3G33

crystal structure of cdk4/cyclin d3

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 126
  • Norm. En. per Res.: -3.2146
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-39.6616	-30.9489	-229.995	-300.6055	111	40	9	11859	3	30	35
B-C	-33.6224	-26.4309	-147.366	-207.4193	112	59	11	12782	2	33	37
B-D	-19.8677	-72.8891	-312.277	-405.0338	126	23	11	13574	8	77	60

Interface residues

• A-D: ALA110D, ALA138A, ALA153D, ALA154D, ALA63A, ALA70A, ALA84A, ARG10A, ARG114D, ARG135D, ARG138D, ARG26D, ARG33D, ARG37D, ARG60A, ARG66A, ARG67A, ARG78A, ARG87D, ARG90A, ASN139A, ASN46A, ASP134A, ASP139D, ASP151D, ASP159D, ASP81A, ASP89A, CYS125D, CYS83A, GLN296A, GLN29D, GLU115D, GLU122D, GLU141D, GLU35D, GLU61A, GLU69A, GLU72A, GLU74D, GLY146D, GLY47A, GLY48A, GLY49A, GLY50A, GLY51A, GLY52A, GLY53A, HIS32A, HIS73A, ILE121D, ILE156D, ILE169A, ILE56A, ILE92A, LEU108D, LEU109D, LEU113D, LEU119D, LEU137D, LEU143D, LEU145D, LEU148D, LEU152D, LEU31D, LEU34D, LEU54A, LEU64A, LEU65A, LEU68A, LEU79A, LEU96A, LYS112D, LYS123D, LYS147D, LYS149D, LYS93A, MET80A, PHE135A, PHE292A, PHE71A, PRO118D, PRO134D, PRO45A, PRO55A, SER111D, SER30D, SER57A, SER86A, THR116D, THR117D, THR120D, THR58A, THR85A, THR95A, TRP140D, TRP150D, TYR11A, TYR38D, TYR84D, VAL105D, VAL142D, VAL155D, VAL27D, VAL42A, VAL44A, VAL59A, VAL62A, VAL82A, VAL94A, VAL97A
• B-C: ALA110B, ALA138C, ALA153B, ALA154B, ALA63C, ALA70C, ALA84C, ARG114B, ARG135B, ARG138B, ARG26B, ARG33B, ARG37B, ARG60C, ARG66C, ARG67C, ARG78C, ARG87B, ASN139C, ASN46C, ASP134C, ASP139B, ASP151B, ASP159B, ASP81C, ASP89C, CYS125B, CYS83C, GLN296C, GLN29B, GLU115B, GLU122B, GLU141B, GLU35B, GLU36B, GLU61C, GLU69C, GLU72C, GLU74B, GLU91C, GLY146B, GLY47C, GLY48C, GLY49C, GLY50C, GLY51C, GLY52C, GLY53C, HIS32C, HIS73C, ILE121B, ILE156B, ILE169C, ILE56C, ILE92C, LEU108B, LEU109B, LEU113B, LEU119B, LEU137B, LEU143B, LEU145B, LEU148B, LEU152B, LEU31B, LEU34B, LEU54C, LEU64C, LEU65C, LEU68C, LEU79C, LEU96C, LYS112B, LYS123B, LYS147B, LYS149B, LYS93C, MET80C, PHE135C, PHE292C, PHE71C, PRO118B, PRO134B, PRO45C, PRO55C, SER111B, SER30B, SER57C, SER86C, THR116B, THR117B, THR120B, THR58C, THR85C, THR95C, TRP140B, TRP150B, TYR11C, TYR38B, TYR84B, VAL105B, VAL142B, VAL144B, VAL155B, VAL27B, VAL42C, VAL44C, VAL59C, VAL62C, VAL82C, VAL94C, VAL97C
• B-D: ALA176B, ALA176D, ALA182B, ALA182D, ALA187B, ALA187D, ALA190B, ALA190D, ALA211B, ALA211D, ALA249B, ALA250B, ALA250D, ALA61B, ALA61D, ARG172B, ARG172D, ARG174B, ARG174D, ARG252B, ARG252D, ARG72B, ARG72D, ASP173B, ASP173D, ASP192B, ASP192D, CYS189B, CYS189D, CYS68B, CYS68D, CYS73B, CYS73D, GLN175B, GLN175D, GLN183B, GLN183D, GLN213B, GLN213D, GLN71B, GLN71D, GLU115B, GLU115D, GLU248B, GLU248D, GLU253B, GLU253D, GLU66B, GLU66D, GLU69B, GLU69D, GLU70B, GLU70D, GLU74B, GLU74D, GLU75B, GLU75D, GLU76B, GLU76D, GLY214B, GLY214D, GLY216B, GLY216D, HIS158B, HIS158D, HIS181B, HIS181D, HIS55B, ILE247B, LEU170B, LEU170D, LEU177B, LEU177D, LEU186B, LEU186D, LEU188B, LEU188D, LEU215B, LEU215D, LEU251B, LEU251D, LEU60B, LEU65B, LEU65D, LYS123B, LYS123D, LYS179B, LYS179D, LYS180B, LYS180D, LYS58B, LYS58D, MET59B, MET59D, MET64B, MET64D, PHE185B, PHE185D, PHE78B, PHE78D, PRO171B, PRO171D, PRO79B, PRO79D, SER254B, SER254D, THR116B, THR116D, THR117B, THR117D, THR184B, THR184D, THR191B, THR191D, TRP63B, TRP63D, TYR62B, TYR62D, VAL178B, VAL178D, VAL212B, VAL212D, VAL67B, VAL67D, VAL77B, VAL77D