3FQU

phosphorylation of self-peptides alters human leukocyte antigen class i-restricted antigen presentation and generates tumor specific epitopes

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 120
  • Norm. En. per Res.: -4.0516
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-62.3489	-53.7409	-370.1	-486.1897	120	4	2	12344	5	44	42
A-C	-32.633	-1.8244	-238.948	-273.4054	80	11	7	8356	0	2	11

Interface residues

• A-B: ALA117A, ALA125A, ALA14B, ALA236A, ALA246A, ALA24A, ALA40A, ARG11B, ARG14A, ARG202A, ARG21A, ARG234A, ARG2B, ARG35A, ARG48A, ARG6A, ARG96B, ARG97A, ASN20B, ASN23B, ASP119A, ASP122A, ASP238A, ASP33B, ASP37A, ASP52B, ASP58B, ASP95B, ASP97B, CYS24B, GLN115A, GLN1B, GLN242A, GLN32A, GLN7B, GLN96A, GLU229A, GLU232A, GLU46A, GLY120A, GLY237A, GLY239A, GLY26A, GLY28B, HIS114A, HIS12B, HIS188A, HIS191A, HIS192A, HIS30B, HIS50B, HIS74A, HIS93A, ILE124A, ILE23A, ILE34B, ILE6B, LEU206A, LEU230A, LEU53B, LEU63B, LEU64B, LYS121A, LYS186A, LYS243A, LYS57B, LYS5B, MET98A, MET98B, PHE21B, PHE22A, PHE241A, PHE29B, PHE36A, PHE55B, PHE61B, PHE8A, PHE9A, PRO13B, PRO235A, PRO31B, SER10B, SER11A, SER13A, SER207A, SER27B, SER32B, SER51B, SER54B, SER56B, SER60B, SER92A, THR10A, THR190A, THR200A, THR233A, THR240A, THR94A, TRP204A, TRP244A, TRP59B, TRP94B, TYR116A, TYR118A, TYR123A, TYR25B, TYR27A, TYR62B, TYR65B, TYR66B, TYR7A, TYR99A, TYR9B, VAL12A, VAL231A, VAL25A, VAL26B, VAL34A, VAL8B, VAL95A
• A-C: ALA139A, ALA140A, ALA150A, ALA153A, ALA158A, ALA24A, ALA69A, ALA9C, ARG157A, ARG170A, ARG65A, ARG6A, ARG75A, ARG8C, ARG97A, ASP77A, CYS101A, CYS164A, GLN155A, GLN72A, GLU166A, GLU55A, GLU63A, GLY100A, GLY1C, GLY26A, GLY4C, GLY62A, HIS114A, HIS151A, HIS70A, HIS74A, ILE124A, ILE52A, LEU156A, LEU160A, LEU168A, LEU2C, LEU3C, LEU78A, LEU81A, LYS144A, LYS146A, LYS66A, LYS68A, MET45A, MET5A, PHE22A, PHE33A, PHE36A, PHE8A, PHE9A, PRO6C, SER71A, THR142A, THR143A, THR163A, THR64A, THR73A, THR80A, TRP133A, TRP147A, TRP167A, TRP51A, TYR116A, TYR123A, TYR159A, TYR171A, TYR59A, TYR7A, TYR84A, TYR99A, VAL152A, VAL25A, VAL28A, VAL34A, VAL67A, VAL76A, VAL7C, VAL95A