3FM8

crystal structure of full length centaurin alpha-1 bound with the fha domain of kif13b (capri target)

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 68
  • Norm. En. per Res.: -3.421
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-16.1435	0.0	-208.133	-224.2765	69	4	2	7280	0	16	15
A-D	0.0	0.0	-41.7538	-41.7538	40	1	1	2039	0	4	5
B-C	0.0	0.0	-42.5562	-42.5562	37	3	1	2108	0	5	6
B-D	-37.6596	0.9123	-195.88	-232.6272	68	6	2	6985	0	16	12
C-D	-78.0903	-39.9542	-149.919	-267.9635	83	9	0	6103	7	76	59

Interface residues

• A-C: ALA187C, ALA455A, ALA458A, ARG139C, ARG149C, ARG165C, ARG512A, ARG531A, ARG541A, ASN143C, ASN452A, ASN454A, ASN50C, ASN516A, ASN536A, ASN537A, ASP214C, ASP287C, ASP456A, ASP530A, CYS101C, GLN102C, GLN145C, GLN185C, GLU106C, GLU213C, GLU461A, GLY140C, GLY144C, GLY190C, GLY194C, GLY215C, GLY517A, GLY529A, GLY535A, HIS191C, HIS193C, HIS212C, HIS538A, ILE189C, ILE532A, LEU103C, LEU147C, LEU289C, LEU453A, LEU459A, LEU462A, LEU463A, LEU533A, LYS138C, LYS188C, MET486A, PHE146C, PHE514A, PHE539A, PHE540A, PRO186C, PRO192C, PRO288C, PRO457A, SER148C, SER518A, SER519A, THR513A, TRP137C, TYR211C, VAL451A, VAL464A, VAL515A
• A-D: ALA476A, ALA68D, ALA74D, ALA81D, ARG512A, ARG84D, ASN477A, ASN510A, ASN536A, ASN537A, CYS484A, GLN116D, GLN482A, GLN69D, GLU491A, GLU67D, GLU71D, GLY485A, GLY487A, HIS538A, HIS76D, ILE119D, ILE488A, LEU36D, LEU489A, LYS112D, LYS56D, MET486A, MET73D, PHE72D, PHE85D, PRO490A, SER475A, SER75D, THR35D, TYR113D, TYR120D, TYR34D, VAL54D, VAL70D
• B-C: ALA476B, ALA68C, ALA74C, ARG84C, ASN477B, ASN510B, ASN536B, ASN537B, CYS484B, GLN116C, GLN482B, GLN508B, GLN69C, GLU491B, GLU67C, GLU71C, GLY485B, GLY487B, HIS538B, HIS76C, ILE119C, ILE488B, LEU36C, LEU489B, LYS56C, MET486B, MET73C, PHE72C, PHE85C, PRO490B, SER475B, SER75C, THR35C, TYR113C, TYR120C, TYR34C, VAL70C
• B-D: ALA187D, ALA455B, ALA458B, ARG139D, ARG149D, ARG165D, ARG512B, ARG531B, ARG541B, ASN143D, ASN452B, ASN454B, ASN516B, ASN536B, ASN537B, ASP214D, ASP287D, ASP456B, ASP530B, CYS101D, GLN102D, GLN145D, GLN185D, GLU213D, GLU461B, GLY140D, GLY144D, GLY190D, GLY194D, GLY215D, GLY517B, GLY529B, GLY535B, HIS191D, HIS193D, HIS212D, HIS538B, ILE189D, ILE532B, LEU103D, LEU147D, LEU289D, LEU453B, LEU459B, LEU462B, LEU463B, LEU533B, LYS138D, LYS188D, MET486B, PHE146D, PHE209D, PHE514B, PHE539B, PHE540B, PRO186D, PRO192D, PRO288D, PRO457B, SER148D, SER518B, SER519B, THR513B, TRP137D, TYR211D, VAL451B, VAL464B, VAL515B
• C-D: ALA129C, ALA129D, ARG110C, ARG110D, ARG115C, ARG115D, ARG132C, ARG132D, ARG49C, ARG49D, ASN50C, ASN50D, ASP214C, ASP214D, ASP220C, ASP220D, GLN107C, GLN107D, GLN116C, GLN116D, GLN124C, GLN53C, GLN53D, GLU114C, GLU114D, GLU117C, GLU117D, GLU122C, GLU122D, GLU125C, GLU125D, GLU133C, GLU133D, GLU213C, GLU213D, GLU217C, GLU217D, GLY134C, GLY134D, GLY215C, GLY215D, GLY46D, HIS193C, HIS193D, HIS212C, HIS212D, HIS48C, HIS48D, ILE119C, ILE119D, ILE218C, ILE218D, ILE47D, ILE51C, ILE51D, LEU136C, LEU136D, LYS123C, LYS123D, LYS216C, LYS216D, LYS88C, LYS88D, PHE135C, PHE135D, PRO121C, PRO121D, PRO126C, PRO126D, PRO52C, PRO52D, SER128D, TRP137C, TRP137D, TRP221C, TRP221D, TYR120C, TYR120D, TYR127D, TYR131C, TYR131D, VAL54C, VAL54D