3FM7

quaternary structure of drosophila melanogaster ic/tctex-1/lc8; allosteric interactions of dynein light chains with dynein intermediate chain

• Total interactions analyzed: 15
• Total true interactions: 11
• Strongest Interaction:
  • Chains: C-E
  • Int. Res.: 48
  • Norm. En. per Res.: -5.9121
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-77.7856	-17.5695	-485.783	-581.1381	135	53	16	18454	3	9	8
A-C	-51.8806	0.0	-206.946	-258.8266	54	27	4	7782	0	2	3
A-D	0.0	0.4878	-40.4306	-39.9428	48	3	2	2293	0	3	3
A-E	0.0	0.0	-0.0018	-0.0018	2	0	0	2	0	0	1
B-C	-7.2676	0.0	-12.4132	-19.6808	48	22	1	2017	0	2	1
B-D	-37.6593	0.0	-224.249	-261.9083	59	21	6	7706	0	2	2
C-E	-72.3419	-2.0736	-209.364	-283.7795	48	22	0	7229	1	6	8
C-F	0.0	0.0	-42.0136	-42.0136	35	7	0	1744	0	2	4
D-E	-12.1162	0.0	-41.8431	-53.9593	34	1	0	1734	0	3	4
D-F	-72.0133	3.509	-198.271	-266.7754	46	19	0	7153	1	3	7
E-F	-123.603	6.0379	-314.901	-432.466	81	26	10	11303	0	9	19

Interface residues

• A-B: ALA110A, ALA110B, ALA65A, ALA65B, ALA73A, ALA73B, ALA78A, ALA78B, ASN38A, ASN38B, ASN39B, ASN47B, ASN71A, ASN71B, ASN84A, ASN84B, ASN85A, ASN85B, ASP35A, ASP35B, ASP86B, ASP88A, ASP88B, CYS102A, CYS102B, CYS48B, CYS81A, CYS81B, GLN33A, GLN33B, GLN43A, GLN43B, GLN56A, GLN56B, GLN69A, GLN69B, GLU46A, GLU46B, GLY108A, GLY108B, GLY42A, GLY42B, GLY72A, GLY72B, GLY74A, GLY74B, GLY89A, GLY89B, HIS34A, HIS34B, HIS76A, HIS76B, ILE103A, ILE103B, ILE62A, ILE62B, ILE67A, ILE67B, LEU109A, LEU109B, LEU49A, LEU49B, LEU52A, LEU52B, LEU75A, LEU75B, LYS36A, LYS36B, LYS54A, LYS57A, LYS57B, LYS60A, LYS60B, LYS70A, LYS70B, MET100A, MET100B, MET66A, MET66B, MET68A, MET68B, PHE107A, PHE107B, PRO58A, PRO58B, SER105A, SER105B, SER79A, SER79B, SER80A, SER80B, SER90A, SER90B, THR41A, THR41B, THR50A, THR50B, THR53A, THR53B, THR64A, THR64B, THR77A, THR77B, THR87A, THR87B, THR92B, THR99B, TRP40A, TRP40B, TRP83A, TRP83B, TYR101A, TYR101B, TYR32A, TYR32B, TYR59A, TYR59B, TYR61A, TYR61B, TYR82A, TYR82B, VAL104A, VAL104B, VAL106A, VAL106B, VAL111A, VAL111B, VAL37A, VAL37B, VAL44A, VAL44B, VAL45A, VAL45B, VAL63A, VAL63B
• A-C: ALA110A, ALA117C, ALA73A, ALA78A, ARG94A, ASN109C, ASN114C, ASN119C, ASN71A, ASN84A, ASN85A, ASP86A, ASP88A, CYS102A, CYS81A, CYS91A, GLN116C, GLU124C, GLU96A, GLY72A, GLY74A, GLY89A, HIS76A, ILE103A, ILE120C, LEU109A, LEU110C, LEU75A, LYS123C, LYS70A, MET68A, PHE107A, PRO121C, PRO122C, SER105A, SER111C, SER79A, SER80A, SER90A, THR118C, THR125C, THR77A, THR87A, THR92A, TRP83A, TYR101A, TYR113C, TYR82A, VAL104A, VAL106A, VAL112C, VAL115C, VAL12A, VAL93A
• A-D: ALA110A, ALA117D, ALA65A, ASN109D, ASN119D, ASN38A, ASN71A, ASP35A, GLN116D, GLN33A, GLN43A, GLN56A, GLN69A, GLU124D, GLU46A, GLY42A, HIS34A, ILE120D, ILE62A, ILE67A, LEU110D, LEU49A, LYS123D, LYS57A, LYS60A, LYS70A, MET66A, MET68A, PRO121D, PRO122D, PRO58A, SER111D, THR118D, THR125D, THR41A, THR50A, THR53A, THR64A, TYR113D, TYR32A, TYR59A, TYR61A, VAL111A, VAL112D, VAL115D, VAL37A, VAL45A, VAL63A
• A-E: ASN51E, LYS98A
• B-C: ALA110B, ALA117C, ALA65B, ASN109C, ASN114C, ASN119C, ASN38B, ASN39B, ASN71B, ASP35B, GLN33B, GLN69B, GLU124C, GLU46B, GLY42B, HIS34B, ILE120C, ILE62B, ILE67B, LEU109B, LEU110C, LEU49B, LEU75B, LYS123C, LYS36B, LYS57B, LYS60B, MET66B, MET68B, PRO121C, PRO122C, PRO58B, SER111C, THR118C, THR41B, THR50B, THR53B, THR64B, TYR113C, TYR32B, TYR59B, TYR61B, VAL111B, VAL112C, VAL115C, VAL37B, VAL45B, VAL63B
• B-D: ALA110B, ALA117D, ALA73B, ALA78B, ARG94B, ASN109D, ASN114D, ASN119D, ASN71B, ASN84B, ASN85B, ASP86B, ASP88B, CYS102B, CYS81B, CYS91B, GLN116D, GLN69B, GLU124D, GLU96B, GLY72B, GLY74B, GLY89B, HIS76B, ILE103B, ILE120D, LEU109B, LEU110D, LEU75B, LYS123D, LYS70B, MET100B, MET66B, MET68B, PHE107B, PHE10B, PRO121D, PRO122D, SER105B, SER111D, SER79B, SER80B, SER90B, THR118D, THR125D, THR77B, THR87B, THR92B, TRP83B, TRP95B, TYR101B, TYR113D, TYR82B, VAL104B, VAL106B, VAL112D, VAL115D, VAL12B, VAL93B
• C-E: ALA11E, ALA82E, ARG60E, ARG71E, ASN10E, ASN61E, ASP12E, GLN131C, GLN133C, GLN80E, GLU124C, GLU69E, GLY59E, GLY63E, GLY89E, HIS68E, HIS72E, ILE57E, ILE74E, ILE83E, LEU126C, LEU84E, LEU85E, LYS130C, LYS87E, LYS9E, MET13E, PHE62E, PHE73E, PHE76E, PHE86E, SER64E, SER88E, THR125C, THR129C, THR132C, THR134C, THR135C, THR67E, THR70E, TYR128C, TYR65E, TYR75E, TYR77E, VAL127C, VAL58E, VAL66E, VAL81E
• C-F: ALA39F, ALA40F, ARG60F, ASN33F, ASN61F, ASP37F, ASP47F, CYS56F, GLN131C, GLN133C, GLU124C, GLU35F, GLY59F, GLY89F, HIS55F, ILE34F, ILE38F, ILE57F, LYS130C, LYS36F, LYS43F, LYS44F, PHE62F, PRO52F, SER88F, THR129C, THR132C, THR134C, THR135C, THR53F, TRP54F, TYR128C, TYR41F, VAL127C, VAL58F
• D-E: ALA39E, ALA40E, ARG60E, ASN33E, ASN61E, ASP37E, ASP47E, CYS56E, GLN131D, GLN133D, GLU35E, GLY59E, GLY89E, HIS55E, ILE34E, ILE38E, ILE57E, LYS130D, LYS36E, LYS43E, LYS44E, PHE62E, PRO52E, SER88E, THR125D, THR129D, THR132D, THR134D, THR53E, TRP54E, TYR128D, TYR41E, VAL127D, VAL58E
• D-F: ALA11F, ALA82F, ARG60F, ARG71F, ASN10F, ASN61F, ASP12F, GLN131D, GLN133D, GLN80F, GLU69F, GLY59F, GLY63F, GLY89F, HIS68F, HIS72F, ILE57F, ILE74F, ILE83F, LEU126D, LEU84F, LEU85F, LYS130D, LYS87F, LYS9F, PHE62F, PHE73F, PHE76F, PHE86F, SER64F, SER88F, THR125D, THR129D, THR132D, THR134D, THR135D, THR67F, THR70F, TYR128D, TYR65F, TYR75F, TYR77F, VAL127D, VAL58F, VAL66F, VAL81F
• E-F: ALA39E, ALA39F, ALA40E, ALA40F, ALA82E, ALA82F, ARG60E, ARG60F, ASN61E, ASN61F, ASP37E, ASP37F, ASP47E, ASP47F, CYS56E, CYS56F, GLN80E, GLU35E, GLU35F, GLU45E, GLU45F, GLU69E, GLU69F, GLY59E, GLY59F, GLY63E, GLY63F, GLY89E, GLY89F, HIS55E, HIS55F, HIS68E, HIS68F, ILE34E, ILE34F, ILE38E, ILE38F, ILE42E, ILE42F, ILE57E, ILE57F, ILE83F, LEU84E, LEU84F, LEU85E, LEU85F, LYS36E, LYS36F, LYS43E, LYS43F, LYS44E, LYS44F, LYS87E, LYS87F, LYS9F, PHE62E, PHE62F, PHE86E, PHE86F, PRO52E, PRO52F, SER64E, SER64F, SER88E, SER88F, THR53E, THR53F, THR67E, THR67F, TRP54E, TRP54F, TYR41E, TYR41F, TYR65E, TYR65F, VAL58E, VAL58F, VAL66E, VAL66F, VAL81E, VAL81F