61H, ALA97H, ARG38H, ARG98H, ASN170L, ASN35H, ASN95L, ASN96L, ASP106H, ASP110H, ASP139L, ASP153H, ASP49L, ASP50L, ASP52L, ASP62H, ASP84L, ASP91L, CYS135L, CYS149H, CYS87L, CYS96H, GLN108H, GLN114H, GLN127L, GLN168L, GLN180H, GLN36L, GLN37L, GLN39H, GLN41L, GLU124L, GLU125L, GLU161L, GLU221H, GLU46H, GLU6H, GLY100L, GLY101L, GLY113H, GLY115H, GLY148H, GLY159L, GLY183H, GLY40L, GLY42H, GLY44H, GLY50H, GLY56L, GLY88L, GLY99H, GLY99L, HIS104H, HIS173H, ILE137L, ILE34H, ILE47L, ILE57L, LEU100H, LEU118L, LEU126L, LEU133H, LEU133L, LEU136L, LEU147H, LEU150H, LEU179H, LEU179L, LEU181L, LEU184H, LEU187H, LEU45H, LEU45L, LEU4L, LEU59H, LYS126H, LYS130L, LYS138H, LYS152H, LYS167L, LYS172L, LYS205L, LYS218H, LYS219H, LYS43H, MET107H, MET92L, PHE119L, PHE131H, PHE140L, PHE175H, PHE31L, PHE98L, PRO109H, PRO120L, PRO121L, PRO132H, PRO135H, PRO165L, PRO176H, PRO39L, PRO41H, PRO43L, PRO54L, SER115L, SER122L, SER123L, SER129H, SER136H, SER137H, SER138L, SER139H, SER166L, SER169L, SER176L, SER177L, SER180L, SER181H, SER182H, SER186H, SER188H, SER189H, SER33L, SER49H, SER55L, THR117L, THR132L, THR162L, THR163L, THR164L, THR174H, THR192H, THR30L, THR58H, THR89L, THR94L, TRP105H, TRP112H, TRP33H, TRP34L, TRP36H, TRP47H, TRP90L, TYR111H, TYR173L, TYR178L, TYR185H, TYR35L, TYR48L, TYR60H, TYR85L, TYR86L, TYR95H, VAL116L, VAL130H, VAL134L, VAL151H, VAL160L, VAL178H, VAL190H, VAL191H, VAL207L, VAL220H, VAL32L, VAL37H, VAL44L, VAL46L, VAL48H, VAL93H, VAL93L, VAL97L
• H-A: ALA70A, ASN208H, ASN213H, ASN26A, ASN51A, ASN65A, ASN95A, ASP49A, ASP50A, ASP52A, ASP91A, GLY166H, GLY28A, GLY29A, GLY67A, HIS209H, ILE27A, LYS210H, LYS215H, MET92A, PHE31A, PRO211H, SER165H, SER212H, SER33A, SER64A, SER66A, THR125H, THR160H, THR214H, THR30A, THR89A, THR94A, TRP90A, TYR2A, TYR48A, VAL159H, VAL207H, VAL216H, VAL32A, VAL93A
• H-B: ALA102B, ALA23H, ARG19H, ARG72B, ASN213H, ASN30B, ASN74B, ASN77B, ASP106B, ASP54B, ASP73B, ASP73H, CYS22H, GLN108B, GLN13H, GLU157H, GLU6H, GLY101B, GLY10H, GLY8H, GLY9H, HIS104B, HIS209H, LEU100B, LEU117H, LEU11H, LEU18H, LEU20H, LYS210H, LYS76B, LYS76H, MET107B, PHE103B, PHE155H, PHE27B, PHE29B, PRO156H, PRO158H, PRO211H, SER17H, SER212H, SER21H, SER31B, SER55B, SER56B, SER75B, SER7H, THR116H, THR119H, THR125H, THR28B, THR78H, TRP105B, TYR32B, TYR53B, TYR80H, VAL118H, VAL12H, VAL5H
• A-B: ALA128A, ALA131A, ALA134B, ALA145B, ALA146B, ALA158A, ALA174A, ALA175A, ALA177B, ALA208A, ALA40B, ALA42A, ALA61B, ALA97B, ARG38B, ARG98B, ASN170A, ASN35B, ASN57B, ASN95A, ASN96A, ASP106B, ASP110B, ASP139A, ASP153B, ASP49A, ASP50A, ASP52A, ASP62B, ASP84A, ASP91A, CYS135A, CYS149B, CYS87A, CYS96B, GLN108B, GLN114B, GLN127A, GLN168A, GLN180B, GLN36A, GLN37A, GLN39B, GLN41A, GLN6A, GLU124A, GLU125A, GLU161A, GLU46B, GLU6B, GLY100A, GLY101A, GLY113B, GLY115B, GLY148B, GLY159A, GLY183B, GLY40A, GLY42B, GLY44B, GLY50B, GLY56A, GLY88A, GLY99A, GLY99B, HIS104B, HIS173B, ILE137A, ILE47A, ILE57A, LEU100B, LEU118A, LEU126A, LEU133A, LEU133B, LEU136A, LEU147B, LEU150B, LEU179A, LEU179B, LEU181A, LEU184B, LEU187B, LEU45A, LEU45B, LEU4B, LEU59B, LYS126B, LYS130A, LYS138B, LYS152B, LYS167A, LYS205A, LYS218B, LYS219B, LYS43B, LYS65B, MET107B, MET92A, PHE103B, PHE119A, PHE131B, PHE140A, PHE175B, PHE31A, PHE98A, PRO109B, PRO120A, PRO121A, PRO132B, PRO135B, PRO165A, PRO176B, PRO222B, PRO41B, PRO43A, PRO54A, SER115A, SER122A, SER123A, SER129B, SER136B, SER138A, SER139B, SER141B, SER166A, SER169A, SER176A, SER177A, SER180A, SER181B, SER182B, SER186B, SER188B, SER189B, SER33A, SER49B, SER55A, THR117A, THR132A, THR140B, THR162A, THR163A, THR164A, THR174B, THR192B, THR206A, THR30A, THR58B, THR89A, THR94A, TRP105B, TRP112B, TRP33B, TRP34A, TRP36B, TRP47B, TRP90A, TYR111B, TYR173A, TYR178A, TYR185B, TYR35A, TYR48A, TYR60B, TYR85A, TYR86A, TYR95B, VAL130B, VAL134A, VAL151B, VAL160A, VAL172B, VAL178B, VAL190B, VAL191B, VAL207A, VAL216B, VAL220B, VAL32A, VAL37B, VAL44A, VAL46A, VAL48B, VAL93A, VAL93B, VAL97A