3FOK

crystal structure of cgl0159 from corynebacterium glutamicum (brevibacterium flavum). northeast structural genomics target cgr115

• Total interactions analyzed: 45
• Total true interactions: 20
• Strongest Interaction:
  • Chains: C-E
  • Int. Res.: 144
  • Norm. En. per Res.: -3.7762
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-74.6168	-17.6601	-414.635	-506.9119	139	12	12	16313	5	27	39
A-C	0.0	0.0	-3.1488	-3.1488	7	0	0	108	0	2	0
A-E	0.0	0.0	-2.2096	-2.2096	10	0	0	158	0	2	0
A-H	-84.0732	-20.0995	-419.534	-523.7067	140	14	12	16490	6	27	38
B-E	0.0	0.0	-31.2179	-31.2179	31	6	0	1571	0	2	1
B-F	-69.8214	6.9053	-407.606	-470.5221	142	12	12	16315	6	26	38
C-D	-85.6454	-20.3526	-425.484	-531.482	143	18	13	16648	5	26	39
C-E	-93.9382	-18.1879	-431.647	-543.7731	144	15	13	16708	5	28	39
C-G	0.0	0.0	-2.1929	-2.1929	16	0	0	305	0	2	0
C-H	0.0	0.0	13.2332	13.2332	27	4	0	1347	0	4	1
D-G	0.0	0.0	-5.0812	-5.0812	26	6	0	1338	0	4	1
D-I	-74.9793	4.0409	-405.946	-476.8844	143	11	12	16211	6	26	39
E-F	0.0	0.0	-0.3324	-0.3324	6	0	0	88	0	0	0
E-J	-82.687	-16.3457	-403.79	-502.8227	142	11	12	16199	6	26	39
F-G	-81.1134	-16.329	-420.562	-518.0044	141	12	12	16508	5	27	38
F-I	0.0	0.0	-1.9314	-1.9314	9	0	0	147	0	1	0
F-J	0.0	0.0	-31.6531	-31.6531	29	6	0	1575	0	2	1
G-H	-76.443	7.7295	-407.486	-476.1995	141	12	12	16162	6	26	39
G-I	0.0	0.0	-2.8373	-2.8373	6	0	0	102	0	2	0
I-J	-76.3809	10.1323	-420.993	-487.2415	146	12	12	16448	6	28	38

Interface residues

• A-B: ALA100B, ALA121B, ALA13B, ALA156A, ALA159A, ALA164A, ALA164B, ALA166A, ALA173A, ALA174A, ALA19B, ALA207A, ALA209A, ALA20B, ALA210A, ALA26B, ALA53B, ALA56B, ALA67B, ARG115B, ARG119B, ARG128A, ARG128B, ARG140B, ARG150A, ARG15B, ARG16B, ARG18B, ARG231A, ARG268A, ARG54B, ARG69B, ASN133B, ASN152A, ASN170A, ASN214A, ASN62B, ASN68B, ASP126A, ASP126B, ASP127B, ASP139B, ASP155A, ASP200A, ASP215A, ASP50B, ASP93B, ASP96B, ASP97B, GLN176A, GLN204A, GLU124B, GLU12B, GLU163A, GLU21B, GLU228A, GLU230A, GLU234A, GLU27B, GLU36A, GLU63B, GLU71B, GLY116B, GLY117B, GLY120B, GLY131B, GLY157A, GLY211A, GLY213A, GLY266A, GLY39A, GLY42A, GLY55B, HIS167A, HIS51B, ILE151A, ILE203A, ILE208A, ILE6B, ILE94B, ILE95B, LEU101B, LEU118B, LEU14B, LEU153A, LEU162A, LEU212A, LEU264A, LEU37A, LEU38A, LEU57B, LEU72B, LEU73B, PHE11B, PHE123B, PHE144A, PHE29B, PRO160A, PRO178A, PRO22B, PRO239A, PRO265A, PRO52B, PRO92B, SER112B, SER122B, SER135B, SER136B, SER154A, SER205A, SER216A, SER217A, SER235A, THR130B, THR158A, THR161A, THR165A, THR199A, THR219A, THR236A, THR237A, THR23B, THR240A, THR64B, THR91B, TRP188B, TRP220A, TYR129B, TYR132B, TYR218A, TYR70B, VAL134B, VAL142B, VAL149A, VAL169A, VAL206A, VAL232A, VAL25B, VAL267A
• A-C: ASN190A, ASN62C, GLU63C, GLY191A, LYS192A, THR64C, VAL189A
• A-E: ARG231E, ASN190A, ASP200E, GLU227E, GLU228E, GLY191A, SER198E, THR199E, TRP188A, VAL189A
• A-H: ALA100A, ALA121A, ALA13A, ALA156H, ALA159H, ALA164A, ALA164H, ALA166H, ALA173H, ALA174H, ALA19A, ALA201H, ALA207H, ALA209H, ALA20A, ALA210H, ALA26A, ALA53A, ALA56A, ALA67A, ARG115A, ARG119A, ARG128A, ARG128H, ARG140A, ARG150H, ARG15A, ARG16A, ARG18A, ARG231H, ARG268H, ARG54A, ARG69A, ASN133A, ASN152H, ASN170H, ASN214H, ASN62A, ASN68A, ASP126A, ASP126H, ASP127A, ASP139A, ASP155H, ASP200H, ASP215H, ASP50A, ASP93A, ASP96A, ASP97A, GLN176H, GLN204H, GLU124A, GLU12A, GLU163H, GLU21A, GLU228H, GLU230H, GLU234H, GLU27A, GLU63A, GLU71A, GLY116A, GLY117A, GLY120A, GLY131A, GLY157H, GLY211H, GLY213H, GLY266H, GLY39H, GLY42H, GLY55A, HIS167H, HIS51A, ILE151H, ILE203H, ILE208H, ILE6A, ILE94A, ILE95A, LEU101A, LEU118A, LEU14A, LEU153H, LEU162H, LEU177H, LEU212H, LEU264H, LEU37H, LEU38H, LEU57A, LEU72A, LEU73A, PHE11A, PHE123A, PHE144H, PHE29A, PRO160H, PRO178H, PRO22A, PRO239H, PRO265H, PRO52A, PRO92A, SER112A, SER122A, SER135A, SER136A, SER154H, SER205H, SER216H, SER217H, SER235H, THR130A, THR158H, THR161H, THR165H, THR199H, THR219H, THR236H, THR237H, THR23A, THR240H, THR64A, THR91A, TRP188A, TRP220H, TYR129A, TYR132A, TYR218H, TYR70A, VAL134A, VAL142A, VAL149H, VAL169H, VAL206H, VAL232H, VAL25A, VAL267H
• B-E: ALA121B, ALA156B, ALA58E, ARG119E, ASN152B, ASN187B, ASN190B, ASN190E, ASN62E, ASP155B, GLU124B, GLU246E, GLY157B, GLY191B, GLY191E, GLY248E, GLY60E, LEU153B, LYS192B, LYS192E, PHE123B, SER122B, SER154B, SER186B, TRP188B, VAL189B, VAL189E, VAL193B, VAL194B, VAL194E, VAL59E
• B-F: ALA100F, ALA121F, ALA156B, ALA159B, ALA164B, ALA164F, ALA166B, ALA173B, ALA174B, ALA19F, ALA201B, ALA207B, ALA209B, ALA20F, ALA210B, ALA26F, ALA53F, ALA56F, ALA67F, ARG115F, ARG119F, ARG128B, ARG128F, ARG140F, ARG150B, ARG15F, ARG16F, ARG18F, ARG231B, ARG268B, ARG54F, ARG69F, ASN133F, ASN152B, ASN170B, ASN214B, ASN62F, ASN68F, ASP126B, ASP126F, ASP127F, ASP139F, ASP155B, ASP200B, ASP215B, ASP50F, ASP93F, ASP96F, ASP97F, GLN176B, GLN204B, GLU124F, GLU12F, GLU163B, GLU171B, GLU21F, GLU230B, GLU234B, GLU27F, GLU36B, GLU63F, GLU71F, GLY116F, GLY117F, GLY120F, GLY131F, GLY157B, GLY211B, GLY213B, GLY266B, GLY39B, GLY42B, GLY55F, HIS167B, HIS51F, ILE151B, ILE203B, ILE208B, ILE6F, ILE94F, ILE95F, LEU101F, LEU118F, LEU14F, LEU153B, LEU162B, LEU177B, LEU212B, LEU264B, LEU37B, LEU38B, LEU57F, LEU72F, LEU73F, LYS43B, PHE11F, PHE123F, PHE144B, PHE29F, PRO160B, PRO160F, PRO178B, PRO22F, PRO239B, PRO265B, PRO52F, PRO92F, SER112F, SER122F, SER135F, SER136F, SER154B, SER205B, SER216B, SER217B, SER235B, THR130F, THR158B, THR161B, THR165B, THR199B, THR219B, THR236B, THR237B, THR23F, THR240B, THR64F, THR91F, TRP188F, TRP220B, TYR129F, TYR132F, TYR218B, TYR70F, VAL134F, VAL142F, VAL149B, VAL169B, VAL206B, VAL232B, VAL25F, VAL267B
• C-D: ALA100D, ALA121D, ALA156C, ALA159C, ALA164C, ALA164D, ALA166C, ALA173C, ALA174C, ALA19D, ALA201C, ALA207C, ALA209C, ALA20D, ALA210C, ALA26D, ALA53D, ALA56D, ALA67D, ALA99D, ARG115D, ARG119D, ARG128C, ARG128D, ARG140D, ARG150C, ARG15D, ARG16D, ARG18D, ARG231C, ARG268C, ARG54D, ARG69D, ASN133D, ASN152C, ASN170C, ASN214C, ASN62D, ASN68D, ASP126C, ASP126D, ASP127D, ASP139D, ASP155C, ASP200C, ASP215C, ASP50D, ASP93D, ASP96D, ASP97D, GLN176C, GLN204C, GLU124D, GLU12D, GLU163C, GLU21D, GLU228C, GLU230C, GLU234C, GLU27D, GLU63D, GLU71D, GLY116D, GLY117D, GLY120D, GLY131D, GLY157C, GLY211C, GLY213C, GLY266C, GLY39C, GLY42C, GLY55D, HIS167C, HIS51D, ILE151C, ILE203C, ILE208C, ILE6D, ILE94D, ILE95D, LEU101D, LEU118D, LEU14D, LEU153C, LEU162C, LEU177C, LEU212C, LEU264C, LEU37C, LEU38C, LEU44C, LEU57D, LEU72D, LEU73D, LEU98D, PHE11D, PHE123D, PHE144C, PHE29D, PRO160C, PRO160D, PRO178C, PRO22D, PRO239C, PRO265C, PRO52D, PRO92D, SER112D, SER122D, SER135D, SER136D, SER154C, SER205C, SER216C, SER217C, SER235C, THR130D, THR158C, THR161C, THR165C, THR199C, THR219C, THR236C, THR237C, THR23D, THR240C, THR64D, THR91D, TRP188D, TRP220C, TYR129D, TYR132D, TYR218C, TYR70D, VAL134D, VAL142D, VAL149C, VAL169C, VAL206C, VAL232C, VAL25D, VAL267C
• C-E: ALA100C, ALA121C, ALA13C, ALA156E, ALA159E, ALA164C, ALA164E, ALA166E, ALA173E, ALA174E, ALA19C, ALA207E, ALA209E, ALA20C, ALA210E, ALA26C, ALA53C, ALA56C, ALA67C, ARG115C, ARG119C, ARG128C, ARG128E, ARG140C, ARG150E, ARG15C, ARG16C, ARG18C, ARG231E, ARG268E, ARG54C, ARG69C, ASN133C, ASN152E, ASN170E, ASN214E, ASN62C, ASN68C, ASP126C, ASP126E, ASP127C, ASP139C, ASP155E, ASP200E, ASP215E, ASP50C, ASP93C, ASP96C, ASP97C, GLN176E, GLN204E, GLU124C, GLU12C, GLU163E, GLU171E, GLU21C, GLU228E, GLU230E, GLU234E, GLU27C, GLU36E, GLU63C, GLU71C, GLY116C, GLY117C, GLY120C, GLY131C, GLY157E, GLY211E, GLY213E, GLY266E, GLY39E, GLY42E, GLY55C, HIS167E, HIS51C, ILE151E, ILE203E, ILE208E, ILE6C, ILE94C, ILE95C, LEU101C, LEU118C, LEU14C, LEU153E, LEU162E, LEU177E, LEU212E, LEU264E, LEU37E, LEU38E, LEU44E, LEU57C, LEU72C, LEU73C, LYS43E, PHE11C, PHE123C, PHE144E, PHE29C, PRO160C, PRO160E, PRO178E, PRO22C, PRO239E, PRO265E, PRO52C, PRO92C, SER112C, SER122C, SER135C, SER136C, SER154E, SER205E, SER216E, SER217E, SER235E, THR130C, THR158E, THR161E, THR165E, THR199E, THR219E, THR236E, THR237E, THR23C, THR240E, THR64C, THR91C, TRP188C, TRP220E, TYR129C, TYR132C, TYR218E, TYR70C, VAL134C, VAL142C, VAL149E, VAL169E, VAL206E, VAL232E, VAL25C, VAL267E
• C-G: ALA156C, ALA156G, ASN190C, ASN190G, ASP155C, ASP155G, GLY191C, GLY191G, LEU153C, LEU153G, SER154C, SER154G, TRP188C, TRP188G, VAL189C, VAL189G
• C-H: ALA121H, ASN187C, ASN190C, ASN190H, ASN195C, ASP155H, ASP196C, GLU124H, GLU246C, GLY120H, GLY191C, GLY191H, GLY248C, LEU197C, LYS192C, LYS192H, PHE123H, SER122H, SER154H, SER198C, TRP188C, TRP188H, VAL189C, VAL189H, VAL193C, VAL193H, VAL194C
• D-G: ALA121D, ASN187G, ASN190D, ASN190G, ASN195G, ASP155D, ASP196G, GLU124D, GLU246G, GLY120D, GLY191D, GLY191G, LEU197G, LYS192D, LYS192G, PHE123D, SER122D, SER154D, SER198G, TRP188D, TRP188G, VAL189D, VAL189G, VAL193D, VAL193G, VAL194G
• D-I: ALA100I, ALA121I, ALA13I, ALA156D, ALA159D, ALA164D, ALA164I, ALA166D, ALA173D, ALA174D, ALA19I, ALA207D, ALA209D, ALA20I, ALA210D, ALA26I, ALA53I, ALA56I, ALA67I, ARG115I, ARG119I, ARG128D, ARG128I, ARG140I, ARG150D, ARG15I, ARG16I, ARG18I, ARG231D, ARG268D, ARG54I, ARG69I, ASN114I, ASN133I, ASN152D, ASN170D, ASN214D, ASN62I, ASN68I, ASP126D, ASP126I, ASP127I, ASP139I, ASP155D, ASP200D, ASP215D, ASP50I, ASP93I, ASP96I, ASP97I, GLN176D, GLN204D, GLU124I, GLU12I, GLU163D, GLU171D, GLU21I, GLU230D, GLU234D, GLU27I, GLU36D, GLU63I, GLU71I, GLY116I, GLY117I, GLY120I, GLY131I, GLY157D, GLY211D, GLY213D, GLY266D, GLY39D, GLY42D, GLY55I, HIS167D, HIS51I, ILE151D, ILE203D, ILE208D, ILE94I, ILE95I, LEU101I, LEU118I, LEU14I, LEU153D, LEU162D, LEU177D, LEU212D, LEU264D, LEU37D, LEU38D, LEU44D, LEU57I, LEU72I, LEU73I, LYS43D, PHE11I, PHE123I, PHE144D, PHE29I, PRO160D, PRO160I, PRO178D, PRO22I, PRO239D, PRO265D, PRO52I, PRO92I, SER112I, SER122I, SER135I, SER136I, SER154D, SER205D, SER216D, SER217D, SER235D, THR130I, THR158D, THR161D, THR165D, THR199D, THR219D, THR236D, THR237D, THR23I, THR240D, THR64I, THR91I, TRP188I, TRP220D, TYR129I, TYR132I, TYR218D, TYR70I, VAL134I, VAL142I, VAL149D, VAL169D, VAL206D, VAL232D, VAL25I, VAL267D
• E-F: ASN190E, ASN190F, GLY191E, GLY191F, SER122E, SER122F
• E-J: ALA100E, ALA121E, ALA13E, ALA156J, ALA159J, ALA164E, ALA164J, ALA166J, ALA173J, ALA174J, ALA19E, ALA201J, ALA207J, ALA209J, ALA20E, ALA210J, ALA26E, ALA53E, ALA56E, ALA67E, ARG115E, ARG119E, ARG128E, ARG128J, ARG140E, ARG150J, ARG15E, ARG16E, ARG18E, ARG231J, ARG268J, ARG54E, ARG69E, ASN133E, ASN152J, ASN170J, ASN214J, ASN62E, ASN68E, ASP126E, ASP126J, ASP127E, ASP139E, ASP155J, ASP200J, ASP215J, ASP50E, ASP93E, ASP96E, ASP97E, GLN176J, GLN204J, GLU124E, GLU12E, GLU163J, GLU21E, GLU228J, GLU230J, GLU234J, GLU27E, GLU63E, GLU71E, GLY116E, GLY117E, GLY120E, GLY131E, GLY157J, GLY211J, GLY213J, GLY266J, GLY42J, GLY55E, HIS167J, HIS51E, ILE151J, ILE203J, ILE208J, ILE6E, ILE94E, ILE95E, LEU101E, LEU118E, LEU14E, LEU153J, LEU162J, LEU177J, LEU212J, LEU264J, LEU37J, LEU38J, LEU44J, LEU57E, LEU72E, LEU73E, LYS43J, PHE11E, PHE123E, PHE144J, PHE29E, PRO160E, PRO160J, PRO178J, PRO22E, PRO239J, PRO265J, PRO52E, PRO92E, SER112E, SER122E, SER135E, SER136E, SER154J, SER205J, SER216J, SER217J, SER235J, THR130E, THR158J, THR161J, THR165J, THR199J, THR219J, THR236J, THR237J, THR23E, THR240J, THR64E, THR91E, TRP188E, TRP220J, TYR129E, TYR132E, TYR218J, TYR70E, VAL134E, VAL142E, VAL149J, VAL169J, VAL206J, VAL232J, VAL25E, VAL267J
• F-G: ALA100G, ALA121G, ALA13G, ALA156F, ALA159F, ALA164F, ALA164G, ALA166F, ALA173F, ALA174F, ALA19G, ALA207F, ALA209F, ALA20G, ALA210F, ALA26G, ALA53G, ALA56G, ALA67G, ARG115G, ARG119G, ARG128F, ARG128G, ARG140G, ARG150F, ARG15G, ARG16G, ARG18G, ARG231F, ARG268F, ARG54G, ARG69G, ASN133G, ASN152F, ASN170F, ASN214F, ASN62G, ASN68G, ASP126F, ASP126G, ASP127G, ASP139G, ASP155F, ASP200F, ASP215F, ASP50G, ASP93G, ASP96G, ASP97G, GLN176F, GLN204F, GLU124G, GLU12G, GLU163F, GLU21G, GLU228F, GLU230F, GLU234F, GLU27G, GLU36F, GLU63G, GLU71G, GLY116G, GLY117G, GLY120G, GLY131G, GLY157F, GLY211F, GLY213F, GLY266F, GLY42F, GLY55G, HIS167F, HIS51G, ILE151F, ILE203F, ILE208F, ILE94G, ILE95G, LEU101G, LEU118G, LEU14G, LEU153F, LEU162F, LEU177F, LEU212F, LEU264F, LEU37F, LEU38F, LEU44F, LEU57G, LEU72G, LEU73G, LYS43F, PHE11G, PHE123G, PHE144F, PHE29G, PRO160F, PRO160G, PRO178F, PRO22G, PRO239F, PRO265F, PRO52G, PRO92G, SER112G, SER122G, SER135G, SER136G, SER154F, SER205F, SER216F, SER217F, SER235F, THR130G, THR158F, THR161F, THR165F, THR199F, THR219F, THR236F, THR237F, THR23G, THR240F, THR64G, THR91G, TRP188G, TRP220F, TYR129G, TYR132G, TYR218F, TYR70G, VAL134G, VAL142G, VAL149F, VAL169F, VAL206F, VAL232F, VAL25G, VAL267F
• F-I: ARG231F, ASN190I, ASP200F, GLU227F, GLU228F, GLY191I, SER198F, THR199F, VAL189I
• F-J: ALA156J, ALA58F, ARG119F, ASN152J, ASN187J, ASN190F, ASN190J, ASN62F, ASP155J, GLU124J, GLU246F, GLY157J, GLY191F, GLY191J, GLY248F, GLY60F, LEU153J, LYS192F, LYS192J, SER122J, SER154J, SER186J, TRP188J, VAL189F, VAL189J, VAL193J, VAL194F, VAL194J, VAL59F
• G-H: ALA100H, ALA121H, ALA156G, ALA159G, ALA164G, ALA164H, ALA166G, ALA173G, ALA174G, ALA19H, ALA201G, ALA207G, ALA209G, ALA20H, ALA210G, ALA26H, ALA53H, ALA56H, ALA67H, ARG115H, ARG119H, ARG128G, ARG128H, ARG140H, ARG150G, ARG15H, ARG16H, ARG18H, ARG231G, ARG268G, ARG54H, ARG69H, ASN133H, ASN152G, ASN170G, ASN214G, ASN62H, ASN68H, ASP126G, ASP126H, ASP127H, ASP139H, ASP155G, ASP200G, ASP215G, ASP50H, ASP93H, ASP96H, ASP97H, GLN176G, GLN204G, GLU124H, GLU12H, GLU163G, GLU21H, GLU228G, GLU230G, GLU234G, GLU27H, GLU63H, GLU71H, GLY116H, GLY117H, GLY120H, GLY131H, GLY157G, GLY211G, GLY213G, GLY266G, GLY42G, GLY55H, HIS167G, HIS51H, ILE151G, ILE203G, ILE208G, ILE6H, ILE94H, ILE95H, LEU101H, LEU118H, LEU14H, LEU153G, LEU162G, LEU177G, LEU212G, LEU264G, LEU37G, LEU38G, LEU44G, LEU57H, LEU72H, LEU73H, LYS43G, PHE11H, PHE123H, PHE144G, PHE29H, PRO160G, PRO160H, PRO178G, PRO22H, PRO239G, PRO265G, PRO52H, PRO92H, SER112H, SER122H, SER135H, SER136H, SER154G, SER205G, SER216G, SER217G, SER235G, THR130H, THR158G, THR161G, THR165G, THR199G, THR219G, THR236G, THR237G, THR23H, THR240G, THR64H, THR91H, TRP188H, TRP220G, TYR129H, TYR132H, TYR218G, TYR70H, VAL134H, VAL142H, VAL149G, VAL169G, VAL206G, VAL232G, VAL25H, VAL267G
• G-I: ASN190I, ASN62G, GLU63G, GLY191I, LYS192I, VAL189I
• I-J: ALA100J, ALA121J, ALA156I, ALA159I, ALA164I, ALA164J, ALA166I, ALA173I, ALA174I, ALA19J, ALA201I, ALA207I, ALA209I, ALA20J, ALA210I, ALA26J, ALA53J, ALA56J, ALA58J, ALA65J, ALA67J, ARG115J, ARG119J, ARG128I, ARG128J, ARG140J, ARG150I, ARG15J, ARG16J, ARG18J, ARG231I, ARG268I, ARG54J, ARG69J, ASN133J, ASN152I, ASN170I, ASN214I, ASN62J, ASN68J, ASP126I, ASP126J, ASP127J, ASP139J, ASP155I, ASP200I, ASP215I, ASP50J, ASP93J, ASP96J, ASP97J, GLN176I, GLN204I, GLU124J, GLU12J, GLU163I, GLU171I, GLU21J, GLU230I, GLU234I, GLU27J, GLU36I, GLU63J, GLU71J, GLY116J, GLY117J, GLY120J, GLY131J, GLY157I, GLY211I, GLY213I, GLY266I, GLY39I, GLY42I, GLY55J, HIS167I, HIS51J, ILE151I, ILE203I, ILE208I, ILE6J, ILE94J, ILE95J, LEU101J, LEU118J, LEU14J, LEU153I, LEU162I, LEU177I, LEU212I, LEU264I, LEU37I, LEU38I, LEU44I, LEU57J, LEU72J, LEU73J, LYS30J, LYS43I, PHE11J, PHE123J, PHE144I, PHE29J, PRO160I, PRO160J, PRO178I, PRO22J, PRO239I, PRO265I, PRO52J, PRO92J, SER112J, SER122J, SER135J, SER136J, SER154I, SER205I, SER216I, SER217I, SER235I, THR130J, THR158I, THR161I, THR165I, THR199I, THR219I, THR236I, THR237I, THR23J, THR240I, THR64J, THR91J, TRP188J, TRP220I, TYR129J, TYR132J, TYR218I, TYR70J, VAL134J, VAL142J, VAL149I, VAL169I, VAL206I, VAL232I, VAL25J, VAL267I