3FZ3

crystal structure of almond pru1 protein

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 234
  • Norm. En. per Res.: -4.621
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-132.4106	40.3201	-785.076	-877.1665	230	27	21	31626	1	48	44
A-C	-119.2147	29.8723	-779.11	-868.4524	232	28	24	30719	2	46	47
A-D	0.0	0.0	-2.6199	-2.6199	7	0	0	225	0	0	5
A-E	-15.0624	0.0	-72.6792	-87.7416	45	4	2	2736	0	0	5
A-F	-199.7901	2.0915	-812.185	-1009.8836	245	51	4	30502	10	142	128
B-C	-119.1926	18.7298	-788.75	-889.2128	233	25	23	30971	1	45	45
B-D	0.0	0.0	-78.3299	-78.3299	39	2	1	2817	0	0	4
B-E	-233.8141	25.9237	-846.999	-1054.8894	238	53	4	31389	10	141	122
B-F	0.0	0.0	-3.3608	-3.3608	10	0	0	261	0	0	5
C-D	-251.4621	9.7752	-839.617	-1081.304	234	44	4	31053	8	142	124
C-E	0.0	0.0	-1.6864	-1.6864	9	0	0	207	0	0	5
C-F	-4.3536	0.0	-75.0065	-79.3601	41	8	3	2876	0	0	4
D-E	-134.2037	16.98	-794.65	-911.8737	231	26	23	31154	2	46	47
D-F	-110.8397	18.9743	-781.258	-873.1234	232	31	22	31217	3	45	45
E-F	-128.788	38.3635	-794.53	-884.9544	230	39	22	31433	0	47	45

Interface residues

• A-B: ALA103A, ALA206A, ALA209A, ALA245A, ALA301A, ALA303A, ALA311A, ALA435B, ALA446B, ALA457B, ALA481B, ALA497B, ALA503B, ALA511B, ALA518B, ALA520B, ALA528B, ALA66B, ALA88A, ARG185A, ARG189A, ARG240A, ARG312A, ARG321A, ARG328A, ARG410A, ARG410B, ARG413A, ARG413B, ARG447B, ARG505B, ARG510B, ARG525B, ARG529B, ARG535B, ASN233A, ASN238A, ASN247A, ASN250A, ASN253A, ASN287A, ASN289A, ASN290A, ASN296A, ASN305A, ASN307A, ASN30B, ASN313A, ASN318A, ASN320A, ASN322A, ASN330A, ASN424B, ASN432B, ASN434B, ASN452B, ASN454B, ASN474B, ASN496B, ASN500B, ASN519B, ASN534B, ASN59A, ASN87A, ASP188A, ASP231A, ASP231B, ASP236A, ASP319A, ASP332A, ASP456B, ASP460B, ASP514B, CYS108A, CYS32B, CYS65B, GLN186A, GLN191A, GLN234A, GLN237A, GLN298A, GLN29B, GLN302A, GLN315A, GLN317A, GLN31A, GLN31B, GLN326A, GLN335A, GLN33B, GLN449B, GLN473B, GLN479B, GLN480B, GLN522B, GLN527B, GLN530B, GLN536B, GLN64A, GLN64B, GLU110A, GLU114A, GLU309A, GLU453B, GLU494B, GLU495B, GLU49A, GLU515B, GLU526B, GLU537B, GLY102A, GLY107A, GLY207A, GLY246A, GLY288A, GLY294A, GLY316A, GLY329A, GLY425B, GLY455B, GLY476B, GLY504B, GLY67B, HIS190A, HIS227B, HIS232A, HIS404B, HIS430B, HIS436B, HIS475B, HIS81A, ILE325A, ILE426B, ILE458B, ILE478B, ILE499B, ILE523B, ILE539B, LEU187A, LEU235A, LEU244A, LEU299A, LEU300A, LEU304A, LEU314A, LEU331A, LEU34B, LEU414B, LEU459B, LEU502B, LEU509B, LEU512B, LEU517B, LEU531B, LEU541B, LEU80A, LEU82A, LYS192A, LYS241A, LYS492B, LYS532B, PHE105A, PHE112A, PHE242A, PHE252A, PHE292A, PHE295A, PHE333A, PHE373A, PHE411A, PHE498B, PHE508B, PHE58A, PRO109A, PRO205A, PRO239A, PRO248A, PRO28A, PRO28B, PRO429B, PRO472B, PRO513B, PRO83A, PRO89A, SER106A, SER212A, SER229B, SER27A, SER27B, SER293A, SER428B, SER507B, SER524B, SER542B, SER543B, SER84A, SER86A, THR111A, THR193A, THR297A, THR310A, THR493B, THR501B, THR506B, THR538B, TRP211A, TRP431B, TYR210A, TYR213A, TYR243A, TYR427B, TYR521B, TYR533B, TYR85A, VAL100A, VAL104A, VAL208A, VAL228A, VAL291A, VAL306A, VAL327A, VAL334A, VAL433B, VAL448B, VAL450B, VAL451B, VAL471B, VAL477B, VAL516B, VAL68B
• A-C: ALA103C, ALA206C, ALA209C, ALA245C, ALA301C, ALA303C, ALA311C, ALA435A, ALA446A, ALA457A, ALA481A, ALA497A, ALA503A, ALA511A, ALA518A, ALA520A, ALA528A, ALA66A, ALA88C, ARG185C, ARG189C, ARG240C, ARG312C, ARG321C, ARG328C, ARG410A, ARG410C, ARG413A, ARG413C, ARG447A, ARG505A, ARG510A, ARG525A, ARG529A, ARG535A, ASN233C, ASN238C, ASN247C, ASN250C, ASN253C, ASN287C, ASN289C, ASN290C, ASN296C, ASN305C, ASN307C, ASN30A, ASN313C, ASN318C, ASN320C, ASN330C, ASN424A, ASN432A, ASN434A, ASN452A, ASN454A, ASN474A, ASN496A, ASN500A, ASN519A, ASN534A, ASN59C, ASN78C, ASN87C, ASP188C, ASP231A, ASP231C, ASP236C, ASP319C, ASP332C, ASP456A, ASP460A, ASP514A, CYS108C, CYS32A, CYS65A, GLN186C, GLN191C, GLN234C, GLN237C, GLN254C, GLN298C, GLN29A, GLN29C, GLN302C, GLN315C, GLN317C, GLN31A, GLN31C, GLN326C, GLN335C, GLN33A, GLN449A, GLN473A, GLN479A, GLN480A, GLN522A, GLN527A, GLN530A, GLN536A, GLN64A, GLN64C, GLU110C, GLU114C, GLU251C, GLU309C, GLU453A, GLU494A, GLU495A, GLU49C, GLU515A, GLU526A, GLU537A, GLY102C, GLY107C, GLY207C, GLY246C, GLY288C, GLY294C, GLY316C, GLY329C, GLY425A, GLY455A, GLY476A, GLY504A, GLY67A, HIS190C, HIS227A, HIS232C, HIS404A, HIS430A, HIS436A, HIS475A, HIS81C, ILE325C, ILE426A, ILE458A, ILE478A, ILE499A, ILE523A, ILE539A, LEU187C, LEU235C, LEU244C, LEU299C, LEU300C, LEU304C, LEU314C, LEU331C, LEU34A, LEU414A, LEU459A, LEU502A, LEU509A, LEU512A, LEU517A, LEU531A, LEU541A, LEU80C, LEU82C, LYS192C, LYS241C, LYS492A, LYS532A, PHE105C, PHE112C, PHE242C, PHE252C, PHE292C, PHE295C, PHE333C, PHE373C, PHE411C, PHE498A, PHE508A, PHE58C, PRO109C, PRO205C, PRO239C, PRO248C, PRO28A, PRO28C, PRO429A, PRO472A, PRO513A, PRO83C, PRO89C, SER106C, SER212C, SER229A, SER230A, SER27A, SER27C, SER293C, SER428A, SER507A, SER524A, SER542A, SER543A, SER84C, SER86C, THR111C, THR193C, THR297C, THR310C, THR493A, THR501A, THR506A, THR538A, TRP211C, TRP431A, TYR210C, TYR213C, TYR243C, TYR427A, TYR521A, TYR533A, TYR85C, VAL100C, VAL104C, VAL208C, VAL291C, VAL306C, VAL327C, VAL334C, VAL433A, VAL448A, VAL450A, VAL451A, VAL471A, VAL477A, VAL516A
• A-D: ALA511A, ARG505A, ARG505D, ARG510A, ARG510D, TYR533A, TYR533D
• A-E: ALA303A, ALA303E, ARG185A, ARG185E, ARG189A, ARG410A, ARG410E, ASN305A, ASN305E, CYS108A, CYS108E, CYS374A, CYS374E, GLN116A, GLN116E, GLN117A, GLN117E, GLN191A, GLN191E, GLN302A, GLN302E, GLU370A, GLU370E, GLU371A, GLU371E, GLY107A, GLY107E, GLY368A, GLY368E, LEU304A, LEU304E, LEU369A, LEU369E, LEU376A, PHE105A, PHE105E, PHE373A, PHE373E, PRO109A, PRO109E, SER106A, SER106E, SER375E, THR372A, THR372E
• A-F: ALA388A, ALA388F, ALA395A, ALA395F, ALA416A, ALA416F, ALA497A, ALA497F, ALA540A, ALA540F, ARG185A, ARG185F, ARG189A, ARG189F, ARG194A, ARG194F, ARG195A, ARG195F, ARG197A, ARG197F, ARG338F, ARG340F, ARG343F, ARG348F, ARG377A, ARG377F, ARG387A, ARG387F, ARG394A, ARG394F, ARG397A, ARG397F, ARG410A, ARG410F, ARG418A, ARG505A, ARG505F, ARG510F, ARG535A, ARG535F, ARG98A, ARG98F, ASN381A, ASN381F, ASN384A, ASN384F, ASN402A, ASN402F, ASN405A, ASN405F, ASN424A, ASN432A, ASN432F, ASN434A, ASN434F, ASN496A, ASN496F, ASN500A, ASN500F, ASN534A, ASN534F, ASP188A, ASP188F, ASP200A, ASP215F, ASP217A, ASP389A, ASP389F, CYS108A, CYS108F, CYS374A, CYS374F, GLN116A, GLN116F, GLN117A, GLN117F, GLN186F, GLN191A, GLN191F, GLN218A, GLN335A, GLN335F, GLN341F, GLN349F, GLN352F, GLN355F, GLN359F, GLN480A, GLN536A, GLN536F, GLN96A, GLU110A, GLU110F, GLU113A, GLU113F, GLU114A, GLU114F, GLU198A, GLU342F, GLU344F, GLU346F, GLU351F, GLU356F, GLU370A, GLU370F, GLU371A, GLU371F, GLU380A, GLU380F, GLU386A, GLU386F, GLU417A, GLU417F, GLU495A, GLU495F, GLU537A, GLU537F, GLY199A, GLY339F, GLY368A, GLY368F, GLY383A, GLY396A, GLY396F, GLY425A, GLY504A, GLY504F, GLY97A, GLY99A, GLY99F, HIS190A, HIS190F, HIS345F, HIS404A, HIS404F, HIS430A, HIS430F, ILE196A, ILE196F, ILE382F, ILE390A, ILE390F, ILE398A, ILE398F, ILE408A, ILE408F, ILE426A, ILE499A, ILE499F, ILE539A, ILE539F, ILE94A, LEU187A, LEU187F, LEU353F, LEU369A, LEU369F, LEU376A, LEU376F, LEU378A, LEU378F, LEU401A, LEU401F, LEU406A, LEU406F, LEU409A, LEU409F, LEU541A, LEU541F, LYS192A, LYS192F, LYS379A, LYS379F, LYS492A, LYS492F, PHE112A, PHE112F, PHE333A, PHE333F, PHE373A, PHE373F, PHE391A, PHE391F, PHE420A, PHE498A, PHE498F, PRO109A, PRO109F, PRO336A, PRO336F, PRO337A, PRO337F, PRO385A, PRO385F, PRO393A, PRO393F, PRO407A, PRO407F, SER115A, SER115F, SER375A, SER375F, SER392A, SER392F, SER399A, SER399F, SER403A, SER403F, SER415A, SER415F, SER507A, SER507F, SER542A, SER542F, SER543A, SER543F, THR111A, THR111F, THR193A, THR193F, THR372A, THR372F, THR400A, THR400F, THR501A, THR501F, THR506A, THR506F, THR538A, THR538F, TRP431A, TRP431F, TYR422A, TYR422F, TYR427A, TYR427F, TYR533A, TYR533F, TYR93A, VAL100F, VAL334A, VAL334F, VAL433A, VAL433F, VAL95A
• B-C: ALA103B, ALA206B, ALA209B, ALA245B, ALA301B, ALA303B, ALA311B, ALA435C, ALA446C, ALA457C, ALA481C, ALA497C, ALA503C, ALA511C, ALA518C, ALA520C, ALA528C, ALA66C, ALA88B, ARG185B, ARG189B, ARG240B, ARG312B, ARG321B, ARG328B, ARG410B, ARG410C, ARG413B, ARG413C, ARG447C, ARG505C, ARG510C, ARG525C, ARG529C, ARG535C, ASN233B, ASN238B, ASN247B, ASN250B, ASN253B, ASN287B, ASN289B, ASN290B, ASN296B, ASN305B, ASN307B, ASN30C, ASN313B, ASN318B, ASN320B, ASN330B, ASN424C, ASN432C, ASN434C, ASN452C, ASN454C, ASN474C, ASN496C, ASN500C, ASN519C, ASN534C, ASN59B, ASN87B, ASP188B, ASP231B, ASP231C, ASP236B, ASP319B, ASP332B, ASP456C, ASP460C, ASP514C, CYS108B, CYS32C, CYS65C, GLN186B, GLN191B, GLN234B, GLN237B, GLN254B, GLN298B, GLN29B, GLN29C, GLN302B, GLN315B, GLN317B, GLN31B, GLN31C, GLN326B, GLN335B, GLN33C, GLN449C, GLN473C, GLN479C, GLN480C, GLN522C, GLN527C, GLN530C, GLN536C, GLN64B, GLN64C, GLU110B, GLU113B, GLU114B, GLU309B, GLU453C, GLU494C, GLU495C, GLU49B, GLU515C, GLU526C, GLU537C, GLY102B, GLY107B, GLY207B, GLY246B, GLY288B, GLY294B, GLY316B, GLY329B, GLY425C, GLY455C, GLY476C, GLY504C, GLY67C, HIS190B, HIS227C, HIS232B, HIS404C, HIS430C, HIS436C, HIS475C, HIS81B, ILE325B, ILE426C, ILE458C, ILE478C, ILE499C, ILE523C, ILE539C, LEU187B, LEU235B, LEU244B, LEU299B, LEU300B, LEU304B, LEU314B, LEU331B, LEU34C, LEU414C, LEU459C, LEU502C, LEU509C, LEU512C, LEU517C, LEU531C, LEU541C, LEU80B, LEU82B, LYS192B, LYS241B, LYS492C, LYS532C, PHE105B, PHE112B, PHE242B, PHE252B, PHE292B, PHE295B, PHE333B, PHE373B, PHE411B, PHE498C, PHE508C, PHE58B, PRO109B, PRO205B, PRO239B, PRO248B, PRO28B, PRO28C, PRO429C, PRO472C, PRO513C, PRO83B, PRO89B, SER106B, SER212B, SER229C, SER230B, SER27B, SER27C, SER293B, SER428C, SER507C, SER524C, SER542C, SER543C, SER84B, SER86B, THR111B, THR193B, THR297B, THR310B, THR493C, THR501C, THR506C, THR538C, TRP211B, TRP431C, TYR210B, TYR213B, TYR243B, TYR427C, TYR521C, TYR533C, TYR85B, VAL100B, VAL104B, VAL208B, VAL228B, VAL291B, VAL306B, VAL327B, VAL334B, VAL433C, VAL448C, VAL450C, VAL451C, VAL471C, VAL477C, VAL516C, VAL68C
• B-D: ALA303B, ALA303D, ASN305B, ASN305D, CYS108B, CYS108D, CYS374B, CYS374D, GLN116B, GLN116D, GLN117B, GLN117D, GLN191B, GLN191D, GLN302B, GLN302D, GLU370B, GLU370D, GLU371B, GLU371D, GLY107B, GLY107D, GLY368B, GLY368D, LEU304B, LEU304D, LEU369B, LEU369D, PHE105B, PHE105D, PHE373B, PHE373D, PRO109B, PRO109D, SER106B, SER106D, SER375D, THR372B, THR372D
• B-E: ALA388B, ALA388E, ALA395B, ALA395E, ALA416B, ALA416E, ALA497B, ALA497E, ALA540B, ALA540E, ARG185B, ARG185E, ARG189B, ARG189E, ARG194B, ARG194E, ARG195B, ARG195E, ARG197B, ARG197E, ARG338B, ARG340B, ARG343B, ARG348B, ARG377B, ARG377E, ARG387B, ARG387E, ARG394B, ARG394E, ARG397B, ARG397E, ARG410B, ARG410E, ARG418E, ARG505B, ARG505E, ARG510B, ARG510E, ARG535B, ARG535E, ARG98B, ARG98E, ASN381B, ASN381E, ASN384B, ASN384E, ASN402B, ASN402E, ASN405B, ASN405E, ASN424E, ASN432B, ASN432E, ASN434B, ASN434E, ASN496B, ASN496E, ASN500B, ASN500E, ASN534B, ASN534E, ASP188B, ASP188E, ASP217E, ASP389B, ASP389E, CYS108B, CYS108E, CYS374B, CYS374E, GLN116B, GLN116E, GLN117B, GLN117E, GLN191B, GLN191E, GLN218E, GLN335B, GLN335E, GLN341B, GLN349B, GLN352B, GLN355B, GLN359B, GLN480E, GLN536B, GLN536E, GLN96E, GLU110B, GLU110E, GLU113B, GLU113E, GLU114B, GLU114E, GLU198E, GLU342B, GLU344B, GLU346B, GLU351B, GLU356B, GLU370B, GLU370E, GLU371B, GLU371E, GLU380B, GLU380E, GLU386B, GLU386E, GLU417B, GLU417E, GLU495B, GLU495E, GLU537B, GLU537E, GLY199E, GLY339B, GLY368B, GLY368E, GLY383E, GLY396B, GLY396E, GLY425E, GLY504B, GLY504E, GLY97E, HIS190B, HIS190E, HIS345B, HIS404B, HIS404E, HIS430B, HIS430E, ILE196E, ILE390B, ILE390E, ILE398B, ILE398E, ILE408B, ILE408E, ILE426E, ILE499B, ILE499E, ILE539B, ILE539E, LEU187B, LEU187E, LEU353B, LEU369B, LEU369E, LEU376B, LEU376E, LEU378B, LEU378E, LEU401B, LEU401E, LEU406B, LEU406E, LEU409B, LEU409E, LEU541B, LEU541E, LYS192B, LYS192E, LYS379B, LYS379E, LYS492B, LYS492E, PHE112B, PHE112E, PHE333B, PHE333E, PHE373B, PHE373E, PHE391B, PHE391E, PHE420B, PHE420E, PHE498B, PHE498E, PRO109B, PRO109E, PRO336B, PRO336E, PRO337B, PRO337E, PRO385B, PRO385E, PRO393B, PRO393E, PRO407B, PRO407E, SER115B, SER115E, SER375B, SER375E, SER392B, SER392E, SER399B, SER399E, SER403B, SER403E, SER415B, SER415E, SER507B, SER507E, SER542B, SER542E, SER543B, SER543E, THR111B, THR111E, THR193B, THR193E, THR372B, THR372E, THR400B, THR400E, THR501B, THR501E, THR506B, THR506E, THR538B, THR538E, TRP431B, TYR422B, TYR422E, TYR427B, TYR427E, TYR533B, TYR533E, VAL100B, VAL100E, VAL334B, VAL334E, VAL433B, VAL433E, VAL95E
• B-F: ARG505B, ARG505F, ARG510B, ARG510F, GLN536B, GLN536F, LYS532B, LYS532F, TYR533B, TYR533F
• C-D: ALA388C, ALA388D, ALA395C, ALA395D, ALA416C, ALA416D, ALA497C, ALA497D, ALA540C, ALA540D, ARG185C, ARG185D, ARG189C, ARG189D, ARG194C, ARG194D, ARG195C, ARG195D, ARG197C, ARG197D, ARG338C, ARG340C, ARG343C, ARG348C, ARG357C, ARG377C, ARG377D, ARG387C, ARG387D, ARG394C, ARG394D, ARG397C, ARG397D, ARG410C, ARG410D, ARG505C, ARG505D, ARG510C, ARG510D, ARG535C, ARG535D, ARG98C, ARG98D, ASN381C, ASN381D, ASN384C, ASN384D, ASN402C, ASN402D, ASN405C, ASN405D, ASN432C, ASN432D, ASN434C, ASN434D, ASN496C, ASN496D, ASN500C, ASN500D, ASN534C, ASN534D, ASP188C, ASP188D, ASP217D, ASP389C, ASP389D, CYS108C, CYS108D, CYS374C, CYS374D, GLN116C, GLN116D, GLN117C, GLN117D, GLN186C, GLN186D, GLN191C, GLN191D, GLN218D, GLN335C, GLN335D, GLN341C, GLN349C, GLN352C, GLN354C, GLN355C, GLN536C, GLN536D, GLU110C, GLU110D, GLU113C, GLU113D, GLU114C, GLU114D, GLU198D, GLU342C, GLU344C, GLU346C, GLU351C, GLU356C, GLU370C, GLU370D, GLU371C, GLU371D, GLU380C, GLU380D, GLU386C, GLU386D, GLU417C, GLU417D, GLU495C, GLU495D, GLU537C, GLU537D, GLY339C, GLY368C, GLY368D, GLY383D, GLY396C, GLY396D, GLY504C, GLY504D, GLY97D, HIS190C, HIS190D, HIS345C, HIS404C, HIS404D, HIS430C, HIS430D, ILE196D, ILE390C, ILE390D, ILE398C, ILE398D, ILE408C, ILE408D, ILE499C, ILE499D, ILE539C, ILE539D, LEU187C, LEU187D, LEU353C, LEU369C, LEU369D, LEU376C, LEU376D, LEU378C, LEU378D, LEU401C, LEU401D, LEU406C, LEU406D, LEU409C, LEU409D, LEU541C, LEU541D, LYS192C, LYS192D, LYS379C, LYS379D, LYS492C, LYS492D, PHE112C, PHE112D, PHE333C, PHE333D, PHE373C, PHE373D, PHE391C, PHE391D, PHE420C, PHE420D, PHE498C, PHE498D, PRO109C, PRO109D, PRO336C, PRO336D, PRO337C, PRO337D, PRO385C, PRO385D, PRO393C, PRO393D, PRO407C, PRO407D, SER115C, SER115D, SER375C, SER375D, SER392C, SER392D, SER399C, SER399D, SER403C, SER403D, SER415C, SER415D, SER507C, SER507D, SER542C, SER542D, SER543C, SER543D, THR111C, THR111D, THR193C, THR193D, THR372C, THR372D, THR400C, THR400D, THR501C, THR501D, THR506C, THR506D, THR538C, THR538D, TRP431C, TRP431D, TYR422C, TYR422D, TYR427C, TYR427D, TYR533C, TYR533D, VAL100C, VAL100D, VAL334C, VAL334D, VAL433C, VAL433D
• C-E: ARG410C, ARG410E, ARG505C, ARG505E, ARG510C, ARG510E, GLN536E, TYR533C, TYR533E
• C-F: ALA303C, ALA303F, ARG185C, ARG185F, ASN305C, ASN305F, CYS108C, CYS108F, CYS374C, CYS374F, GLN116C, GLN116F, GLN117C, GLN117F, GLN191C, GLN191F, GLN302C, GLN302F, GLU370C, GLU370F, GLU371C, GLU371F, GLY107C, GLY107F, GLY368C, GLY368F, LEU304C, LEU304F, LEU369C, LEU369F, PHE105C, PHE105F, PHE373C, PHE373F, PRO109C, PRO109F, SER106C, SER106F, SER375F, THR372C, THR372F
• D-E: ALA103D, ALA206D, ALA209D, ALA245D, ALA301D, ALA303D, ALA311D, ALA435E, ALA446E, ALA457E, ALA481E, ALA497E, ALA503E, ALA511E, ALA518E, ALA520E, ALA528E, ALA66E, ALA88D, ARG185D, ARG189D, ARG240D, ARG312D, ARG321D, ARG328D, ARG410D, ARG410E, ARG413D, ARG413E, ARG447E, ARG505E, ARG510E, ARG525E, ARG529E, ARG535E, ASN233D, ASN238D, ASN247D, ASN250D, ASN253D, ASN287D, ASN289D, ASN290D, ASN296D, ASN305D, ASN307D, ASN30E, ASN313D, ASN318D, ASN320D, ASN330D, ASN424E, ASN432E, ASN434E, ASN452E, ASN454E, ASN474E, ASN496E, ASN500E, ASN519E, ASN534E, ASN59D, ASN78D, ASN87D, ASP188D, ASP231D, ASP231E, ASP236D, ASP319D, ASP332D, ASP456E, ASP460E, ASP514E, CYS108D, CYS32E, CYS65E, GLN186D, GLN191D, GLN234D, GLN237D, GLN298D, GLN29E, GLN302D, GLN315D, GLN317D, GLN31D, GLN31E, GLN326D, GLN335D, GLN33E, GLN449E, GLN473E, GLN479E, GLN480E, GLN522E, GLN527E, GLN530E, GLN536E, GLN64D, GLN64E, GLU110D, GLU113D, GLU114D, GLU309D, GLU453E, GLU494E, GLU495E, GLU49D, GLU515E, GLU526E, GLU537E, GLY102D, GLY107D, GLY207D, GLY246D, GLY288D, GLY294D, GLY316D, GLY329D, GLY425E, GLY455E, GLY476E, GLY504E, GLY67E, HIS190D, HIS227E, HIS232D, HIS404E, HIS430E, HIS436E, HIS475E, HIS81D, ILE325D, ILE426E, ILE458E, ILE478E, ILE499E, ILE523E, ILE539E, LEU187D, LEU235D, LEU244D, LEU299D, LEU300D, LEU304D, LEU314D, LEU331D, LEU34E, LEU414E, LEU459E, LEU502E, LEU509E, LEU512E, LEU517E, LEU531E, LEU541E, LEU80D, LEU82D, LYS192D, LYS241D, LYS492E, LYS532E, PHE105D, PHE112D, PHE242D, PHE252D, PHE292D, PHE295D, PHE333D, PHE373D, PHE411D, PHE498E, PHE508E, PHE58D, PRO109D, PRO205D, PRO239D, PRO248D, PRO28D, PRO28E, PRO429E, PRO472E, PRO513E, PRO83D, PRO89D, SER106D, SER212D, SER229E, SER230E, SER27D, SER27E, SER293D, SER428E, SER507E, SER524E, SER542E, SER543E, SER84D, SER86D, THR111D, THR193D, THR297D, THR310D, THR493E, THR501E, THR506E, THR538E, TRP211D, TRP431E, TYR210D, TYR213D, TYR243D, TYR427E, TYR521E, TYR533E, TYR85D, VAL100D, VAL104D, VAL208D, VAL228D, VAL291D, VAL306D, VAL327D, VAL334D, VAL433E, VAL448E, VAL450E, VAL451E, VAL471E, VAL477E, VAL516E
• D-F: ALA103F, ALA206F, ALA209F, ALA245F, ALA301F, ALA303F, ALA311F, ALA435D, ALA446D, ALA457D, ALA481D, ALA497D, ALA503D, ALA511D, ALA518D, ALA520D, ALA528D, ALA66D, ALA88F, ARG185F, ARG189F, ARG240F, ARG312F, ARG321F, ARG328F, ARG410D, ARG410F, ARG413D, ARG413F, ARG447D, ARG505D, ARG510D, ARG525D, ARG529D, ARG535D, ASN233F, ASN238F, ASN247F, ASN250F, ASN253F, ASN287F, ASN289F, ASN290F, ASN296F, ASN305F, ASN307F, ASN30D, ASN313F, ASN318F, ASN320F, ASN330F, ASN424D, ASN432D, ASN434D, ASN452D, ASN454D, ASN474D, ASN496D, ASN500D, ASN519D, ASN534D, ASN59F, ASN78F, ASN87F, ASP188F, ASP231D, ASP231F, ASP236F, ASP319F, ASP332F, ASP456D, ASP460D, ASP514D, CYS108F, CYS32D, CYS65D, GLN186F, GLN191F, GLN234F, GLN237F, GLN298F, GLN29D, GLN29F, GLN302F, GLN315F, GLN317F, GLN31D, GLN31F, GLN326F, GLN33D, GLN449D, GLN473D, GLN479D, GLN480D, GLN522D, GLN527D, GLN530D, GLN536D, GLN64D, GLN64F, GLU110F, GLU114F, GLU249F, GLU309F, GLU453D, GLU494D, GLU495D, GLU49F, GLU515D, GLU526D, GLU537D, GLY102F, GLY107F, GLY207F, GLY246F, GLY288F, GLY294F, GLY316F, GLY329F, GLY425D, GLY455D, GLY476D, GLY504D, GLY67D, HIS190F, HIS227D, HIS232F, HIS404D, HIS430D, HIS436D, HIS475D, HIS81F, ILE325F, ILE426D, ILE458D, ILE478D, ILE499D, ILE523D, ILE539D, LEU187F, LEU235F, LEU244F, LEU299F, LEU300F, LEU304F, LEU314F, LEU331F, LEU34D, LEU414D, LEU459D, LEU502D, LEU509D, LEU512D, LEU517D, LEU531D, LEU541D, LEU80F, LEU82F, LYS192F, LYS241F, LYS492D, LYS532D, PHE105F, PHE112F, PHE242F, PHE252F, PHE292F, PHE295F, PHE333F, PHE373F, PHE411F, PHE498D, PHE508D, PHE58F, PRO109F, PRO205F, PRO239F, PRO248F, PRO28D, PRO28F, PRO429D, PRO472D, PRO513D, PRO83F, PRO89F, SER106F, SER212F, SER229D, SER230F, SER27D, SER27F, SER293F, SER428D, SER507D, SER524D, SER542D, SER543D, SER84F, SER86F, THR111F, THR193F, THR297F, THR310F, THR493D, THR501D, THR506D, THR538D, TRP211F, TRP431D, TYR210F, TYR213F, TYR243F, TYR427D, TYR521D, TYR533D, TYR85F, VAL100F, VAL104F, VAL208F, VAL228F, VAL291F, VAL306F, VAL327F, VAL334F, VAL433D, VAL448D, VAL450D, VAL451D, VAL471D, VAL477D, VAL516D, VAL68D
• E-F: ALA103E, ALA206E, ALA209E, ALA245E, ALA301E, ALA303E, ALA311E, ALA435F, ALA446F, ALA457F, ALA481F, ALA497F, ALA503F, ALA511F, ALA518F, ALA520F, ALA528F, ALA66F, ALA88E, ARG185E, ARG189E, ARG240E, ARG312E, ARG321E, ARG328E, ARG394F, ARG410E, ARG410F, ARG413F, ARG447F, ARG505F, ARG510F, ARG525F, ARG529F, ARG535F, ASN233E, ASN238E, ASN247E, ASN250E, ASN253E, ASN287E, ASN289E, ASN290E, ASN296E, ASN305E, ASN307E, ASN30F, ASN313E, ASN318E, ASN320E, ASN330E, ASN424F, ASN432F, ASN434F, ASN452F, ASN454F, ASN474F, ASN496F, ASN500F, ASN519F, ASN534F, ASN59E, ASN87E, ASP188E, ASP231E, ASP231F, ASP236E, ASP319E, ASP332E, ASP456F, ASP460F, ASP514F, CYS108E, CYS32F, CYS65F, GLN186E, GLN191E, GLN234E, GLN237E, GLN298E, GLN29E, GLN29F, GLN302E, GLN315E, GLN317E, GLN31E, GLN31F, GLN326E, GLN33F, GLN449F, GLN473F, GLN479F, GLN480F, GLN522F, GLN527F, GLN530F, GLN536F, GLN64E, GLN64F, GLU110E, GLU113E, GLU114E, GLU309E, GLU453F, GLU494F, GLU495F, GLU49E, GLU515F, GLU526F, GLU537F, GLY102E, GLY107E, GLY207E, GLY246E, GLY288E, GLY294E, GLY316E, GLY329E, GLY425F, GLY455F, GLY476F, GLY504F, GLY67F, HIS190E, HIS227F, HIS232E, HIS404F, HIS430F, HIS436F, HIS475F, HIS81E, ILE325E, ILE426F, ILE458F, ILE478F, ILE499F, ILE523F, ILE539F, LEU187E, LEU235E, LEU244E, LEU299E, LEU300E, LEU304E, LEU314E, LEU331E, LEU34F, LEU414F, LEU459F, LEU502F, LEU509F, LEU512F, LEU517F, LEU531F, LEU541F, LEU80E, LEU82E, LYS192E, LYS241E, LYS492F, LYS532F, PHE105E, PHE112E, PHE242E, PHE252E, PHE292E, PHE295E, PHE333E, PHE373E, PHE411E, PHE498F, PHE508F, PHE58E, PRO109E, PRO205E, PRO239E, PRO248E, PRO28E, PRO28F, PRO429F, PRO472F, PRO513F, PRO83E, PRO89E, SER106E, SER212E, SER229F, SER27E, SER27F, SER293E, SER428F, SER507F, SER524F, SER542F, SER543F, SER84E, SER86E, THR111E, THR193E, THR297E, THR310E, THR493F, THR501F, THR506F, THR538F, TRP211E, TRP431F, TYR210E, TYR213E, TYR243E, TYR427F, TYR521F, TYR533F, TYR85E, VAL100E, VAL104E, VAL208E, VAL228E, VAL291E, VAL306E, VAL327E, VAL334E, VAL433F, VAL448F, VAL450F, VAL451F, VAL471F, VAL477F, VAL516F, VAL68F