3FJK

crystal structure of a66c mutant of human acidic fibroblast growth factor

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 51
  • Norm. En. per Res.: -4.7403
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-64.0741	0.0	-177.68	-241.7541	51	16	1	6804	0	30	57
A-C	0.0	10.4907	-99.3508	-88.8601	61	7	0	4772	0	14	20
A-D	0.0	0.0	-25.4765	-25.4765	25	0	0	1365	0	4	3
B-D	0.0	11.7874	-110.6	-98.8126	63	0	0	4931	0	14	20
C-D	-47.2521	0.0	-188.883	-236.1351	51	17	2	6844	0	29	53

Interface residues

• A-B: ARG88A, ARG88B, ASN106A, ASN106B, ASN2A, ASN2B, ASN92A, ASN92B, GLN127A, GLN127B, GLU104A, GLU104B, GLU90A, GLU90B, GLU91A, GLU91B, GLY126A, GLY126B, HIS124A, HIS124B, HIS1A, HIS1B, HIS93A, HIS93B, ILE130A, ILE130B, ILE98A, ILE98B, LEU131A, LEU131B, LEU3A, LEU3B, LEU89A, LEU89B, LYS105B, LYS128B, PHE108A, PHE108B, PHE1A, PHE1B, PRO4A, PRO4B, PRO5A, PRO5B, THR123B, THR96A, THR96B, TYR125A, TYR125B, TYR94A, TYR94B
• A-C: ARG35A, ARG37A, ARG37C, ASN18A, ASN7A, ASN7C, ASN92A, ASN92C, ASN95A, ASN95C, ASP36A, CYS16A, CYS16C, GLU90C, GLU91A, GLU91C, GLY19A, GLY20A, GLY20C, GLY6A, GLY6C, HIS21A, HIS93A, HIS93C, LEU131A, LEU131C, LEU133A, LEU133C, LEU135A, LEU135C, LEU13A, LEU13C, LEU3C, LEU89A, LEU89C, LYS10C, LYS113A, LYS128A, LYS128C, LYS12A, LYS12C, PHE132C, PHE22A, PHE22C, PRO134A, PRO134C, PRO136A, PRO136C, PRO4A, PRO4C, PRO5A, PRO5C, SER17A, SER17C, SER38A, TYR15A, TYR15C, TYR94A, TYR94C, VAL137A, VAL137C
• A-D: ASN2A, ASN2D, ASN7A, ASN7D, ASN92A, ASN92D, GLU91A, GLU91D, GLY6A, GLY6D, HIS93A, HIS93D, LEU3A, LEU3D, LEU89A, LEU89D, LYS10A, LYS9A, LYS9D, PRO4A, PRO4D, PRO5A, PRO5D, VAL51A, VAL51D
• B-D: ARG35D, ARG37B, ARG37D, ASN18D, ASN2B, ASN7B, ASN92B, ASN92D, ASN95B, ASN95D, ASP36D, CYS16B, CYS16D, GLU90B, GLU90D, GLU91B, GLU91D, GLY19D, GLY20B, GLY20D, GLY6B, GLY6D, HIS21D, HIS93B, HIS93D, LEU131B, LEU131D, LEU133B, LEU133D, LEU135B, LEU135D, LEU13B, LEU13D, LEU3B, LEU89B, LEU89D, LYS10B, LYS113D, LYS128B, LYS128D, LYS12B, LYS12D, LYS9B, PHE132B, PHE132D, PHE22B, PHE22D, PRO134B, PRO134D, PRO136B, PRO136D, PRO4B, PRO4D, PRO5B, PRO5D, SER17B, SER17D, TYR15B, TYR15D, TYR94B, TYR94D, VAL137B, VAL137D
• C-D: ARG88C, ARG88D, ASN106C, ASN106D, ASN2C, ASN2D, ASN92C, ASN92D, ASN95D, GLN127C, GLN127D, GLU104C, GLU104D, GLU90C, GLU90D, GLU91C, GLU91D, GLY126C, GLY126D, HIS124C, HIS124D, HIS1C, HIS1D, HIS93C, HIS93D, ILE130C, ILE130D, ILE98C, ILE98D, LEU131C, LEU131D, LEU3C, LEU3D, LEU89C, LEU89D, LYS128C, PHE108C, PHE108D, PHE1C, PHE1D, PRO4C, PRO4D, PRO5C, PRO5D, THR96C, THR96D, TYR125C, TYR125D, TYR94C, TYR94D, VAL51D