3FUB

crystal structure of gdnf-gfralpha1 complex

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 79
  • Norm. En. per Res.: -3.7135
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-35.5285	-15.2218	-222.719	-273.4694	81	6	5	9350	6	41	37
A-C	-30.4054	43.9534	-88.9951	-75.447	64	8	3	4066	1	28	27
B-C	-16.23	0.0	-16.4732	-32.7032	17	1	0	882	0	1	4
C-D	-37.0248	-44.6254	-211.715	-293.3652	79	13	5	9181	7	47	37

Interface residues

• A-B: ALA157A, ALA158A, ALA160A, ALA173A, ALA220A, ARG124B, ARG171A, ARG224A, ARG225A, ARG226A, ARG66B, ASN117B, ASN152A, ASN162A, ASN49B, ASP108B, ASP109B, ASP110B, ASP115B, ASP116B, ASP156A, ASP164A, ASP165A, CYS154A, CYS161A, CYS167A, CYS178A, CYS221A, GLN227A, GLU223A, GLU61B, GLU62B, GLY151A, HIS121B, HIS126B, HIS47B, ILE122B, ILE175A, ILE219A, ILE229A, ILE46B, ILE64B, LEU111B, LEU114B, LEU118B, LEU123B, LEU155A, LEU163A, LEU196A, LEU48B, LEU63B, LYS129B, LYS150A, LYS159A, LYS168A, LYS169A, LYS60B, MET182A, MET211A, PHE113B, PHE65B, PRO177A, PRO231A, SER112B, SER127B, SER172A, SER181A, THR166A, THR176A, THR179A, THR180A, THR222A, THR228A, THR59B, TYR120B, TYR170A, TYR174A, VAL119B, VAL230A, VAL232A, VAL50B
• A-C: ALA220A, ALA220C, ARG217A, ARG217C, ARG224A, ARG225C, ARG226A, ARG226C, ARG238A, ARG240A, ASN242A, ASN317A, ASN330C, ASP218A, ASP218C, ASP303A, ASP303C, ASP314A, ASP324C, ASP334C, CYS216C, CYS221A, CYS221C, CYS313A, CYS315A, CYS315C, CYS325C, GLN227A, GLU223A, GLU223C, GLU236A, GLU237A, GLU239A, GLU323C, GLY319A, ILE219A, ILE219C, LEU322A, LEU322C, LEU326C, LEU329A, LEU329C, LYS327C, LYS333A, LYS333C, PHE328C, PHE331C, PRO241A, SER275C, SER304A, SER304C, SER305A, SER305C, SER306A, SER306C, SER308C, SER316A, SER318A, THR222A, THR222C, THR336C, TRP312A, VAL302A, VAL302C
• B-C: ASN117B, ASN242C, ASN317C, ASN320C, ASP115B, ASP116B, CYS315C, GLU58B, GLY319C, LEU114B, LEU118B, LEU322C, LEU326C, LYS60B, SER316C, SER318C, VAL119B
• C-D: ALA158C, ALA160C, ALA173C, ALA220C, ARG124D, ARG171C, ARG224C, ARG225C, ARG226C, ARG66D, ASN117D, ASN152C, ASN162C, ASN49D, ASP108D, ASP109D, ASP110D, ASP115D, ASP116D, ASP156C, ASP164C, ASP165C, CYS154C, CYS161C, CYS167C, CYS178C, CYS221C, GLN227C, GLU223C, GLU58D, GLU61D, GLU62D, GLY151C, HIS121D, HIS126D, HIS47D, ILE122D, ILE175C, ILE219C, ILE229C, ILE64D, LEU111D, LEU114D, LEU118D, LEU123D, LEU155C, LEU163C, LEU48D, LEU63D, LYS129D, LYS150C, LYS159C, LYS168C, LYS169C, LYS60D, MET211C, PHE113D, PHE65D, PRO177C, PRO231C, SER112D, SER127D, SER172C, SER181C, SER304C, THR166C, THR176C, THR179C, THR180C, THR222C, THR228C, THR59D, TYR120D, TYR170C, TYR174C, VAL119D, VAL230C, VAL232C, VAL50D