3FZJ

tsar low resolution crystal structure, tetragonal form

• Total interactions analyzed: 45
• Total true interactions: 18
• Strongest Interaction:
  • Chains: F-G
  • Int. Res.: 151
  • Norm. En. per Res.: -2.7145
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-57.2244	-72.633	-202.633	-332.4904	127	20	17	12607	8	55	37
A-D	-67.5033	-33.0834	-259.711	-360.2977	140	7	19	13434	4	24	26
A-I	0.0	0.0	66.6579	66.6579	14	10	0	551	0	0	3
B-C	-56.8325	-32.0579	-225.167	-314.0575	139	6	16	12161	3	26	25
B-E	0.0	0.0	-2.6381	-2.6381	10	0	0	261	0	1	2
B-I	-53.2743	4.2732	940.486	891.4848	57	151	0	6429	0	24	18
B-J	0.0	0.0	-2.8903	-2.8903	8	0	0	156	0	0	4
C-D	-21.4424	-64.7458	-248.758	-334.9462	125	72	21	15450	6	57	44
C-E	-8.7302	-28.4786	72.929	35.7202	75	51	0	5212	3	18	15
C-F	0.0	0.0	-0.6216	-0.6216	11	0	0	165	0	2	2
E-F	-13.6704	-58.5622	-250.315	-322.5476	130	32	19	14501	7	57	46
E-H	-31.817	-29.6037	-215.14	-276.5607	143	4	18	12106	3	27	30
E-I	0.0	0.0	16.0676	16.0676	14	14	0	427	0	0	3
E-J	-52.1516	7.6416	491.948	447.4381	55	145	0	6116	0	24	18
F-G	-65.9747	-30.7162	-313.193	-409.8839	151	14	24	14949	4	29	28
F-J	0.0	0.0	-0.2173	-0.2173	7	0	0	54	0	0	3
G-H	-33.4788	-66.5694	-209.245	-309.2932	120	51	15	13663	6	51	45
I-J	-8.0835	-61.1463	-191.147	-260.3769	126	32	17	14280	7	51	50

Interface residues

• A-B: ALA46A, ALA46B, ALA64A, ALA64B, ALA69A, ALA69B, ALA79A, ALA79B, ALA9A, ARG138B, ARG274B, ARG275A, ARG275B, ARG51B, ARG54B, ARG70A, ARG70B, ARG77A, ARG77B, ARG78A, ARG78B, ARG87A, ARG87B, ARG89A, ARG89B, ASP139B, ASP157A, ASP157B, ASP277A, ASP277B, GLN39B, GLN5A, GLN5B, GLN63A, GLN63B, GLN80A, GLN80B, GLN85A, GLN8A, GLN8B, GLU41A, GLU41B, GLU43A, GLU43B, GLU75A, GLU75B, GLU81A, GLU81B, GLU82A, GLU82B, GLU91A, GLU91B, GLY62A, GLY62B, GLY84A, GLY84B, GLY88A, GLY88B, HIS276A, HIS276B, HIS68A, HIS68B, ILE72A, ILE72B, ILE83A, ILE83B, LEU278A, LEU278B, LEU28A, LEU2A, LEU2B, LEU40A, LEU40B, LEU44A, LEU44B, LEU48A, LEU48B, LEU49B, LEU4A, LEU4B, LEU58B, LEU71A, LEU71B, LEU7A, LEU7B, LEU86A, LEU86B, LYS3A, LYS3B, LYS45A, LYS45B, LYS53B, LYS67A, LYS67B, MET1A, MET1B, MET66A, MET66B, PHE61A, PHE61B, PHE65A, PHE65B, PRO279A, PRO279B, PRO282A, PRO282B, PRO47A, PRO47B, SER57B, SER60A, SER60B, SER76A, SER76B, THR156A, THR281A, THR281B, THR52B, THR59B, THR6A, THR74A, THR74B, TRP90A, VAL280A, VAL280B, VAL50B, VAL73A, VAL73B
• A-D: ALA101A, ALA101D, ALA103A, ALA103D, ALA105A, ALA105D, ALA110A, ALA110D, ALA112A, ALA112D, ALA115A, ALA115D, ALA193A, ALA193D, ALA228A, ALA228D, ALA234A, ALA234D, ALA251A, ALA251D, ALA97A, ALA97D, ALA98A, ALA98D, ARG116A, ARG116D, ARG126A, ARG126D, ARG138A, ARG191A, ARG191D, ARG249A, ARG249D, ARG54D, ASN124A, ASN124D, ASN250A, ASN250D, ASP120D, ASP127A, ASP127D, ASP155A, ASP237A, ASP237D, ASP254A, CYS223A, CYS223D, GLN255A, GLN255D, GLU224A, GLU224D, GLU248A, GLU248D, GLY128A, GLY128D, GLY220A, GLY220D, GLY231A, GLY231D, HIS235A, HIS235D, HIS93A, HIS93D, ILE102A, ILE102D, ILE94A, ILE94D, LEU104A, LEU104D, LEU107A, LEU107D, LEU109A, LEU109D, LEU111A, LEU111D, LEU219A, LEU219D, LEU221A, LEU221D, LEU227A, LEU227D, LEU229A, LEU229D, LEU238A, LEU238D, LEU246A, LEU246D, LYS253A, LYS253D, PHE114A, PHE114D, PHE194A, PHE194D, PHE226A, PHE226D, PHE252A, PHE252D, PHE96A, PHE96D, PRO100A, PRO100D, PRO108A, PRO108D, PRO119A, PRO119D, PRO201A, PRO201D, PRO230A, PRO230D, PRO243A, PRO243D, SER113A, SER113D, SER196A, SER196D, SER225A, SER225D, SER236A, SER236D, SER99A, SER99D, THR122A, THR122D, THR156A, THR245A, THR245D, THR95A, THR95D, VAL121A, VAL121D, VAL123A, VAL123D, VAL125A, VAL125D, VAL222A, VAL222D, VAL232A, VAL232D, VAL233A, VAL233D
• A-I: ALA21I, ALA46A, ALA64A, ARG20I, GLN24I, GLN30I, GLN63A, GLY62A, PHE61A, PRO31I, PRO47A, SER18I, SER60A, THR59A
• B-C: ALA101B, ALA101C, ALA103B, ALA103C, ALA105B, ALA105C, ALA110B, ALA110C, ALA112B, ALA112C, ALA115B, ALA115C, ALA193B, ALA193C, ALA228B, ALA228C, ALA234B, ALA234C, ALA251B, ALA251C, ALA97B, ALA97C, ALA98B, ALA98C, ARG116B, ARG116C, ARG126B, ARG126C, ARG138C, ARG191B, ARG191C, ARG249B, ARG249C, ARG54B, ASN124B, ASN124C, ASN250B, ASN250C, ASP120B, ASP127B, ASP127C, ASP155C, ASP237B, ASP237C, CYS223B, CYS223C, GLN255B, GLN255C, GLU224B, GLU224C, GLU248B, GLU248C, GLY128B, GLY128C, GLY220B, GLY220C, GLY231B, GLY231C, HIS235B, HIS235C, HIS93B, HIS93C, ILE102B, ILE102C, ILE94B, ILE94C, LEU104B, LEU104C, LEU107B, LEU107C, LEU109B, LEU109C, LEU111B, LEU111C, LEU219B, LEU219C, LEU221B, LEU221C, LEU227B, LEU227C, LEU229B, LEU229C, LEU238B, LEU238C, LEU246B, LEU246C, LYS253B, LYS253C, PHE114B, PHE114C, PHE194B, PHE194C, PHE226B, PHE226C, PHE252B, PHE252C, PHE96B, PHE96C, PRO100B, PRO100C, PRO108B, PRO108C, PRO119B, PRO119C, PRO201B, PRO201C, PRO230B, PRO230C, PRO243B, PRO243C, SER113B, SER113C, SER196B, SER196C, SER225B, SER225C, SER236B, SER236C, SER99B, SER99C, THR122B, THR122C, THR156C, THR245B, THR245C, THR95B, THR95C, VAL121B, VAL121C, VAL123B, VAL123C, VAL125B, VAL125C, VAL222B, VAL222C, VAL232B, VAL232C, VAL233B, VAL233C
• B-E: ALA112B, ALA21E, ARG116B, ARG20E, GLN24E, GLN30E, HIS27E, LEU109B, LEU25E, VAL16E
• B-I: ALA115B, ALA21I, ALA283B, ALA285B, ALA35I, ALA46I, ARG116B, ARG20I, ARG289B, ARG51I, ARG54I, ARG87B, ARG89B, ASP120B, ASP42I, GLN30I, GLN38I, GLN85B, GLU117B, GLU41I, GLU81B, GLU82B, GLU91B, GLY17I, GLY286B, GLY55I, GLY84B, GLY88B, HIS293B, ILE37I, ILE83B, LEU19I, LEU296B, LEU48I, LEU49I, LEU86B, LYS45I, LYS53I, PHE114B, PHE118B, PHE61I, PRO119B, PRO282B, PRO31I, PRO47I, SER113B, SER18I, SER34I, SER57I, SER60I, THR52I, THR59I, TRP290B, TRP90B, VAL121B, VAL50I, VAL56I
• B-J: ARG116B, ARG87J, HIS293B, HIS294B, LEU109B, LEU296B, SER113B, TRP290B
• C-D: ALA46C, ALA46D, ALA64C, ALA64D, ALA69C, ALA69D, ALA79C, ALA79D, ARG138D, ARG274D, ARG275C, ARG275D, ARG51D, ARG70C, ARG70D, ARG77C, ARG77D, ARG78C, ARG78D, ARG87C, ARG87D, ARG89C, ARG89D, ASP139D, ASP277C, ASP277D, GLN39D, GLN5C, GLN5D, GLN63C, GLN63D, GLN80C, GLN80D, GLN85C, GLN85D, GLN8C, GLN8D, GLU41C, GLU41D, GLU43C, GLU43D, GLU75C, GLU75D, GLU81C, GLU81D, GLU82C, GLU82D, GLU91C, GLU91D, GLY140D, GLY62C, GLY62D, GLY84C, GLY84D, GLY88C, GLY88D, HIS276C, HIS276D, HIS68C, HIS68D, ILE72C, ILE72D, ILE83C, ILE83D, LEU278C, LEU278D, LEU28C, LEU2C, LEU2D, LEU40C, LEU40D, LEU44C, LEU44D, LEU48C, LEU48D, LEU49D, LEU4C, LEU4D, LEU58D, LEU71C, LEU71D, LEU7C, LEU7D, LEU86C, LEU86D, LYS3C, LYS3D, LYS45C, LYS45D, LYS53D, LYS67C, LYS67D, MET1C, MET1D, MET66C, MET66D, PHE61C, PHE61D, PHE65C, PHE65D, PRO279C, PRO279D, PRO282C, PRO282D, PRO47C, PRO47D, SER57D, SER60C, SER60D, SER76C, SER76D, THR281C, THR281D, THR52D, THR59C, THR59D, THR6C, THR74C, THR74D, TRP90C, VAL280C, VAL280D, VAL50D, VAL73C, VAL73D
• C-E: ALA179C, ALA181C, ALA21E, ALA22E, ALA234C, ALA23E, ALA69E, ALA9E, ARG174C, ARG183C, ARG191C, ARG70E, ARG77E, ARG78E, ARG87E, ARG89E, ASN180C, ASP120E, ASP237C, ASP254C, ASP263C, CYS12E, CYS190C, CYS257C, GLN173C, GLN175C, GLN24E, GLN255C, GLN262C, GLN5E, GLN80E, GLN85E, GLN8E, GLU14E, GLU15E, GLU186C, GLU75E, GLU81E, GLU91E, GLY84E, GLY88E, GLY92E, HIS176C, HIS235C, HIS27E, ILE11E, ILE13E, ILE259C, ILE83E, LEU10E, LEU238C, LEU256C, LEU25E, LEU261C, LEU26E, LEU28E, LEU4E, LEU71E, LEU7E, LEU86E, MET66E, PHE252C, PRO177C, PRO260C, SER236C, SER258C, SER76E, THR182C, THR6E, THR74E, TRP90E, TYR212C, VAL16E, VAL233C, VAL73E
• C-F: ARG183C, ASN180C, GLN175C, GLN262C, GLU186C, LEU2F, LEU44F, LYS45F, MET1F, PRO177C, THR182C
• E-F: ALA46E, ALA46F, ALA64E, ALA64F, ALA69E, ALA69F, ALA79E, ALA79F, ALA9E, ARG138F, ARG274F, ARG275E, ARG275F, ARG51F, ARG54F, ARG70F, ARG77E, ARG77F, ARG78E, ARG78F, ARG87E, ARG87F, ARG89E, ARG89F, ASP139F, ASP157E, ASP277E, ASP277F, ASP42F, GLN39F, GLN5E, GLN5F, GLN63E, GLN63F, GLN80E, GLN80F, GLN85E, GLN85F, GLN8E, GLN8F, GLU41E, GLU41F, GLU43E, GLU43F, GLU75E, GLU75F, GLU81E, GLU81F, GLU82E, GLU82F, GLU91E, GLU91F, GLY55F, GLY62E, GLY62F, GLY84E, GLY84F, GLY88E, GLY88F, HIS276E, HIS276F, HIS68E, HIS68F, ILE72E, ILE72F, ILE83E, ILE83F, LEU278E, LEU278F, LEU28E, LEU2E, LEU2F, LEU40E, LEU40F, LEU44E, LEU44F, LEU48E, LEU48F, LEU49F, LEU4E, LEU4F, LEU58F, LEU71E, LEU71F, LEU7E, LEU7F, LEU86E, LEU86F, LYS3E, LYS3F, LYS45E, LYS45F, LYS53F, LYS67E, LYS67F, MET1E, MET1F, MET66E, MET66F, PHE61E, PHE61F, PHE65E, PHE65F, PRO279E, PRO279F, PRO282E, PRO282F, PRO47E, PRO47F, SER57F, SER60E, SER60F, SER76E, SER76F, THR156E, THR281E, THR281F, THR52F, THR59E, THR59F, THR6E, THR74E, THR74F, TRP90E, VAL280E, VAL280F, VAL50F, VAL56F, VAL73E, VAL73F
• E-H: ALA101E, ALA101H, ALA103E, ALA103H, ALA105E, ALA105H, ALA110E, ALA110H, ALA112E, ALA112H, ALA115E, ALA115H, ALA193E, ALA228E, ALA228H, ALA234E, ALA234H, ALA251E, ALA251H, ALA97E, ALA97H, ALA98E, ALA98H, ARG116E, ARG116H, ARG126E, ARG126H, ARG138E, ARG191E, ARG191H, ARG249E, ARG249H, ARG54H, ASN124E, ASN124H, ASN250E, ASN250H, ASP120H, ASP127E, ASP127H, ASP155E, ASP157E, ASP237E, ASP237H, CYS223E, CYS223H, GLN255E, GLN255H, GLU15H, GLU224E, GLU224H, GLU248E, GLU248H, GLY128E, GLY128H, GLY220E, GLY220H, GLY231E, GLY231H, HIS235E, HIS235H, HIS93E, HIS93H, ILE102E, ILE102H, ILE94E, ILE94H, LEU104E, LEU104H, LEU107E, LEU107H, LEU109E, LEU109H, LEU111E, LEU111H, LEU219E, LEU219H, LEU221E, LEU221H, LEU227E, LEU227H, LEU229E, LEU229H, LEU238E, LEU238H, LEU246E, LEU246H, LYS253E, LYS253H, LYS53H, PHE114E, PHE114H, PHE194E, PHE194H, PHE226E, PHE226H, PHE252E, PHE252H, PHE96E, PHE96H, PRO100E, PRO100H, PRO108E, PRO108H, PRO119E, PRO119H, PRO131E, PRO201E, PRO201H, PRO230E, PRO230H, PRO243E, PRO243H, SER113E, SER113H, SER196E, SER225E, SER225H, SER236E, SER236H, SER57H, SER99E, SER99H, THR122E, THR122H, THR156E, THR245E, THR245H, THR95E, THR95H, VAL121E, VAL121H, VAL123E, VAL123H, VAL125E, VAL125H, VAL16H, VAL222E, VAL222H, VAL232E, VAL232H, VAL233E, VAL233H
• E-I: ALA21E, ALA46I, ALA64I, ARG20E, GLN24E, GLN30E, GLY62I, LYS45I, LYS53E, PHE61I, PRO31E, PRO47I, SER60I, THR59I
• E-J: ALA115J, ALA21E, ALA283J, ALA35E, ALA46E, ARG116J, ARG20E, ARG289J, ARG51E, ARG54E, ARG87J, ARG89J, ASP120J, ASP42E, GLN30E, GLN38E, GLN85J, GLU117J, GLU41E, GLU81J, GLU82J, GLU91J, GLY17E, GLY286J, GLY55E, GLY84J, GLY88J, HIS293J, ILE37E, ILE83J, LEU19E, LEU48E, LEU49E, LEU86J, LYS45E, LYS53E, PHE114J, PHE118J, PHE61E, PRO119J, PRO282J, PRO31E, PRO47E, SER113J, SER18E, SER34E, SER57E, SER60E, THR52E, THR59E, TRP290J, TRP90J, VAL121J, VAL50E, VAL56E
• F-G: ALA101F, ALA101G, ALA103F, ALA103G, ALA105F, ALA105G, ALA106F, ALA106G, ALA110F, ALA110G, ALA112F, ALA112G, ALA115F, ALA115G, ALA193F, ALA193G, ALA228F, ALA228G, ALA234F, ALA234G, ALA251F, ALA251G, ALA97F, ALA97G, ALA98F, ALA98G, ARG116F, ARG116G, ARG126F, ARG126G, ARG138G, ARG191F, ARG191G, ARG249F, ARG249G, ARG54F, ASN124F, ASN124G, ASN250F, ASN250G, ASP120F, ASP120G, ASP127F, ASP127G, ASP155G, ASP157G, ASP237F, ASP237G, ASP254G, CYS223F, CYS223G, GLN255F, GLN255G, GLU15F, GLU224F, GLU224G, GLU248F, GLU248G, GLY128F, GLY128G, GLY220F, GLY220G, GLY231F, GLY231G, HIS235F, HIS235G, HIS294F, HIS294G, HIS93F, HIS93G, ILE102F, ILE102G, ILE94F, ILE94G, LEU104F, LEU104G, LEU107F, LEU107G, LEU109F, LEU109G, LEU111F, LEU111G, LEU219F, LEU219G, LEU221F, LEU221G, LEU227F, LEU227G, LEU229F, LEU229G, LEU238F, LEU238G, LEU246F, LEU246G, LEU287F, LYS253F, LYS253G, LYS53F, PHE114F, PHE114G, PHE118G, PHE194F, PHE194G, PHE226F, PHE226G, PHE252F, PHE252G, PHE96F, PHE96G, PRO100F, PRO100G, PRO108F, PRO108G, PRO119F, PRO119G, PRO131G, PRO201F, PRO201G, PRO230F, PRO230G, PRO243F, PRO243G, SER113F, SER113G, SER196F, SER196G, SER225F, SER225G, SER236F, SER236G, SER99F, SER99G, THR122F, THR122G, THR156G, THR245F, THR245G, THR95F, THR95G, VAL121F, VAL121G, VAL123F, VAL123G, VAL125F, VAL125G, VAL222F, VAL222G, VAL232F, VAL232G, VAL233F, VAL233G
• F-J: ARG116J, ARG87F, HIS293J, HIS294J, LEU109J, SER113J, TRP290J
• G-H: ALA46G, ALA46H, ALA64G, ALA64H, ALA69G, ALA69H, ALA79G, ALA79H, ALA9G, ARG138H, ARG274H, ARG275G, ARG275H, ARG51H, ARG70H, ARG77G, ARG77H, ARG78G, ARG78H, ARG87G, ARG87H, ARG89G, ARG89H, ASP139H, ASP277G, ASP277H, ASP42H, GLN39H, GLN5G, GLN5H, GLN63G, GLN63H, GLN80G, GLN80H, GLN85G, GLN8G, GLN8H, GLU41G, GLU41H, GLU43G, GLU43H, GLU75G, GLU75H, GLU81G, GLU82G, GLU82H, GLU91G, GLY62G, GLY62H, GLY84G, GLY84H, GLY88G, HIS276G, HIS276H, HIS68G, HIS68H, ILE72G, ILE72H, ILE83G, ILE83H, LEU10H, LEU278G, LEU278H, LEU28G, LEU2G, LEU2H, LEU40G, LEU40H, LEU44G, LEU44H, LEU48G, LEU48H, LEU49H, LEU4G, LEU4H, LEU71G, LEU71H, LEU7G, LEU7H, LEU86G, LEU86H, LYS3G, LYS3H, LYS45G, LYS45H, LYS53H, LYS67G, LYS67H, MET1G, MET1H, MET66G, MET66H, PHE61G, PHE61H, PHE65G, PHE65H, PRO279G, PRO279H, PRO282G, PRO282H, PRO47G, PRO47H, SER57H, SER60G, SER60H, SER76G, SER76H, THR281G, THR281H, THR52H, THR59H, THR6G, THR74G, THR74H, TRP90G, VAL280G, VAL280H, VAL50H, VAL73G, VAL73H
• I-J: ALA46I, ALA46J, ALA64I, ALA64J, ALA69I, ALA69J, ALA79I, ALA79J, ALA9I, ARG138J, ARG274J, ARG275I, ARG275J, ARG51J, ARG70J, ARG77I, ARG77J, ARG78I, ARG78J, ARG87I, ARG87J, ARG89I, ARG89J, ASP139J, ASP277I, ASP277J, ASP42I, ASP42J, GLN39I, GLN39J, GLN5I, GLN5J, GLN63J, GLN80I, GLN80J, GLN85I, GLN85J, GLN8I, GLN8J, GLU41I, GLU41J, GLU43I, GLU43J, GLU75I, GLU75J, GLU81I, GLU81J, GLU82I, GLU82J, GLU91I, GLU91J, GLY62I, GLY62J, GLY84I, GLY84J, GLY88I, GLY88J, HIS276I, HIS276J, HIS68I, HIS68J, ILE72I, ILE72J, ILE83I, ILE83J, LEU26I, LEU278I, LEU278J, LEU28I, LEU2I, LEU2J, LEU40I, LEU40J, LEU44I, LEU44J, LEU48I, LEU48J, LEU49J, LEU4I, LEU4J, LEU71I, LEU71J, LEU7I, LEU7J, LEU86I, LEU86J, LYS3I, LYS3J, LYS45I, LYS45J, LYS53J, LYS67I, LYS67J, MET1I, MET1J, MET66I, MET66J, PHE61I, PHE61J, PHE65I, PHE65J, PRO279I, PRO279J, PRO282I, PRO282J, PRO47I, PRO47J, SER60I, SER60J, SER76I, SER76J, THR281I, THR281J, THR52J, THR59I, THR59J, THR6I, THR6J, THR74I, THR74J, TRP90I, VAL280I, VAL280J, VAL50J, VAL73I, VAL73J