3FRP

crystal structure of cobra venom factor, a co-factor for c3- and c5 convertase cvfbb

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-G
  • Int. Res.: 227
  • Norm. En. per Res.: -3.2166
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-G	-330.5583	-32.9203	-366.679	-730.1576	227	67	39	38260	4	57	47
A-B	-15.5656	-24.8165	-162.288	-202.6701	91	11	4	7015	1	17	9
G-B	-227.7093	-73.0948	-10.9033	-311.7074	194	46	18	28106	6	34	30

Interface residues

• A-G: ALA539A, ALA540A, ALA551A, ALA557A, ALA561A, ALA574A, ALA769G, ALA781G, ALA812G, ALA857G, ARG124A, ARG195A, ARG228A, ARG552A, ARG726G, ARG759G, ARG787G, ARG811G, ARG856G, ASN159A, ASN532A, ASN745G, ASN816G, ASP111A, ASP168A, ASP305A, ASP491A, ASP531A, ASP548A, ASP559A, ASP728G, ASP739G, ASP760G, ASP795G, ASP885G, CYS522A, CYS779G, GLN109A, GLN535A, GLN573A, GLN747G, GLN797G, GLN899G, GLN944G, GLU203A, GLU233A, GLU234A, GLU236A, GLU301A, GLU546A, GLU742G, GLU743G, GLU782G, GLU785G, GLU936G, GLU938G, GLY118A, GLY148A, GLY232A, GLY303A, GLY524A, GLY530A, GLY538A, GLY547A, GLY550A, GLY554A, GLY748G, GLY777G, HIS815G, ILE108A, ILE114A, ILE149A, ILE534A, ILE543A, ILE571A, ILE576A, ILE749G, ILE762G, ILE778G, ILE786G, ILE794G, ILE810G, ILE813G, ILE937G, ILE942G, ILE943G, LEU106A, LEU122A, LEU150A, LEU158A, LEU169A, LEU172A, LEU199A, LEU230A, LEU526A, LEU533A, LEU545A, LEU555A, LEU565A, LEU734G, LEU736G, LEU740G, LEU758G, LEU768G, LEU796G, LEU814G, LEU853G, LEU891G, LYS112A, LYS196A, LYS464A, LYS529A, LYS542A, LYS544A, LYS560A, LYS570A, LYS575A, LYS731G, LYS738G, LYS752G, LYS776G, LYS790G, LYS889G, LYS892G, LYS940G, MET128A, MET299A, MET306A, MET523A, MET536A, MET541A, MET754G, MET789G, MET798G, PHE105A, PHE107A, PHE126A, PHE160A, PHE161A, PHE202A, PHE729G, PHE756G, PHE772G, PHE792G, PHE793G, PRO117A, PRO120A, PRO163A, PRO167A, PRO200A, PRO490A, PRO537A, PRO549A, PRO730G, PRO744G, PRO774G, PRO783G, PRO799G, PRO895G, SER119A, SER127A, SER201A, SER302A, SER304A, SER572A, SER727G, SER732G, SER750G, SER751G, SER755G, SER761G, SER771G, SER801G, SER854G, SER855G, THR110A, THR116A, THR145A, THR300A, THR521A, THR525A, THR737G, THR741G, THR753G, THR763G, THR764G, THR773G, THR775G, THR939G, TRP577A, TRP733G, TRP735G, TRP765G, TRP883G, TYR115A, TYR123A, TYR197A, TYR229A, TYR231A, TYR563A, TYR757G, TYR784G, TYR800G, TYR817G, VAL121A, VAL125A, VAL151A, VAL170A, VAL194A, VAL198A, VAL235A, VAL307A, VAL527A, VAL528A, VAL553A, VAL556A, VAL558A, VAL562A, VAL564A, VAL766G, VAL767G, VAL770G, VAL780G, VAL788G, VAL791G, VAL858G, VAL894G
• A-B: ALA1400B, ALA239A, ARG1279B, ARG1384B, ARG1388B, ARG260A, ASN1308B, ASN1406B, ASN1441B, ASP1361B, ASP1383B, ASP1443B, ASP168A, ASP256A, ASP265A, ASP305A, GLU1282B, GLU236A, GLU301A, GLY1381B, GLY237A, GLY303A, ILE1359B, ILE1360B, ILE1362B, ILE1386B, ILE1402B, ILE1403B, ILE149A, ILE254A, ILE261A, ILE263A, ILE264A, LEU1304B, LEU1405B, LEU1442B, LEU150A, LEU169A, LEU242A, LEU258A, LYS1284B, LYS1398B, LYS1407B, LYS1435B, LYS1445B, MET1357B, MET299A, MET306A, PHE1306B, PHE240A, PHE243A, PRO167A, PRO255A, PRO262A, SER1363B, SER1387B, SER1438B, SER152A, SER171A, SER253A, SER257A, SER295A, SER302A, SER304A, THR1280B, THR1305B, THR1356B, THR1358B, THR259A, THR297A, THR300A, TYR1307B, TYR1385B, TYR1389B, TYR1404B, TYR1437B, TYR1439B, TYR1440B, TYR164A, TYR293A, VAL1382B, VAL1399B, VAL1401B, VAL151A, VAL170A, VAL238A, VAL241A, VAL296A, VAL298A, VAL307A, VAL308A
• G-B: ALA1293B, ALA1299B, ALA1309B, ALA1396B, ALA1400B, ALA1471B, ALA812G, ALA833G, ALA837G, ALA852G, ALA857G, ALA925G, ARG1279B, ARG1469B, ARG811G, ARG845G, ARG856G, ARG926G, ASN1271B, ASN1286B, ASN1308B, ASN1460B, ASN1466B, ASN1497B, ASN1582B, ASN805G, ASN831G, ASP1254B, ASP1288B, ASP1361B, ASP1392B, ASP909G, ASP946G, CYS1463B, CYS1468B, CYS1470B, CYS835G, GLN1287B, GLN1310B, GLN1397B, GLN1430B, GLN807G, GLN842G, GLN846G, GLN847G, GLN867G, GLN899G, GLN919G, GLN944G, GLU1258B, GLU1282B, GLU1390B, GLU806G, GLU809G, GLU866G, GLU896G, GLU921G, GLU936G, GLU938G, GLY1367B, GLY1427B, GLY1432B, GLY1457B, GLY1465B, GLY1472B, GLY841G, GLY897G, GLY945G, HIS1423B, HIS1451B, ILE1255B, ILE1257B, ILE1270B, ILE1289B, ILE1303B, ILE1362B, ILE1402B, ILE1429B, ILE1462B, ILE1464B, ILE810G, ILE813G, ILE850G, ILE862G, ILE902G, ILE905G, ILE923G, ILE937G, ILE941G, ILE942G, ILE943G, LEU1251B, LEU1253B, LEU1259B, LEU1285B, LEU1304B, LEU1365B, LEU1369B, LEU1458B, LEU1459B, LEU1569B, LEU828G, LEU865G, LEU908G, LEU920G, LYS1284B, LYS1398B, LYS1435B, LYS1445B, LYS1448B, LYS1461B, LYS1581B, LYS804G, LYS840G, LYS851G, LYS900G, LYS907G, LYS924G, LYS940G, MET1301B, MET1364B, MET1395B, PHE1306B, PHE1368B, PHE1424B, PHE1428B, PHE1449B, PHE834G, PHE848G, PHE860G, PRO1260B, PRO1431B, PRO1570B, PRO799G, PRO832G, PRO849G, PRO859G, PRO864G, PRO895G, PRO910G, SER1294B, SER1363B, SER1433B, SER1564B, SER1566B, SER836G, SER838G, SER854G, SER855G, SER901G, THR1256B, THR1280B, THR1283B, THR1290B, THR1292B, THR1300B, THR1302B, THR1305B, THR1366B, THR1447B, THR1456B, THR1496B, THR839G, THR904G, THR918G, THR935G, THR939G, TYR1268B, TYR1307B, TYR1389B, TYR1437B, TYR1450B, TYR823G, TYR830G, TYR844G, VAL1281B, VAL1291B, VAL1317B, VAL1391B, VAL1399B, VAL1401B, VAL1426B, VAL1434B, VAL1467B, VAL803G, VAL808G, VAL858G, VAL861G, VAL863G, VAL894G, VAL898G, VAL903G, VAL906G, VAL922G