3FZ7

crystal structure of apo glutamate decarboxylase beta from escherichia coli

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 407
  • Norm. En. per Res.: -5.2472
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-97.7529	50.1617	-551.594	-599.1852	191	17	5	21576	9	66	80
A-C	0.0	1.1198	-3.7062	-2.5864	32	0	0	416	0	15	12
A-E	0.0	7.7405	-3.6782	4.0623	31	0	0	447	0	15	12
A-F	-289.7768	-179.8098	-1644.99	-2114.5765	413	49	32	61391	33	146	113
B-C	-329.0916	-178.7127	-1627.81	-2135.6143	407	62	33	61436	33	146	114
B-D	0.0	8.0344	-4.3208	3.7136	36	0	0	450	0	15	13
B-F	0.0	7.6523	-4.7779	2.8744	35	0	0	472	0	17	13
C-D	-114.6668	54.8772	-665.858	-725.6475	219	24	8	25456	11	74	88
C-E	0.0	8.2244	-2.5996	5.6248	32	0	0	400	0	13	11
D-E	-298.8084	-189.2522	-1620.96	-2109.0206	412	47	33	61065	30	140	114
D-F	0.0	6.6806	-4.1612	2.5194	33	0	0	408	0	14	12
E-F	-95.1719	51.6378	-533.024	-576.5581	195	19	5	21524	8	69	83

Interface residues

• A-B: ALA20A, ALA20B, ALA27A, ALA27B, ALA345A, ALA345B, ALA434B, ALA458A, ALA458B, ALA56A, ALA56B, ARG17A, ARG17B, ARG333A, ARG333B, ARG398A, ARG398B, ARG400A, ARG400B, ARG402A, ARG402B, ARG426A, ARG426B, ARG427A, ARG427B, ARG57A, ARG57B, ASN344A, ASN344B, ASN47A, ASN47B, ASN55A, ASN55B, ASP15A, ASP15B, ASP40A, ASP40B, ASP432A, ASP432B, ASP440A, ASP440B, ASP450A, ASP450B, ASP48A, ASP48B, ASP53A, ASP53B, ASP68A, ASP68B, ASP69A, ASP69B, CYS425A, CYS425B, GLN343A, GLN343B, GLN348A, GLN348B, GLN44A, GLN44B, GLN455A, GLN455B, GLN459A, GLN459B, GLN460A, GLN460B, GLN58A, GLN58B, GLU12B, GLU337A, GLU337B, GLU397A, GLU397B, GLU430A, GLU430B, GLU435A, GLU435B, GLU439A, GLU439B, GLU49A, GLU49B, GLU70A, GLU70B, GLY19A, GLY19B, GLY338A, GLY338B, GLY403A, GLY403B, GLY428A, GLY428B, GLY456A, GLY456B, GLY54A, GLY54B, HIS451A, HIS451B, HIS73A, HIS73B, ILE23A, ILE23B, ILE26A, ILE26B, ILE457A, ILE457B, ILE45A, ILE45B, ILE46A, ILE46B, LEU13A, LEU13B, LEU14A, LEU14B, LEU279A, LEU279B, LEU334A, LEU334B, LEU399A, LEU399B, LEU401A, LEU401B, LEU436A, LEU436B, LEU437B, LEU438B, LEU448A, LEU448B, LEU454A, LEU454B, LEU50A, LEU50B, LEU52A, LEU52B, LEU60B, LYS21A, LYS21B, LYS341A, LYS341B, LYS453A, LYS453B, MET431A, MET431B, PHE18A, PHE18B, PHE277A, PHE277B, PHE429A, PHE429B, PHE433A, PHE433B, PHE43A, PHE43B, PRO452A, PRO452B, SER16A, SER16B, SER22A, SER22B, SER24A, SER24B, SER29A, SER346A, SER346B, SER396A, SER396B, THR25A, THR25B, THR340A, THR340B, THR66A, THR66B, TRP404A, TRP404B, TRP67A, TRP67B, TYR339A, TYR339B, TYR347A, TYR347B, TYR352A, TYR352B, TYR393B, TYR447A, TYR447B, TYR51A, TYR51B, VAL342A, VAL342B, VAL349A, VAL349B, VAL41A, VAL41B
• A-C: ALA20A, ALA95C, ARG17A, ARG38A, ARG38C, ARG402A, ARG99C, ASN81C, ASP39C, ASP40A, ASP40C, ASP432A, GLN44A, GLN58A, GLN92C, GLU36C, GLU435A, GLU70A, GLU70C, GLY19A, GLY307C, GLY308C, LEU306C, LEU401A, LEU436A, LYS74C, PHE18A, PHE433A, PRO91C, TYR305C, TYR447A, TYR51A
• A-E: ALA20E, ALA95A, ARG17E, ARG38A, ARG38E, ARG402E, ARG99A, ASN81A, ASP39A, ASP40A, ASP40E, ASP432E, GLN44E, GLN58E, GLN92A, GLU36A, GLU70A, GLU70E, GLY19E, GLY307A, GLY308A, LEU306A, LEU401E, LEU436E, LYS74A, PHE18E, PHE433E, PRO91A, TYR305A, TYR447E, TYR51E
• A-F: ALA105A, ALA105F, ALA112A, ALA112F, ALA118A, ALA118F, ALA129A, ALA129F, ALA170A, ALA170F, ALA27A, ALA27F, ALA280A, ALA280F, ALA314A, ALA314F, ALA321A, ALA321F, ALA326A, ALA326F, ALA408A, ALA408F, ALA42A, ALA42F, ALA458A, ALA458F, ALA56A, ALA56F, ALA61A, ALA61F, ALA94A, ALA94F, ALA95A, ALA95F, ARG142A, ARG142F, ARG171A, ARG171F, ARG319A, ARG319F, ARG31A, ARG31F, ARG333A, ARG333F, ARG336A, ARG336F, ARG38A, ARG38F, ARG400A, ARG400F, ARG426A, ARG426F, ARG427A, ARG427F, ARG57A, ARG57F, ARG99A, ARG99F, ASN102A, ASN102F, ASN115A, ASN115F, ASN302A, ASN302F, ASN316A, ASN316F, ASN461A, ASN461F, ASN47A, ASN47F, ASN55A, ASN55F, ASN59A, ASN59F, ASN71A, ASN71F, ASN81A, ASN81F, ASN83A, ASN83F, ASP106A, ASP106F, ASP153A, ASP153F, ASP174A, ASP174F, ASP304A, ASP304F, ASP39A, ASP39F, ASP40A, ASP40F, ASP48A, ASP48F, ASP53A, ASP53F, ASP68A, ASP68F, ASP69A, ASP69F, ASP77A, ASP77F, ASP86A, ASP86F, ASP97A, ASP97F, CYS100A, CYS100F, CYS130A, CYS130F, CYS165A, CYS165F, CYS284A, CYS284F, CYS64A, CYS64F, GLN117A, GLN117F, GLN163A, GLN163F, GLN297A, GLN297F, GLN309A, GLN309F, GLN323A, GLN323F, GLN327A, GLN327F, GLN405A, GLN405F, GLN44A, GLN44F, GLN459A, GLN459F, GLN460A, GLN460F, GLN58A, GLN58F, GLN65A, GLN65F, GLN92A, GLN92F, GLU128A, GLU128F, GLU28A, GLU28F, GLU298A, GLU298F, GLU330A, GLU330F, GLU337A, GLU337F, GLU36A, GLU36F, GLU397A, GLU397F, GLU49A, GLU49F, GLU70A, GLU70F, GLU88A, GLU88F, GLU89A, GLU89F, GLY116A, GLY116F, GLY125A, GLY125F, GLY278A, GLY278F, GLY283A, GLY283F, GLY307A, GLY307F, GLY308A, GLY308F, GLY322A, GLY322F, GLY335A, GLY335F, GLY338A, GLY338F, GLY403A, GLY403F, GLY54A, GLY54F, HIS109A, HIS109F, HIS167A, HIS167F, HIS275A, HIS275F, HIS35A, HIS35F, HIS465A, HIS465F, HIS73A, HIS73F, ILE124A, ILE124F, ILE164A, ILE164F, ILE23A, ILE23F, ILE26A, ILE26F, ILE310A, ILE310F, ILE315A, ILE315F, ILE325A, ILE325F, ILE45A, ILE45F, ILE46A, ILE46F, ILE80A, ILE80F, ILE85A, ILE85F, ILE96A, ILE96F, LEU107A, LEU107F, LEU132A, LEU132F, LEU177A, LEU177F, LEU279A, LEU279F, LEU282A, LEU282F, LEU295A, LEU299A, LEU299F, LEU306A, LEU306F, LEU332A, LEU332F, LEU334A, LEU334F, LEU34A, LEU34F, LEU50A, LEU50F, LEU52A, LEU52F, LEU60A, LEU60F, LEU75A, LEU75F, LEU78A, LEU78F, LEU98A, LEU98F, LYS114A, LYS138A, LYS138F, LYS168A, LYS168F, LYS276A, LYS276F, LYS30A, LYS30F, LYS341A, LYS341F, LYS464A, LYS464F, LYS74A, LYS74F, LYS82A, LYS82F, LYS87A, LYS87F, MET103A, MET103F, MET131A, MET131F, MET135A, MET135F, MET37A, MET37F, MET76A, MET76F, PHE169A, PHE169F, PHE249A, PHE249F, PHE253A, PHE253F, PHE301A, PHE301F, PHE313A, PHE313F, PHE317A, PHE317F, PHE32A, PHE32F, PHE331A, PHE331F, PHE409A, PHE409F, PHE43A, PHE43F, PHE463A, PHE463F, PHE63A, PHE63F, PRO113A, PRO113F, PRO252A, PRO252F, PRO281A, PRO281F, PRO296A, PRO296F, PRO320A, PRO320F, PRO33A, PRO33F, PRO407A, PRO407F, PRO91A, PRO91F, SER126A, SER126F, SER127A, SER127F, SER24A, SER24F, SER273A, SER273F, SER29A, SER29F, SER318A, SER318F, SER396A, SER396F, SER462A, SER462F, SER79A, SER79F, SER93A, SER93F, THR123A, THR123F, THR212A, THR212F, THR25A, THR25F, THR312A, THR312F, THR340A, THR340F, THR410A, THR410F, THR466A, THR466F, THR62A, THR62F, THR66A, THR66F, TRP108A, TRP108F, TRP139A, TRP139F, TRP166A, TRP166F, TRP173A, TRP173F, TRP404A, TRP404F, TRP67A, TRP67F, TRP84A, TRP84F, TYR172A, TYR172F, TYR213F, TYR305A, TYR305F, TYR328A, TYR328F, TYR329A, TYR329F, TYR339A, TYR339F, TYR393A, TYR393F, TYR51A, TYR51F, TYR90A, TYR90F, VAL101A, VAL101F, VAL104A, VAL104F, VAL175A, VAL175F, VAL300A, VAL300F, VAL303A, VAL303F, VAL324A, VAL324F, VAL342A, VAL342F, VAL406A, VAL406F, VAL41A, VAL41F, VAL72A, VAL72F
• B-C: ALA105B, ALA105C, ALA112B, ALA118B, ALA118C, ALA129B, ALA129C, ALA170B, ALA170C, ALA27B, ALA27C, ALA280B, ALA280C, ALA314B, ALA314C, ALA321B, ALA321C, ALA326B, ALA326C, ALA408B, ALA408C, ALA42B, ALA42C, ALA458B, ALA458C, ALA56B, ALA56C, ALA61B, ALA61C, ALA94B, ALA94C, ALA95B, ALA95C, ARG142B, ARG142C, ARG171B, ARG171C, ARG319B, ARG319C, ARG31B, ARG31C, ARG333B, ARG333C, ARG336B, ARG336C, ARG38B, ARG38C, ARG400B, ARG400C, ARG426B, ARG426C, ARG427C, ARG57B, ARG57C, ARG99B, ARG99C, ASN102B, ASN102C, ASN115B, ASN115C, ASN302B, ASN302C, ASN316B, ASN316C, ASN461B, ASN461C, ASN47B, ASN47C, ASN55B, ASN55C, ASN59B, ASN59C, ASN71B, ASN71C, ASN81B, ASN81C, ASN83B, ASN83C, ASP106B, ASP106C, ASP153B, ASP153C, ASP174B, ASP174C, ASP304B, ASP304C, ASP39B, ASP39C, ASP40B, ASP40C, ASP48B, ASP48C, ASP53B, ASP53C, ASP68B, ASP68C, ASP69B, ASP69C, ASP77B, ASP77C, ASP86B, ASP86C, ASP97B, CYS100B, CYS100C, CYS130B, CYS130C, CYS165B, CYS165C, CYS284B, CYS284C, CYS64B, CYS64C, GLN117B, GLN117C, GLN163B, GLN163C, GLN297B, GLN297C, GLN309B, GLN309C, GLN323B, GLN323C, GLN327B, GLN327C, GLN405B, GLN405C, GLN44B, GLN44C, GLN459B, GLN459C, GLN460B, GLN460C, GLN58B, GLN58C, GLN65B, GLN65C, GLN92B, GLN92C, GLU128B, GLU128C, GLU28B, GLU28C, GLU298B, GLU298C, GLU330B, GLU330C, GLU337B, GLU337C, GLU36B, GLU36C, GLU397B, GLU397C, GLU49B, GLU49C, GLU70B, GLU70C, GLU88B, GLU88C, GLU89B, GLU89C, GLY116B, GLY116C, GLY125B, GLY125C, GLY278B, GLY278C, GLY283B, GLY283C, GLY307B, GLY307C, GLY308B, GLY308C, GLY322B, GLY322C, GLY335B, GLY335C, GLY338B, GLY338C, GLY403B, GLY54B, GLY54C, HIS109B, HIS109C, HIS167B, HIS167C, HIS275B, HIS275C, HIS35B, HIS35C, HIS465B, HIS465C, HIS73B, HIS73C, ILE124B, ILE124C, ILE164B, ILE164C, ILE23B, ILE23C, ILE26B, ILE26C, ILE310B, ILE310C, ILE315B, ILE315C, ILE325B, ILE325C, ILE45B, ILE45C, ILE46B, ILE46C, ILE80B, ILE80C, ILE85B, ILE85C, ILE96B, ILE96C, LEU107B, LEU107C, LEU132B, LEU132C, LEU177C, LEU279B, LEU279C, LEU282B, LEU282C, LEU299B, LEU299C, LEU306B, LEU306C, LEU332B, LEU332C, LEU334B, LEU334C, LEU34B, LEU34C, LEU50B, LEU50C, LEU52B, LEU52C, LEU60B, LEU60C, LEU75B, LEU75C, LEU78B, LEU78C, LEU98B, LEU98C, LYS138B, LYS138C, LYS168B, LYS168C, LYS276B, LYS276C, LYS30B, LYS30C, LYS341B, LYS341C, LYS464B, LYS464C, LYS74B, LYS74C, LYS82B, LYS82C, LYS87B, LYS87C, MET103B, MET103C, MET131B, MET131C, MET135B, MET135C, MET37B, MET37C, MET76B, MET76C, PHE169B, PHE169C, PHE249B, PHE249C, PHE253B, PHE253C, PHE301B, PHE301C, PHE313B, PHE313C, PHE317B, PHE317C, PHE32B, PHE32C, PHE331B, PHE331C, PHE409B, PHE409C, PHE43B, PHE43C, PHE463B, PHE463C, PHE63B, PHE63C, PRO113B, PRO113C, PRO155B, PRO252B, PRO252C, PRO281B, PRO281C, PRO296B, PRO296C, PRO320B, PRO320C, PRO33B, PRO33C, PRO407B, PRO407C, PRO91B, PRO91C, SER126B, SER126C, SER127B, SER127C, SER24B, SER24C, SER273B, SER273C, SER29B, SER29C, SER318B, SER318C, SER396B, SER396C, SER462B, SER462C, SER79B, SER79C, SER93B, SER93C, THR123B, THR123C, THR212B, THR212C, THR25B, THR25C, THR312B, THR312C, THR340B, THR340C, THR410B, THR410C, THR466B, THR466C, THR62B, THR62C, THR66B, THR66C, TRP108B, TRP108C, TRP139B, TRP139C, TRP166B, TRP166C, TRP173B, TRP173C, TRP404B, TRP404C, TRP67B, TRP67C, TRP84B, TRP84C, TYR172B, TYR172C, TYR213B, TYR305B, TYR305C, TYR328B, TYR328C, TYR329B, TYR329C, TYR339B, TYR339C, TYR393B, TYR393C, TYR51B, TYR51C, TYR90B, TYR90C, VAL101B, VAL101C, VAL104B, VAL104C, VAL175B, VAL175C, VAL300B, VAL300C, VAL303B, VAL303C, VAL324B, VAL324C, VAL342B, VAL342C, VAL406B, VAL406C, VAL41B, VAL41C, VAL72B, VAL72C
• B-D: ALA20D, ALA443D, ALA95B, ARG17D, ARG38B, ARG38D, ARG402D, ARG99B, ASN81B, ASP39B, ASP40B, ASP40D, ASP432D, GLN44D, GLN58D, GLN92B, GLU36B, GLU70B, GLU70D, GLY19D, GLY307B, GLY308B, GLY403D, LEU306B, LEU401D, LEU436D, LYS74B, LYS74D, PHE18D, PHE433D, PRO91B, TRP404D, TYR305B, TYR328B, TYR447D, TYR51D
• B-F: ALA20B, ALA443B, ALA95F, ARG17B, ARG38B, ARG38F, ARG402B, ARG99F, ASN81F, ASP39F, ASP40B, ASP40F, ASP432B, GLN44B, GLN58B, GLN92F, GLU36F, GLU439B, GLU70B, GLU70F, GLY19B, GLY307F, GLY308F, LEU306F, LEU332F, LEU401B, LEU436B, LYS74F, PHE18B, PHE433B, PRO91F, TYR305F, TYR328F, TYR447B, TYR51B
• C-D: ALA20C, ALA20D, ALA251D, ALA255D, ALA27C, ALA27D, ALA345C, ALA345D, ALA434C, ALA434D, ALA458C, ALA458D, ALA56C, ALA56D, ARG10C, ARG17C, ARG17D, ARG333C, ARG333D, ARG336D, ARG370D, ARG398C, ARG398D, ARG400C, ARG400D, ARG402C, ARG402D, ARG426C, ARG426D, ARG427C, ARG427D, ARG57C, ARG57D, ASN344C, ASN344D, ASN47C, ASN47D, ASN55C, ASN55D, ASP15C, ASP15D, ASP257D, ASP372D, ASP394D, ASP40C, ASP40D, ASP432C, ASP432D, ASP440C, ASP440D, ASP450C, ASP450D, ASP48C, ASP48D, ASP53C, ASP53D, ASP68C, ASP68D, ASP69C, ASP69D, ASP8C, CYS425C, CYS425D, GLN221D, GLN343C, GLN343D, GLN348C, GLN348D, GLN44C, GLN44D, GLN455C, GLN455D, GLN459C, GLN459D, GLN460C, GLN460D, GLN58C, GLN58D, GLN5C, GLN65D, GLU12C, GLU337C, GLU337D, GLU373D, GLU397C, GLU397D, GLU430C, GLU430D, GLU435C, GLU435D, GLU439C, GLU439D, GLU49C, GLU49D, GLU70C, GLU70D, GLY19C, GLY19D, GLY338C, GLY338D, GLY374D, GLY403C, GLY403D, GLY428C, GLY428D, GLY456C, GLY456D, GLY54C, GLY54D, HIS451C, HIS451D, HIS73C, HIS73D, ILE23C, ILE23D, ILE258D, ILE26C, ILE26D, ILE457C, ILE457D, ILE45C, ILE45D, ILE46C, ILE46D, LEU13C, LEU13D, LEU14C, LEU14D, LEU279C, LEU279D, LEU334C, LEU334D, LEU399C, LEU399D, LEU401C, LEU401D, LEU436C, LEU436D, LEU437C, LEU437D, LEU448C, LEU448D, LEU454C, LEU454D, LEU50C, LEU50D, LEU52C, LEU52D, LEU9C, LYS21C, LYS21D, LYS341C, LYS341D, LYS453C, LYS453D, LYS4C, MET431C, MET431D, PHE18C, PHE18D, PHE219D, PHE253D, PHE277C, PHE277D, PHE429C, PHE429D, PHE433C, PHE433D, PHE43C, PHE43D, PRO252D, PRO256D, PRO371D, PRO452C, PRO452D, SER11C, SER16C, SER16D, SER22C, SER22D, SER24C, SER24D, SER346C, SER346D, SER396C, SER396D, THR25C, THR25D, THR340C, THR340D, THR66C, THR66D, THR7C, TRP404C, TRP404D, TRP67C, TRP67D, TYR217D, TYR339C, TYR339D, TYR347C, TYR347D, TYR352C, TYR352D, TYR393D, TYR447C, TYR447D, TYR51C, TYR51D, VAL254C, VAL254D, VAL259D, VAL342C, VAL342D, VAL349C, VAL349D, VAL41C, VAL41D, VAL6C
• C-E: ALA20C, ALA443C, ALA95E, ARG10C, ARG17C, ARG38C, ARG38E, ARG402C, ARG99E, ASN81E, ASP39E, ASP40C, ASP40E, ASP432C, GLN44C, GLN58C, GLN92E, GLU36E, GLU70C, GLY19C, GLY307E, GLY308E, LEU306E, LEU401C, LEU436C, LYS74E, PHE18C, PHE433C, PRO91E, TYR305E, TYR447C, TYR51C
• D-E: ALA105D, ALA105E, ALA112D, ALA118D, ALA118E, ALA129D, ALA129E, ALA170D, ALA170E, ALA27D, ALA27E, ALA280D, ALA280E, ALA314D, ALA314E, ALA321D, ALA321E, ALA326D, ALA326E, ALA408D, ALA408E, ALA42D, ALA42E, ALA458D, ALA458E, ALA56D, ALA56E, ALA61D, ALA61E, ALA94D, ALA94E, ALA95D, ALA95E, ARG142D, ARG142E, ARG171D, ARG171E, ARG319D, ARG319E, ARG31D, ARG31E, ARG333D, ARG333E, ARG336D, ARG336E, ARG38D, ARG38E, ARG400D, ARG400E, ARG426D, ARG426E, ARG57D, ARG57E, ARG99D, ARG99E, ASN102D, ASN102E, ASN115D, ASN115E, ASN302D, ASN302E, ASN316D, ASN316E, ASN461D, ASN461E, ASN47D, ASN47E, ASN55D, ASN55E, ASN59D, ASN59E, ASN71D, ASN71E, ASN81D, ASN81E, ASN83D, ASN83E, ASP106D, ASP106E, ASP153D, ASP153E, ASP174D, ASP174E, ASP304D, ASP304E, ASP39D, ASP39E, ASP40D, ASP40E, ASP48D, ASP48E, ASP53D, ASP53E, ASP68D, ASP68E, ASP69D, ASP69E, ASP77D, ASP77E, ASP86D, ASP86E, ASP97D, CYS100D, CYS100E, CYS130D, CYS130E, CYS165D, CYS165E, CYS284D, CYS284E, CYS64D, CYS64E, GLN117D, GLN117E, GLN163D, GLN163E, GLN297D, GLN297E, GLN309D, GLN309E, GLN323D, GLN323E, GLN327D, GLN327E, GLN405D, GLN405E, GLN44D, GLN44E, GLN459D, GLN459E, GLN460D, GLN460E, GLN58D, GLN58E, GLN65D, GLN65E, GLN92D, GLN92E, GLU128D, GLU128E, GLU28D, GLU28E, GLU298D, GLU298E, GLU330D, GLU330E, GLU337D, GLU337E, GLU36D, GLU36E, GLU397D, GLU397E, GLU49D, GLU49E, GLU70D, GLU70E, GLU88D, GLU88E, GLU89D, GLU89E, GLY116D, GLY116E, GLY125D, GLY125E, GLY278D, GLY278E, GLY283D, GLY283E, GLY307D, GLY307E, GLY308D, GLY308E, GLY311D, GLY311E, GLY322D, GLY322E, GLY335D, GLY335E, GLY338D, GLY338E, GLY403D, GLY403E, GLY54D, GLY54E, HIS109D, HIS109E, HIS167D, HIS167E, HIS275D, HIS275E, HIS35D, HIS35E, HIS465D, HIS465E, HIS73D, HIS73E, ILE124D, ILE124E, ILE164D, ILE164E, ILE23D, ILE23E, ILE26D, ILE26E, ILE310D, ILE310E, ILE315D, ILE315E, ILE325D, ILE325E, ILE45D, ILE45E, ILE46D, ILE46E, ILE80D, ILE80E, ILE85D, ILE85E, ILE96D, ILE96E, LEU107D, LEU107E, LEU132D, LEU132E, LEU177D, LEU177E, LEU279D, LEU279E, LEU282D, LEU282E, LEU295D, LEU295E, LEU299D, LEU299E, LEU306D, LEU306E, LEU332D, LEU332E, LEU334D, LEU334E, LEU34D, LEU34E, LEU50D, LEU50E, LEU52D, LEU52E, LEU60D, LEU60E, LEU75D, LEU75E, LEU78D, LEU78E, LEU98D, LEU98E, LYS114D, LYS138D, LYS138E, LYS168D, LYS168E, LYS276D, LYS276E, LYS30D, LYS30E, LYS341D, LYS341E, LYS464D, LYS464E, LYS74D, LYS74E, LYS82D, LYS82E, LYS87D, LYS87E, MET103D, MET103E, MET131D, MET131E, MET135D, MET135E, MET37D, MET37E, MET76D, MET76E, PHE169D, PHE169E, PHE249D, PHE249E, PHE253D, PHE253E, PHE301D, PHE301E, PHE313D, PHE313E, PHE317D, PHE317E, PHE32D, PHE32E, PHE331D, PHE331E, PHE409D, PHE409E, PHE43D, PHE43E, PHE463D, PHE463E, PHE63D, PHE63E, PRO113D, PRO113E, PRO252D, PRO252E, PRO281D, PRO281E, PRO296D, PRO320D, PRO320E, PRO33D, PRO33E, PRO407D, PRO407E, PRO91D, PRO91E, SER126D, SER126E, SER127D, SER127E, SER24D, SER24E, SER273D, SER273E, SER29D, SER29E, SER318D, SER318E, SER396D, SER396E, SER462D, SER462E, SER79D, SER79E, SER93D, SER93E, THR123D, THR123E, THR212D, THR212E, THR25D, THR25E, THR312D, THR312E, THR340D, THR340E, THR410D, THR410E, THR466D, THR466E, THR62D, THR62E, THR66D, THR66E, TRP108D, TRP108E, TRP139D, TRP139E, TRP166D, TRP166E, TRP173D, TRP173E, TRP404D, TRP404E, TRP67D, TRP67E, TRP84D, TRP84E, TYR172D, TYR172E, TYR213D, TYR213E, TYR305D, TYR305E, TYR328D, TYR328E, TYR329D, TYR329E, TYR339D, TYR339E, TYR393D, TYR393E, TYR51D, TYR51E, TYR90D, TYR90E, VAL101D, VAL101E, VAL104D, VAL104E, VAL175D, VAL175E, VAL300D, VAL300E, VAL303D, VAL303E, VAL324D, VAL324E, VAL342D, VAL342E, VAL406D, VAL406E, VAL41D, VAL41E, VAL72D, VAL72E
• D-F: ALA20F, ALA95D, ARG17F, ARG38D, ARG38F, ARG402F, ARG99D, ASN81D, ASP39D, ASP40D, ASP40F, ASP432F, GLN44F, GLN58F, GLN92D, GLU36D, GLU70D, GLU70F, GLY19F, GLY307D, GLY308D, GLY403F, LEU306D, LEU401F, LEU436F, LYS74D, PHE18F, PHE433F, PRO91D, TYR305D, TYR328D, TYR447F, TYR51F
• E-F: ALA20E, ALA20F, ALA27E, ALA27F, ALA345E, ALA345F, ALA434E, ALA434F, ALA458E, ALA458F, ALA56E, ALA56F, ARG10F, ARG17E, ARG17F, ARG333E, ARG333F, ARG398E, ARG398F, ARG400E, ARG400F, ARG402E, ARG402F, ARG426E, ARG426F, ARG427E, ARG427F, ARG57E, ARG57F, ASN344E, ASN344F, ASN47E, ASN47F, ASN55E, ASN55F, ASN71F, ASP15E, ASP15F, ASP40E, ASP40F, ASP432E, ASP432F, ASP440E, ASP440F, ASP450E, ASP450F, ASP48E, ASP48F, ASP53E, ASP53F, ASP68E, ASP68F, ASP69E, ASP69F, CYS425F, GLN343E, GLN343F, GLN348E, GLN348F, GLN44E, GLN44F, GLN455E, GLN455F, GLN459E, GLN459F, GLN460E, GLN460F, GLN58E, GLN58F, GLU12E, GLU12F, GLU28F, GLU337E, GLU337F, GLU397E, GLU397F, GLU430E, GLU430F, GLU435E, GLU435F, GLU439E, GLU439F, GLU49E, GLU49F, GLU70E, GLU70F, GLY19E, GLY19F, GLY338E, GLY338F, GLY403E, GLY403F, GLY428E, GLY428F, GLY456E, GLY456F, GLY54E, GLY54F, HIS451E, HIS451F, HIS73E, HIS73F, ILE23E, ILE23F, ILE26E, ILE26F, ILE457E, ILE457F, ILE45E, ILE45F, ILE46E, ILE46F, LEU13E, LEU13F, LEU14E, LEU14F, LEU279E, LEU279F, LEU334E, LEU334F, LEU399E, LEU399F, LEU401E, LEU401F, LEU436E, LEU436F, LEU437E, LEU437F, LEU448E, LEU448F, LEU454E, LEU454F, LEU50E, LEU50F, LEU52E, LEU52F, LYS21E, LYS21F, LYS341E, LYS341F, LYS453E, LYS453F, MET431E, MET431F, PHE18E, PHE18F, PHE277E, PHE277F, PHE429E, PHE429F, PHE433E, PHE433F, PHE43E, PHE43F, PRO452E, PRO452F, SER16E, SER16F, SER22E, SER22F, SER24E, SER24F, SER346E, SER346F, SER396E, SER396F, THR25E, THR25F, THR340E, THR340F, THR66E, THR66F, TRP404E, TRP404F, TRP67E, TRP67F, TYR339E, TYR339F, TYR347E, TYR347F, TYR352E, TYR352F, TYR393F, TYR447E, TYR447F, TYR51E, TYR51F, VAL254E, VAL254F, VAL342E, VAL342F, VAL349E, VAL349F, VAL41E, VAL41F